메뉴 건너뛰기




Volumn 275, Issue 6 44-6, 1998, Pages

Sepsis in mice stimulates muscle proteolysis in the absence of IL-6

Author keywords

Cytokines; Interleukin 6 knockout mice; Myofibrillar proteins; Myotubes; Protein breakdown; Ubiquitin

Indexed keywords

CYTOKINE; MESSENGER RNA; MUSCLE PROTEIN; RECOMBINANT INTERLEUKIN 6; UBIQUITIN;

EID: 0032430097     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.1998.275.6.r1983     Document Type: Article
Times cited : (38)

References (40)
  • 1
    • 0023277545 scopus 로고
    • Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski, P., and N. Sacchi. Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 156-159, 1987.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 2
    • 0028018268 scopus 로고
    • The ubiquitin-proteasome pathway
    • Ciechanover, A. The ubiquitin-proteasome pathway. Cell 79: 13-21, 1994.
    • (1994) Cell , vol.79 , pp. 13-21
    • Ciechanover, A.1
  • 3
    • 0020699776 scopus 로고
    • Muscle proteolysis induced by a circulating peptide in patients with sepsis or trauma
    • Clowes, G. H. A., B. C. George, C. A. Villee, and C. A. Saravis. Muscle proteolysis induced by a circulating peptide in patients with sepsis or trauma. N. Engl. J. Med. 308: 545-552, 1983.
    • (1983) N. Engl. J. Med. , vol.308 , pp. 545-552
    • Clowes, G.H.A.1    George, B.C.2    Villee, C.A.3    Saravis, C.A.4
  • 5
    • 0029818204 scopus 로고    scopus 로고
    • Ciliary neurotrophic factor is catabolic and shares with IL-6 the cap'acity to induce an acute phase response
    • Regulatory Integrative Comp. Physiol. 40
    • Espat, N. J., T. Auffenberg, J. J. Rosenberg, M. Rogy, D. Martin, C. H. Fang, P. O. Hasseigren, E. M. Copeland, and L. L. Moldawer. Ciliary neurotrophic factor is catabolic and shares with IL-6 the cap'acity to induce an acute phase response. Am. J. Physiol. 271 (Regulatory Integrative Comp. Physiol. 40): R185-R190, 1996.
    • (1996) Am. J. Physiol. , vol.271
    • Espat, N.J.1    Auffenberg, T.2    Rosenberg, J.J.3    Rogy, M.4    Martin, D.5    Fang, C.H.6    Hasseigren, P.O.7    Copeland, E.M.8    Moldawer, L.L.9
  • 6
    • 0028817382 scopus 로고
    • Burn injury stimulates multiple proteolytic pathways in skeletal muscle including the ubiquitin-energy-dependent pathway
    • Fang, C. H., G. Tiao, J. H. James, C. K. Ogle, J. E. Fischer, and P. O. Hasselgren. Burn injury stimulates multiple proteolytic pathways in skeletal muscle including the ubiquitin-energy-dependent pathway. J. Am. Coll. Surg. 180: 161-170, 1995.
    • (1995) J. Am. Coll. Surg. , vol.180 , pp. 161-170
    • Fang, C.H.1    Tiao, G.2    James, J.H.3    Ogle, C.K.4    Fischer, J.E.5    Hasselgren, P.O.6
  • 8
    • 0028009670 scopus 로고
    • Interleukin-6 does not activate protein breakdown in rat skeletal muscle
    • Garcia-Martinez, C., F. J. Lopez-Soriano, and J. M. Argiles. Interleukin-6 does not activate protein breakdown in rat skeletal muscle. Cancer Lett. 76:1-4, 1994.
    • (1994) Cancer Lett. , vol.76 , pp. 1-4
    • Garcia-Martinez, C.1    Lopez-Soriano, F.J.2    Argiles, J.M.3
  • 10
    • 0016420707 scopus 로고
    • In vitro preparation of the diaphragm and other skeletal muscles
    • Goldberg, A- L., S. Martel, and M. Kuschmerick. In vitro preparation of the diaphragm and other skeletal muscles. Methods Enzymol. 39: 82-93, 1975.
    • (1975) Methods Enzymol. , vol.39 , pp. 82-93
    • Goldberg, A.L.1    Martel, S.2    Kuschmerick, M.3
  • 11
    • 0025790949 scopus 로고
    • Tumor necrosis factor induces skeletal muscle protein breakdown in rats
    • Endocrinol. Metab. 23
    • Goodman, M. N. Tumor necrosis factor induces skeletal muscle protein breakdown in rats. Am. J. Physiol. 260 (Endocrinol. Metab. 23): E727-E730,1991.
    • (1991) Am. J. Physiol. , vol.260
    • Goodman, M.N.1
  • 12
    • 0028201322 scopus 로고
    • Interleukin-6 induces skeletal muscle protein breakdown in rats
    • Goodman, M. N. Interleukin-6 induces skeletal muscle protein breakdown in rats. Proc. Soc. Exp. Biol. Med. 205: 182-185, 1994.
    • (1994) Proc. Soc. Exp. Biol. Med. , vol.205 , pp. 182-185
    • Goodman, M.N.1
  • 13
    • 0026080840 scopus 로고
    • Influence of sepsis in rats on muscle protein turnover in vivo and in tissue incubated under different in vitro conditions
    • Hall-Angerås, M., U. Angerås, D. vonAllmen, T. Higashiguchi, O. Zamir, P. O. Hasselgren, and J. E. Fischer. Influence of sepsis in rats on muscle protein turnover in vivo and in tissue incubated under different in vitro conditions. Metabolism 40: 247-251,1991.
    • (1991) Metabolism , vol.40 , pp. 247-251
    • Hall-Angerås, M.1    Angerås, U.2    Vonallmen, D.3    Higashiguchi, T.4    Zamir, O.5    Hasselgren, P.O.6    Fischer, J.E.7
  • 14
    • 0025761863 scopus 로고
    • Effect of the glucocorticoid receptor antagonist RU38386 on muscle protein breakdown in sepsis
    • Hall-Angerås, M., U. Angerås, O. Zamir, P. O. Hasselgren, and J. E. Fischer. Effect of the glucocorticoid receptor antagonist RU38386 on muscle protein breakdown in sepsis. Surgery 109: 468-473, 1991.
    • (1991) Surgery , vol.109 , pp. 468-473
    • Hall-Angerås, M.1    Angerås, U.2    Zamir, O.3    Hasselgren, P.O.4    Fischer, J.E.5
  • 15
    • 0348093742 scopus 로고
    • Methods commonly used to study protein metabolism
    • edited by P. O. Hasselgren. Austin, TX: Landes
    • Hasselgren, P. O. Methods commonly used to study protein metabolism. In: Protein Metabolism in Sepsis, edited by P. O. Hasselgren. Austin, TX: Landes, 1993, p. 10-33.
    • (1993) Protein Metabolism in Sepsis , pp. 10-33
    • Hasselgren, P.O.1
  • 16
    • 0025366346 scopus 로고
    • Regulation of total and myofibrillar protein breakdown in rat extensor digitorum longus and soleus muscle incubated flaccid and at resting length
    • Hasselgren, P. O., M. Hall-Angerås, U. Angerås, D. W. Benson, J. H. James, and J. E. Fischer. Regulation of total and myofibrillar protein breakdown in rat extensor digitorum longus and soleus muscle incubated flaccid and at resting length. Biochem. J. 267:37-44,1990.
    • (1990) Biochem. J. , vol.267 , pp. 37-44
    • Hasselgren, P.O.1    Hall-Angerås, M.2    Angerås, U.3    Benson, D.W.4    James, J.H.5    Fischer, J.E.6
  • 17
    • 0024386017 scopus 로고
    • Total and myofibrillar protein breakdown in different types of rat skeletal muscle: Effects of sepsis and regulation of insulin
    • Hasselgren, P. O., J. H. James, D. W. Benson, M. HallAngerås, D. T. Hiyama, S. Li, and J. E. Fischer. Total and myofibrillar protein breakdown in different types of rat skeletal muscle: effects of sepsis and regulation of insulin. Metabolism 38: 634-640,1989.
    • (1989) Metabolism , vol.38 , pp. 634-640
    • Hasselgren, P.O.1    James, J.H.2    Benson, D.W.3    Hallangerås, M.4    Hiyama, D.T.5    Li, S.6    Fischer, J.E.7
  • 18
    • 0031913331 scopus 로고    scopus 로고
    • The sepsis-induced increase in muscle proteolysis is blocked by specific proteasome inhibitors
    • Regulatory Integrative Comp. Physiol. 43
    • Hobler, S. C., G. Tiao, J. E. Fischer, J. Monaco, and P. O. Hasselgren. The sepsis-induced increase in muscle proteolysis is blocked by specific proteasome inhibitors. Am. J. Physiol. 274 (Regulatory Integrative Comp. Physiol. 43): R30-R37,1998.
    • (1998) Am. J. Physiol. , vol.274
    • Hobler, S.C.1    Tiao, G.2    Fischer, J.E.3    Monaco, J.4    Hasselgren, P.O.5
  • 19
    • 0028899142 scopus 로고
    • Effects of dexamethasone on protein degradation and protease gene expression in rat L8 myotube cultures
    • Hong, D. H., and N. E. Forsberg. Effects of dexamethasone on protein degradation and protease gene expression in rat L8 myotube cultures. Mol. Cell. Endocrinol. 108:199-209,1995.
    • (1995) Mol. Cell. Endocrinol. , vol.108 , pp. 199-209
    • Hong, D.H.1    Forsberg, N.E.2
  • 21
    • 0027240729 scopus 로고
    • Antibodies chaperone circulating IL-6: Paradoxical effects of anti-IL-6 "lizing" antibodies in vivo
    • May, L. T., R. Neta, L. L. Moldawer, J. S. Kenney, K. Patel, and P. B. Seghai. Antibodies chaperone circulating IL-6: paradoxical effects of anti-IL-6 "neutralizing" antibodies in vivo. J. Immunol. 151:3225-3236,1993.
    • (1993) J. Immunol. , vol.151 , pp. 3225-3236
    • May, L.T.1    Neta, R.2    Moldawer, L.L.3    Kenney, J.S.4    Patel, K.5    Seghai, P.B.6
  • 22
    • 0029000181 scopus 로고
    • Increase in levels of polyubiquitin and proteasome mRNA in skeletal muscle during starvation and denervation atrophy
    • Medina, R., S. S. Wing, and A. L. Goldberg. Increase in levels of polyubiquitin and proteasome mRNA in skeletal muscle during starvation and denervation atrophy. Biochem. J. 307: 631-637,1995.
    • (1995) Biochem. J. , vol.307 , pp. 631-637
    • Medina, R.1    Wing, S.S.2    Goldberg, A.L.3
  • 24
    • 0028212481 scopus 로고
    • Metabolic acidosis stimulates muscle protein degradation by activating the adenosine-triphosphate-dependent pathway involving ubiquitin and proteasomes
    • Mitch, W. E., R. Medina, S. Grieber, R. C. May, B. K. England, S. R. Price, J. L. Bailey, and A. L. Goldberg. Metabolic acidosis stimulates muscle protein degradation by activating the adenosine-triphosphate-dependent pathway involving ubiquitin and proteasomes. J. Clin. Invest. 93: 2127-2133, 1994.
    • (1994) J. Clin. Invest. , vol.93 , pp. 2127-2133
    • Mitch, W.E.1    Medina, R.2    Grieber, S.3    May, R.C.4    England, B.K.5    Price, S.R.6    Bailey, J.L.7    Goldberg, A.L.8
  • 27
    • 0026689535 scopus 로고
    • Evidence for the involvement of interleukin-6 in experimental cancer cachexia
    • Strassman, G., M. Fong, J. S. Kenney, and C. O. Jacob. Evidence for the involvement of interleukin-6 in experimental cancer cachexia. J. Clin. Invest. 89:1681-1684,1992.
    • (1992) J. Clin. Invest. , vol.89 , pp. 1681-1684
    • Strassman, G.1    Fong, M.2    Kenney, J.S.3    Jacob, C.O.4
  • 28
    • 1842339868 scopus 로고    scopus 로고
    • Inhibitors of the proteasome reduce the accelerated proteolysis in atrophying rat skeletal muscles
    • Tawa, N. E., R. Odessey, and A. L. Goldberg. Inhibitors of the proteasome reduce the accelerated proteolysis in atrophying rat skeletal muscles. J. Clin. Invest. 100:197-203,1997.
    • (1997) J. Clin. Invest. , vol.100 , pp. 197-203
    • Tawa, N.E.1    Odessey, R.2    Goldberg, A.L.3
  • 31
    • 0027973469 scopus 로고
    • Sepsis stimulates nonlysosomal, energy-dependent proteolysis and increases ubiquitin mRNA levels in rat skeletal muscle
    • Tiao, G., J. M. Fagan, N. Samuels, J. H. James, K. Hudson, M. Lieberman, J. E. Fischer, and P. O. Hasselgren. Sepsis stimulates nonlysosomal, energy-dependent proteolysis and increases ubiquitin mRNA levels in rat skeletal muscle. J. Clin. Invest. 94:2255-2264,1994.
    • (1994) J. Clin. Invest. , vol.94 , pp. 2255-2264
    • Tiao, G.1    Fagan, J.M.2    Samuels, N.3    James, J.H.4    Hudson, K.5    Lieberman, M.6    Fischer, J.E.7    Hasselgren, P.O.8
  • 32
    • 0031018516 scopus 로고    scopus 로고
    • Sepsis is associated with increased mRNAs of the ubiquitin-proteasome proteolytic pathway in human skeletal muscle
    • Tiao, G., S. Hobler, J. J. Wang, T. A. Meyer, F. A. Luchette, J. E. Fischer, and P. O. Hasselgren. Sepsis is associated with increased mRNAs of the ubiquitin-proteasome proteolytic pathway in human skeletal muscle. J. Clin. Invest. 99: 163-168, 1997.
    • (1997) J. Clin. Invest. , vol.99 , pp. 163-168
    • Tiao, G.1    Hobler, S.2    Wang, J.J.3    Meyer, T.A.4    Luchette, F.A.5    Fischer, J.E.6    Hasselgren, P.O.7
  • 33
    • 0030951073 scopus 로고    scopus 로고
    • Intracellular regulation of protein degradation during sepsis is different in fast- And slow-twitch muscle
    • Regulatory Integrative Comp. Physiol. 41
    • Tiao, G., M. Lieberman, J. E. Fischer, and P. O. Hasselgren. Intracellular regulation of protein degradation during sepsis is different in fast- and slow-twitch muscle. Am. J. Physiol. 272 (Regulatory Integrative Comp. Physiol. 41): R849-R856,1997.
    • (1997) Am. J. Physiol. , vol.272
    • Tiao, G.1    Lieberman, M.2    Fischer, J.E.3    Hasselgren, P.O.4
  • 36
    • 0031032016 scopus 로고    scopus 로고
    • Treatment of endotoxemic mice with IL-6 antibody paradoxically increases IL-6 levels and stimulates mucosal protein synthesis
    • Wang, Q., J. E. Fischer, and P. O. Hasselgren. Treatment of endotoxemic mice with IL-6 antibody paradoxically increases IL-6 levels and stimulates mucosal protein synthesis. Arch. Surg. 132:82-88,1997.
    • (1997) Arch. Surg. , vol.132 , pp. 82-88
    • Wang, Q.1    Fischer, J.E.2    Hasselgren, P.O.3
  • 37
    • 0027460118 scopus 로고
    • Glucocorticoids activate the ATP-ubiquitin-dependent proteolytic system in skeletal muscle during fasting
    • Endocrinol. Metab. 27
    • Wing, S. S., and A. L. Goldberg. Glucocorticoids activate the ATP-ubiquitin-dependent proteolytic system in skeletal muscle during fasting. Am. J. Physiol. 264 (Endocrinol. Metab. 27): E668-E676,1993.
    • (1993) Am. J. Physiol. , vol.264
    • Wing, S.S.1    Goldberg, A.L.2
  • 38
    • 0000863905 scopus 로고
    • Tumor necrosis factor (TNF) and interleukin-1 (IL-1) induce muscle proteolysis through different mechanisms
    • Zamir, O., P. O. Hasselgren, T. Higashiguchi, J. A. Frederick, and J. E. Fischer. Tumor necrosis factor (TNF) and interleukin-1 (IL-1) induce muscle proteolysis through different mechanisms. Mediat. Inflam. 1:247-250,1992.
    • (1992) Mediat. Inflam. , vol.1 , pp. 247-250
    • Zamir, O.1    Hasselgren, P.O.2    Higashiguchi, T.3    Frederick, J.A.4    Fischer, J.E.5
  • 39
    • 0026557647 scopus 로고
    • Evidence that tumor necrosis factor participates in the regulation of muscle proteolysis during sepsis
    • Zamir, O., P. O. Hasselgren, S. L. Kunkel, J. A. Frederick, T. Higashiguchi, and J. E. Fischer. Evidence that tumor necrosis factor participates in the regulation of muscle proteolysis during sepsis. Arch. Surg. 127:170-179,1992.
    • (1992) Arch. Surg. , vol.127 , pp. 170-179
    • Zamir, O.1    Hasselgren, P.O.2    Kunkel, S.L.3    Frederick, J.A.4    Higashiguchi, T.5    Fischer, J.E.6
  • 40
    • 0028180058 scopus 로고
    • Reduced muscle protein breakdown in septic rats following treatment with interleukin-1 receptor antagonist
    • Zamir, O., W. O'Brien, R. Thompson, D. C. Bloedow, J. E. Fischer, and P. O. Hasselgren. Reduced muscle protein breakdown in septic rats following treatment with interleukin-1 receptor antagonist. Int. J. Biochem. 26:943-950,1994.
    • (1994) Int. J. Biochem. , vol.26 , pp. 943-950
    • Zamir, O.1    O'Brien, W.2    Thompson, R.3    Bloedow, D.C.4    Fischer, J.E.5    Hasselgren, P.O.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.