Are the immune responses different in middle-aged and young mice following bone fracture, tissue trauma and hemorrhage?

Cytokine

Volumn 26, Issue 5, 2004, Pages 223-230

  Kang, Shih Ching ^a   Matsutani, Takeshi ^a   Choudhry, Mashkoor A ^a   Schwacha, Martin G ^a   Rue, Loring W ^a   Bland, Kirby I ^a   Chaudry, Irshad H ^a  

^a Kentucky   (United States)

Author keywords

Bone morrow; Cytokines; Kupffer cell; Proliferation; Splenocyte

Indexed keywords

CONCANAVALIN A; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; RINGER LACTATE SOLUTION;

ACUTE PHASE RESPONSE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLEEDING TENDENCY; BONE MARROW CELL; CELL PROLIFERATION; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; HEMORRHAGIC SHOCK; IMMUNOREGULATION; INFECTION SENSITIVITY; KUPFFER CELL; LIMB FRACTURE; MACROPHAGE FUNCTION; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; RESUSCITATION; SEPSIS; SHAM FEEDING; SOFT TISSUE INJURY; SPECIES COMPARISON; SPLEEN CELL; TH1 CELL; TH2 CELL;

AGE FACTORS; ANIMALS; BONE MARROW CELLS; CELL DIVISION; FRACTURES, BONE; HEMORRHAGE; INTERLEUKIN-10; INTERLEUKIN-6; KUPFFER CELLS; MICE; SOFT TISSUE INJURIES; SPLEEN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 2442552934     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cyto.2004.03.005     Document Type: Article

References (30)

1. Chaudry I.H., Ayala A. Immunological aspect of hemorrhage. 1992;R.G. Landes Co. Texas
2. Chaudry I.H., Ayala A., Ertel W., Stephan R.N. Hemorrhage and resuscitation: immunological aspects. Am J Physiol. 259:1990;R663-R678
3. Zellweger R., Ayala A., DeMaso C.M., Chaudry I.H. Trauma-hemorrhage causes prolonged depression in cellular immunity. Shock. 4:1995;149-153
4. Wichmann M.W., Zellweger R., DeMaso C.M., Ayala A., Williams C., Chaudry I.H. Immune function is more compromised after closed bone fracture and hemorrhagic shock than hemorrhage alone. Arch Surg. 131:1996;995-1000
5. Wichmann M.W., Ayala A., Chaudry I.H. Severe depression of host immune functions following closed-bone fracture, soft-tissue trauma, and hemorrhagic shock. Crit Care Med. 26:1998;1372-1378
6. Nickel E.A., Schwacha M.G., Schneider C.P., Bland K.I., Chaudry I.H. Trauma-hemorrhage-induced alterations in thymic prolactin receptor expression: implications in immune dysfunction. Cytokine. 18:2002;127-132
7. Morris J.A. Jr., MacKenzie E.J., Damiano A.M., Bass S.M. Mortality in trauma patients: the interaction between host factors and severity. J Trauma. 30:1990;1476-1482
8. Gannon C.J., Napolitano L.M., Pasquale M., Tracy J.K., McCarter R.J. A statewide population-based study of gender differences in trauma: validation of a prior single-institution study. J Am Coll Surg. 195:2002;11-18
9. George R.L., McGwin G. Jr., Windham S.T., Melton S.M., Metzger J., Chaudry I.H., et al. Age-related gender differential in outcome after blunt or penetrating trauma. Shock. 19:2003;28-32
10. Wohltmann C.D., Franklin G.A., Boaz P.W., Luchette F.A., Kearney P.A., Richardson J.D., et al. A multicenter evaluation of whether gender dimorphism affects survival after trauma. Am J Surg. 181:2001;297-300
11. Meyers B.R., Sherman E., Mendelson M.H., Velasquez G., Srulevitch-Chin E., Hubbard M., et al. Bloodstream infections in the elderly. Am J Med. 86:1989;379-384
12. Miller R.A. The aging immune system: primer and prospectus. Science. 273:1996;70-74
13. Tateda K., Matsumoto T., Miyazaki S., Yamaguchi K. Lipopolysaccharide- induced lethality and cytokine production in aged mice. Infect Immun. 64:1996;769-774
14. Johnson K.M., Owen K., Witte P.L. Aging and developmental transitions in the B cell lineage. Int Immunol. 14:2002;1313-1323
15. Linton P.J., Haynes L., Klinman N.R., Swain S.L. Antigen-independent changes in naive CD4 T cells with aging. J Exp Med. 184:1996;1891-1900
16. Kahlke V., Angele M.K., Ayala A., Schwacha M.G., Cioffi W.G., Bland K.I., et al. Immune dysfunction following trauma-hemorrhage: influence of gender and age. Cytokine. 12:2000;69-77
17. Kahlke V., Angele M.K., Schwacha M.G., Ayala A., Cioffi W.G., Bland K.I., et al. Reversal of sexual dimorphism in splenic T lymphocyte responses after trauma-hemorrhage with aging. Am J Physiol Cell Physiol. 278:2000;C509-C516
18. Wichmann M.W., Ayala A., Chaudry I.H. Male sex steroids are responsible for depressing macrophage immune function after trauma-hemorrhage. Am J Physiol. 273:1997;C1335-C1340
19. Angele M.K., Knoferl M.W., Schwacha M.G., Ayala A., Cioffi W.G., Bland K.I., et al. Sex steroids regulate pro- and anti-inflammatory cytokine release by macrophages after trauma-hemorrhage. Am J Physiol. 277:1999;C35-C42
20. Brouwer A., Parker S.G., Hendriks H.F., Gibbons L., Horan M.A. Production of eicosanoids and cytokines by Kupffer cells from young and old rats stimulated by endotoxin. Clin Sci. 88:1995;211-217
21. Flohe S., Ackermann M., Reuter M., Nast-Kolb D., Schade F.U. Sub lethal hemorrhagic shock reduces tumor necrosis factor α-producing capacity in different cell compartments. Eur Cytokine Netw. 11:2000;420-426
22. Schneider C.P., Schwacha M.G., Matsutani T., Bland K.I., Chaudry I.H. Early IL-10 release regulates the proinflammatory response after trauma-hemorrhage. Shock. 17:(Suppl 1):2002;56
23. Wichmann M.W., Zellweger R., DeMaso C.M., Ayala A., Chaudry I.H. Mechanism of immunosuppression in males following trauma-hemorrhage. Critical role of testosterone. Arch Surg. 131:1996;1186-1192
24. Ayala A., O'Neill P.J., Uebele S.A., Herdon C.D., Chaudry I.H. Mechanism of splenic immunosuppression during sepsis: key role of Kupffer cell mediators. J Trauma. 42:1997;882-888
25. O'Neill P.J., Ayala A., Wang P., Ba Z.F., Morrison M.H., Schultze A.E., et al. Role of Kupffer cells in interleukin-6 release following trauma-hemorrhage and resuscitation. Shock. 1:1994;43-47
26. Angele M.K., Schwacha M.G., Ayala A., Chaudry I.H. Effect of gender and sex hormones on immune responses following shock. Shock. 14:2000;81-90
27. Angele M.K., Knoferl M.W., Ayala A., Bland K.I., Chaudry I.H. Testosterone and estrogen differently effect Th1 and Th2 cytokine release following trauma-haemorrhage. Cytokine. 6:2001;22-30
28. Straub R.H., Miller L.E., Scholmerich J., Zietz B. Cytokines and hormones as possible links between endocrinosenescence and immunosenescence. J Neuroimmunol. 109:2000;10-15
29. Ershler W.B., Keller E.T. Age-associated increased interleukin-6 gene expression, late-life disease, and frailty. Annu Rev Med. 51:2000;245-270
30. Ferrari E., Cravello L., Muzzoni B., Casarotti D., Paltro M., Solerte S.B., et al. Age-related changes of the hypothalamic-pituitary-adrenal axis: pathophysiological correlates. Eur J Endocrinol. 144:2001;319-329