Biosynthetic modularity rules in the bisintercalator family of antitumor compounds

Marine Drugs

Volumn 12, Issue 5, 2014, Pages 2668-2699

  Fernández, Javier ^a   Marín, Laura ^a   Álvarez Alonso, Raquel ^a   Redondo, Saúl ^a   Carvajal, Juan ^a   Villamizar, Germán ^a   Villar, Claudio J ^a   Lombó, Felipe ^a  

^a DEPARTAMENTO DE BIOQUÍMICA Y BIOLOGÍA MOLECULAR   (Spain)

Author keywords

3 hydroxy quinaldic acid; Actinomycete; Antibiotic; Antitumor; Antiviral; Bisintercalator; Depsipeptide; Non ribosomal peptide; Quinoxaline 2 carboxilic acid; Thiodepsipeptide

Indexed keywords

AMINO ACID; ANTINEOPLASTIC AGENT; ECHINOMYCIN; INTERCALATING AGENT; QUINOMYCIN; SW 163; THIOCORALINE; TRIOSTIN; UNCLASSIFIED DRUG; ANTINEOPLASTIC ANTIBIOTIC;

ACTINOBACTERIA; AMINO ACID SEQUENCE; ANTIBACTERIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIVIRAL ACTIVITY; CHROMATOPHORE; DNA HELIX; DRUG ACTIVITY; DRUG DEVELOPMENT; DRUG STRUCTURE; GENE CLUSTER; GENETIC ENGINEERING; HUMAN; MOLECULAR EVOLUTION; NONHUMAN; PROTEIN FAMILY; PROTEIN SYNTHESIS; REVIEW; SEQUENCE HOMOLOGY; SYNTHESIS; ANIMAL; BIOSYNTHESIS; CHEMISTRY; METABOLISM; STRUCTURE ACTIVITY RELATION;

ACTINOBACTERIA; ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; HUMANS; INTERCALATING AGENTS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84901412720     PISSN: None     EISSN: 16603397     Source Type: Journal    
DOI: 10.3390/md12052668     Document Type: Review

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