Quinoxapeptins: Novel chromodepsipeptide inhibitors of HIV-1 and HIV-2 reverse transcriptase I. The producing organism and biological activity

Journal of Antibiotics

Volumn 49, Issue 3, 1996, Pages 253-259

  Lingham, Russell B ^a   Hsu, Amy H M ^a   O'Brien, Julie A ^a   Sigmund, Janet M ^a   Sanchez, Manuel ^b   Gagliardi, Magda M ^a   Heimbuch, Brian K ^a   Genilloud, Olga ^b   Martin, Isabel ^b   Diez, Maria T ^b   Hirsch, Charles F ^a   Zink, Deborah L ^a   Liesch, Jerrold M ^a   Koch, Gregory E ^a   Gartner, Suzanne E ^a   Garrity, George M ^a   Tsou, Nancy N ^a   Salituro, Gino M ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b Medical affairs Merck sharp and Dohme ltd   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; DNA DIRECTED DNA POLYMERASE ALPHA; DNA DIRECTED DNA POLYMERASE BETA; DNA DIRECTED DNA POLYMERASE DELTA; DNA DIRECTED DNA POLYMERASE GAMMA; ISOENZYME; LUZOPEPTIN A; QUINOXAPEPTIN DERIVATIVE; RNA DIRECTED DNA POLYMERASE; UNCLASSIFIED DRUG; VIRUS ENZYME;

ACTINOBACTERIA; ANTIBIOTIC BIOSYNTHESIS; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG SPECIFICITY; DRUG STRUCTURE; ENZYME INHIBITION; FERMENTATION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2; NONHUMAN; PRIORITY JOURNAL; TAXONOMY;

ACTINOMYCETALES; DNA-DIRECTED DNA POLYMERASE; HIV-1; HIV-1 REVERSE TRANSCRIPTASE; HIV-2; HUMANS; HYDROXYQUINOLINES; KINETICS; MOLECULAR STRUCTURE; MUTATION; PEPTIDES, CYCLIC; QUINOXALINES; REVERSE TRANSCRIPTASE INHIBITORS; RNA-DIRECTED DNA POLYMERASE;

EID: 0029983711     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.49.253     Document Type: Article

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