A New Scaffold of an Old Protein Fold Ensures Binding to the Bisintercalator Thiocoraline

Journal of Molecular Biology

Volumn 397, Issue 2, 2010, Pages 495-507

  Biswas, Tapan ^a   Zolova, Olga E ^a   Lombó, Felipe ^b   de la Calle, Fernando ^c   Salas, Jose A ^b   Tsodikov, Oleg V ^a   Garneau Tsodikova, Sylvie ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b DEPARTAMENTO DE BIOQUÍMICA Y BIOLOGÍA MOLECULAR   (Spain)

^c PHARMAMAR S A   (Spain)

Author keywords

bacterial resistance; bisintercalator; hydrophobic pocket; thiocoraline; tryptophan fluorescence

Indexed keywords

BACTERIAL PROTEIN; PROTEIN TIOX; QUINALDIC ACID; SCAFFOLD PROTEIN; THIOCORALINE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL STRAIN; CRYSTAL STRUCTURE; DISULFIDE BOND; GENE CLUSTER; MOLECULAR EVOLUTION; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN MOTIF; PROTEIN SECRETION; PROTEIN STABILITY; STREPTOMYCES ALBUS;

BACTERIA (MICROORGANISMS); STREPTOMYCES ALBUS;

EID: 77349124415     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2010.01.053     Document Type: Article

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