The cytoprotective effect of sulfuretin against tert-Butyl Hydroperoxide-induced hepatotoxicity through Nrf2/ARE and JNK/ERK MAPK-mediated Heme Oxygenase-1 expression

International Journal of Molecular Sciences

Volumn 15, Issue 5, 2014, Pages 8863-8877

  Lee, Dong Sung ^a   Kim, Kyoung Su ^a   Ko, Wonmin ^a   Li, Bin ^b   Jeong, Gil Saeng ^c   Jang, Jun Hyeog ^d   Oh, Hyuncheol ^a   Kim, Youn Chul ^a  

^a Wonkwang University   (South Korea)

^b QINGDAO UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c Keimyung University   (South Korea)

^d Inha University School of Medicine   (South Korea)

Author keywords

Heme oxygenase 1; Hepatoprotective; HepG2 cells; Oxidative stress; Rhus verniciflua stokes; Sulfuretin; Tert butyl hydroperoxide

Indexed keywords

HEME OXYGENASE 1; LIVER PROTECTIVE AGENT; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; SULFURETIN; TERT BUTYL HYDROPEROXIDE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; 2-(2-AMINO-3-METHOXYPHENYL)-4H-1-BENZOPYRAN-4-ONE; ANTHRA(1,9-CD)PYRAZOL-6(2H)-ONE; ANTHRACENE DERIVATIVE; BENZOFURAN DERIVATIVE; FLAVONOID; MITOGEN ACTIVATED PROTEIN KINASE; PROTECTIVE AGENT;

ANACARDIACEAE; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; CELL PROTECTION; CELL VIABILITY ASSAY; CONTROLLED STUDY; GENETIC TRANSFECTION; HEPG2 CELL LINE; HUMAN; HUMAN CELL; LIVER TOXICITY; LUCIFERASE ASSAY; MTT ASSAY; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING; ANTAGONISTS AND INHIBITORS; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; GENETICS; METABOLISM; PHOSPHORYLATION; TOXICITY;

ANTHRACENES; ANTIOXIDANT RESPONSE ELEMENTS; BENZOFURANS; CELL SURVIVAL; FLAVONOIDS; HEME OXYGENASE-1; HEP G2 CELLS; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; PHOSPHORYLATION; PROTECTIVE AGENTS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TERT-BUTYLHYDROPEROXIDE; UP-REGULATION;

EID: 84901036262     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms15058863     Document Type: Article

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