In vivo metabolism of tert-Butyl hydroperoxide to methyl radicals. EPR spin-trapping and DNA methylation studies

Chemical Research in Toxicology

Volumn 13, Issue 10, 2000, Pages 1056-1064

  Hix, S ^a   Kadiiska, M B ^b   Mason, R P ^b   Augusto, O ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

7 METHYLGUANINE; FREE RADICAL; GUANINE DERIVATIVE; N TERT BUTYL ALPHA PHENYLNITRONE; NITRONE DERIVATIVE; TERT BUTYL HYDROPEROXIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARCINOGENICITY; CONTROLLED STUDY; DNA ADDUCT; DNA ALKYLATION; DNA METHYLATION; ELECTRON SPIN RESONANCE; GENOTOXICITY; LIPID OXIDATION; LIVER; MALE; METABOLISM; NONHUMAN; RAT; SPIN TRAPPING; STOMACH;

ANIMALS; DNA; DNA METHYLATION; FREE RADICALS; GUANOSINE; INDICATORS AND REAGENTS; LIVER; MALE; NITROGEN OXIDES; RATS; RATS, WISTAR; SPIN TRAPPING; STOMACH; TERT-BUTYLHYDROPEROXIDE;

EID: 0033789365     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx000130l     Document Type: Article

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