The α-methylene-γ-butyrolactone moiety in dehydrocostus lactone is responsible for cytoprotective heme oxygenase-1 expression through activation of the nuclear factor E2-related factor 2 in HepG2 cells

European Journal of Pharmacology

Volumn 565, Issue 1-3, 2007, Pages 37-44

  Jeong, Gil Saeng ^a   Pae, Hyun Ock ^a   Jeong, Sun Oh ^a   Kim, Youn Chul ^a   Kwon, Tae Oh ^a   Lee, Ho Sub ^a   Kim, Nam Song ^a   Park, Seok Don ^a   Chung, Hun Taeg ^a  

^a Wonkwang University   (South Korea)

Author keywords

Methylene butyrolactone; Antioxidant response element; Dehydrocostus lactone; Heme oxygenase 1; Nuclear factor E2 related factor 2; Protection; Saussurea lappa

Indexed keywords

ALPHA METHYLENE BUTYROLACTONE; BUTYROLACTONE; DEHYDROCOSTUS LACTONE; HEME OXYGENASE 1; HYDROGEN PEROXIDE; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ANTIOXIDANT ACTIVITY; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; CYTOTOXICITY; HUMAN; HUMAN CELL; MEDICINAL PLANT; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SAUSSUREA LAPPA;

4-BUTYROLACTONE; ACTIVE TRANSPORT, CELL NUCLEUS; ANTIOXIDANTS; CELL LINE; CYTOPROTECTION; HEME OXYGENASE-1; HUMANS; LACTONES; NF-E2-RELATED FACTOR 2; RESPONSE ELEMENTS; SESQUITERPENES;

EID: 34249101215     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2007.02.053     Document Type: Article

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