Structural biology of the IL-1 superfamily: Key cytokines in the regulation of immune and inflammatory responses

Protein Science

Volumn 23, Issue 5, 2014, Pages 526-538

  Krumm, Brian ^a   Xiang, Yan ^b   Deng, Junpeng ^a  

^a OKLAHOMA STATE UNIVERSITY   (United States)

^b University of Texas Health Science Center   (United States)

Author keywords

Agonist; Antagonist; Cytokine; Inflammation; Interleukin; Receptors

Indexed keywords

ADALIMUMAB; ETANERCEPT; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR ACCESSORY PROTEIN; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 18; INTERLEUKIN 18 BINDING PROTEIN; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 33; INTERLEUKIN RECEPTOR; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; TUMOR NECROSIS FACTOR; INTERLEUKIN-18 BINDING PROTEIN; SIGNAL PEPTIDE;

ADAPTIVE IMMUNITY; ALLERGY; ASTHMA; AUTOIMMUNE DISEASE; BINDING AFFINITY; BINDING SITE; CLINICAL TRIAL (TOPIC); CONFORMATIONAL TRANSITION; CROHN DISEASE; CRYSTAL STRUCTURE; ECTROMELIA VIRUS; HUMAN; IMMUNITY; IMMUNOMODULATION; INFLAMMATION; INNATE IMMUNITY; INTRACELLULAR SIGNALING; MOLECULAR RECOGNITION; MOLLUSCIPOXVIRUS; NONHUMAN; POXVIRUS; PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE; PROTEIN STRUCTURE; PSORIASIS; RECEPTOR BINDING; REGULATORY MECHANISM; REVIEW; RHEUMATOID ARTHRITIS; VACCINIA VIRUS; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMICAL STRUCTURE; CHEMISTRY; IMMUNOLOGY; PROTEIN CONFORMATION; SIGNAL TRANSDUCTION; X RAY CRYSTALLOGRAPHY;

ANIMALS; CRYSTALLOGRAPHY, X-RAY; HUMANS; INFLAMMATION; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; INTERLEUKIN-1; INTERLEUKIN-18; MODELS, MOLECULAR; PROTEIN CONFORMATION; SIGNAL TRANSDUCTION;

EID: 84901013877     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1002/pro.2441     Document Type: Review

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