Determination of the Functional Epitopes of Human Interleukin-18-binding Protein by Site-directed Mutagenesis

Journal of Biological Chemistry

Volumn 276, Issue 20, 2001, Pages 17380-17386

  Xiang, Yan ^b   Moss, Bernard ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

AFFINITY CHROMATOGRAPHY; AMINO ACIDS; BIOCHEMISTRY; CELLS; CHEMICAL BONDS; DISEASES; FREE ENERGY; HYDROPHOBICITY; IMMUNOLOGY; MUTAGENESIS;

EPITOPES;

PROTEINS;

ALANINE; CYTOKINE; HISTIDINE; INTERLEUKIN 18; INTERLEUKIN 18 BINDING PROTEIN; INTERLEUKIN 18 BINDING PROTEIN S; INTERLEUKIN 18 RECEPTOR; INTERLEUKIN 1BETA; MUTANT PROTEIN; STREPTAVIDIN; UNCLASSIFIED DRUG; EPITOPE; GLYCOPROTEIN; HYBRID PROTEIN; INTERLEUKIN-18 BINDING PROTEIN; RECOMBINANT PROTEIN; SIGNAL PEPTIDE;

AMINO ACID ANALYSIS; AMINO ACID SUBSTITUTION; ANIMAL CELL; ANTIMICROBIAL ACTIVITY; ARTICLE; BETA SHEET; BINDING AFFINITY; BINDING SITE; BIOTINYLATION; CARBOXY TERMINAL SEQUENCE; COMPUTER PREDICTION; CYTOKINE PRODUCTION; DNA MICROARRAY; DNA MODIFICATION; ENERGY; EPITOPE MAPPING; HUMAN; HUMAN CELL; HYDROPHOBICITY; IMMOBILIZED METAL AFFINITY CHROMATOGRAPHY; IN SITU HYBRIDIZATION; INFLAMMATION; MAMMAL CELL; MOLECULAR BIOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN SECRETION; RECEPTOR BLOCKING; SITE DIRECTED MUTAGENESIS; SURFACE PLASMON RESONANCE; AFFINITY CHROMATOGRAPHY; AMINO ACID SEQUENCE; ANIMAL; CELL LINE; CHEMISTRY; GENETICS; IMMUNOLOGY; ISOLATION AND PURIFICATION; KINETICS; MAMMAL; METABOLISM; MOLECULAR GENETICS; RESTRICTION MAPPING; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY;

ANIMALIA; MAMMALIA;

ALANINE; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; BIOTINYLATION; CELL LINE; CHROMATOGRAPHY, AFFINITY; EPITOPES; GLYCOPROTEINS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; INTERLEUKIN-18; KINETICS; MAMMALS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; RESTRICTION MAPPING; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0035907286     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M009581200     Document Type: Article

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