-
1
-
-
0029979369
-
Biologic basis for interleukin-1 in disease
-
Dinarello, C.A. Biologic basis for interleukin-1 in disease. Blood 87, 2095-2147 (1996).
-
(1996)
Blood
, vol.87
, pp. 2095-2147
-
-
Dinarello, C.A.1
-
2
-
-
34447324371
-
The expanding family of interleukin-1 cytokines and their role in destructive inflammatory disorders
-
Barksby, H.E., Lea, S.R., Preshaw, P.M. & Taylor, J.J. The expanding family of interleukin-1 cytokines and their role in destructive inflammatory disorders. Clin. Exp. Immunol. 149, 217-225 (2007).
-
(2007)
Clin. Exp. Immunol.
, vol.149
, pp. 217-225
-
-
Barksby, H.E.1
Lea, S.R.2
Preshaw, P.M.3
Taylor, J.J.4
-
3
-
-
62649139025
-
Immunological and inflammatory functions of the interleukin-1 family
-
Dinarello, C.A. Immunological and inflammatory functions of the interleukin-1 family. Annu. Rev. Immunol. 27, 519-550 (2009).
-
(2009)
Annu. Rev. Immunol.
, vol.27
, pp. 519-550
-
-
Dinarello, C.A.1
-
4
-
-
75549091673
-
The IL-1 family: Regulators of immunity
-
Sims, J.E. & Smith, D.E. The IL-1 family: regulators of immunity. Nat. Rev. Immunol. 10, 89-102 (2010).
-
(2010)
Nat. Rev. Immunol.
, vol.10
, pp. 89-102
-
-
Sims, J.E.1
Smith, D.E.2
-
5
-
-
0035471572
-
A new nomenclature for IL-1-family genes
-
Sims, J.E. et al. A new nomenclature for IL-1-family genes. Trends Immunol. 22, 536-537 (2001).
-
(2001)
Trends Immunol.
, vol.22
, pp. 536-537
-
-
Sims, J.E.1
-
6
-
-
77749304035
-
IL-1: Discoveries, controversies and future directions
-
Dinarello, C.A. IL-1: discoveries, controversies and future directions. Eur. J. Immunol. 40, 599-606 (2010).
-
(2010)
Eur. J. Immunol.
, vol.40
, pp. 599-606
-
-
Dinarello, C.A.1
-
7
-
-
0000814155
-
Nucleotide sequence of human monocyte interleukin 1 precursor cDNA
-
Auron, P.E. et al. Nucleotide sequence of human monocyte interleukin 1 precursor cDNA. Proc. Natl. Acad. Sci. USA 81, 7907-7911 (1984).
-
(1984)
Proc. Natl. Acad. Sci. USA
, vol.81
, pp. 7907-7911
-
-
Auron, P.E.1
-
8
-
-
0021745716
-
Cloning and expression of murine interleukin-1 cDNA in Escherichia coli
-
Lomedico, P.T. et al. Cloning and expression of murine interleukin-1 cDNA in Escherichia coli. Nature 312, 458-462 (1984).
-
(1984)
Nature
, vol.312
, pp. 458-462
-
-
Lomedico, P.T.1
-
9
-
-
0022364132
-
Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs
-
March, C.J. et al. Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs. Nature 315, 641-647 (1985).
-
(1985)
Nature
, vol.315
, pp. 641-647
-
-
March, C.J.1
-
10
-
-
0036398446
-
The IL-1 family and inflammatory diseases
-
Dinarello, C.A. The IL-1 family and inflammatory diseases. Clin. Exp. Rheumatol. 20, S1-S13 (2002).
-
(2002)
Clin. Exp. Rheumatol.
, vol.20
-
-
Dinarello, C.A.1
-
11
-
-
2642559875
-
Targeting IL-1 in inflammatory disease: New opportunities for therapeutic intervention
-
Braddock, M. & Quinn, A. Targeting IL-1 in inflammatory disease: new opportunities for therapeutic intervention. Nat. Rev. Drug Discov. 3, 330-339 (2004).
-
(2004)
Nat. Rev. Drug Discov.
, vol.3
, pp. 330-339
-
-
Braddock, M.1
Quinn, A.2
-
12
-
-
22244475444
-
The many worlds of reducing interleukin-1
-
Dinarello, C.A. The many worlds of reducing interleukin-1. Arthritis Rheum. 52, 1960-1967 (2005).
-
(2005)
Arthritis Rheum.
, vol.52
, pp. 1960-1967
-
-
Dinarello, C.A.1
-
13
-
-
73849134001
-
Blocking interleukin-1 in rheumatic diseases
-
Goldbach-Mansky, R. Blocking interleukin-1 in rheumatic diseases. Ann. NY Acad. Sci. 1182, 111-123 (2009).
-
(2009)
Ann. NY Acad. Sci.
, vol.1182
, pp. 111-123
-
-
Goldbach-Mansky, R.1
-
14
-
-
0023683844
-
CDNA expression cloning of the IL-1 receptor, a member of the immunoglobulin superfamily
-
Sims, J.E. et al. cDNA expression cloning of the IL-1 receptor, a member of the immunoglobulin superfamily. Science 241, 585-589 (1988).
-
(1988)
Science
, vol.241
, pp. 585-589
-
-
Sims, J.E.1
-
15
-
-
0029009910
-
Molecular cloning and characterization of a second subunit of the interleukin 1 receptor complex
-
Greenfeder, S.A. et al. Molecular cloning and characterization of a second subunit of the interleukin 1 receptor complex. J. Biol. Chem. 270, 13757-13765 (1995).
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 13757-13765
-
-
Greenfeder, S.A.1
-
16
-
-
0031013038
-
A critical role for interleukin-1 receptor accessory protein in interleukin-1 signaling
-
Korherr, C., Hofmeister, R., Wesche, H. & Falk, W. A critical role for interleukin-1 receptor accessory protein in interleukin-1 signaling. Eur. J. Immunol. 27, 262-267 (1997).
-
(1997)
Eur. J. Immunol.
, vol.27
, pp. 262-267
-
-
Korherr, C.1
Hofmeister, R.2
Wesche, H.3
Falk, W.4
-
17
-
-
0032533814
-
IL-1 receptor accessory protein is an essential component of the IL-1 receptor
-
Cullinan, E.B. et al. IL-1 receptor accessory protein is an essential component of the IL-1 receptor. J. Immunol. 161, 5614-5620 (1998).
-
(1998)
J. Immunol.
, vol.161
, pp. 5614-5620
-
-
Cullinan, E.B.1
-
18
-
-
0037465251
-
The interleukin-1 receptor/Toll-like receptor superfamily: Signal transduction during inflammation and host defense
-
Dunne, A. & ONeill, L.A. The interleukin-1 receptor/Toll-like receptor superfamily: signal transduction during inflammation and host defense. Sci. STKE 171, re3 (2003).
-
(2003)
Sci. STKE
, vol.171
-
-
Dunne, A.1
Oneill, L.A.2
-
19
-
-
0025899561
-
A novel IL-1 receptor, cloned from B cells by mammalian expression, is expressed in many cell types
-
McMahan, C.J. et al. A novel IL-1 receptor, cloned from B cells by mammalian expression, is expressed in many cell types. EMBO J. 10, 2821-2832 (1991).
-
(1991)
EMBO J.
, vol.10
, pp. 2821-2832
-
-
McMahan, C.J.1
-
20
-
-
0027181936
-
Interleukin-1 type II receptor: A decoy target for IL-1 that is regulated by IL-4
-
Colotta, F. et al. Interleukin-1 type II receptor: a decoy target for IL-1 that is regulated by IL-4. Science 261, 472-475 (1993).
-
(1993)
Science
, vol.261
, pp. 472-475
-
-
Colotta, F.1
-
21
-
-
0028004236
-
The type II decoy receptor: A novel regulatory pathway for interleukin 1
-
Colotta, F., Dower, S.K., Sims, J.E. & Mantovani, A. The type II decoy receptor: a novel regulatory pathway for interleukin 1. Immunol. Today 15, 562-566 (1994).
-
(1994)
Immunol. Today
, vol.15
, pp. 562-566
-
-
Colotta, F.1
Dower, S.K.2
Sims, J.E.3
Mantovani, A.4
-
22
-
-
0032534729
-
The type II IL-1 receptor interacts with the IL-1 receptor accessory protein: A novel mechanism of regulation of IL-1 responsiveness
-
Lang, D. et al. The type II IL-1 receptor interacts with the IL-1 receptor accessory protein: a novel mechanism of regulation of IL-1 responsiveness. J. Immunol. 161, 6871-6877 (1998).
-
(1998)
J. Immunol.
, vol.161
, pp. 6871-6877
-
-
Lang, D.1
-
23
-
-
0032537506
-
Interleukin-1 receptor accessory protein interacts with the type II interleukin-1 receptor
-
Malinowsky, D., Lundkvist, J., Laye, S. & Bartfai, T. Interleukin-1 receptor accessory protein interacts with the type II interleukin-1 receptor. FEBS Lett. 429, 299-302 (1998).
-
(1998)
FEBS Lett.
, vol.429
, pp. 299-302
-
-
Malinowsky, D.1
Lundkvist, J.2
Laye, S.3
Bartfai, T.4
-
24
-
-
33947727646
-
The interleukin-1 receptor family
-
Boraschi, D. & Tagliabue, A. The interleukin-1 receptor family. Vitam. Horm. 74, 229-254 (2006).
-
(2006)
Vitam. Horm.
, vol.74
, pp. 229-254
-
-
Boraschi, D.1
Tagliabue, A.2
-
25
-
-
0037237908
-
The soluble form of IL-1 receptor accessory protein enhances the ability of soluble type II IL-1 receptor to inhibit IL-1 action
-
Smith, D.E. et al. The soluble form of IL-1 receptor accessory protein enhances the ability of soluble type II IL-1 receptor to inhibit IL-1 action. Immunity 18, 87-96 (2003).
-
(2003)
Immunity
, vol.18
, pp. 87-96
-
-
Smith, D.E.1
-
26
-
-
0030998098
-
Crystal structure of the type-I interleukin-1 receptor complexed with interleukin-1β
-
Vigers, G.P., Anderson, L.J., Caffes, P. & Brandhuber, B.J. Crystal structure of the type-I interleukin-1 receptor complexed with interleukin-1β. Nature 386, 190-194 (1997).
-
(1997)
Nature
, vol.386
, pp. 190-194
-
-
Vigers, G.P.1
Anderson, L.J.2
Caffes, P.3
Brandhuber, B.J.4
-
27
-
-
0031000052
-
A new cytokine-receptor binding mode revealed by the crystal structure of the IL-1 receptor with an antagonist
-
Schreuder, H. et al. A new cytokine-receptor binding mode revealed by the crystal structure of the IL-1 receptor with an antagonist. Nature 386, 194-200 (1997).
-
(1997)
Nature
, vol.386
, pp. 194-200
-
-
Schreuder, H.1
-
28
-
-
0001031383
-
Structure-function relationship in the IL-1 family
-
Boraschi, D., Bossu, P., Macchia, G., Ruggiero, P. & Tagliabue, A. Structure-function relationship in the IL-1 family. Front. Biosci. 1, d270-d308 (1996).
-
(1996)
Front. Biosci.
, vol.1
-
-
Boraschi, D.1
Bossu, P.2
MacChia, G.3
Ruggiero, P.4
Tagliabue, A.5
-
29
-
-
0034711314
-
X-ray crystal structure of a small antagonist peptide bound to interleukin-1 receptor type 1
-
Vigers, G.P., Dripps, D.J., Edwards, C.K. III & Brandhuber, B.J. X-ray crystal structure of a small antagonist peptide bound to interleukin-1 receptor type 1. J. Biol. Chem. 275, 36927-36933 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 36927-36933
-
-
Vigers, G.P.1
Dripps, D.J.2
Edwards Iii, C.K.3
Brandhuber, B.J.4
-
30
-
-
0035876314
-
Model of interaction of the IL-1 receptor accessory protein IL-1RAcP with the IL-1β/IL-1R(I) complex
-
Casadio, R. et al. Model of interaction of the IL-1 receptor accessory protein IL-1RAcP with the IL-1β/IL-1R(I) complex. FEBS Lett. 499, 65-68 (2001).
-
(2001)
FEBS Lett.
, vol.499
, pp. 65-68
-
-
Casadio, R.1
-
31
-
-
70349759672
-
Structure of IL-33 and its interaction with the ST2 and IL-1RAcP receptors-insight into heterotrimeric IL-1 signaling complexes
-
Lingel, A. et al. Structure of IL-33 and its interaction with the ST2 and IL-1RAcP receptors-insight into heterotrimeric IL-1 signaling complexes. Structure 17, 1398-1410 (2009).
-
(2009)
Structure
, vol.17
, pp. 1398-1410
-
-
Lingel, A.1
-
32
-
-
0032055841
-
Antibodies to domains II and III of the IL-1 receptor accessory protein inhibit IL-1β activity but not binding: Regulation of IL-1 responses is via type i receptor, not the accessory protein
-
Yoon, D.Y. & Dinarello, C.A. Antibodies to domains II and III of the IL-1 receptor accessory protein inhibit IL-1β activity but not binding: regulation of IL-1 responses is via type I receptor, not the accessory protein. J. Immunol. 160, 3170-3179 (1998).
-
(1998)
J. Immunol.
, vol.160
, pp. 3170-3179
-
-
Yoon, D.Y.1
Dinarello, C.A.2
-
33
-
-
0028085946
-
Deletion mutants of human interleukin 1β with significantly reduced agonist properties: Search for the agonist/antagonist switch in ligands to the interleukin 1 receptors
-
Simoncsits, A. et al. Deletion mutants of human interleukin 1β with significantly reduced agonist properties: search for the agonist/antagonist switch in ligands to the interleukin 1 receptors. Cytokine 6, 206-214 (1994).
-
(1994)
Cytokine
, vol.6
, pp. 206-214
-
-
Simoncsits, A.1
-
34
-
-
0025890012
-
Conversion of the interleukin 1 receptor antagonist into an agonist by site-specific mutagenesis
-
Ju, G. et al. Conversion of the interleukin 1 receptor antagonist into an agonist by site-specific mutagenesis. Proc. Natl. Acad. Sci. USA 88, 2658-2662 (1991).
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 2658-2662
-
-
Ju, G.1
-
35
-
-
0031412632
-
Functional epitope mapping of human interleukin-1β by surface plasmon resonance
-
DEttorre, C., De Chiara, G., Casadei, R., Boraschi, D. & Tagliabue, A. Functional epitope mapping of human interleukin-1β by surface plasmon resonance. Eur. Cytokine Netw. 8, 161-171 (1997).
-
(1997)
Eur. Cytokine Netw.
, vol.8
, pp. 161-171
-
-
Dettorre, C.1
De Chiara, G.2
Casadei, R.3
Boraschi, D.4
Tagliabue, A.5
-
36
-
-
17744402452
-
Insertion of a structural domain of interleukin (IL)-1β confers agonist activity to the IL-1 receptor antagonist. Implications for IL-1 bioactivity
-
Greenfeder, S.A. et al. Insertion of a structural domain of interleukin (IL)-1β confers agonist activity to the IL-1 receptor antagonist. Implications for IL-1 bioactivity. J. Biol. Chem. 270, 22460-22466 (1995).
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 22460-22466
-
-
Greenfeder, S.A.1
-
37
-
-
0026525410
-
Structure-activity relationships in human interleukin-1β: Identification of key residues for expression of biological activities
-
Kawashima, H. et al. Structure-activity relationships in human interleukin-1β: identification of key residues for expression of biological activities. Protein Eng. 5, 171-176 (1992).
-
(1992)
Protein Eng.
, vol.5
, pp. 171-176
-
-
Kawashima, H.1
-
38
-
-
0030851728
-
Purification and characterization of the human interleukin-18 receptor
-
Torigoe, K. et al. Purification and characterization of the human interleukin-18 receptor. J. Biol. Chem. 272, 25737-25742 (1997).
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 25737-25742
-
-
Torigoe, K.1
-
39
-
-
0032491599
-
Cloning of a novel receptor subunit, AcPL, required for interleukin-18 signaling
-
Born, T.L., Thomassen, E., Bird, T.A. & Sims, J.E. Cloning of a novel receptor subunit, AcPL, required for interleukin-18 signaling. J. Biol. Chem. 273, 29445-29450 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 29445-29450
-
-
Born, T.L.1
Thomassen, E.2
Bird, T.A.3
Sims, J.E.4
-
40
-
-
0242407130
-
The structure and binding mode of interleukin-18
-
Kato, Z. et al. The structure and binding mode of interleukin-18. Nat. Struct. Biol. 10, 966-971 (2003).
-
(2003)
Nat. Struct. Biol.
, vol.10
, pp. 966-971
-
-
Kato, Z.1
-
41
-
-
0037192869
-
Identification of amino acid residues critical for biological activity in human interleukin-18
-
Kim, S.H. et al. Identification of amino acid residues critical for biological activity in human interleukin-18. J. Biol. Chem. 277, 10998-11003 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 10998-11003
-
-
Kim, S.H.1
-
42
-
-
0033974776
-
Structural requirements of six naturally occurring isoforms of the IL-18 binding protein to inhibit IL-18
-
Kim, S.H. et al. Structural requirements of six naturally occurring isoforms of the IL-18 binding protein to inhibit IL-18. Proc. Natl. Acad. Sci. USA 97, 1190-1195 (2000).
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 1190-1195
-
-
Kim, S.H.1
-
43
-
-
58549098246
-
Structural basis for antagonism of human interleukin 18 by poxvirus interleukin 18-binding protein
-
Krumm, B., Meng, X., Li, Y., Xiang, Y. & Deng, J. Structural basis for antagonism of human interleukin 18 by poxvirus interleukin 18-binding protein. Proc. Natl. Acad. Sci. USA 105, 20711-20715 (2008).
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 20711-20715
-
-
Krumm, B.1
Meng, X.2
Li, Y.3
Xiang, Y.4
Deng, J.5
-
44
-
-
69949161901
-
Unusual water-mediated antigenic recognition of the proinflammatory cytokine interleukin-18
-
Argiriadi, M.A., Xiang, T., Wu, C., Ghayur, T. & Borhani, D.W. Unusual water-mediated antigenic recognition of the proinflammatory cytokine interleukin-18. J. Biol. Chem. 284, 24478-24489 (2009).
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 24478-24489
-
-
Argiriadi, M.A.1
Xiang, T.2
Wu, C.3
Ghayur, T.4
Borhani, D.W.5
-
45
-
-
67649846643
-
Structural biology of shared cytokine receptors
-
Wang, X., Lupardus, P., Laporte, S.L. & Garcia, K.C. Structural biology of shared cytokine receptors. Annu. Rev. Immunol. 27, 29-60 (2009).
-
(2009)
Annu. Rev. Immunol.
, vol.27
, pp. 29-60
-
-
Wang, X.1
Lupardus, P.2
Laporte, S.L.3
Garcia, K.C.4
-
47
-
-
0028103275
-
The CCP4 suite: Programs for protein crystallography
-
Collaborative Computational Project, Number 4
-
Collaborative Computational Project, Number 4. The CCP4 suite: programs for protein crystallography. Acta Crystallogr. D Biol. Crystallogr. 50, 760-763 (1994).
-
(1994)
Acta Crystallogr. D Biol. Crystallogr.
, vol.50
, pp. 760-763
-
-
-
48
-
-
33744459472
-
Toward the structural genomics of complexes: Crystal structure of a PE/PPE protein complex from Mycobacterium tuberculosis
-
Strong, M. et al. Toward the structural genomics of complexes: crystal structure of a PE/PPE protein complex from Mycobacterium tuberculosis. Proc. Natl. Acad. Sci. USA 103, 8060-8065 (2006).
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 8060-8065
-
-
Strong, M.1
-
49
-
-
34447508216
-
Phaser crystallographic software
-
McCoy, A.J. et al. Phaser crystallographic software. J. Appl. Cryst. 40, 658-674 (2007).
-
(2007)
J. Appl. Cryst.
, vol.40
, pp. 658-674
-
-
McCoy, A.J.1
-
50
-
-
0024804106
-
Crystallographic refinement of interleukin 1β at 2.0 resolution
-
Priestle, J.P., Schar, H.P. & Grutter, M.G. Crystallographic refinement of interleukin 1β at 2.0 resolution. Proc. Natl. Acad. Sci. USA 86, 9667-9671 (1989).
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 9667-9671
-
-
Priestle, J.P.1
Schar, H.P.2
Grutter, M.G.3
-
52
-
-
14244272868
-
PHENIX: Building new software for automated crystallographic structure determination
-
Adams, P.D. et al. PHENIX: building new software for automated crystallographic structure determination. Acta Crystallogr. D Biol. Crystallogr. 58, 1948-1954 (2002).
-
(2002)
Acta Crystallogr. D Biol. Crystallogr.
, vol.58
, pp. 1948-1954
-
-
Adams, P.D.1
-
54
-
-
37049014272
-
Version 1.2 of the Crystallography and NMR system
-
Brunger, A.T. Version 1.2 of the Crystallography and NMR system. Nat. Protocols 2, 2728-2733 (2007).
-
(2007)
Nat. Protocols
, vol.2
, pp. 2728-2733
-
-
Brunger, A.T.1
|