Expression, purification and structural analysis of human IL-18 binding protein: A potent therapeutic molecule for allergy

Allergology International

Volumn 57, Issue 4, 2008, Pages 367-376

  Kimura, Takeshi ^a,b   Kato, Zenichiro ^a   Ohnishi, Hidenori ^a   Tochio, Hidehito ^b,c   Shirakawa, Masahiro ^b,c   Kondo, Naomi ^a  

^a GIFU UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Baculovirus; Binding mode; IL 18 binding protein; Purification; Structure

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 18; INTERLEUKIN 18 BINDING PROTEIN; INTERLEUKIN 18 RECEPTOR ALPHA; LIPOPOLYSACCHARIDE; RECOMBINANT HUMAN INTERLEUKIN 18 BINDING PROTEIN; RECOMBINANT INTERLEUKIN 18; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

ALLERGY; ANIMAL CELL; ARTICLE; BACULOVIRUS EXPRESSION SYSTEM; BINDING AFFINITY; BINDING COMPETITION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG PROTEIN BINDING; DRUG TARGETING; HUMAN; INHIBITION KINETICS; INSECT CELL; MONOCYTE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS INHIBITION; RECEPTOR UPREGULATION; STOICHIOMETRY; STRUCTURE ANALYSIS; SURFACE PLASMON RESONANCE;

EID: 58549111286     PISSN: 13238930     EISSN: 14401592     Source Type: Journal    
DOI: 10.2332/allergolint.O-08-546     Document Type: Article

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