Quorum quenching mediated approaches for control of membrane biofouling

International Journal of Biological Sciences

Volumn 10, Issue 5, 2014, Pages 547-562

  Lade, Harshad ^a   Paul, Diby ^a   Kweon, Ji Hyang ^a  

^a Konkuk University   (South Korea)

Author keywords

Biofouling; Membrane bioreactor; Natural compounds; Quorum quenching; Quorum sensing inhibition; Wastewater treatment

Indexed keywords

ARTIFICIAL MEMBRANE; BACTERIAL PROTEIN;

ARTIFICIAL MEMBRANE; BIOFOULING; BIOREACTOR; CHEMICAL STRUCTURE; CHEMISTRY; DEVICES; FILTRATION; METABOLISM; PHYSIOLOGY; PREVENTION AND CONTROL; QUORUM SENSING; SEWAGE; WATER MANAGEMENT;

BACTERIAL PROTEINS; BIOFOULING; BIOREACTORS; FILTRATION; MEMBRANES, ARTIFICIAL; MOLECULAR STRUCTURE; QUORUM SENSING; WASTE DISPOSAL, FLUID; WATER PURIFICATION;

EID: 84900830565     PISSN: 14492288     EISSN: None     Source Type: Journal    
DOI: 10.7150/ijbs.9028     Document Type: Review

References (225)

1. Drews A. Membrane fouling in membrane bioreactors-Characterisation, contradictions, cause and cures. J Memb Sci. 2010; 363: 1-28.
2. Judd S. Principles and applications of membrane bioreactors in water and wastewater treatment. In: 2nd ed. The MBR Book. Elsevier Ltd., UK; 2006.
3. Lesjean B, Tazi-Pain A, Thaure D, et al. Ten persistent myths and the realities of membrane bioreactor technology for municipal applications. Water Sci Technol. 2011; 63: 32-39.
4. Zheng X, Zhou Y, Chen S, et al. Survey of MBR market: Trends and perspec-tives in China. Desalination 2010; 250: 609-612.
5. Le-Clech P. Membrane bioreactors and their uses in wastewater treatments. Appl Microbiol Biotechnol. 2010; 88: 1253-1260.
6. Le-Clech P, Chen V, Fane TAG. Fouling in membrane bioreactors used in wastewater treatment. J Membr Sci. 2006; 284: 17-53.
7. Ramesh A, Lee DJ, Wang ML, et al. Biofouling in membrane bioreactor. Sep Sci Technol. 2006; 41: 1345-1370
8. Hook AL, Chang CY, Yang J, et al. Combinatorial discovery of polymers resistant to bacterial attachment. Nat Biotech. 2012; 30: 868-875.
9. Davies D. Understanding biofilm resistance to antibacterial agents. Nat Rev Drug Discov. 2003; 2: 114-122.
10. Dobretsov S, Teplitski M, Paul V. Mini-review: quorum sensing in the marine environment and its relationship to biofouling. Biofouling 2009; 25: 413-427.
11. Sauer K, Camper AK, Ehrlich GD, et al. Pseudomonas aeruginosa displays multiple phenotypes during development as a biofilm. J Bacteriol 2002; 184: 1140-1154.
12. Williams P. Quorum sensing: an emerging target for antibacterial chemo-therapy? Expert Opin Ther Targets. 2002; 6: 257-274.
13. Bjarnsholt T, Givskov M. Quorum sensing inhibitory drugs as next generation antimicrobials: worth the effort? Curr Infect Dis Rep. 2008; 10: 22-28.
14. Lowery CA, Salzameda NT, Sawada D, et al. Medicinal chemistry as a conduit for the modulation of quorum sensing. J Med Chem. 2010; 53: 7467-7489.
15. Uroz S, Dessaux Y, Oger P. Quorum sensing and quorum quenching: the yin and yang of bacterial communication. ChemBioChem 2009; 10: 205-216.
16. Ponnusamy K, Paul D, Kweon JH. Inhibition of quorum sensing mechanism and Aeromonas hydrophila biofilm formation by vanillin. Environ Eng Sci. 2009; 26: 1359-1363.
17. Eberl L, Molin S, Givskov M. Surface motility of Serratia liquefaciens MG1. J Bacteriol. 1999; 181: 1703-1712.
18. Truchado P, Giménez-Bastida JA, Larrosa M, et al. Inhibition of quorum sensing (QS) in Yersinia enterocolitica by an orange extract rich in glycosylated flavanones. J Agric Food Chem. 2012; 60: 8885-8894.
19. Rudrappa T, Bais HP. Curcumin, a known phenolic from Curcuma longa, attenuates the virulence of Pseudomonas aeruginosa PAO1 in whole plant and animal pathogenicity models. J Agric Food Chem. 2008; 56: 1955-1962.
20. Paul D, Kim YS, Ponnusamy K, et al. Application of quorum quenching to inhibit biofilm formation. Environ Eng Sci. 2009; 26: 1319-1324.
21. Oh HS, Yeon KM, Yang CS, et al. Control of membrane biofouling in MBR for wastewater treatment by quorum quenching bacteria encapsulated in mi-croporous membrane. Environ Sci Technol. 2012; 46: 4877-4884.
22. Kim SR, Oh HS, Jo SJ, et al. Biofouling control with bead-entrapped quorum quenching bacteria in membrane bioreactors: Physical and biological effects. Environ Sci Technol. 2013; 47: 836-842.
23. Choudhary S, Schmidt-Dannert C. Applications of quorum sensing in biotechnology. Appl Microbiol Biotechnol. 2010; 86: 1267-1279.
24. Waters CM, Bassler BL. Quorum sensing: cell-to-cell communication in bacteria. Ann Rev Cell Dev Biol. 2005; 21: 319-346.
25. Reading NC, Sperandio V. Quorum sensing: the many languages of bacteria. FEMS Microbiol Lett. 2006; 254: 1-11.
26. Chhabra S, Philipp B, Eberl L, et al. Extracellular communication in bacteria. In: Schulz S, ed. The chemistry of pheromones and other semiochemicals II. Vol 240: Springer Berlin Heidelberg; 2005: 279-315.
27. Williams P. Quorum sensing, communication and cross-kingdom signalling in the bacterial world. Microbiology 2007; 153: 3923-3938.
28. Yarwood JM, Bartels DJ, Volper EM, et al. Quorum sensing in Staphylococcus aureus biofilms. J Bacteriol. 2004; 186: 1838-1850.
29. George EA, Muir TW. Molecular mechanisms of agr quorum sensing in virulent staphylococci. Chembiochem 2007; 8: 847-855.
30. Engebrecht J, Nealson K, Silverman M. Bacterial bioluminescence: Isolation and genetic analysis of functions from Vibrio fischeri. Cell 1983; 32: 773-781.
31. McClean KH, Winson MK, Fish L, et al. Quorum sensing and Chromobacte-rium violaceum: exploitation of violacein production and inhibition for the detection of N-acylhomoserine lactones. Microbiology 1997; 143: 3703-3711.
32. Karlsson T, Turkina MV, Yakymenko O, et al. The Pseudomonas eruginosa N-acylhomoserine lactone quorum sensing molecules target IQGAP1 and modulate epithelial cell migration. PLoS Pathog. 2012; 8: e1002953.
33. Sio CF, Otten LG, Cool RH, et al. Quorum quenching by an N-acyl-homoserine lactone acylase from Pseudomonas aeruginosa PAO1. Infect Immun. 2006; 74: 1673-1682.
34. Shaw PD, Ping G, Daly SL, et al. Detecting and characterizing N-acyl-homoserine lactone signal molecules by thin-layer chromatography. Proc Natl Acad Sci USA 1997; 94: 6036-6041.
35. Swift S, Karlyshev AV, Fish L, et al. Quorum sensing in Aeromonas hydrophila and Aeromonas salmonicida: identification of the LuxRI homologs AhyRI and AsaRI and their cognate N-acylhomoserine lactone signal molecules. J Bacteriol. 1997; 179: 5271-5281.
36. Chen X, Schauder S, Potier N, et al. Structural identification of a bacterial quorum-sensing signal containing boron. Nature 2002; 415: 545-549.
37. Wood TK. Insights on Escherichia coli biofilm formation and inhibition from whole-transcriptome profiling. Environ Microbiol. 2009; 11: 1-15.
38. Sperandio V, Torres AG, Giron JA, et al. Quorum sensing is a global regula-tory mechanism in enterohemorrhagic Escherichia coli O157:H7. J Bacteriol. 2001; 183: 5187-5197.
39. Gelhaus HC, Rozak DA, Nierman WC, et al. Exogenous Yersinia pestis quorum sensing molecules N-octanoyl-homoserine lactone and N-(3-oxooctanoyl)-homoserine lactone regulate the LcrV virulence factor. Microb Pathog. 2009; 46: 283-287.
40. Miller ST, Xavier KB, Campagna SR, et al. Salmonella typhimurium recognizes a chemically distinct form of the bacterial quorum-sensing signal AI-2. Mol Cell 2004; 15: 677-687.
41. Choi J, Shin D, Ryu S. Implication of quorum sensing in Salmonella enterica serovar typhimurium virulence: The luxS gene is necessary for expression of genes in pathogenicity island 1. Infect Immun. 2007; 75: 4885-4890.
42. Degrassi G, Aguilar C, Bosco M, et al. Plant growth promoting Pseudomonas putida WCS358 produces and secretes four cyclic dipeptides: cross-talk with quorum sensing bacterial sensors. Curr Microbiol. 2002; 45: 250-254.
43. Holden MTG, Chhabra SR, de Nys R, et al. Quorum sensing cross talk: isolation and chemical characterization of cyclic dipeptides from Pseudomonas aeruginosa and other Gram-negative bacteria. Mol Microbiol. 1999; 33: 1254-1266.
44. Mashburn LM, Whiteley M. Membrane vesicles traffic signals and facilitate group activities in a prokaryote. Nature 2005; 437: 422-425.
45. Deziel E, Lepine F, Milot S, et al. Analysis of Pseudomonas aeruginosa 4-hydroxy-2-alkylquinolines (HAQs) reveals a role for 4-hydroxy-2-heptylquinoline in cell-to-cell communication. Proc Natl Acad Sci USA 2004; 101: 1339-1344.
46. Lepine F, Milot S, Deziel E, et al. Electrospray/mass spectrometric identification and analysis of 4-hydroxy-2-alkylquinolines (HAQs) produced by Pseudomonas aeruginosa. J Am Soc Mass Spectrom. 2004; 15: 862-869.
47. Wang LH, He Y, Gao Y, et al. A bacterial cell-cell communication signal with cross-kingdom structural analogues. Mol Microbiol. 2004; 51: 903-912.
48. Sturme MHJ, Kleerebezem M, Nakayama J, et al. Cell to cell communication by autoinducing peptides in gram-positive bacteria. Antonie Van Leeu-wenhoek 2002; 81: 233-243.
49. Malone CL, Boles BR, Horswill AR. Biosynthesis of Staphylococcus aure-us autoinducing peptides by using the Synechocystis DnaB mini-intein. Appl Environ Microbiol. 2007; 73: 6036-6044.
50. Ji G, Beavis RC, Novick RP. Cell density control of staphylococcal virulence mediated by an octapeptide pheromone. Proc Natl Acad Sci USA 1995; 92: 12055-12059.
51. Kleerebezem M, Quadri LE. Peptide pheromone-dependent regulation of antimicrobial peptide production in Gram-positive bacteria: A case of multicellular behavior. Peptides 2001; 22: 1579-1596.
52. Hamoen LW, Venema G, Kuipers OP. Controlling competence in Bacillus subtilis: shared use of regulators. Microbiology 2003; 149: 9-17.
53. Ansaldi M, Marolt D, Stebe T, et al. Specific activation of the Bacillus quor-um-sensing systems by isoprenylated pheromonevariants. Mol Microbiol. 2002; 44: 1561-1573.
54. Rutherford ST, Bassler BL. Bacterial quorum sensing: Its role in virulence and possibilities for its control. Cold Spring Harbor Perspect Med. 2012; 2: a012427.
55. Havarstein LS, Coomaraswamy G, Morrison DA. An unmodified heptade-capeptide pheromone induces competence for genetic transformation in Streptococcus pneumoniae. Proc Natl Acad Sci USA 1995; 92: 11140-11144.
56. Kleerebezem M, Quadri LEN, Kuipers OP, et al. Quorum sensing by peptide pheromones and two component signal transduction systems in Gram-positive bacteria. Mol Microbiol. 1997; 24: 895-904.
57. Xu H., Liu Y. Control and cleaning of membrane biofouling by energy un-coupling and cellular communication. Environ Sci Technol. 2011; 45: 595-601.
58. Juhas M, Eberl L, Tummler B. Quorum sensing: the power of cooperation in the world of Pseudomonas. Environ Microbiol. 2005; 7: 459-471.
59. Duan K, Surette MG. Environmental regulation of Pseudomonas aeruginosa PAO1 Las and Rhl quorum-sensing systems. J Bacteriol. 2007; 189: 4287-4236.
60. Shrout JD, Nerenberg R. Monitoring bacterial twitter: does quorum sensing determine the behavior of water and wastewater treatment biofilms? Environ Sci Technol. 2012; 46: 1995-2005.
61. Hentzer M, Givskov M, Eberl L. Quorum sensing in biofilms: Gossip in slime city. In: O'Toole MGaG, ed. Microbial Biofilms: ASM press, Washington DC; 2004: 118-140.
62. Nadell CD, Xavier JB, Levin SA, et al. The evolution of quorum sensing in bacterial biofilms. PLoS Biol. 2008;6(e):14.
63. Hammer B, Bassler B. Quorum sensing controls biofilm formation in Vibrio cholerae. Mol Microbiol. 2003; 50: 101-104.
64. Peter SM. A network of networks: quorum-sensing gene regulation in Pseu-domonas aeruginosa. Int J Med Microbiol. 2006; 296: 73-81.
65. Grossman AD. Genetic networks controlling the initiation of sporulation and the development of genetic competence in Bacillus subtilis. Annu Rev Genet. 1995; 29: 477-508.
66. Parsek MR, Greenberg EP. Sociomicrobiology: the connections between quorum sensing and biofilms. Trends Microbiol. 2005; 13: 27-33.
67. Winson MK, Swift S, Fish L, et al. Construction and analysis of luxCDABE-based plasmid sensors for investigating N-acyl homoserine lac-tone-mediated quorum sensing. FEMS Microbiol Lett. 1998; 163: 185-192.
68. Andersen JB, Heydorn A, Hentzer M, et al. gfp-based N-acyl homoser-ine-lactone sensor systems for detection of bacterial communication. Appl Environ Microbiol. 2001; 67: 575-585.
69. de Kievit TR, Iglewski BH. Bacterial quorum sensing in pathogenic relation-ships. Infect. Immun. 2000; 68: 4839-4849.
70. Lithgow JK, Wilkinson A, Hardman A, et al. The regulatory locus cinRI in Rhizobium leguminosarum controls a network of quorum-sensing loci. Mol Microbiol. 2000; 37: 81-97.
71. Horng YT, Deng SC, Daykin M, et al. The LuxR family protein SpnR functions as a negative regulator of N-acylhomoserine lactone-dependent quorum sensing in Serratia marcescens. Mol Microbiol. 2002; 45: 1655-1671.
72. Bassler BL, Losick R. Bacterially speaking. Cell 2006; 125: 237-246.
73. Davey ME, O'Toole GA. Microbial biofilms: from ecology to molecular genetics. Microbiol Mol Biol Rev. 2000; 64: 847-867.
74. Hall-Stoodley L, Costerton JW, Stoodley P. Bacterial biofilms: from the natural environment to infectious diseases. Nat Rev Microbiol. 2004; 2: 95-108.
75. Kaufmann GF, Park J, Janda KD. Bacterial quorum sensing: a new target for anti-infective immunotherapy. Expert Opin Biol Ther. 2008; 8: 719-724.
76. Costerton JW, Lewandowski Z, Caldwell DE, et al. Microbial biofilms. Annu Rev Microbiol. 1995; 49: 711-45.
77. O'Toole G, Kaplan HD, Kolter R. Biofilm formation as microbial development. Annu Rev Microbiol. 2000; 54: 81-127.
78. Greenberg EP. Bacterial communication and group behavior. J Clin Invest. 2003; 112: 1288-1290.
79. Yarwood JM, Schlievert PM. Quorum sensing in Staphylococcus infections. J Clinic Investig. 2003; 112: 1620-1625.
80. Adav SS, Lee DJ, Show KY, et al. Aerobic granular sludge: Recent advances. Biotechnol Adv. 2008; 26: 411-423.
81. Amy G. Fundamental understanding of organic matter fouling of membranes. Desalination 2008; 231: 44-51.
82. Kim HW, Oh HS, Kim SR, et al. Microbial population dynamics and prote-omics in membrane bioreactors with enzymatic quorum quenching. Appl Microbiol Biotechnol. 2013; 97: 4665-4675.
83. Bae TH, Tak TM. Interpretation of fouling characteristics of ultrafiltration membranes during the filtration of membrane bioreactror mixed liquor. J Membr Sci. 2005; 264: 151-160.
84. Defrance L, Jaffrin MY, Gupta B, et al. Contribution of various constituents of activated sludge to membrane bioreactor fouling. Bioresour Technol. 2000; 73: 105-112.
85. Davies DG, Parsek MR, Pearson JP, et al. The involvement of cell-to-cell signals in the development of a bacterial biofilm. Science 1998; 280: 295-298.
86. Ya-Wen H, Lian-Hui Z. Quorum sensing and virulence regulation in Xan-thomonas campestris. FEMS Microbiol Rev. 2008; 32: 842-857.
87. Toyofuku M, Nomura N, Kuno E, et al. Influence of the Pseudomonas quinolone signal on denitrification in Pseudomonas aeruginosa. J Bacteriol. 2008; 190: 7947-7956.
88. Lynch MJ, Swift S, Kirke DF, et al. The regulation of biofilm development by quorum sensing in Aeromonas hydrophila. Environ Microbiol. 2002; 4: 18-28.
89. Kim M, Lee S, Park HD, et al. Biofouling control by quorum sensing inhibition and its dependence on membrane surface. Water Sci Technol. 2012; 66: 1424-1430.
90. Xia S, Zhou L, Zhang Z, et al. Influence and mechanism of N-(3-oxooxtanoyl)-L-homoserine lactone (C8-oxo-HSL) on biofilm behaviors at the early stage. J Environ Sci. 2012; 24: 2035-2040.
91. Lade H, Paul D, Kweon JH. Isolation and molecular characterization of biofouling bacteria and profiling of quorum sensing signal molecules from membrane bioreactor activated sludge. Int J Mol Sci. 2014; 15: 2255-2273.
92. Lim SY, Kim S, Yeon KM, et al. Correlation between microbial community structure and biofouling in a laboratory scale membrane bioreactor with synthetic wastewater. Desalination 2012; 287: 209-215.
93. Yeon KM, Cheong WS, Oh HS, et al. Quorum sensing: A new biofouling control paradigm in a membrane bioreactor for advanced wastewater treatment. Environ Sci Technol. 2009; 43: 380-385.
94. Dong YH, Wang LH, Zhang LH. Quorum-quenching microbial infections: mechanisms and implications. Philos Trans R Soc Lond B Biol Sci. 2007; 362: 1201-1211.
95. Dobretsov S, Teplitski M, Bayer M, et al. Inhibition of marine biofouling by bacterial quorum sensing inhibitors. Biofouling 2011; 27: 893-905.
96. Hentzer M, Givskov M, Parsek MR. Targeting quorum sensing for treatment of chronic bacterial biofilm infections. Lab Med. 2002; 33: 295-306.
97. Geske GD, O'Neill JC, Blackwell HE. Expanding dialogues: From natural autoinducers to non-natural analogues that modulate quorum sensing in Gram-negative bacteria. Chem. Soc Rev. 2008; 37: 1432-1447.
98. Parveen N, Cornell KA. Methylthioadenosine/S-adenosylhomocysteine nucleosidase, a critical enzyme for bacterial metabolism. Mol Microbiol. 2011; 79: 7-20.
99. Lin YH, Xu JL, Hu JY, et al. Acyl-homoserine lactone acylase from Ralstonia strain XJ12B represents a novel and potent class of quorum-quenching en-zymes. Mol Microbiol. 2003; 47: 849-860.
100. Yates EA, Philipp B, Buckley C, et al. N-acylhomoserine lactones undergo lactonolysis in a pH-, temperature-, and acyl chain length-dependent manner during growth of Yersinia pseudotuberculosis and Pseudomonas aeruginosa. Infect Immun. 2002; 70: 5635-5646.
101. Koch B, Liljefors T, Persson T, et al. The LuxR receptor: The sites of interaction with quorum-sensing signals and inhibitors. Microbiology 2005; 151: 3589-3602.
102. Chen G, Swern LR, Swern DL, et al. A strategy for antagonizing quorum sensing. Mol Cell 2011; 42: 199-209.
103. Vanderkooi OG, Low DE, Green K, et al. Predicting antimicrobial resistance in invasive pneumococcal infections. Clin Infect Dis. 2005; 40: 1288-1297.
104. Kubo I, Masuoka N, Ha TJ, et al. Antioxidant activity of anacardic acids. Food Chem. 2006; 99: 555-562.
105. Bauer WD, Mathesius U. Plant responses to bacterial quorum sensing signals. Curr Opin Plant Biol. 2004; 7: 429-433.
106. Dudler R, Eberl E. Interactions between bacteria and eukaryotes via small molecules. Curr Opin Biotechnol. 2006; 17: 268-273.
107. Teplitski M, Mathesius U, Rambaugh KP. Perception and degradation of N-acyl homoserine lactone quorum sensing signals by mammalian and plant cells. Chem Rev. 2011; 111: 100-116.
108. Vattem DA, Mihalik K, Crixell SH, et al. Dietary phytochemicals as quorum sensing inhibitors. Fitoterapia 2007; 78: 302-310.
109. Ponnusamy K, Paul D, Kim YS, et al. 2(5H)-Furanone: A Prospective strategy for biofouling-control in membrane biofilm bacteria by quorum sensing inhibition. Braz J Microbiol. 2010; 41: 227-234.
110. Manefield M, Rasmussen TB, Henzter M, et al. Halogenated furanones inhibit quorum sensing through accelerated LuxR turnover. Microbiology 2002; 148: 1119-1127.
111. Defoirdt T, Miyamoto CM, Wood TK, et al. The natural furanone (5Z)-4-bromo-5-(bromomethylene)-3-butyl-2(5H)-furanone disrupts quorum sensing-regulated gene expression in Vibrio harveyi by decreasing the DNA-binding activity of the transcriptional regulator protein luxR. Environ Microbiol. 2007; 9: 2486-2495.
112. Ren D, Sims JJ, Wood TK. Inhibition of biofilm formation and swarming of Escherichia coli by (5Z)-4-bromo-5-(bromomethylene)-3-butyl-2(5H)-furanone. Environ Microbiol. 2001; 3: 731-736.
113. Bjarnsholt T, Jensen PO, Rasmussen TB, et al. Garlic blocks quorum sensing and promotes rapid clearing of pulmonary Pseudomonas aeruginosa infec-tions. Microbiology 2005; 151: 3873-3880.
114. Jakobsen TH, van Gennip M, Phipps RK, et al. Ajoene, a sulfur-rich molecule from garlic, inhibits genes controlled by quorum sensing. Antimicrob Agents Chemother. 2012; 56: 2314-2325.
115. Jakobsen TH, Bragason SK, Phipps RK, et al. Food as a source for quorum sensing inhibitors: iberin from horseradish revealed as a quorum sensing in-hibitor of Pseudomonas aeruginosa. Appl Environ Microbiol. 2012; 78: 2410-2421.
116. Ganin, H, Rayo J, Amara N, et al. Sulforaphane and erucin, natural isothio-cyanates from broccoli, inhibit, bacterial quorum sensing. Med Chem Com-mun. 2013; 4: 175-179.
117. Vandeputte OM, Kiendrebeogo M, Rasamiravaka T, et al. The flavanone naringenin reduces the production of quorum sensing-controlled virulence factors in Pseudomonas aeruginosa PAO1. Microbiology 2011; 157: 2120-2132.
118. Vandeputte OM, Kiendrebeogo M, Rajaonson S, et al. Identification of catechin as one of the flavonoids from Combretum albiflorum bark extract that reduces the production of quorum-sensing-controlled virulence factors in Pseudomonas aeruginosa PAO1. Appl Environ Microbiol. 2010; 76: 243-253.
119. Annapoorani A, Umamageswaran V, Parameswari R, et al. Computational discovery of putative quorum sensing inhibitors against LasR and RhlR re-ceptor proteins of Pseudomonas aeruginosa. J Comput Aided Mol Des. 2012; 26: 1067-1077.
120. Annapoorani A, Parameswari R, Pandian SK, et al. Methods to determine antipathogenic potential of phenolic and flavonoid compounds against uri-nary pathogen Serratia marcescens. J Microbiol Methods 2012; 91: 208-211.
121. Rasmussen TB, Bjarnsholt T, Skindersoe ME, et al. Screening for quor-um-sensing inhibitors (QSI) by use of a novel genetic system, the QSI selector. J Bacteriol. 2005; 187: 1799-1814.
122. Givskov M, de Nys R, Manefield M, et al. Eukaryotic interference with homo-serine lactone mediated prokaryotic signaling. J Bacteriol. 1996; 178: 6618-6622.
123. Choo JH, Rukayadi Y, Hwang JK. Inhibition of bacterial quorum sensing by vanilla extract. Lett Appl Microbiol. 2006; 42: 637-641.
124. Oger P, Farrand SK. Co-evolution of the agrocinopine opines and the agro-cinopine-mediated control of TraR, the quorum-sensing activator of the Ti plasmid conjugation system. Mol Microbiol. 2001; 41: 1173-1185.
125. Keshavan ND, Chowdhary PK, Haines DC, et al. L-canavanine made by Medicao sativa interferes with quorum sensing in Sinorhizobium meliloti. J Bacteriol. 2005; 187: 8427-8436.
126. Chevrot R, Rosen R, Haudecoeur E, et al. GABA controls the level of quor-um-sensing signal in Agrobacterium tumefaciens. Proc Natl Acad Sci USA 2006; 103: 7460-7464.
127. Bouche N, Lacombe B, Fromm H. GABA signaling: a conserved and ubiqui-tous mechanism. Trends Cell Biol. 2003; 13: 607-610.
128. Walker TS, Bais HP, Deziel E, et al. Pseudomonas aeruginosa-plant root interactions, pathogenicity, biofilm formation, and root exudation. Plant Physiol. 2004; 34: 320-331.
129. Yuan ZC, Edlind MP, Liu P, et al. The plant signal salicylic acid shuts down expression of the vir regulon and activates quormone-quenching genes in Agrobacterium. Proc Natl Acad Sci USA 2007; 104: 11790-11795.
130. Singh BN, Singh BR, Singh RL, et al. Oxidative DNA damage protective activity, antioxidant and anti-quorum sensing potentials of Moringa oleifera. Food Chem Toxicol. 2009; 47: 1109-1116.
131. Cady NC, McKean KA, Behnke J, et al. Inhibition of biofilm bormation, quorum sensing and infection in Pseudomonas aeruginosa by natural prod-ucts-inspired organosulfur compounds. PLoS ONE 2012; 7: e38492.
132. Ren D, Zuo R, González-Barrios AF, et al. Differential gene expression for investigation of Escherichia coli biofilm inhibition by plant extract ursolic acid. Appl Environ Microbiol. 2005; 71: 4022-4034.
133. Liu J. Pharmacology of oleanolic acid and ursolic acid. J Ethanopharmacol 1995; 49: 57-68.
134. Sarabhai S, Sharma P, Capalash N. Ellagic acid derivatives from Terminalia chebula Retz. downregulate the expression of quorum sensing genes to at-tenuate Pseudomonas aeruginosa PAO1 virulence. PLoS One 2013; 8: e53441.
135. Huber B, Eberl L, Feucht W, et al. Influence of polyphenols on bacterial biofilm formation and quorum sensing. Z Naturforsch C. 2003; 58: 879-884.
136. Chai Y, Tsai CS, Cho H, et al. Reconstitution of the biochemical activties of the AttJ repressor and the AttK, Atl and AttM catabolic enzymes of Agrobacterium tumefaciens. J Bacteriol. 2007; 189: 3674-3679.
137. Akiyama H, Fujii K, Yamasaki O, et al. Antibacterial action of several tannins against Staphylococcus aureus. J Antimicrob Chemother. 2001; 48: 487-491.
138. Blanco AR, Sudano-Roccaro A, Spoto GC, et al. Epigallocatechin gallate inhibits biofilm formation by ocular Staphylococcal isolates. Antimicrob Agents Chemother. 2005; 49: 4339-4343.
139. Zhao WH, Hu ZQ, Hara Y, et al. Inhibition by epigallocatechin gallate (EGCg) of conjugative R plasmid transfer in Escherichia coli. J Infect Chemother. 2001; 7: 195-197.
140. Ni N, Choudhary G, Li M, et al. Pyrogallol and its analogs can antagonize bacterial quorum sensing in Vibrio harveyi. Bioorg Med Chem Lett. 2008; 18: 1567-1572.
141. Sangeetha J, Vijayalakshmi K. Determination of bioactive components of ethyl acetate fraction of Punica granatum rind extract. Int J Pharm Sci Drug Res. 2011; 3: 116-122.
142. Brackman G, Defoirdt T, Miyamoto C, et al. Cinnamaldehyde and cinnamaldehyde derivatives reduce virulence in Vibrio spp. by decreasing the DNA-binding activity of the quorum sensing response regulator LuxR. BMC Microbiol. 2008; 8: 149-162.
143. Niu C, Afre S, Gilbert ES. Sub-inhibitory concentrations of cinnamaldehyde interfere with quorum sensing. Lett Appl Microbiol. 2006; 43: 489-494.
144. Girennavar B, Cepeda ML, Soni KA, et al. Grapefruit juice and its furocoumarins inhibits autoinducer signaling and biofilm formation in bacteria. Int J Food Microbiol. 2008; 125: 204-208.
145. Zahin M, Hasan S, Aqil F, et al. Screening of certain medicinal plants from India for their anti-quorum sensing activity. Indian J Exp Biol. 2010; 48: 1219-1224.
146. Giménez-Bastida JA, Truchado P, Larrosa M, et al. Urolithins, ellagitannin metabolites produced by colon microbiota, inhibit quorum sensing in Yersinia enterocolitica: Phenotypic response and associated molecular changes. Food Chem. 2012; 132: 1465-1474.
147. O'May CO, Tufenkji N. Pseudomonas aeruginosa swarming motility is blocked by cranberry proanthocyanidins and other tannin-containing materials. Appl Environ Microbiol. 2011; 77: 3061-3067.
148. Packiavathy IA, Priya S, Pandian SK, et al. Inhibition of biofilm development of uropathogens by curcumin-an anti-quorum sensing agent from Curcuma longa. Food Chem. 2014; 148: 453-460.
149. Kim JS, Kim YH, Seo YW, et al. Quorum sensing inhibitors from the red alga, Ahnfeltiopsis flabelliformis. Biotechnol Bioproc Eng. 2007; 12: 308-311.
150. Musthafa KS, Ravi AV, Annapoorani A, et al. Evaluation of an-ti-quorum-sensing activity of edible plants and fruits through inhibition of the N-acyl-homoserine lactone system in Chromobacterium violaceum and Pseudomonas aeruginosa. Chemotherapy 2010; 56: 333-339.
151. Siddiqui MF, Sakinah M, Ismail AF, et al. The anti-biofouling effect of Piper betle extract against Pseudomonas aeruginosa and bacterial consortium. Desalination 2012; 288: 24-30.
152. Packiavathy IA, Agilandeswari P, Musthafa KS, et al. Antibiofilm and quorum sensing inhibitory potential of Cuminum cyminum and its secondary metabolite methyl eugenol against Gram negative bacterial pathogens. Food Res Int. 2012; 45: 85-92.
153. Manefield M, de Nys R, Kumar N, et al. Evidence that halogenated furanones from Delisea pulchra inhibit acylated homoserine lactone (AHL)-mediated gene expression by displacing the AHL signal from its receptor protein. Mi-crobiology 1999; 145: 283-291.
154. Lowery CA, Dickerson TJ, Janda KD. Interspecies and interkingdom communication mediated by bacterial quorum sensing. Chem Soc Rev. 2008; 37: 1337-1346.
155. Maximilien R, de Nys R, Holmstrom C, et al. Chemical mediation of bacterial surface colonisation by secondary metabolites from the red alga Delisea pulchra. Aquat Microb Ecol. 1998; 15: 233-246.
156. Sanchez-Contreras M, Bauer WD, Gao M, et al. Quorum-sensing regulation in rhizobia and its role in symbiotic interactions with legumes. Philos Trans R Soc Lond B Biol Sci. 2007; 362: 1149-1163.
157. Eberhard A, Widrig CA, McBath P, et al. Analogs of the autoinducer of bioluminescence in Vibrio fischeri. Arch Microbiol. 1986; 146: 35-40.
158. Dong YH, Xu JL, Li XZ, et al. AiiA, an enzyme that inactivates the acylho-moserine lactone quorum-sensing signal and attenuates the virulence of Er-winia carotovora. Proc Natl Acad Sci USA 2000; 97: 3526-3531.
159. Hentzer M, Wu H, Andersen JB, et al. Attenuation of Pseudomonas aeru-ginosa virulence by quorum sensing inhibitors. EMBO J. 2003; 22: 3803-3815.
160. de Nys R, Givskov M, Kumar N, et al. Furanones. Prog Mol Subcell Biol. 2006; 42: 55-86.
161. Kalia VC. Quorum sensing inhibitors: An overview. Biotechnol Adv. 2013; 31: 224-245.
162. Truchado P, Tomás-Barberán FA, Larrosa M, et al. Food phytochemicals act as quorum sensing inhibitors reducing production and/or degrading autoinducers of Yersinia enterocolitica and Erwinia carotovora. Food Control 2012; 24: 78-85.
163. Vikram A, Jayaprakasha GK, Jesudhasan PR, et al. Suppression of bacterial cell-cell signaling, biofilm formation and type III secretion system by citrus flavonoids. J Appl Microbiol. 2010; 109: 515-527.
164. Amara N, Mashiach R, Amar D. Covalent inhibition of bacterial quorum sensing. J Am Chem Soc. 2009; 131: 10610-10619.
165. Rosenthal GA. L-Canavanine: a higher plant insecticidal allelochemical. Amino Acids 2001; 21: 319-330.
166. Teplitski M, Robinson JB, Bauer WD. Plants secrete substances that mimic bacterial N-acyl homoserine lactone signal activities and affect population density-dependent behaviors in associated bacteria. Mol Plant Microbe Interact. 2000; 13: 637-648.
167. Bosgelmez-Tinaz G, Ulusoy S, Ugur A, et al. Inhibition of quorum sens-ing-regulated behaviors by Scorzonera sandrasica. Curr Microbiol. 2007; 55: 114-118.
168. Adonizio AL, Downum K, Bennett BC, et al. Anti-quorum sensing activity of medicinal plants in southern Florida. J Ethnopharmacol 2006; 105: 427-435.
169. Persson T, Hansen TH, Rasmussen TB, et al. Rational design and synthesis of new quorum-sensing inhibitors derived from acylated homoserine lactones and natural products from garlic. Org Biomol Chem. 2005; 3: 253-262.
170. Vikram A, Jesudhasan PR, Jayaprakasha GK, et al. Citrus limonoids interfere with Vibrio harveyi cell-cell signaling and biofilm formation by modulating the response regulator LuxO. Microbiology 2011; 157: 99-110.
171. Persson T, Givskov M, Nielsen J. Quorum sensing inhibition: targeting chemical communication in Gram-negative bacteria. Curr Med Chem. 2005; 12: 3103-3115.
172. Lönn-Stensrud J, Petersen FC, Benneche T, et al. Synthetic bromated furanone inhibits autoinducer-2-mediated communication and biofilm formation in oral streptococci. Oral Microbiol Immunol. 2007; 22: 340-346.
173. Rasmussen TB, Givskov M. Quorum sensing inhibitors: a bargain of effects. Microbiology 2006; 152: 895-904.
174. Rasmussen TB, Givskov M. Quorum-sensing inhibitors as anti-pathogenic drugs. Int J Med Microbiol. 2006; 296: 149-161.
175. Ponnusamy K, Kappachery S, Thekeettle M, et al. Anti-biofouling property of vanillin on Aeromonas hydrophila initial biofilm on various membrane sur-faces. World J Microbiol Biotechnol. 2013; 29: 1695-1703.
176. Siddiqui MF, Singh L, Zularisam AW, et al. Biofouling mitigation using Piper betleextract in ultrafiltration MBR. Desalin Water Treat. 2013; 51: 6940-6951.
177. Siddiqui MF, Sakinah M, Singh L, et al. Targeting N-acyl-homoserine-lactones to mitigate membrane biofouling based on quorum sensing using a biofouling reducer. J Biotechnol. 2012; 161:190-197.
178. Dong YH, Wang LH, Xu JL, et al. Quenching quorum-sensing-dependent bacterial infection by an N-acyl homoserine lactonase. Nature 2001; 411: 813-817.
179. Zhang HB, Wang LH, Zhang LH. Genetic control of quorum-sensing signal turnover in Agrobacterium tumefaciens. Proc Natl Acad Sci USA 2002; 99: 4638-4643.
180. Leadbetter JR, Greenberg EP. Metabolism of acyl-homoserine lactone quor-um-sensing signals by Variovorax paradoxus. J Bacteriol. 2000; 182: 6921-6926.
181. Chowdhary PK, Keshavan N, Nguyen HQ, et al. Bacillus megaterium CYP102A1 oxidation of acyl homoserine lactones and acyl homoserines. Biochemistry 2007; 46: 14429-14437.
182. Uroz S, Chhabra SR, Cámara M, et al. N-acylhomoserine lactone quor-um-sensing molecules are modified and degraded by Rhodococcus erythropolis W2 by both amidolytic and novel oxidoreductase activities. Microbiology 2005; 151: 3313-3322.
183. Huang JJ, Han JI, Zhang LH, et al. Utilization of acyl-homoserine lactone quorum signals for growth by a soil pseudomonad and Pseudomonas aeruginosa PAO1. Appl Environ Microbiol. 2003; 69: 5941-5949.
184. Park SY, Kang HO, Jang HS, et al. Identification of extracellular N-acylhomoserine lactone acylase from a Streptomyces sp. and its application to quorum quenching. Appl Environ Microbiol. 2005; 71: 2632-2641.
185. Huang JJ, Petersen A, Whiteley M, et al. Identification of QuiP, the product of gene PA1032, as the second acyl-homoserine lactone acylase of Pseudomonas aeruginosa PAO1. Appl Environ Microbiol. 2006; 72: 1190-1197.
186. Romero M, Diggle SP, Heeb S, et al. Quorum quenching activity in Anabaena sp. PCC 7120: Identification of AiiC, a novel AHL-acylase. FEMS Microbiol Lett. 2008; 280: 73-80.
187. Shepherd RW, Lindow SE. Two dissimilar N-acyl-homoserine lactone acylases of Pseudomonas syringae influence colony and biofilm morphology. Appl Environ Microbiol. 2009; 75: 45-53.
188. Chan KG, Wong CS, Yin WF, et al. Rapid degradation of N-3-oxoacylhomoserine lactones by a Bacillus cereus isolate from Malaysian rainforest soil. Antonie Van Leeuwenhoek 2010; 98: 299-305.
189. Dong YH, Gusti AR, Zhang Q, et al. Identification of quorum-quenching N-acyl homoserine lactonases from Bacillus species. Appl Environ Microbiol. 2002; 68: 1754-1759.
190. Huma N, Shankar P, Kushwah J, et al. Diversity and polymorphism in AHL-lactonase gene (aiiA) of Bacillus. J Microbiol Biotechnol. 2011; 21: 1001-1011.
191. Liu D, Momb J, Thomas PW, et al. Mechanism of the quorum-quenching lactonase (AiiA) from Bacillus thuringiensis. 1. Product-bound structures. Biochemistry 2008; 47: 7706-7714.
192. Bentley SD, Chater KF, Cerdeno-Tarraga AM, et al. Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2). Nature 2002; 417: 141-147.
193. Liu D, Thomas PW, Momb J, et al. Structure and specificity of a quor-um-quenching lactonase (AiiB) from Agrobacterium tumefaciens. Biochemistry 2007; 46: 11789-11799.
194. Riaz K, Elmerich C, Moreira D, et al. A metagenomic analysis of soil bacteria extends the diversity of quorum-quenching lactonases. Environ Microbi-ol. 2008; 10: 560-70.
195. Mei GY, Yan XX, Turak A, et al. AidH, an alpha/beta-hydrolase fold family member from an Ochrobactrum sp. strain, is a novel N-acylhomoserine lac-tonase. Appl Environ Microbiol. 2010; 76: 4933-4942.
196. Ogawa K, Nakajima-Kambe T, Nakahara T, et al. Coimmobilization of gluconolactonase with glucose oxidase for improvement in kinetic property of enzymatically induced volume collapse in ionic gels. Biomacromolecules 2002; 3: 625-631.
197. Delalande L, Faure D, Raffoux A, et al. N-hexanoyl-L-homoserine lactone, a mediator of bacterial quorum-sensing regulation, exhibits plant-dependent stability and may be inactivated by germinating Lotus corniculatus seedlings. FEMS Microbiol Ecol. 2005; 52: 13-20.
198. Fatima Q, Zahin M, Khan MSA, et al. Modulation of quorum sensing con-trolled behavior of bacteria by growing seedling, seed and seedling extracts of leguminous plants. Ind J Microbiol. 2010; 50: 238-242.
199. Gotz C, Fekete A, Gebefuegi I, et al. Uptake, degradation and chiral discrimination of N-acyl-D/L-homoserine lactones by barley (Hordeum vulgare) and yam bean (Pachyrhizus erosus) plants. Anal Bioanal Chem. 2007; 389: 1447-1457.
200. Sauer K, Camper AK. Characterization of phenotypic changes in Pseudomonas putida in response to surface associated growth. J Bacteriol. 2001; 183: 6579-6589.
201. Xu F, Byun T, Deussen HJ, et al. Degradation of N-acylhomoserine lactones, the bacterial quorum sensing molecules, by acylase. J Biotechnol. 2003; 101: 89-96.
202. Jiang W, Xia S, Liang J, et al. Effect of quorum quenching on the reactor performance, biofouling and biomass characteristics in membrane bioreactors. Water Res. 2013; 47: 187-196.
203. Kim JH, Choi DC, Yeon KM, et al. Enzyme-immobilized nanofiltration membrane to mitigate biofouling based on quorum quenching. Environ Sci Technol. 2011; 45: 1601-1607.
204. Yeon KM, Lee CH, Kim J. Magnetic enzyme carrier for effective biofouling control in the membrane bioreactor based on enzymatic quorum quenching. Environ Sci Technol. 2009; 43: 7403-7409.
205. Chen CN, Chen CJ, Liao CT, et al. A probable aculeacin a acylase from the Ralstonia solanacearum GMI1000 is N-acyl-homoserine lactone acylase with quorum-quenching activity. BMC Microbiol. 2009; 9: 89.
206. Morohoshi T, Nakazawa S, Ebata A, et al. Identification and characterization of N-acylhomoserine lactone-acylase from the fish intestinal Shewanella sp. strain MIB015. Biosci Biotechnol Biochem. 2008; 72: 1887-1893.
207. Chan KG, Atkinson S, Mathee K, et al. Characterization of N-acylhomoserine lactone-degrading bacteria associated with the Zingiber officinale (ginger) rhizosphere: Co-existence of quorum quenching and quorum sensing in Acinetobacter and Burkholderia. BMC Microbiol. 2011; 11: 51.
208. Cheong WS, Lee CH, Moon YH, et al. Isolation and identification of indige-nous quorum quenching bacteria, Pesudomonas sp. 1A1, for biofouling control in MBR. Ind Eng Chem Res. 2013; 52: 10552-10560.
209. Chun CK, Ozer EA, Welsh MJ, et al. Inactivation of a Pseudomonas aeruginosa quorum-sensing signal by human airway epithelia. Proc Natl Acad Sci USA 2004; 101: 3587-3590.
210. Wopperer J, Cardona ST, Huber B, et al. A quorum-quenching approach to investigate the conservation of quorum-sensing-regulated functions within the Burkholderia cepacia complex. Appl Environ Microbiol. 2006; 72: 1579-1587.
211. Ulrich RL. Quorum quenching: enzymatic disruption of N-acylhomoserine lactone-mediated bacterial communication in Burkholderia thailandensis. Appl Environ Microbiol. 2004; 70: 6173-6180.
212. Lee SJ, Park SY, Lee JJ, et al. Genes encoding the N-acyl homoserine lac-tone-degrading enzyme are widespread in many subspecies of Bacillus thu-ringiensis. Appl Environ Microbiol. 2002; 68: 3919-3924.
213. Carlier A, Uroz S, Smadja B, et al. The Ti plasmid of Agrobacterium tumefaciens harbors an attM-paralogous gene, aiiB, also encoding N-acylhomoserine lactonase activity. Appl Environ Microbiol. 2003; 69: 4989-4993.
214. Chow JY, Xue B, Lee KH, et al. Directed evolution of a thermostable quor-um-quenching lactonase from the amidohydrolase superfamily. J Biol Chem. 2010; 285: 40911-40920.
215. Wang WZ, Morohoshi T, Ikenoya M, et al. AiiM, a novel class of N-acylhomoserine lactonase from the leaf-associated bacterium Microbacte-rium testaceum. Appl Environ Microbiol. 2010; 76: 2524-2530.
216. Chow JY, Wu L, Yew WS. Directed evolution of a quorum-quenching lacto-nase from Mycobacterium avium subsp. paratuberculosis K-10 in the ami-dohydrolase superfamily. Biochemistry 2009; 48: 4344-4353.
217. Afriat L, Roodveldt C, Manco G, et al. The latent promiscuity of newly identified microbial lactonases is linked to a recently diverged phosphotriesterase. Biochemistry 2006; 45: 13677-13686.
218. Morohoshi T, Tominaga Y, Someya N, et al. Complete genome sequence and characterization of the N-acylhomoserine lactone-degrading gene of the po-tato leaf-associated Solibacillus silvestris. J Biosci Bioeng. 2012; 113: 20-25.
219. Merone L, Mandrich L, Rossi M, et al. A thermostable phosphotriesterase from the archaeon Sulfolobus solfataricus: Cloning, overexpression and properties. Extremophiles 2005; 9: 297-305.
220. Elias M, Dupuy J, Merone L, et al. Structural basis for natural lactonase and promiscuous phosphotriesterase activities. J Mol Biol. 2008; 379: 1017-1028.
221. Uroz S, Oger PM, Chapelle E, et al. A Rhodococcus qsdA-encoded enzyme defines a novel class of large-spectrum quorum-quenching lactonases. Appl Environ Microbiol. 2008; 74: 1357-1366.
222. Park SY, Lee SJ, Oh TK, et al. AhlD, an N-acylhomoserine lactonase in Arthrobacter sp., and predicted homologues in other bacteria. Microbiology 2003; 149: 1541-1550.
223. Lee B, Yeon KM, Shim J, et al. Effective antifouling using quorum-quenching acylase stabilized in magnetically-separable mesoporous silica. Biomacro-molecules, 2014; 15: 1153-1159.
224. Basu S, Mehreja R, Thiberge S, et al. Spatiotemporal control of gene expression with pulse-generating networks. Proc Natl Acad Sci USA 2004; 101: 6355-6360.
225. Jahangir D, Oh HS, Kim SR, et al. Specific location of encapsulated quorum quenching bacteria for biofouling control in an external submerged membrane bioreactor. J Memb Sci. 2012; 411: 130-136.