Structural Basis for Natural Lactonase and Promiscuous Phosphotriesterase Activities

Journal of Molecular Biology

Volumn 379, Issue 5, 2008, Pages 1017-1028

  Elias, Mikael ^a,b   Dupuy, Jérôme ^c   Merone, Luigia ^d   Mandrich, Luigi ^d   Porzio, Elena ^d   Moniot, Sébastien ^a   Rochu, Daniel ^e   Lecomte, Claude ^a   Rossi, Mosè ^d   Masson, Patrick ^e   Manco, Giuseppe ^d   Chabriere, Eric ^a,b,e  

^a Nancy University CNRS   (France)

^b Centre National de la Recherche Scientifique   (France)

^c INSTITUT DE BIOLOGIE STRUCTURALE   (France)

^d INSTITUTE OF PROTEIN BIOCHEMISTRY   (Italy)

^e CENTRE DE RECHERCHES   (France)

Author keywords

3D structure; active site mutants; hyperthermophilic enzymes; lactonase; phosphotriesterase

Indexed keywords

GLUCONOLACTONASE; LACTONE; PHOSPHOTRIESTERASE;

ARTICLE; CATALYSIS; ENZYME ACTIVITY; HYDROLYSIS; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN STRUCTURE;

ARCHAEA; SULFOLOBUS SOLFATARICUS;

EID: 44449170433     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2008.04.022     Document Type: Article

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