The intestinal microbiota and probiotics

Probiotic Bacteria and Enteric Infections: Cytoprotection by Probiotic Bacteria

Volumn , Issue , 2011, Pages 41-63

  Forssten, Sofia D ^a   Lahtinen, Sampo J ^a   Ouwehand, Arthur C ^a  

^a Danisco Finland Oy   (Finland)

Author keywords

Bacterial composition; Gastrointestinal tract; Gut health microbiota; Probiotic

Indexed keywords

EID: 84900589632     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-94-007-0386-5_2     Document Type: Chapter

References (143)

1. Adlerberth I, Lindberg E, Aberg N, Hesselmar B, Saalman R, Strannegård I, Wold A (2010) Reduced enterobacterial and increased staphylococcal colonization of the infantile bowel: an effect of hygienic lifestyle? Pediatr Res 59(1):96-101
2. Ahrne S, Lonnermark E, Wold AE, Aberg N, Hesselmar B, Saalman R, Strannegard IL, Molin G, Adlerberth I (2005) Lactobacilli in the intestinal microbiota of Swedish infants. Microb Infect 7(11-12):1256-1262
3. Alander M, Korpela R, Saxelin M, Vilpponen-Salmela T, Mattila-Sandholm T, von Wright A (1997) Recovery of Lactobacillus rhamnosus GG from human colonic biopsies. Lett Appl Microbiol 24(5):361-364
4. Amor KB, Breeuwer P, Verbaarschot P, Rombouts FM, Akkermans AD, de Vos WM, Abee T (2002) Multiparametric flow cytometry and cell sorting for the assessment of viable, injured, and dead Bifidobacterium cells during bile salt stress. Appl Environ Microbiol 68(11):5209-5216
5. Asahara T, Takahashi M, Nomoto K, Takayama H, Onoue M, Morotomi M, Tanaka R, Yokokura T, Yamashita N (2003) Assessment of safety of Lactobacillus strains based on resistance to host innate defence mechanisms. Clin Diagn Lab Immunol 10(1):169-173
6. Bartosch S, Fite A, Macfarlane GT, McMurdo MET (2004) Characterization of bacterial communities in faeces from healthy elderly volunteers and hospitalized elderly patients by using realtime PCR and effects of antibiotic treatment on the faecal microbiota. Appl Environ Microbiol 70(6):3575-3581
7. Bevilacqua L, Ovidi M, Di Mattia E, Trovatelli LD, Canganella F (2003) Screening of Bifidobacterium strains isolated from human faeces for antagonistic activities against potentially bacterial pathogens. Microbiol Res 158(2):179-185
8. Boehm G, Stahl B, Jelinek J, Knol J, Miniello V, Moro GE (2005) Prebiotic carbohydrates in human milk and formulas. Acta Paediatr Suppl 94(449):18-21
9. Bovee-Oudenhoven IMJ, ten Bruggencate SJM, Lettink-Wissink MLG, van der Meer R (2003) Dietary fructo-oligosaccharides and lactulose inhibit intestinal colonisation but stimulate translocation of Salmonella in rats. Gut 52:1572-1578
10. Braat H, van den Brande J, van Tol E, Hommes D, Peppelenbosch M, van Deventer S (2004) Lactobacillus rhamnosus induces peripheral hyporesponsiveness in stimulated CD4+ T cells via modulation of dendritic cell function. Am J Clin Nutr 80(6):1618-1625
11. Burns AJ, Rowland IR (2004) Antigenotoxicity of probiotics and prebiotics on faecal water-induced DNA damage in human colon adenocarcinoma cells. Mutat Res 551(1-2):233-243
12. Canani RB, Cirillo P, Roggero P, Romano C, Malamisura B, Terrin G, Passariello A, Manguso F, Morelli L, Guarino A (2006) Therapy with gastric acidity inhibitors increases the risk of acute gastroenteritis and community-acquired pneumonia in children. Pediatrics 117(5):e817-e820
13. Chen JJ, Cai W, Feng Y (2007) Development of intestinal bifidobacteria and lactobacilli in breastfed neonates. Clin Nutr 26(5):559-566
14. Choi SS, Kim Y, Han KS, You S, Oh S, Kim SH (2006) Effects of Lactobacillus strains on cancer cell proliferation and oxidative stress in vitro. Lett Appl Microbiol 42(5):452-458
15. Collado MC, Meriluoto J, Salminen S (2007) Role of commercial probiotic strains against human pathogen adhesion to intestinal mucus. Lett Appl Microbiol 45(4):454-460
16. Daniel C, Poiret S, Goudercourt D, Dennin V, Leyer G, Pot B (2006) Selecting lactic acid bacteria for their safety and functionality by use of a mouse colitis model. Appl Environ Microbiol 72(9):5799-5805
17. de Vrese M, Schrezenmeir J (2008) Probiotics, prebiotics, and synbiotics. Adv Biochem Eng/Biotechnol 111:1-66
18. Dekker JW, Wickens KW, Black PN, Stanley TV, Mitchell EA, Fitzharris P, Tannock GW, Purdie G, Crane J (2009) Safety aspects of probiotic bacterial strains Lactobacillus rhamnosus HN001 and Bifidobacterium animalis subsp. lactis HN019 in human infants aged 0-2 years. Int Dairy J 19:149-154
19. Dobson AE, Sanozky-Dawes RB, Klaenhammer TR (2007) Identification of an operon and inducing peptide involved in the production of lactacin B by Lactobacillus acidophilus. J Appl Microbiol 103(5):1766-1778
20. Drakoularakou A, Tzortzis G, Rastall RA, Gibson GR (2010) A double-blind, placebo-controlled, randomized human study assessing the capacity of a novel galacto-oligosaccharide mixture in reducing travellers' diarrhoea. Eur J Clin Nutr 64:146-152
21. Dunne C, O'Mahony L, Murphy L, Thornton G, Morrissey D, O'Halloran S, Feeney M, Flynn S, Fitzgerald G, Daly C, Kiely B, O'Sullivan GC, Shanahan F, Collins JK (2001) In vitro selection criteria for probiotic bacteria of human origin: correlation with in vivo findings. Am J Clin Nutr 73(2 Suppl):386S-392S
22. Eaton TJ, Gasson MJ (2001) Molecular screening of Enterococcus virulence determinants and potential for genetic exchange between food and medical isolates. Appl Environ Microbiol 67(4):1628-1635
23. Eckburg PB, Bik EM, Bernstein CN, Purdom E, Dethlefsen L, Sargent M, Gill SR, Nelson KE, Relman DA (2005) Diversity of the Human Intestinal Microbial Flora. Science 308(5728):1635-1638
24. EFSA (2007) European Food Safety Authority Scientific Committee (EFSA) public consultation on the Qualified Presumption of Safety (QPS) approach for the safety assessment of microorganisms deliberately added to food and feed. Annex 3: Assessment of gram positive nonsporulating bacteria with respect to a qualified presumption of safety. http://www.efsa.europa. eu/en/science/sc- commitee/sc-consultations/sc-consultation-qps.html
25. El Nezami H, Kankaanpää P, Salminen S, Ahokas J (1998) Ability of dairy strains of lactic acid bacteria to bind a common food carcinogen, aflatoxin B1. Food Chem Toxicol 36(4):321-326
26. Enck P, Zimmermann K, Rusch K, Schwiertz A, Klosterhalfen S, Frick J (2009) The effects of maturation on the colonic microflora in infancy and childhood. Gastroenterol Res Pract. Published online 16 Sept 2009, doi:10.1155/2009/752401
27. Engelbrektson AL, Nguyen HD, Lung DY, Korzenik JR, Sanders ME, Leyer G, Klaenhammer TR, Kitts CL (2005) The effect of probiotics on the species distribution of Bifidobacterium and Lactobacillus in healthy subjects undergoing antibiotic therapy. Conference Proceeding
28. Fanaro S, Chierici R, Guerrini P, Vigi V (2003) Intestinal microflora in early infancy: composition and development. Acta Paediatr 92:48-55
29. FAO/WHO (2002) Guidelines for the evaluation of probiotics in food. http://www.who.int/foodsafety/publications/fs-management/probiotics2/en/. pp 1-11
30. Favier CF, Vaughan EE, de Vos WM, Akkermans ADL (2002) Molecular monitoring of succession of bacterial communities in human neonates. Appl Environ Microbiol 68(1):219-226
31. Finegold SM, Sutter VL, Mathisen GE (1983) Normal indigenous intestinal flora. In: Hentges DJ (ed) Human intestinal microflora in health and disease. Academic Press, New York, pp 3-31
32. Foligne B, Nutten S, Grangette C, Dennin V, Goudercourt D, Poiret S, Dewulf J, Brassart D, Mercenier A, Pot B (2007) Correlation between in vitro and in vivo immunomodulatory properties of lactic acid bacteria. World J Gastroenterol 13(2):236-243
33. Franks AH, Harmsen HJ, Raangs GC, Jansen GJ, Schut F, Welling GW (1998) Variations of bacterial populations in human faeces measured by fluorescent in situ hybridization with groupspecific 16S rRNA-targeted oligonucleotide probes. Appl Environ Microbiol 64(9):3336-3345
34. Fujiwara S, Seto Y, Kimura A, Hashiba H (2001) Intestinal transit of an orally administered streptomycin-rifampicin-resistant variant of Bifidobacterium longum SBT2928: its long-term survival and effect on the intestinal microflora and metabolism. J Appl Microbiol 90(1):43-52
35. Gavini F, Cayuela C, Antoine J-M, Lecoq C, Lefebvre B, Membreacute J-M, Neut C (2001) Differences in the distribution of bifidobacterial and enterobacterial species in human faecal microflora of three different (children, adults, elderly) age groups. Microb Ecol Health Dis 13(1):40-45
36. Gill HS, Rutherfurd KJ, Prasad J, Gopal PK (2000) Enhancement of natural and acquired immunity by Lactobacillus rhamnosus (HN001), Lactobacillus acidophilus (HN017) and Bifidobacterium lactis (HN019). Br J Nutr 83(2):167-176
37. Gill HS, Rutherfurd KJ, Cross ML, Gopal PK (2001) Enhancement of immunity in the elderly by dietary supplementation with the probiotic Bifidobacterium lactis HN019. Am J Clin Nut 74(6):833-839
38. Glück U, Gebbers J-O (2003) Ingested probiotics reduce nasal colonization with pathogenic bacteria (Staphylococcus aureus, Streptococcus pneumoniae, and ß-hemolytic streptococci). Am J Clin Nutr 77:517-520
39. Goldin BR, Gorbach SL (1984) The effect of milk and lactobacillus feeding on human intestinal bacterial enzyme activity. Am J Clin Nutr 39(5):756-761
40. Gopal P, Prasad J, Gill HS (2003) Effects of the consumption of Bifidobacterium lactis HN019 (DR10") and galacto-oligosaccharides on the microflora of the gastrointestinal tract in human subjects. Nutr Res 23:1313-1328
41. Gueimonde M, Delgado S, Baltasar M, Ruas-Madiedo P, Margolles A, los Reyes-Gavilan CG (2004) Viability and diversity of probiotic Lactobacillus and Bifidobacterium populations included in commercial fermented milks. Food Res Int 37:839-850
42. Guigoz Y, Dore J, Schiffrin EJ (2008) The inflammatory status of old age can be nurtured from the intestinal environment. Curr Opin Clin Nutr Metab Care 11(1):13-20
43. Haller D, Blum S, Bode C, Hammes WP, Schiffrin EJ (2000) Activation of human peripheral blood mononuclear cells by nonpathogenic bacteria in vitro: evidence of NK cells as primary targets. Infect Immun 68(2):752-759
44. Halttunen T, Salminen S, Tahvonen R (2007) Rapid removal of lead and cadmium from water by specific lactic acid bacteria. Int J Food Microbiol 114(1):30-35
45. Hamilton-Miller JM, Shah S, Winkler JT (1999) Public health issues arising from microbiological and labelling quality of foods and supplements containing probiotic microorganisms. Public Health Nutr 2(2):223-229
46. Harmsen HJM, Wildeboer-Veloo ACM, Raangs GC, Wagendorp AA, Klijn N, Bindels JG, Welling GW (2000) Analysis of intestinal flora development in breast-fed and formula-fed infants by using molecular identification and detection methods. J Pediat Gastroenterol Nutr 30(1):61-67
47. Harmsen HJM, Raangs GC, He T, Degener JE, Welling GW (2002) Extensive set of 16S rRNA-based probes for detection of bacteria in human faeces. Appl Environ Microbiol 68(6):2982-2990
48. Haskard CA, El Nezami HS, Kankaanpää PE, Salminen S, Ahokas JT (2001) Surface binding of aflatoxin B1 by lactic acid bacteria. Appl Environ Microbiol 67(7):3086-3091
49. Hawrelak JA, Myers SP (2004) The causes of intestinal dysbiosis: a review. Altern Med Rev 9(2):180-197
50. Hayashi H, Sakamoto M, Benno Y (2002) Phylogenetic analysis of the human gut microbiota using 16S rDNA clone libraries and strictly anaerobic culture-based methods. Microbiol Immunol 46(8):535-548
51. Hayashi H, Sakamoto M, Kitahara M, Benno Y (2003) Molecular analysis of faecal microbiota in elderly individuals using 16S rDNA library and T-RFLP. Microbiol Immunol 47(8):557-570
52. He F, Ouwehand AC, Isolauri E, Hosoda M, Benno Y, Salminen S (2001) Differences in composition and mucosal adhesion of bifidobacteria isolated from healthy adults and healthy seniors. Curr Microbiol 43(5):351-354
53. Holdeman LV, Good IJ, Moore WE (1976) Human faecal flora: variation in bacterial composition within individuals and a possible effect of emotional stress. Appl Environ Microbiol 31(3):359-375
54. Hopkins MJ, Macfarlane GT (2002) Changes in predominant bacterial populations in human faeces with age and with Clostridium difficile infection. J Med Microbiol 51(5):448-454
55. Hopkins MJ, Sharp R, Macfarlane GT (2001) Age and disease related changes in intestinal bacterial populations assessed by cell culture, 16S rRNA abundance, and community cellular fatty acid profiles. Gut 48(2):198-205
56. Jacobsen CN, Rosenfeldt Nielsen V, Hayford AE, Moller PL, Michaelsen KF, Paerregaard A, Sandstrom B, Tvede M, Jakobsen M (1999) Screening of probiotic activities of forty-seven strains of Lactobacillus spp. by in vitro techniques and evaluation of the colonization ability of five selected strains in humans. Appl Environ Microbiol 65(11):4949-4956
57. Johansson ME, Phillipson M, Petersson J, Velcich A, Holm L, Hansson GC (2008) The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria. Proc Natl Acad Sci U S A 105(39):15064-15069
58. Juntunen M, Kirjavainen P V, Ouwehand AC, Salminen SJ, Isolauri E (2001) Adherence of probiotic bacteria to human intestinal mucus in healthy infants and during rotavirus infection. Clin Diagn Lab Immunol 8(2):293-296
59. Kaplan CW, Astaire JC, Sanders ME, Reddy BS, Kitts CL (2001) 16S ribosomal DNA terminal restriction fragment pattern analysis of bacterial communities in faeces of rats fed Lactobacillus acidophilus NCFM. Appl Environ Microbiol 67(4):1935-1939
60. Karmeli Y, Stalnikowitz R, Eliakim R, Rahav G (1995) Conventional dose of omeprazole alters gastric flora. Dig Dis Sci 40(9):2070-2073
61. Kelly G (2008) Inulin-type prebiotics - a review: Part I. Alt Med Rev 13(4):315-329
62. Kirjavainen P V, El Nezami HS, Salminen SJ, Ahokas JT, Wright PF (1999) The effect of orally administered viable probiotic and dairy lactobacilli on mouse lymphocyte proliferation. FEMS Immunol Med Microbiol 26(2):131-135
63. Konstantinov SR, Smidt H, de Vos WM, Bruijns SC, Singh SK, Valence F, Molle D, Lortal S, Altermann E, Klaenhammer TR, van Kooyk Y (2008) S layer protein A of Lactobacillus acidophilus NCFM regulates immature dendritic cell and T cell functions. Proc Natl Acad Sci U S A 105(49):19474-19479
64. Kontula P, Jaskari J, Nollet L, De Smet I, von Wright A, Poutanen K, Mattila-Sandholm T (1998) The colonization of a simulator of the human intestinal microbial ecosystem by a probiotic strain fed on a fermented oat bran product: effects on the gastrointestinal microbiota. Appl Microbiol Biotechnol 50(2):246-252
65. Kwak G-S, Kim S-K, Jun. H-K (2001) Purification and characterization of bacteriocin J105 produced by Lactococcus lactis subsp. lactis J105 isolated from Kimchi. J Microbiol Biotechnol 11(2):275-280
66. Lahtinen SJ, Ouwehand AC, Reinikainen JP, Korpela JM, Sandholm J, Salminen SJ (2006) Intrinsic properties of so-called dormant probiotic bacteria, determined by flow cytometric viability assays. Appl Environ Microbiol 72(7):5132-5134
67. Lahtinen SJ, Tammela L, Korpela J, Parhiala R, Ahokoski H, Mykkanen H, Salminen SJ (2009) Probiotics modulate the Bifidobacterium microbiota of elderly nursing home residents. Age (Dordr.) 31(1):59-66
68. Laine R, Salminen S, Benno Y, Ouwehand AC (2003) Performance of bifidobacteria in oat-based media. Int J Food Microbiol 83(1):105-109
69. Laitinen K, Kalliomaki M, Poussa T, Lagstrom H, Isolauri E (2005) Evaluation of diet and growth in children with and without atopic eczema: follow-up study from birth to 4 years. Br J Nutr 94(4):565-574
70. Lay C, Rigottier-Gois L, Holmstrom K, Rajilic M, Vaughan EE, de Vos WM, Collins MD, Thiel R, Namsolleck P, Blaut M, Dore J (2005) Colonic microbiota signatures across five northern European countries. Appl Environ Microbiol 71(7):4153-4155
71. Layton A, McKay L, Williams D, Garrett V, Gentry R, Sayler G (2006) Development of Bacteroides 16S rRNA gene TaqMan-Based Real-Time PCR assays for estimation of total, human, and bovine faecal pollution in water. Appl Environ Microbiol 72(6):4214-4224
72. Lewis S, Burmeister S, Brazier J (2005a) Effect of the prebiotic oligofructose on relapse of Clostridium difficile-associated diarrhoea: a randomized, controlled study. Clin Gastroenterol Hepatol 3(5):442-448
73. Lewis S, Burmeister S, Cohen S, Brazier J, Awasthi A (2005b) Failure of dietary oligofructose to prevent antibiotic-associated diarrhoea. Aliment Pharmacol Ther 21(4):469-477
74. Leyer GJ, Li S, Mubasher ME, Reifer C, Ouwehand AC (2009) Probiotic effects on cold and influenza-like symptom incidence and duration in children. Pediatrics 124(2):e172-e179
75. Ljungberg B, Nilsson-Ehle I, Edlund C, Nord CE (1990) Influence of ciprofloxacin on the colonic microflora in young and elderly volunteers: no impact of the altered drug absorption. Scand J Infect Dis 22(2):205-208
76. Lofmark S, Jernberg C, Jansson JK, Edlund C (2006) Clindamycin-induced enrichment and longterm persistence of resistant Bacteroides spp. and resistance genes. J Antimicrob Chemother 58(6):1160-1167
77. Mackie RI, Sghir A, Gaskins HR (1999) Developmental microbial ecology of the neonatal gastrointestinal tract. Am J Clin Nutr 69(5):1035S-1045S
78. Madsen K, Cornish A, Soper P, McKaigney C, Jijon H, Yachimec C, Doyle J, Jewell L, De Simone C (2001) Probiotic bacteria enhance murine and human intestinal epithelial barrier function. Gastroenterology 121(3):580-591
79. Madueira AR, Giao MS, Pintado ME, Gomes AM, Freitas C, Malcata FX (2005) Incorporation and survival of probiotic bacteria in whey cheese matrices. J Food Sci 70(3):M160-M165
80. Mäkeläinen H, Tahvonen R, Salminen S, Ouwehand AC (2003) In vivo safety assessment of two Bifidobacterium longum strains. Microbiol Immunol 47(12):911-914
81. Mäkeläinen H, Forssten S, Olli K, Granlund L, Rautonen N, Ouwehand AC (2009) Probiotic lactobacilli in a semi-soft cheese survive in the simulated human gastrointestinal tract. Int Dairy J 19:675-683
82. Mäkeläinen HS, Mäkivuokko HA, Salminen SJ, Rautonen NE, Ouwehand AC (2007) The effects of polydextrose and xylitol on microbial community and activity in a 4-stage colon simulator. J Food Sci 72(5):M153-M159
83. Matto J, Maunuksela L, Kajander K, Palva A, Korpela R, Kassinen A, Saarela M (2005) Composition and temporal stability of gastrointestinal microbiota in irritable bowel syndrome - a longitudinal study in IBS and control subjects. FEMS Immunol Med Microbiol 43(2):213-222
84. McFarland LV (2006) Meta-analysis of probiotics for the prevention of antibiotic associated diarrhoea and the treatment of Clostridium difficile disease. Am J Gastroenterol 101(4):812-822
85. Meurman JH (2005) Probiotics: do they have a role in oral medicine and dentistry? Eur J Oral Sci 113(3):188-196
86. Mitsou EK, Kirtzalidou E, Oikonomou I, Liosis G, Kyriacou A (2008) Faecal microflora of Greek healthy neonates. Anaerobe 14(2):94-101
87. Mitsuoka T (1996) Intestinal flora and human health. Asia Pacific J Clin Nutr 5(1):2-9
88. Mowat AM (2003) Anatomical basis of tolerance and immunity to intestinal antigens. Nat Rev Immunol 3(4):331-341
89. Mueller S, Saunier K, Hanisch C, Norin E, Alm L, Midtvedt T, Cresci A, Silvi S, Orpianesi C, Verdenelli MC, Clavel T, Koebnick C, Zunft HJ, Dore J, Blaut M (2006) Differences in faecal microbiota in different European study populations in relation to age, gender, and country: a cross-sectional study. Appl Environ Microbiol 72(2):1027-1033
90. Nyberg SD, Osterblad M, Hakanen AJ, Lofmark S, Edlund C, Huovinen P, Jalava J (2007) Longterm antimicrobial resistance in Escherichia coli from human intestinal microbiota after administration of clindamycin. Scand J Infect Dis 39(6-7):514-520
91. Nybom SM, Salminen SJ, Meriluoto JA (2008) Specific strains of probiotic bacteria are efficient in removal of several different cyanobacterial toxins from solution. Toxicon 52(2):214-220
92. O'Hara AM, Shanahan F (2006) The gut flora as a forgotten organ. EMBO Rep 7(7):688-693
93. Orrhage K, Nord CE (1999) Factors controlling the bacterial colonization of the intestine in breastfed infants. Acta Paediatr 88:47-57
94. Orrhage K, Sillerström E, Gustafsson JA, Nord CE, Rafter J (1994) Binding of mutagenic heterocyclic amines by intestinal and lactic acid bacteria. Mutat Res 311(2):239-248
95. Osman N, Adawi D, Ahrne S, Jeppsson B, Molin G (2005) Probiotic strains of Lactobacillus and Bifidobacterium affect the translocation and intestinal load of Enterobacteriaceae differently after D-galactosamine-induced liver injury in rats. Microb Ecol Health Dis 17(1):40-46
96. Ouwehand AC, Lahtinen SJ (2008) The (non-) sense of human origin of probiotics. NutraCos 7:8-10
97. Ouwehand AC, Salminen S (1998) The health effects of cultured milk products with viable and non-viable bacteria. Int Dairy J 8:749-758
98. Ouwehand AC, Mäkeläinen H, Tiihonen K, Rautonen N (2006) Digestive health. In: Mitchell H (ed) Sweeteners and sugar alternatives in food technology, 1st edn. Blackwell Publishing, Oxford, pp 44-53
99. Paineau D, Carcano D, Leyer G, Darquy S, Alyanakian MA, Simoneau G, Bergmann JF, Brassart D, Bornet F, Ouwehand AC (2008) Effects of seven potential probiotic strains on specific immune responses in healthy adults: a double-blind, randomized, controlled trial. FEMS Immunol Med Microbiol 53(1):107-113
100. Paliy O, Kenche H, Abernathy F, Michail S (2009) High-throughput quantitative analysis of the human intestinal microbiota with a phylogenetic microarray. Appl Environ Microbiol 75(11):3572-3579
101. Palmer C, Bik EM, DiGiulio DB, Relman DA, Brown PO (2007) Development of the human infant intestinal microbiota. PLoS Biol 5(7):e177
102. Park HK, Shim SS, Kim SY, Park JH, Park SE, Kim HJ, Kang BC, Kim CM (2005) Molecular analysis of colonized bacteria in a human newborn infant gut. J Microbiol 43(4):345-353
103. Pavan S, Desreumaux P, Mercenier A (2003) Use of mouse models to evaluate the persistence, safety, and immune modulation capacities of lactic acid bacteria. Clin Diagn Lab Immunol 10(4):696-701
104. Petersen A, Heegaard PM, Pedersen AL, Andersen JB, Sorensen RB, Frokiaer H, Lahtinen SJ, Ouwehand AC, Poulsen M, Licht TR (2009) Some putative prebiotics increase the severity of Salmonella enterica serovar Typhimurium infection in mice. BMC Microbiol 9:245
105. Playne MJ, Crittenden RG (2008) Galacto-oligosaccharides. Production, properties and applications in foods. NutraFoods 7(1):9-18
106. Pool-Zobel BL, Neudecker C, Domizlaff I, Ji S, Schillinger U, Rumney C, Moretti M, Vilarini I, Scassellati-Sforzolini R, Rowland I (1996) Lactobacillus- and Bifidobacterium-mediated antigenotoxicity in the colon of rats. Nutr Cancer 26(3):365-380
107. Reid G (2008) Probiotic Lactobacilli for urogenital health in women. J Clin Gastroenterol (42 Suppl, 3 Pt) 2:S234-S236
108. Rousseaux C, Thuru X, Gelot A, Barnich N, Neut C, Dubuquoy L, Dubuquoy C, Merour E, Geboes K, Chamaillard M, Ouwehand A, Leyer G, Carcano D, Colombel JF, Ardid D, Desreumaux P (2006) Lactobacillus acidophilus modulates intestinal pain and induces opioid and cannabinoid receptors. Nat Med 13(1):35-37
109. Saarela M, Maukonen J, von Wright A, Vilpponen-Salmela T, Patterson AJ, Scott KP, Hämynen H, Mätto J (2007) Tetracycline susceptibility of the ingested Lactobacillus acidophilus LaCH-5 and Bifidobacterium animalis subsp. lactis Bb-12 strains during antibiotic/probiotic intervention. Int J Antimicrob Agent 29(3):271-280
110. Satokari RM, Vaughan EE, Favier CF, Doré J, Edwards C, Vos WM (2002) Diversity of Bifidobacterium and Lactobacillus spp. in breast-fed and formula-fed infants as assessed by 16S rDNA sequence differences. Microb Ecol Health Dis 14(2):97-105
111. Savage DC (1977) Microbial ecology of the gastrointestinal tract. Ann Rev Microbiol 31(1):107-133
112. Sazawal S, Hiremath G, Dhingra U, Malik P, Deb S, Black RE (2006) Efficacy of probiotics in prevention of acute diarrhoea: a meta-analysis of masked, randomised, placebo-controlled trials. Lancet Infect Dis 6(6):374-382
113. Scheppach W, Weiler F (2004) The butyrate story: old wine in new bottles. Curr Opin Clin Nutr Metabol Care 7:563-567
114. Schiffrin EJ, Brassart D, Servin AL, Rochat F, Donnet-Hughes A (1997) Immune modulation of blood leukocytes in humans by lactic acid bacteria: criteria for strain selection. Am J Clin Nutr 66(2):515S-520S
115. Schwiertz A, Gruhl B, Lobnitz M, Michel P, Radke M, Blaut M (2003) Development of the intestinal bacterial composition in hospitalized preterm infants in comparison with breast-fed, full-term infants. Pediatr Res 54(3):393-399
116. Sepp E, Julge K, Vasar M, Naaber P, Bjorksten B, Mikelsaar M (1997) Intestinal microflora of Estonian and Swedish infants. Acta Paediatr 86(9):956-961
117. Shu Q, Qu F, Gill HS (2001) Probiotic treatment using Bifidobacterium lactis HN019 reduces weanling diarrhoea associated with rotavirus and Escherichia coli infection in a piglet model. J Pediatr Gastroenterol Nutr 33(2):171-177
118. Stecher B, Hardt WD (2008) The role of microbiota in infectious disease. Trends Microbiol 16(3):107-114
119. Sullivan Å, Edlund C, Nord CE (2001) Effect of antimicrobial agents on the ecological balance of human microflora. Lancet Infect Dis 1(2):101-114
120. Szajewska H, Mrukowicz JZ (2001) Probiotics in the treatment and prevention of acute infectious diarrhoea in infants and children: a systematic review of published randomized, double blind, placebo-controlled trials. J Pediatr Gastroenterol Nutr 33:S17-S25
121. Tahara T, Oshimura M, Umezawa C, Kanatani K (1996) Isolation, partial characterization, and mode of action of acidocin J1132, a two component bacteriocin produced by Lactobacillus acidophilus JCM 1132. Appl Environ Microbiol 62(3):892-897
122. Tannock GW, Munro K, Harmsen HJM, Welling GW, Smart J, Gopal PK (2000) Analysis of the faecal microflora of human subjects consuming a probiotic product containing Lactobacillus rhamnosus DR20. Appl Environ Microbiol 66(6):2578-2588
123. Tiihonen K, Tynkkynen S, Ouwehand A, Ahlroos T, Rautonen, N. (2008) The effect of ageing with and without non-steroidal anti-inflammatory drugs on gastrointestinal microbiology and immunology. Br J Nutr 100(1):130-137
124. Tiihonen K, Ouwehand AC, Rautonen N (2010) Human intestinal microbiota and healthy ageing. Ageing Res Rev 9(2):107-116
125. Tompkins TA, Hagen KE, Wallace TD, Fillion-Forte V (2008) Safety evaluation of two bacterial strains used in Asian probiotic products. Can J Microbiol 54(5):391-400
126. Tuohy KM, Kolida S, Lustenberger AM, Gibson GR (2001) The prebiotic effects of biscuits containing partially hydrolysed guar gum and fructo-oligosaccharides - a human volunteer study. Br J Nutr 86:341-348
127. Turnbaugh PJ, Hamady M, Yatsunenko T, Cantarel BL, Duncan A, Ley RE, Sogin ML, Jones WJ, Roe BA, Affourtit JP, Egholm M, Henrissat B, Heath AC, Knight R, Gordon JI (2009) A core gut microbiome in obese and lean twins. Nature 457(7228):480-484
128. Valeur N, Engel P, Carbajal N, Connolly E, Ladefoged K (2004) Colonization and immunomodulation by Lactobacillus reuteri ATCC 55730 in the human gastrointestinal tract. Appl Environ Microbiol 70(2):1176-1181
129. van Tongeren SP, Slaets JPJ, Harmsen HJM, Welling GW (2005) Faecal microbiota composition and frailty. Appl Environ Microbiol 71(10):6438-6442
130. Vanhoutte T, Huys G, De Brandt E, Swings J (2004) Temporal stability analysis of the microbiota in human faeces by denaturing gradient gel electrophoresis using universal and group-specific 16S rRNA gene primers. FEMS Microbiol Ecol 48(3):437-446
131. Vankerckhoven V, Huys G, Vancanneyt M, Snauwaert C, Swings J, Klare I, Witte W, Van Autgaerden T, Chapelle S, Lammens C, Goossens H (2008) Genotypic diversity, antimicrobial resistance, and virulence factors of human isolates and probiotic cultures constituting two intraspecific groups of Enterococcus faecium isolates. Appl Environ Microbiol 74(14):4247-4255
132. Vesterlund S, Vankerckhoven V, Saxelin M, Goossens H, Salminen S, Ouwehand AC (2007) Safety assessment of Lactobacillus strains: presence of putative risk factors in faecal, blood and probiotic isolates. Int J Food Microbiol 116(3):325-331
133. Wagner RD, Warner T, Roberts L, Farmer J, Balish E (1997) Colonization of congenitally immunodeficient mice with probiotic bacteria. Infect Immun 65(8):3345-3351
134. Wagner RD, Pierson C, Warner T, Dohnalek M, Hilty M, Balish E (2000) Probiotic effects of feeding heat-killed Lactobacillus acidophilus and Lactobacillus casei to Candida albicanscolonized immunodeficient mice. J Food Protect 63(5):638-644
135. Wolf BW, Garleb KA, Ataya DG, Casas IA (1995) Safety and tolerance of Lactobacillus reuteri in healthy adult male subjects. Microb Ecol Health Dis 8(2):41-50
136. Wong C, Ustunol Z (2006) Mode of inactivation of probiotic bacteria affects interleukin 6 and interleukin 8 production in human intestinal epithelial-like Caco-2 cells. J Food Protect 69(9):2285-2288
137. Woodmansey EJ, McMurdo MET, Macfarlane GT, Macfarlane S (2004) Comparison of compositions and metabolic activities of faecal microbiotas in young adults and in antibiotic-treated and non-antibiotic-treated elderly subjects. Appl Environ Microbiol 70(10):6113-6122
138. Yildirim Z, Johnson MG (1998) Characterization and antimicrobial spectrum of bifidocin B, a bacteriocin produced by Bifidobacterium bifidum NCFB 1454. J Food Protect 61(1):47-51
139. Zhou JS, Shu Q, Rutherfurd KJ, Prasad J, Gopal PK, Gill HS (2000) Acute oral toxicity and bacterial translocation studies on potentially probiotic strains of lactic acid bacteria. Food Chem Toxicol 38(2-3):153-161
140. Zoetendal EG, Akkermans AD, de Vo s WM (1998) Temperature gradient gel electrophoresis analysis of 16S rRNA from human faecal samples reveals stable and host-specific communities of active bacteria. Appl Environ Microbiol 64(10):3854-3859
141. Zoetendal EG, Collier CT, Koike S, Mackie RI, Gaskins HR (2004) Molecular ecological analysis of the gastrointestinal microbiota: a review. J Nutr 134(2):465-472
142. Zoetendal EG, Rajilic-Stojanovic M, de Vo s WM (2008) High-throughput diversity and functionality analysis of the gastrointestinal tract microbiota. Gut 57(11):1605-1615
143. Zou J, Dong J, Yu X (2009) Meta-analysis: Lactobacillus containing quadruple therapy versus standard triple first-line therapy for Helicobacter pylori eradication. Helicobacter 14(5):97-107