Right- and left-loop short shRNAs have distinct and unusual mechanisms of gene silencing

Nucleic Acids Research

Volumn 40, Issue 18, 2012, Pages 9255-9271

  Dallas, Anne ^a   Ilves, Heini ^a   Ge, Qing ^a,e   Kumar, Pavan ^a,f   Shorenstein, Joshua ^a,g   Kazakov, Sergei A ^a   Cuellar, Trinna L ^b,h   McManus, Michael T ^b   Behlke, Mark A ^c   Johnston, Brian H ^a,d  

^a SomaGenics Inc   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c INTEGRATED DNA TECHNOLOGIES   (United States)

^d STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^f EISAI INC   (United States)

^g UNIVERSITY OF COLORADO   (United States)

^h GENENTECH INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGONAUTE 1 PROTEIN; ARGONAUTE 2 PROTEIN; MICRORNA; RNA INDUCED SILENCING COMPLEX; SHORT HAIRPIN RNA; SMALL INTERFERING RNA;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; EMBRYO; FIBROBLAST CULTURE; GENE ACTIVITY; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE REPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; INTERNAL RIBOSOME ENTRY SITE; KIDNEY CELL CULTURE; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN RNA BINDING; RNA CLEAVAGE; RNA INTERFERENCE; RNA SEQUENCE; SITE DIRECTED MUTAGENESIS;

ARGONAUTE PROTEINS; CELL LINE; HUMANS; IMMUNOPRECIPITATION; MICRORNAS; RIBONUCLEASE III; RNA CLEAVAGE; RNA INTERFERENCE; RNA PRECURSORS; RNA, SMALL INTERFERING; RNA-INDUCED SILENCING COMPLEX;

EID: 84867564182     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gks662     Document Type: Article

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