-
1
-
-
0347444723
-
MicroRNAs: Genomics, biogenesis, mechanism, and function
-
Bartel, D.P. (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell, 116, 281-297.
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
2
-
-
18344369543
-
MicroRNA biogenesis: Coordinated cropping and dicing
-
Kim, V.N. (2005) MicroRNA biogenesis: coordinated cropping and dicing. Nat. Rev. Mol. Cell. Biol., 6, 376-385.
-
(2005)
Nat. Rev. Mol. Cell. Biol.
, vol.6
, pp. 376-385
-
-
Kim, V.N.1
-
3
-
-
0344232733
-
MicroRNAs: Runts of the genome assert themselves
-
Lai, E.C. (2003) microRNAs: runts of the genome assert themselves. Curr. Biol., 13, R925-R936.
-
(2003)
Curr. Biol.
, vol.13
-
-
Lai, E.C.1
-
4
-
-
10644234841
-
The Drosha-DGCR8 complex in primary microRNA processing
-
Han, J., Lee, Y., Yeom, K.H., Kim, Y.K., Jin, H. and Kim, V.N. (2004) The Drosha-DGCR8 complex in primary microRNA processing. Genes Dev., 18, 3016-3027.
-
(2004)
Genes Dev.
, vol.18
, pp. 3016-3027
-
-
Han, J.1
Lee, Y.2
Yeom, K.H.3
Kim, Y.K.4
Jin, H.5
Kim, V.N.6
-
5
-
-
33744520104
-
Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex
-
Han, J., Lee, Y., Yeom, K.H., Nam, J.W., Heo, I., Rhee, J.K., Sohn, S.Y., Cho, Y., Zhang, B.T. and Kim, V.N. (2006) Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex. Cell, 125, 887-901.
-
(2006)
Cell
, vol.125
, pp. 887-901
-
-
Han, J.1
Lee, Y.2
Yeom, K.H.3
Nam, J.W.4
Heo, I.5
Rhee, J.K.6
Sohn, S.Y.7
Cho, Y.8
Zhang, B.T.9
Kim, V.N.10
-
6
-
-
0141843656
-
The nuclear RNase III Drosha initiates microRNA processing
-
Lee, Y., Ahn, C., Han, J., Choi, H., Kim, J., Yim, J., Lee, J., Provost, P., Radmark, O., Kim, S. et al. (2003) The nuclear RNase III Drosha initiates microRNA processing. Nature, 425, 415-419.
-
(2003)
Nature
, vol.425
, pp. 415-419
-
-
Lee, Y.1
Ahn, C.2
Han, J.3
Choi, H.4
Kim, J.5
Yim, J.6
Lee, J.7
Provost, P.8
Radmark, O.9
Kim, S.10
-
7
-
-
9144224451
-
Processing of primary microRNAs by the Microprocessor complex
-
Denli, A.M., Tops, B.B., Plasterk, R.H., Ketting, R.F. and Hannon, G.J. (2004) Processing of primary microRNAs by the Microprocessor complex. Nature, 432, 231-235.
-
(2004)
Nature
, vol.432
, pp. 231-235
-
-
Denli, A.M.1
Tops, B.B.2
Plasterk, R.H.3
Ketting, R.F.4
Hannon, G.J.5
-
8
-
-
9144225636
-
The Microprocessor complex mediates the genesis of microRNAs
-
Gregory, R.I., Yan, K.P., Amuthan, G., Chendrimada, T., Doratotaj, B., Cooch, N. and Shiekhattar, R. (2004) The Microprocessor complex mediates the genesis of microRNAs. Nature, 432, 235-240.
-
(2004)
Nature
, vol.432
, pp. 235-240
-
-
Gregory, R.I.1
Yan, K.P.2
Amuthan, G.3
Chendrimada, T.4
Doratotaj, B.5
Cooch, N.6
Shiekhattar, R.7
-
9
-
-
10344248903
-
The human DiGeorge syndrome critical region gene 8 and Its D.melanogaster homolog are required for miRNA biogenesis
-
Landthaler, M., Yalcin, A. and Tuschl, T. (2004) The human DiGeorge syndrome critical region gene 8 and Its D. melanogaster homolog are required for miRNA biogenesis. Curr. Biol., 14, 2162-2167.
-
(2004)
Curr. Biol.
, vol.14
, pp. 2162-2167
-
-
Landthaler, M.1
Yalcin, A.2
Tuschl, T.3
-
10
-
-
1642499415
-
Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs
-
Bohnsack, M.T., Czaplinski, K. and Gorlich, D. (2004) Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs. RNA, 10, 185-191.
-
(2004)
RNA
, vol.10
, pp. 185-191
-
-
Bohnsack, M.T.1
Czaplinski, K.2
Gorlich, D.3
-
11
-
-
0347988235
-
Nuclear export of microRNA precursors
-
Lund, E., Guttinger, S., Calado, A., Dahlberg, J.E. and Kutay, U. (2004) Nuclear export of microRNA precursors. Science, 303, 95-98.
-
(2004)
Science
, vol.303
, pp. 95-98
-
-
Lund, E.1
Guttinger, S.2
Calado, A.3
Dahlberg, J.E.4
Kutay, U.5
-
12
-
-
0347361541
-
Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs
-
Yi, R., Qin, Y., Macara, I.G. and Cullen, B.R. (2003) Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev., 17, 3011-3016.
-
(2003)
Genes Dev.
, vol.17
, pp. 3011-3016
-
-
Yi, R.1
Qin, Y.2
MacAra, I.G.3
Cullen, B.R.4
-
13
-
-
0035905766
-
Role for a bidentate ribonuclease in the initiation step of RNA interference
-
Bernstein, E., Caudy, A.A., Hammond, S.M. and Hannon, G.J. (2001) Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature, 409, 363-366.
-
(2001)
Nature
, vol.409
, pp. 363-366
-
-
Bernstein, E.1
Caudy, A.A.2
Hammond, S.M.3
Hannon, G.J.4
-
14
-
-
17844364875
-
Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing
-
Grishok, A., Pasquinelli, A.E., Conte, D., Li, N., Parrish, S., Ha, I., Baillie, D.L., Fire, A., Ruvkun, G. and Mello, C.C. (2001) Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing. Cell, 106, 23-34.
-
(2001)
Cell
, vol.106
, pp. 23-34
-
-
Grishok, A.1
Pasquinelli, A.E.2
Conte, D.3
Li, N.4
Parrish, S.5
Ha, I.6
Baillie, D.L.7
Fire, A.8
Ruvkun, G.9
Mello, C.C.10
-
15
-
-
0035800521
-
A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA
-
Hutvagner, G., McLachlan, J., Pasquinelli, A.E., Balint, E., Tuschl, T. and Zamore, P.D. (2001) A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science, 293, 834-838.
-
(2001)
Science
, vol.293
, pp. 834-838
-
-
Hutvagner, G.1
McLachlan, J.2
Pasquinelli, A.E.3
Balint, E.4
Tuschl, T.5
Zamore, P.D.6
-
16
-
-
0035887005
-
Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans
-
Ketting, R.F., Fischer, S.E., Bernstein, E., Sijen, T., Hannon, G.J. and Plasterk, R.H. (2001) Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans. Genes Dev., 15, 2654-2659.
-
(2001)
Genes Dev.
, vol.15
, pp. 2654-2659
-
-
Ketting, R.F.1
Fischer, S.E.2
Bernstein, E.3
Sijen, T.4
Hannon, G.J.5
Plasterk, R.H.6
-
17
-
-
0035929322
-
A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in Caenorhabditis elegans
-
Knight, S.W. and Bass, B.L. (2001) A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in Caenorhabditis elegans. Science, 293, 2269-2271.
-
(2001)
Science
, vol.293
, pp. 2269-2271
-
-
Knight, S.W.1
Bass, B.L.2
-
18
-
-
28044455435
-
MicroPrimer: The biogenesis and function of microRNA
-
Du, T. and Zamore, P.D. (2005) microPrimer: the biogenesis and function of microRNA. Development, 132, 4645-4652.
-
(2005)
Development
, vol.132
, pp. 4645-4652
-
-
Du, T.1
Zamore, P.D.2
-
19
-
-
0142165224
-
Functional siRNAs and miRNAs exhibit strand bias
-
Khvorova, A., Reynolds, A. and Jayasena, S.D. (2003) Functional siRNAs and miRNAs exhibit strand bias. Cell, 115, 209-216.
-
(2003)
Cell
, vol.115
, pp. 209-216
-
-
Khvorova, A.1
Reynolds, A.2
Jayasena, S.D.3
-
20
-
-
10744225153
-
Asymmetry in the assembly of the RNAi enzyme complex
-
Schwarz, D.S., Hutvagner, G., Du, T., Xu, Z., Aronin, N. and Zamore, P.D. (2003) Asymmetry in the assembly of the RNAi enzyme complex. Cell, 115, 199-208.
-
(2003)
Cell
, vol.115
, pp. 199-208
-
-
Schwarz, D.S.1
Hutvagner, G.2
Du, T.3
Xu, Z.4
Aronin, N.5
Zamore, P.D.6
-
21
-
-
66049133419
-
Mechanisms of miRNA-mediated post-transcriptional regulation in animal cells
-
Chekulaeva, M. and Filipowicz, W. (2009) Mechanisms of miRNA-mediated post-transcriptional regulation in animal cells. Curr. Opin. Cell Biol., 21, 452-460.
-
(2009)
Curr. Opin. Cell Biol.
, vol.21
, pp. 452-460
-
-
Chekulaeva, M.1
Filipowicz, W.2
-
22
-
-
38349169664
-
Mechanisms of post-transcriptional regulation by microRNAs: Are the answers in sight?
-
Filipowicz, W., Bhattacharyya, S.N. and Sonenberg, N. (2008) Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? Nat. Rev. Genet., 9, 102-114.
-
(2008)
Nat. Rev. Genet.
, vol.9
, pp. 102-114
-
-
Filipowicz, W.1
Bhattacharyya, S.N.2
Sonenberg, N.3
-
23
-
-
77955644289
-
Mammalian microRNAs predominantly act to decrease target mRNA levels
-
Guo, H., Ingolia, N.T., Weissman, J.S. and Bartel, D.P. (2010) Mammalian microRNAs predominantly act to decrease target mRNA levels. Nature, 466, 835-840.
-
(2010)
Nature
, vol.466
, pp. 835-840
-
-
Guo, H.1
Ingolia, N.T.2
Weissman, J.S.3
Bartel, D.P.4
-
24
-
-
33644768174
-
Control of translation and mRNA degradation by miRNAs and siRNAs
-
Valencia-Sanchez, M.A., Liu, J., Hannon, G.J. and Parker, R. (2006) Control of translation and mRNA degradation by miRNAs and siRNAs. Genes Dev., 20, 515-524.
-
(2006)
Genes Dev.
, vol.20
, pp. 515-524
-
-
Valencia-Sanchez, M.A.1
Liu, J.2
Hannon, G.J.3
Parker, R.4
-
25
-
-
54349104464
-
Mouse ES cells express endogenous shRNAs, siRNAs, and other Microprocessor-independent, Dicer-dependent small RNAs
-
Babiarz, J.E., Ruby, J.G., Wang, Y., Bartel, D.P. and Blelloch, R. (2008) Mouse ES cells express endogenous shRNAs, siRNAs, and other Microprocessor-independent, Dicer-dependent small RNAs. Genes Dev., 22, 2773-2785.
-
(2008)
Genes Dev.
, vol.22
, pp. 2773-2785
-
-
Babiarz, J.E.1
Ruby, J.G.2
Wang, Y.3
Bartel, D.P.4
Blelloch, R.5
-
26
-
-
73649109602
-
A mammalian herpesvirus uses noncanonical expression and processing mechanisms to generate viral MicroRNAs
-
Bogerd, H.P., Karnowski, H.W., Cai, X., Shin, J., Pohlers, M. and Cullen, B.R. (2010) A mammalian herpesvirus uses noncanonical expression and processing mechanisms to generate viral MicroRNAs. Mol. Cell, 37, 135-142.
-
(2010)
Mol. Cell
, vol.37
, pp. 135-142
-
-
Bogerd, H.P.1
Karnowski, H.W.2
Cai, X.3
Shin, J.4
Pohlers, M.5
Cullen, B.R.6
-
27
-
-
79551499254
-
Human box C/D snoRNAs with miRNA like functions: Expanding the range of regulatory RNAs
-
Brameier, M., Herwig, A., Reinhardt, R., Walter, L. and Gruber, J. (2011) Human box C/D snoRNAs with miRNA like functions: expanding the range of regulatory RNAs. Nucleic Acids Res., 39, 675-686.
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. 675-686
-
-
Brameier, M.1
Herwig, A.2
Reinhardt, R.3
Walter, L.4
Gruber, J.5
-
28
-
-
71549169628
-
Filtering of deep sequencing data reveals the existence of abundant Dicer-dependent small RNAs derived from tRNAs
-
Cole, C., Sobala, A., Lu, C., Thatcher, S.R., Bowman, A., Brown, J.W., Green, P.J., Barton, G.J. and Hutvagner, G. (2009) Filtering of deep sequencing data reveals the existence of abundant Dicer-dependent small RNAs derived from tRNAs. RNA, 15, 2147-2160.
-
(2009)
RNA
, vol.15
, pp. 2147-2160
-
-
Cole, C.1
Sobala, A.2
Lu, C.3
Thatcher, S.R.4
Bowman, A.5
Brown, J.W.6
Green, P.J.7
Barton, G.J.8
Hutvagner, G.9
-
29
-
-
55949112523
-
A human snoRNA with microRNA-like functions
-
Ender, C., Krek, A., Friedlander, M.R., Beitzinger, M., Weinmann, L., Chen, W., Pfeffer, S., Rajewsky, N. and Meister, G. (2008) A human snoRNA with microRNA-like functions. Mol. Cell, 32, 519-528.
-
(2008)
Mol. Cell
, vol.32
, pp. 519-528
-
-
Ender, C.1
Krek, A.2
Friedlander, M.R.3
Beitzinger, M.4
Weinmann, L.5
Chen, W.6
Pfeffer, S.7
Rajewsky, N.8
Meister, G.9
-
30
-
-
79955984020
-
Identification of human miRNA precursors that resemble box C/D snoRNAs
-
Ono, M., Scott, M.S., Yamada, K., Avolio, F., Barton, G.J. and Lamond, A.I. (2011) Identification of human miRNA precursors that resemble box C/D snoRNAs. Nucleic Acids Res., 39, 3879-3891.
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. 3879-3891
-
-
Ono, M.1
Scott, M.S.2
Yamada, K.3
Avolio, F.4
Barton, G.J.5
Lamond, A.I.6
-
31
-
-
70349661909
-
Human miRNA precursors with box H/ACA snoRNA features
-
Scott, M.S., Avolio, F., Ono, M., Lamond, A.I. and Barton, G.J. (2009) Human miRNA precursors with box H/ACA snoRNA features. PLoS Comput. Biol., 5, e1000507.
-
(2009)
PLoS Comput. Biol.
, vol.5
-
-
Scott, M.S.1
Avolio, F.2
Ono, M.3
Lamond, A.I.4
Barton, G.J.5
-
32
-
-
78149316877
-
Noncanonical cytoplasmic processing of viral microRNAs
-
Shapiro, J.S., Varble, A., Pham, A.M. and Tenoever, B.R. (2010) Noncanonical cytoplasmic processing of viral microRNAs. RNA, 16, 2068-2074.
-
(2010)
RNA
, vol.16
, pp. 2068-2074
-
-
Shapiro, J.S.1
Varble, A.2
Pham, A.M.3
Tenoever, B.R.4
-
33
-
-
67649386471
-
Small RNAs derived from snoRNAs
-
Taft, R.J., Glazov, E.A., Lassmann, T., Hayashizaki, Y., Carninci, P. and Mattick, J.S. (2009) Small RNAs derived from snoRNAs. RNA, 15, 1233-1240.
-
(2009)
RNA
, vol.15
, pp. 1233-1240
-
-
Taft, R.J.1
Glazov, E.A.2
Lassmann, T.3
Hayashizaki, Y.4
Carninci, P.5
Mattick, J.S.6
-
34
-
-
77953183812
-
A dicer-independent miRNA biogenesis pathway that requires Ago catalysis
-
Cheloufi, S., Dos Santos, C.O., Chong, M.M. and Hannon, G.J. (2010) A dicer-independent miRNA biogenesis pathway that requires Ago catalysis. Nature, 465, 584-589.
-
(2010)
Nature
, vol.465
, pp. 584-589
-
-
Cheloufi, S.1
Dos Santos, C.O.2
Chong, M.M.3
Hannon, G.J.4
-
35
-
-
77953897182
-
A novel miRNA processing pathway independent of Dicer requires Argonaute2 catalytic activity
-
Cifuentes, D., Xue, H., Taylor, D.W., Patnode, H., Mishima, Y., Cheloufi, S., Ma, E., Mane, S., Hannon, G.J., Lawson, N.D. et al. (2010) A novel miRNA processing pathway independent of Dicer requires Argonaute2 catalytic activity. Science, 328, 1694-1698.
-
(2010)
Science
, vol.328
, pp. 1694-1698
-
-
Cifuentes, D.1
Xue, H.2
Taylor, D.W.3
Patnode, H.4
Mishima, Y.5
Cheloufi, S.6
Ma, E.7
Mane, S.8
Hannon, G.J.9
Lawson, N.D.10
-
36
-
-
78649894176
-
Dicer-independent, Ago2-mediated microRNA biogenesis in vertebrates
-
Yang, J.S. and Lai, E.C. (2010) Dicer-independent, Ago2-mediated microRNA biogenesis in vertebrates. Cell Cycle, 9, 4455-4460.
-
(2010)
Cell Cycle
, vol.9
, pp. 4455-4460
-
-
Yang, J.S.1
Lai, E.C.2
-
37
-
-
77956995245
-
Conserved vertebrate mir-451 provides a platform for Dicer-independent, Ago2-mediated microRNA biogenesis
-
Yang, J.S., Maurin, T., Robine, N., Rasmussen, K.D., Jeffrey, K.L., Chandwani, R., Papapetrou, E.P., Sadelain, M., O'Carroll, D. and Lai, E.C. (2010) Conserved vertebrate mir-451 provides a platform for Dicer-independent, Ago2-mediated microRNA biogenesis. Proc. Natl Acad. Sci. USA, 107, 15163-15168.
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 15163-15168
-
-
Yang, J.S.1
Maurin, T.2
Robine, N.3
Rasmussen, K.D.4
Jeffrey, K.L.5
Chandwani, R.6
Papapetrou, E.P.7
Sadelain, M.8
O'Carroll, D.9
Lai, E.C.10
-
38
-
-
34447107760
-
The mirtron pathway generates microRNA-class regulatory RNAs in Drosophila
-
Okamura, K., Hagen, J.W., Duan, H., Tyler, D.M. and Lai, E.C. (2007) The mirtron pathway generates microRNA-class regulatory RNAs in Drosophila. Cell, 130, 89-100.
-
(2007)
Cell
, vol.130
, pp. 89-100
-
-
Okamura, K.1
Hagen, J.W.2
Duan, H.3
Tyler, D.M.4
Lai, E.C.5
-
39
-
-
34447097693
-
Intronic microRNA precursors that bypass Drosha processing
-
Ruby, J.G., Jan, C.H. and Bartel, D.P. (2007) Intronic microRNA precursors that bypass Drosha processing. Nature, 448, 83-86.
-
(2007)
Nature
, vol.448
, pp. 83-86
-
-
Ruby, J.G.1
Jan, C.H.2
Bartel, D.P.3
-
40
-
-
35348933779
-
Mammalian mirtron genes
-
Berezikov, E., Chung, W.J., Willis, J., Cuppen, E. and Lai, E.C. (2007) Mammalian mirtron genes. Mol. Cell, 28, 328-336.
-
(2007)
Mol. Cell
, vol.28
, pp. 328-336
-
-
Berezikov, E.1
Chung, W.J.2
Willis, J.3
Cuppen, E.4
Lai, E.C.5
-
41
-
-
44849106063
-
A microRNA catalog of the developing chicken embryo identified by a deep sequencing approach
-
Glazov, E.A., Cottee, P.A., Barris, W.C., Moore, R.J., Dalrymple, B.P. and Tizard, M.L. (2008) A microRNA catalog of the developing chicken embryo identified by a deep sequencing approach. Genome Res., 18, 957-964.
-
(2008)
Genome Res.
, vol.18
, pp. 957-964
-
-
Glazov, E.A.1
Cottee, P.A.2
Barris, W.C.3
Moore, R.J.4
Dalrymple, B.P.5
Tizard, M.L.6
-
42
-
-
50649110065
-
A diverse set of microRNAs and microRNA-like small RNAs in developing rice grains
-
Zhu, Q.H., Spriggs, A., Matthew, L., Fan, L., Kennedy, G., Gubler, F. and Helliwell, C. (2008) A diverse set of microRNAs and microRNA-like small RNAs in developing rice grains. Genome Res., 18, 1456-1465.
-
(2008)
Genome Res.
, vol.18
, pp. 1456-1465
-
-
Zhu, Q.H.1
Spriggs, A.2
Matthew, L.3
Fan, L.4
Kennedy, G.5
Gubler, F.6
Helliwell, C.7
-
43
-
-
77952368550
-
Mammalian microRNAs: Experimental evaluation of novel and previously annotated genes
-
Chiang, H.R., Schoenfeld, L.W., Ruby, J.G., Auyeung, V.C., Spies, N., Baek, D., Johnston, W.K., Russ, C., Luo, S., Babiarz, J.E. et al. (2010) Mammalian microRNAs: experimental evaluation of novel and previously annotated genes. Genes Dev., 24, 992-1009.
-
(2010)
Genes Dev.
, vol.24
, pp. 992-1009
-
-
Chiang, H.R.1
Schoenfeld, L.W.2
Ruby, J.G.3
Auyeung, V.C.4
Spies, N.5
Baek, D.6
Johnston, W.K.7
Russ, C.8
Luo, S.9
Babiarz, J.E.10
-
44
-
-
84855275505
-
The biogenesis and characterization of mammalian microRNAs of mirtron origin
-
Sibley, C.R., Seow, Y., Saayman, S., Dijkstra, K.K., El Andaloussi, S., Weinberg, M.S. and Wood, M.J. (2011) The biogenesis and characterization of mammalian microRNAs of mirtron origin. Nucleic Acids Res., 40, 438-448.
-
(2011)
Nucleic Acids Res.
, vol.40
, pp. 438-448
-
-
Sibley, C.R.1
Seow, Y.2
Saayman, S.3
Dijkstra, K.K.4
El Andaloussi, S.5
Weinberg, M.S.6
Wood, M.J.7
-
45
-
-
0037082158
-
High-level and high-throughput recombinant protein production by transient transfection of suspension-growing human 293-EBNA1 cells
-
Durocher, Y., Perret, S. and Kamen, A. (2002) High-level and high-throughput recombinant protein production by transient transfection of suspension-growing human 293-EBNA1 cells. Nucleic Acids Res., 30, E9.
-
(2002)
Nucleic Acids Res.
, vol.30
-
-
Durocher, Y.1
Perret, S.2
Kamen, A.3
-
46
-
-
4444368187
-
Argonaute2 is the catalytic engine of mammalian RNAi
-
Liu, J., Carmell, M.A., Rivas, F.V., Marsden, C.G., Thomson, J.M., Song, J.J., Hammond, S.M., Joshua-Tor, L. and Hannon, G.J. (2004) Argonaute2 is the catalytic engine of mammalian RNAi. Science, 305, 1437-1441.
-
(2004)
Science
, vol.305
, pp. 1437-1441
-
-
Liu, J.1
Carmell, M.A.2
Rivas, F.V.3
Marsden, C.G.4
Thomson, J.M.5
Song, J.J.6
Hammond, S.M.7
Joshua-Tor, L.8
Hannon, G.J.9
-
47
-
-
53949088050
-
Lin28 mediates the terminal uridylation of let-7 precursor MicroRNA
-
Heo, I., Joo, C., Cho, J., Ha, M., Han, J. and Kim, V.N. (2008) Lin28 mediates the terminal uridylation of let-7 precursor MicroRNA. Mol. Cell, 32, 276-284.
-
(2008)
Mol. Cell
, vol.32
, pp. 276-284
-
-
Heo, I.1
Joo, C.2
Cho, J.3
Ha, M.4
Han, J.5
Kim, V.N.6
-
48
-
-
24744441906
-
Characterization of Dicer-deficient murine embryonic stem cells
-
Murchison, E.P., Partridge, J.F., Tam, O.H., Cheloufi, S. and Hannon, G.J. (2005) Characterization of Dicer-deficient murine embryonic stem cells. Proc. Natl Acad. Sci. USA, 102, 12135-12140.
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 12135-12140
-
-
Murchison, E.P.1
Partridge, J.F.2
Tam, O.H.3
Cheloufi, S.4
Hannon, G.J.5
-
49
-
-
29144470346
-
Real-time quantification of microRNAs by stem-loop RT-PCR
-
Chen, C., Ridzon, D.A., Broomer, A.J., Zhou, Z., Lee, D.H., Nguyen, J.T., Barbisin, M., Xu, N.L., Mahuvakar, V.R., Andersen, M.R. et al. (2005) Real-time quantification of microRNAs by stem-loop RT-PCR. Nucleic Acids Res., 33, e179.
-
(2005)
Nucleic Acids Res.
, vol.33
-
-
Chen, C.1
Ridzon, D.A.2
Broomer, A.J.3
Zhou, Z.4
Lee, D.H.5
Nguyen, J.T.6
Barbisin, M.7
Xu, N.L.8
Mahuvakar, V.R.9
Andersen, M.R.10
-
50
-
-
65249134468
-
The C-terminal half of human Ago2 binds to multiple GW-rich regions of GW182 and requires GW182 to mediate silencing
-
Lian, S.L., Li, S., Abadal, G.X., Pauley, B.A., Fritzler, M.J. and Chan, E.K. (2009) The C-terminal half of human Ago2 binds to multiple GW-rich regions of GW182 and requires GW182 to mediate silencing. RNA, 15, 804-813.
-
(2009)
RNA
, vol.15
, pp. 804-813
-
-
Lian, S.L.1
Li, S.2
Abadal, G.X.3
Pauley, B.A.4
Fritzler, M.J.5
Chan, E.K.6
-
51
-
-
3242736704
-
Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs
-
Meister, G., Landthaler, M., Patkaniowska, A., Dorsett, Y., Teng, G. and Tuschl, T. (2004) Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs. Mol. Cell, 15, 185-197.
-
(2004)
Mol. Cell
, vol.15
, pp. 185-197
-
-
Meister, G.1
Landthaler, M.2
Patkaniowska, A.3
Dorsett, Y.4
Teng, G.5
Tuschl, T.6
-
52
-
-
80155194388
-
Amplification and sequencing of mature microRNAs in uncharacterized animal models using stem-loop reverse transcription-polymerase chain reaction
-
Biggar, K.K., Kornfeld, S.F. and Storey, K.B. (2011) Amplification and sequencing of mature microRNAs in uncharacterized animal models using stem-loop reverse transcription-polymerase chain reaction. Anal. Biochem., 416, 231-233.
-
(2011)
Anal. Biochem.
, vol.416
, pp. 231-233
-
-
Biggar, K.K.1
Kornfeld, S.F.2
Storey, K.B.3
-
53
-
-
79961132803
-
Quantitative stem-loop RT-PCR for detection of microRNAs
-
Varkonyi-Gasic, E. and Hellens, R.P. (2011) Quantitative stem-loop RT-PCR for detection of microRNAs. Methods Mol. Biol., 744, 145-157.
-
(2011)
Methods Mol. Biol.
, vol.744
, pp. 145-157
-
-
Varkonyi-Gasic, E.1
Hellens, R.P.2
-
54
-
-
55049135859
-
MicroRNA discovery and profiling in human embryonic stem cells by deep sequencing of small RNA libraries
-
Bar, M., Wyman, S.K., Fritz, B.R., Qi, J., Garg, K.S., Parkin, R.K., Kroh, E.M., Bendoraite, A., Mitchell, P.S., Nelson, A.M. et al. (2008) MicroRNA discovery and profiling in human embryonic stem cells by deep sequencing of small RNA libraries. Stem Cells, 26, 2496-2505.
-
(2008)
Stem Cells
, vol.26
, pp. 2496-2505
-
-
Bar, M.1
Wyman, S.K.2
Fritz, B.R.3
Qi, J.4
Garg, K.S.5
Parkin, R.K.6
Kroh, E.M.7
Bendoraite, A.8
Mitchell, P.S.9
Nelson, A.M.10
-
55
-
-
77950456855
-
Characterization of the Melanoma miRNAome by Deep Sequencing
-
Stark, M.S., Tyagi, S., Nancarrow, D.J., Boyle, G.M., Cook, A.L., Whiteman, D.C., Parsons, P.G., Schmidt, C., Sturm, R.A. and Hayward, N.K. (2010) Characterization of the Melanoma miRNAome by Deep Sequencing. PLoS One, 5, e9685.
-
(2010)
PLoS One
, vol.5
-
-
Stark, M.S.1
Tyagi, S.2
Nancarrow, D.J.3
Boyle, G.M.4
Cook, A.L.5
Whiteman, D.C.6
Parsons, P.G.7
Schmidt, C.8
Sturm, R.A.9
Hayward, N.K.10
-
56
-
-
28444469246
-
Silencing of microRNAs in vivo with 'antagomirs'
-
Krutzfeldt, J., Rajewsky, N., Braich, R., Rajeev, K.G., Tuschl, T., Manoharan, M. and Stoffel, M. (2005) Silencing of microRNAs in vivo with 'antagomirs'. Nature, 438, 685-689.
-
(2005)
Nature
, vol.438
, pp. 685-689
-
-
Krutzfeldt, J.1
Rajewsky, N.2
Braich, R.3
Rajeev, K.G.4
Tuschl, T.5
Manoharan, M.6
Stoffel, M.7
-
57
-
-
44649172429
-
MicroRNAs are tightly associated with RNA-induced gene silencing complexes in vivo
-
Tang, F., Hajkova, P., O'Carroll, D., Lee, C., Tarakhovsky, A., Lao, K. and Surani, M.A. (2008) MicroRNAs are tightly associated with RNA-induced gene silencing complexes in vivo. Biochem. Biophys. Res. Commun., 372, 24-29.
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.372
, pp. 24-29
-
-
Tang, F.1
Hajkova, P.2
O'Carroll, D.3
Lee, C.4
Tarakhovsky, A.5
Lao, K.6
Surani, M.A.7
-
58
-
-
33847323881
-
DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal
-
Wang, Y., Medvid, R., Melton, C., Jaenisch, R. and Blelloch, R. (2007) DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal. Nat. Genet., 39, 380-385.
-
(2007)
Nat. Genet.
, vol.39
, pp. 380-385
-
-
Wang, Y.1
Medvid, R.2
Melton, C.3
Jaenisch, R.4
Blelloch, R.5
-
59
-
-
0037009364
-
MicroRNA maturation: Stepwise processing and subcellular localization
-
Lee, Y., Jeon, K., Lee, J.T., Kim, S. and Kim, V.N. (2002) MicroRNA maturation: stepwise processing and subcellular localization. EMBO J., 21, 4663-4670.
-
(2002)
EMBO J.
, vol.21
, pp. 4663-4670
-
-
Lee, Y.1
Jeon, K.2
Lee, J.T.3
Kim, S.4
Kim, V.N.5
-
60
-
-
77955500933
-
MicroRNA biogenesis via splicing and exosome-mediated trimming in Drosophila
-
Flynt, A.S., Greimann, J.C., Chung, W.J., Lima, C.D. and Lai, E.C. (2010) MicroRNA biogenesis via splicing and exosome-mediated trimming in Drosophila. Mol. Cell, 38, 900-907.
-
(2010)
Mol. Cell
, vol.38
, pp. 900-907
-
-
Flynt, A.S.1
Greimann, J.C.2
Chung, W.J.3
Lima, C.D.4
Lai, E.C.5
-
61
-
-
77956278269
-
Canonical and alternate functions of the microRNA biogenesis machinery
-
Chong, M.M., Zhang, G., Cheloufi, S., Neubert, T.A., Hannon, G.J. and Littman, D.R. (2010) Canonical and alternate functions of the microRNA biogenesis machinery. Genes Dev., 24, 1951-1960.
-
(2010)
Genes Dev.
, vol.24
, pp. 1951-1960
-
-
Chong, M.M.1
Zhang, G.2
Cheloufi, S.3
Neubert, T.A.4
Hannon, G.J.5
Littman, D.R.6
-
62
-
-
58849112575
-
Biogenesis of small RNAs in animals
-
Kim, V.N., Han, J. and Siomi, M.C. (2009) Biogenesis of small RNAs in animals. Nat. Rev. Mol. Cell. Biol., 10, 126-139.
-
(2009)
Nat. Rev. Mol. Cell. Biol.
, vol.10
, pp. 126-139
-
-
Kim, V.N.1
Han, J.2
Siomi, M.C.3
-
63
-
-
54949147637
-
Splicing factors facilitate RNAi-directed silencing in fission yeast
-
Bayne, E.H., Portoso, M., Kagansky, A., Kos-Braun, I.C., Urano, T., Ekwall, K., Alves, F., Rappsilber, J. and Allshire, R.C. (2008) Splicing factors facilitate RNAi-directed silencing in fission yeast. Science, 322, 602-606.
-
(2008)
Science
, vol.322
, pp. 602-606
-
-
Bayne, E.H.1
Portoso, M.2
Kagansky, A.3
Kos-Braun, I.C.4
Urano, T.5
Ekwall, K.6
Alves, F.7
Rappsilber, J.8
Allshire, R.C.9
-
64
-
-
67649277689
-
The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs
-
Trabucchi, M., Briata, P., Garcia-Mayoral, M., Haase, A.D., Filipowicz, W., Ramos, A., Gherzi, R. and Rosenfeld, M.G. (2009) The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs. Nature, 459, 1010-1014.
-
(2009)
Nature
, vol.459
, pp. 1010-1014
-
-
Trabucchi, M.1
Briata, P.2
Garcia-Mayoral, M.3
Haase, A.D.4
Filipowicz, W.5
Ramos, A.6
Gherzi, R.7
Rosenfeld, M.G.8
-
65
-
-
77950357450
-
A splicing-independent function of SF2/ASF in microRNA processing
-
Wu, H., Sun, S., Tu, K., Gao, Y., Xie, B., Krainer, A.R. and Zhu, J. (2010) A splicing-independent function of SF2/ASF in microRNA processing. Mol. Cell, 38, 67-77.
-
(2010)
Mol. Cell
, vol.38
, pp. 67-77
-
-
Wu, H.1
Sun, S.2
Tu, K.3
Gao, Y.4
Xie, B.5
Krainer, A.R.6
Zhu, J.7
-
66
-
-
34447115822
-
The multifunctional RNA-binding protein hnRNP A1 is required for processing of miR-18a
-
Guil, S. and Caceres, J.F. (2007) The multifunctional RNA-binding protein hnRNP A1 is required for processing of miR-18a. Nat. Struct. Mol. Biol., 14, 591-596.
-
(2007)
Nat. Struct. Mol. Biol.
, vol.14
, pp. 591-596
-
-
Guil, S.1
Caceres, J.F.2
-
67
-
-
77956034926
-
Novel endoribonucleases as central players in various pathways of eukaryotic RNA metabolism
-
Tomecki, R. and Dziembowski, A. (2010) Novel endoribonucleases as central players in various pathways of eukaryotic RNA metabolism. RNA, 16, 1692-1724.
-
(2010)
RNA
, vol.16
, pp. 1692-1724
-
-
Tomecki, R.1
Dziembowski, A.2
-
68
-
-
33847784925
-
Eukaryotic RNase P RNA mediates cleavage in the absence of protein
-
Kikovska, E., Svard, S.G. and Kirsebom, L.A. (2007) Eukaryotic RNase P RNA mediates cleavage in the absence of protein. Proc. Natl Acad. Sci. USA, 104, 2062-2067.
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 2062-2067
-
-
Kikovska, E.1
Svard, S.G.2
Kirsebom, L.A.3
-
69
-
-
29044449835
-
The tRNase Z family of proteins: Physiological functions substrate specificity and structural properties
-
Vogel, A., Schilling, O., Spath, B. and Marchfelder, A. (2005) The tRNase Z family of proteins: physiological functions, substrate specificity and structural properties. Biol. Chem., 386, 1253-1264.
-
(2005)
Biol. Chem.
, vol.386
, pp. 1253-1264
-
-
Vogel, A.1
Schilling, O.2
Spath, B.3
Marchfelder, A.4
-
70
-
-
2042479408
-
Identification of a human endonuclease complex reveals a link between tRNA splicing and pre-mRNA 3' end formation
-
Paushkin, S.V., Patel, M., Furia, B.S., Peltz, S.W. and Trotta, C.R. (2004) Identification of a human endonuclease complex reveals a link between tRNA splicing and pre-mRNA 3' end formation. Cell, 117, 311-321.
-
(2004)
Cell
, vol.117
, pp. 311-321
-
-
Paushkin, S.V.1
Patel, M.2
Furia, B.S.3
Peltz, S.W.4
Trotta, C.R.5
-
71
-
-
0030730820
-
The yeast tRNA splicing endonuclease: A tetrameric enzyme with two active site subunits homologous to the archaeal tRNA endonucleases
-
Trotta, C.R., Miao, F., Arn, E.A., Stevens, S.W., Ho, C.K., Rauhut, R. and Abelson, J.N. (1997) The yeast tRNA splicing endonuclease: a tetrameric enzyme with two active site subunits homologous to the archaeal tRNA endonucleases. Cell, 89, 849-858.
-
(1997)
Cell
, vol.89
, pp. 849-858
-
-
Trotta, C.R.1
Miao, F.2
Arn, E.A.3
Stevens, S.W.4
Ho, C.K.5
Rauhut, R.6
Abelson, J.N.7
-
72
-
-
33846945735
-
Processing of intronic microRNAs
-
Kim, Y.K. and Kim, V.N. (2007) Processing of intronic microRNAs. EMBO J., 26, 775-783.
-
(2007)
EMBO J.
, vol.26
, pp. 775-783
-
-
Kim, Y.K.1
Kim, V.N.2
-
73
-
-
51349103700
-
Primary microRNA transcripts are processed co-transcriptionally
-
Morlando, M., Ballarino, M., Gromak, N., Pagano, F., Bozzoni, I. and Proudfoot, N.J. (2008) Primary microRNA transcripts are processed co-transcriptionally. Nat. Struct. Mol. Bio.l, 15, 902-909.
-
(2008)
Nat. Struct. Mol. Bio.l
, vol.15
, pp. 902-909
-
-
Morlando, M.1
Ballarino, M.2
Gromak, N.3
Pagano, F.4
Bozzoni, I.5
Proudfoot, N.J.6
-
74
-
-
80052263337
-
Autosomal dominant polycystic kidney disease: Genetics, mutations and microRNAs
-
Tan, Y.C., Blumenfeld, J. and Rennert, H. (2011) Autosomal dominant polycystic kidney disease: genetics, mutations and microRNAs. Biochim. Biophys. Acta, 1812, 1202-1212.
-
(2011)
Biochim. Biophys. Acta
, vol.1812
, pp. 1202-1212
-
-
Tan, Y.C.1
Blumenfeld, J.2
Rennert, H.3
-
75
-
-
80054714430
-
Hepatic and renal manifestations in autosomal dominant polycystic kidney disease: A dichotomy of two ends of a spectrum
-
van Gulick, J.J., Gevers, T.J., van Keimpema, L. and Drenth, J.P. (2011) Hepatic and renal manifestations in autosomal dominant polycystic kidney disease: a dichotomy of two ends of a spectrum. Neth. J. Med., 69, 367-371.
-
(2011)
Neth. J. Med.
, vol.69
, pp. 367-371
-
-
Van Gulick, J.J.1
Gevers, T.J.2
Van Keimpema, L.3
Drenth, J.P.4
-
76
-
-
0034320194
-
Novel splicing and missense mutations in autosomal dominant polycystic kidney disease 1 (PKD1) gene: Expression of mutated genes
-
Aguiari, G., Savelli, S., Garbo, M., Bozza, A., Augello, G., Penolazzi, L., De Paoli Vitali, E., La Torre, C., Cappelli, G., Piva, R. et al. (2000) Novel splicing and missense mutations in autosomal dominant polycystic kidney disease 1 (PKD1) gene: expression of mutated genes. Hum. Mutat., 16, 444-445.
-
(2000)
Hum. Mutat.
, vol.16
, pp. 444-445
-
-
Aguiari, G.1
Savelli, S.2
Garbo, M.3
Bozza, A.4
Augello, G.5
Penolazzi, L.6
De Paoli Vitali, E.7
La Torre, C.8
Cappelli, G.9
Piva, R.10
-
77
-
-
0032920372
-
Mutational analysis within the 30 region of the PKD1 gene
-
Badenas, C., Torra, R., San Millan, J.L., Lucero, L., Mila, M., Estivill, X. and Darnell, A. (1999) Mutational analysis within the 30 region of the PKD1 gene. Kidney Int., 55, 1225-1233.
-
(1999)
Kidney Int.
, vol.55
, pp. 1225-1233
-
-
Badenas, C.1
Torra, R.2
San Millan, J.L.3
Lucero, L.4
Mila, M.5
Estivill, X.6
Darnell, A.7
-
78
-
-
0036081948
-
Mutation screening of the PKD1 transcript by RT-PCR
-
Burtey, S., Lossi, A.M., Bayle, J., Berland, Y. and Fontes, M. (2002) Mutation screening of the PKD1 transcript by RT-PCR. J. Med. Genet., 39, 422-429.
-
(2002)
J. Med. Genet.
, vol.39
, pp. 422-429
-
-
Burtey, S.1
Lossi, A.M.2
Bayle, J.3
Berland, Y.4
Fontes, M.5
-
79
-
-
50349092250
-
LDL receptor-related protein 1: Unique tissue-specific functions revealed by selective gene knockout studies
-
Lillis, A.P., Van Duyn, L.B., Murphy-Ullrich, J.E. and Strickland, D.K. (2008) LDL receptor-related protein 1: unique tissue-specific functions revealed by selective gene knockout studies. Physiol. Rev., 88, 887-918.
-
(2008)
Physiol. Rev.
, vol.88
, pp. 887-918
-
-
Lillis, A.P.1
Van Duyn, L.B.2
Murphy-Ullrich, J.E.3
Strickland, D.K.4
-
80
-
-
78649461312
-
A feedback loop regulates splicing of the spinal muscular atrophy-modifying gene, SMN2
-
Jodelka, F.M., Ebert, A.D., Duelli, D.M. and Hastings, M.L. (2010) A feedback loop regulates splicing of the spinal muscular atrophy-modifying gene, SMN2. Hum. Mol. Genet., 19, 4906-4917.
-
(2010)
Hum. Mol. Genet.
, vol.19
, pp. 4906-4917
-
-
Jodelka, F.M.1
Ebert, A.D.2
Duelli, D.M.3
Hastings, M.L.4
-
81
-
-
39049152539
-
Relative quantification of mRNA: Comparison of methods currently used for real-time PCR data analysis
-
Cikos, S., Bukovska, A. and Koppel, J. (2007) Relative quantification of mRNA: comparison of methods currently used for real-time PCR data analysis. BMC Mol. Biol., 8, 113.
-
(2007)
BMC Mol. Biol.
, vol.8
, pp. 113
-
-
Cikos, S.1
Bukovska, A.2
Koppel, J.3
|