Drug discovery through stem cell-based organoid models

Advanced Drug Delivery Reviews

Volumn 69-70, Issue , 2014, Pages 19-28

  Ranga, Adrian ^a   Gjorevski, Nikolche ^a   Lutolf, Matthias P ^a  

^a EPFL   (Switzerland)

Author keywords

3D cell culture; Drug discovery; High throughput screening; Organoid; Stem cell

Indexed keywords

BIOACTIVITY; BIOMIMETICS; CELL CULTURE; STEM CELLS;

3-D CELL CULTURE; DRUG CANDIDATES; DRUG DEVELOPMENT; DRUG DISCOVERY; HIGH-THROUGHPUT SCREENING; ORGANOID; ORGANOID CULTURES; PROOF OF CONCEPT;

DRUG PRODUCTS;

DRUG;

ANGIOGENESIS; ARTIFICIAL LIVER; ARTIFICIAL ORGAN; BIOENGINEERING; BIOLOGICAL ACTIVITY; BIOLOGICAL MODEL; BIOTECHNOLOGY; BRAIN; CELL ASSAY; CELL INVASION; CELL MIGRATION; COCULTURE; CULTURE TECHNIQUE; DRUG DEVELOPMENT; DRUG RESPONSE; DRUG SCREENING; EMBRYONIC STEM CELL; EXTRACELLULAR MATRIX; GENETIC SCREENING; HIGH THROUGHPUT SCREENING; HUMAN; HYDROGEL; IN VITRO STUDY; INTESTINE; LYMPHANGIOGENESIS; MICROENVIRONMENT; MULTICELLULAR SPHEROID; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROCESS OPTIMIZATION; REVIEW; STEM CELL; TOXICITY TESTING; TUMOR SPHEROID; ANIMAL; CYTOLOGY; CYTOPLASM; DRUG EFFECTS; DRUG-RELATED SIDE EFFECTS AND ADVERSE REACTIONS; PHYSIOLOGY; PROCEDURES; TRENDS;

ANIMALS; DRUG DISCOVERY; DRUG EVALUATION, PRECLINICAL; DRUG-RELATED SIDE EFFECTS AND ADVERSE REACTIONS; HUMANS; ORGANOIDS; STEM CELLS;

EID: 84899982894     PISSN: 0169409X     EISSN: 18728294     Source Type: Journal    
DOI: 10.1016/j.addr.2014.02.006     Document Type: Review

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