An HTS-compatible 3D colony formation assay to identify tumor-specific chemotherapeutics

Journal of Biomolecular Screening

Volumn 18, Issue 10, 2013, Pages 1298-1308

  Horman, Shane R ^a   To, Jeremy ^a   Orth, Anthony P ^a  

^a GENOMICS INSTITUTE OF THE NOVARTIS RESEARCH FOUNDATION   (United States)

Author keywords

3D assay development; co culture; colon; colony formation; high content screening; HTS; soft agar

Indexed keywords

DOXORUBICIN; FLUOROURACIL; GEFITINIB; NATURAL PRODUCT; STAUROSPORINE;

ARTICLE; ASSAY; CANCER CELL; CELL ASSAY; CELL GROWTH; CELL POPULATION; CELL TYPE; CELL VIABILITY; CHEMOTHERAPY; COCULTURE; COLONY FORMATION; COLONY FORMATION ASSAY; COLORECTAL CARCINOMA; CONTROLLED STUDY; EPITHELIUM CELL; FLUORESCENCE; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; IC 50; IMAGE ANALYSIS; LASER SCANNING CYTOMETRY; PRIORITY JOURNAL; SIGNAL NOISE RATIO; STROMA CELL;

3D ASSAY DEVELOPMENT; CO-CULTURE; COLON; COLONY FORMATION; HIGH-CONTENT SCREENING; HTS; SOFT AGAR;

ANTINEOPLASTIC AGENTS; COCULTURE TECHNIQUES; DRUG SCREENING ASSAYS, ANTITUMOR; HCT116 CELLS; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; INHIBITORY CONCENTRATION 50; SMALL MOLECULE LIBRARIES;

EID: 84887877208     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057113499405     Document Type: Article

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