An extracellular matrix microarray for probing cellular differentiation

Nature Methods

Volumn 2, Issue 2, 2005, Pages 119-125

  Flaim, Christopher J ^a   Chien, Shu ^a   Bhatia, Sangeeta N ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; BETA GALACTOSIDASE; COLLAGEN TYPE 1; COLLAGEN TYPE 3; COLLAGEN TYPE 4; FIBRONECTIN; LAMININ; SCLEROPROTEIN;

ANIMAL CELL; ANKRD17 GENE; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL FATE; CELL FUNCTION; CELL TYPE; COMBINATORIAL CHEMISTRY; EMBRYO; EMBRYO CELL; EXTRACELLULAR MATRIX; EXTRACELLULAR MATRIX MICROARRAY; FETUS LIVER; GENE; LIVER CELL; MOLECULAR PROBE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; STEM CELL; ANIMAL; CELL LINE; CHEMISTRY; COMPARATIVE STUDY; CULTURE TECHNIQUE; CYTOLOGY; DRUG EFFECT; EQUIPMENT; EQUIPMENT DESIGN; EVALUATION; GENETIC PROCEDURES; INSTRUMENTATION; METHODOLOGY; MICROARRAY ANALYSIS; MICROFLUIDIC ANALYSIS; MOUSE; PHYSIOLOGY; ROBOTICS;

ANIMALIA;

ANIMALS; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELL LINE; COMBINATORIAL CHEMISTRY TECHNIQUES; EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; EXTRACELLULAR MATRIX PROTEINS; HEPATOCYTES; MICE; MICROARRAY ANALYSIS; MICROFLUIDIC ANALYTICAL TECHNIQUES; MOLECULAR PROBE TECHNIQUES; RATS; ROBOTICS; STEM CELLS;

EID: 18744376054     PISSN: 15487091     EISSN: None     Source Type: Journal    
DOI: 10.1038/nmeth736     Document Type: Article

References (60)

1. Ding, S. et al. Synthetic small molecules that control stem cell fate. Proc. Natl. Acad. Sci. USA 100, 7632-7637 (2003).
2. Revzin, A. et al. Designing a hepatocellular microenvironment with protein microarraying and poly(ethylene glycol) photolithography. Langmuir 20, 2999-3005 (2004).
3. Prudhomme, W., Daley, G.Q., Zandstra, P. & Lauffenburger, D.A. Multivariate proteomic analysis of murine embryonic stem cell self-renewal versus differentiation signaling. Proc. Natl. Acad. Sci. USA 101, 2900-2905 (2004).
4. Anderson, D.G., Levenberg, S. & Langer, R. Nanoliter-scale synthesis of arrayed biomateriats and application to human embryonic stem cells. Nat. Biotechnol. 22, 863-866 (2004).
5. Meredith, J.E. Jr. et al. The regulation of growth and intracellular signaling by integrins. Endocr. Rev. 17, 207-220 (1996).
6. Comoglio, P.M., Boccaccio, C. & Trusolino, L. Interactions between growth factor receptors and adhesion molecules: breaking the rules. Curr. Opin. Cell Biol. 15, 565-571 (2003).
7. Hall, H.G., Farson, D.A. & Bissell, M.J. Lumen formation by epithelial cell lines in response to collagen overlay: a morphogenetic model in culture. Proc. Natl. Acad. Sci. USA 79, 4672-4676 (1982).
8. Dunn, J.C., Yarmush, M.L., Koebe, H.G. & Tompkins, R.G. Hepatocyte function and extracellular matrix geometry: long-term culture in a sandwich configuration. FASEB J. 3, 174-177 (1989).
9. Cukierman, E., Pankov, R., Stevens, D.R. & Yamada, K.M. Taking cell-matrix adhesions to the third dimension. Science 294, 1708-1712 (2001).
10. Baatout, S. Endothelial differentiation using Matrigel (review). Anticancer Res. 17, 451-455 (1997).
11. Lindberg, K. & Badylak, S.F. Porcine small intestinal submucosa (SIS): a bioscaffold supporting in vitro primary human epidermal cell differentiation and synthesis of basement membrane proteins. Burns 27, 254-266 (2001).
12. Lin, P., Chan, W.C.W., Badylak, S. & Bhatia, S. Assessing the function of porcine liver-derived matrix: applications to hepatic tissue engineering. Tissue Eng. 10, 1046-1053 (2004).
13. Mann, B.K., Gobin, A.S., Tsai, A.T., Schmedlen, R.H. & West, J.L. Smooth muscle cell growth in photopolymerized hydrogels with cell adhesive and proteolytically degradable domains: synthetic ECM analogs for tissue engineering. Biomaterials 22, 3045-3051 (2001).
14. Hern, D.L. & Hubbell, J.A. Incorporation of adhesion peptides into nonadhesive hydrogels useful for tissue resurfacing. J. Biomed. Mater. Res. 39, 266-276 (1998).
15. Anseth, K.S., Shastri, V.R. & Langer, R. Photopolymerizable degradable polyanhydrides with osteocompatibility. Nat. Biotechnol. 17, 156-159 (1999).
16. Singhvi, R. et al. Engineering cell-shape and function. Science 264, 696-698 (1994).
17. Chen, C.S., Mrksich, M., Huang, S., Whitesides, G.M. & Ingber, D.E. Geometric control of cell life and death. Science 276, 1425-1428 (1997).
18. Bhatia, S.N., Yarmush, M.L. & Toner, M. Controlling cell interactions by micropatterning in co-cultures: hepatocytes and 3T3 fibroblasts. J. Biomed. Mater. Res. 34, 189-199 (1997).
19. Kane, R.S., Takayama, S., Ostuni, E., Ingber, D.E. & Whitesides, G.M. Patterning proteins and cells using soft lithography. Biomaterials 20, 2363-2376 (1999).
20. MacBeath, G. & Schreiber, S.L. Printing proteins as microarrays for high-throughput function determination. Science 289, 1760-1763 (2000).
21. Houseman, B.T. & Mrksich, M. Carbohydrate arrays for the evaluation of protein binding and enzymatic modification. Chem. Biol. 9, 443-454 (2002).
22. Falsey, J.R., Renil, M., Park, S., Li, S.J. & Lam, K.S. Peptide and small molecule microarray for high throughput cell adhesion and functional assays. Bioconj. Chem. 12, 346-353 (2001).
23. Ziauddin, J. & Sabatini, D.M. Microarrays of cells expressing defined cDNAs. Nature 411, 107-110 (2001).
24. Mousses, S. et al. RNAi microarray analysis in cultured mammalian cells. Genome Res. 13, 2341-2347 (2003).
25. Forrester, L.M. et al. An induction gene trap screen in embryonic stem cells: Identification of genes that respond to retinoic acid in vitro. Proc. Natl. Acad. Sci. USA 93, 1677-1682 (1996).
26. Watt, A.J. et al. A gene trap integration provides an early in situ marker for hepatic specification of the foregut endoderm. Mech. Dev. 100, 205-215 (2001).
27. Sudhakaran, P.R., Stamatoglou, S.C. & Hughes, R.C. Modulation of protein synthesis and secretion by substratum in primary cultures of rat hepatocytes. Exp. Cell Res. 167, 505-516 (1986).
28. Hughes, R.C. & Stamatoglou, S.C. Adhesive interactions and the metabolic activity of hepatocytes. J. Cell Sci. Suppl. 8, 273-291 (1987).
29. Freire, E. & Coelho-Sampaio, T. Self-assembly of laminin induced by acidic pH. J. Biol. Chem. 275, 817-822 (2000).
30. Nelson, C.M., Raghavan, S., Tan, J.L. & Chen, C.S. Degradation of micropatterned surfaces by cell-dependent and -independent processes. Langmuir 19, 1493-1499 (2003).
31. Angenendt, P., Glokler, J., Murphy, D., Lehrach, H. & Cahill, D.J. Toward optimized antibody microarrays: a comparison of current microarray support materials. Anal. Biochem. 309, 253-260 (2002).
32. Revzin, A. et al. Fabrication of poly(ethylene glycol) hydrogel microstructures using photolithography. Langmuir 17, 5440-5447 (2001).
33. Koh, W.G., Revzin, A. & Pishko, M.V. Poly(ethylene glycol) hydrogel microstructures encapsulating living cells. Langmuir 18, 2459-2462 (2002).
34. Kim, C.O., Hong, S.-Y., Kim, M., Park, S.-M. & Park, J.W. Modification of indium-tin oxide (ITO) glass with aziridine provides a surface of high amine density. J. Colloid Interface Sci. 277, 499-504 (2004).
35. Timofeev, E., Kochetkova, S.V., Mirzabekov, A.D. & Florentiev, V.L. Regioselective immobilization of short oligonucleotides to acrylic copolymer gels. Nucleic Acids Res. 24, 3142-3148 (1996).
36. Massia, S.P. & Hubbell, J.A. An RGD spacing of 440 nm is sufficient for integrin α V β 3-mediated fibroblast spreading and 140 nm for focal contact and stress fiber formation. J. Cell Biol. 114, 1089-1100 (1991).
37. Mooney, D. et al. Switching from differentiation to growth in hepatocytes: control by extracellular matrix. J. Cell. Physiol. 151, 497-505 (1992).
38. Pinkse, G.G. et al. Hepatocyte survival depends on β1-integrin-mediated attachment of hepatocytes to hepatic extracellular matrix. Liver Int. 24, 218-226 (2004).
39. Martinez-Hernandez, A. & Amenta, P.S. The hepatic extracellular matrix. I. Components and distribution in normal liver. Virchows Arch. A Pathol. Anat. Histopathol. 423, 1-11 (1993).
40. Stamatoglou, S.C., Enrich, C., Manson, M.M. & Hughes, R.C. Temporal changes in the expression and distribution of adhesion molecules during liver development and regeneration. J. Cell Biol. 116, 1507-1515 (1992).
41. Liu Tsang, V. Three-dimensional photopatterning of hydrogels containing living cells for hepatic tissue engineering. Ph.D. dissertation, University of California San Diego, La Jolla (2004).
42. Werb, Z., Tremble, P.M., Behrendtsen, O., Crowley, E. & Damsky, C.H. Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression. J. Cell Biol. 109, 877-889 (1989).
43. Pacifici, R. et al. Ligand binding to monocyte α5β1 integrin activates the α2β1 receptor via the α5 subunit cytoplasmic domain and protein kinase C. J. Immunol. 153, 2222-2233 (1994).
44. Diegelmann, R.F., Guzelian, P.S., Gay, R. & Gay, S. Collagen formation by the hepatocyte in primary monolayer culture and in vivo. Science 219, 1343-1345 (1983).
45. Fashena, S.J. & Thomas, S.M. Signalling by adhesion receptors. Nat. Cell Biol. 2, E225-E229 (2000).
46. Schwartz, M.A. & Ginsberg, M.H. Networks and crosstalk: integrin signalling spreads. Nat. Cell Biol. 4, E65-E68 (2002).
47. Pacifici, R. et al. Collagen-induced release of interteukin 1 from human blood mononuclear cells. Potentiation by fibronectin binding to the α5β1 integrin. J. Clin. Invest. 89, 61-67 (1992).
48. Kim, S., Harris, M. & Varner, J.A. Regulation of integrin αvβ3-mediated endothelial cell migration and angiogenesis by integrin α5β1 and protein kinase A. J. Biol. Chem. 275, 33920-33928 (2000).
49. Rathjen, J. et al. Directed differentiation of pluripotent cells to neural lineages: homogeneous formation and differentiation of a neurectoderm population. Development 129, 2649-2661 (2002).
50. Ying, Q.L., Stavridis, M., Griffiths, D., Li, M. & Smith, A. Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture. Nat. Biotechnol. 22, 183-186 (2003).
51. Ivanova, N.B. et al. A stem cell molecular signature. Science 298, 601-604 (2002).
52. Ramalho-Santos, M., Yoon, S., Matsuzaki, Y., Mulligan, R.C. & Melton, D.A. "Stemness": transcriptional profiling of embryonic and adult stem cells. Science 298, 597-600 (2002).
53. Kelly, D.L. & Rizzino, A. DNA microarray analyses of genes regulated during the differentiation of embryonic stem cells. Mol. Reprod. Dev. 56, 113-123 (2000).
54. Hamazaki, T. et al. Hepatic maturation in differentiating embryonic stem cells in vitro. FEBS Lett. 497, 15-19 (2001).
55. Yamada, T. et al. In vitro differentiation of embryonic stem cells into hepatocyte-like cells identified by cellular uptake of indocyanine green. Stem Cells 20, 146-154 (2002).
56. Chinzei, R. et al. Embryoid-body cells derived from a mouse embryonic stem cell line show differentiation into functional hepatocytes. Hepatology 36, 22-29 (2002).
57. Ishizaka, S. et al. Development of hepatocytes from ES cells after transfection with the HNF-3β gene. FASEB J. 16, 1444-1446 (2002).
58. Jones, E.A., Tosh, D., Wilson, D.I., Lindsay, S. & Forrester, L.M. Hepatic differentiation of murine embryonic stem cells. Exp. Cell Res. 272, 15-22 (2002).
59. Subramanian, S. & Srienc, F. Quantitative analysis of transient gene expression in mammalian cells using the green fluorescent protein. J. Biotechnol. 49, 137-151 (1996).
60. Arenkov, P. et al. Protein microchips: use for immunoassay and enzymatic reactions. Anal. Biochem. 278, 123-131 (2000).