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Volumn 18, Issue 10, 2013, Pages 1330-1337

A high-throughput-compatible 3D microtissue co-culture system for phenotypic RNAi screening applications

Author keywords

3D cell culture; Kif11; siRNA; tumor microtissue

Indexed keywords

KIF11 PROTEIN; KINESIN; MOLECULAR MOTOR; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

EID: 84887869938     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057113499071     Document Type: Article
Times cited : (47)

References (22)
  • 1
    • 33646343474 scopus 로고    scopus 로고
    • An shRNA Barcode Screen Provides Insight into Cancer Cell Vulnerability to MDM2 Inhibitors
    • Brummelkamp T. R., Fabius A. W., Mullenders J., et al. An shRNA Barcode Screen Provides Insight into Cancer Cell Vulnerability to MDM2 Inhibitors. Nat. Chem. Biol. 2006 ; 2: 202-206
    • (2006) Nat. Chem. Biol , vol.2 , pp. 202-206
    • Brummelkamp, T.R.1    Fabius, A.W.2    Mullenders, J.3
  • 2
    • 33646033137 scopus 로고    scopus 로고
    • A Lentiviral RNAi Library for Human and Mouse Genes Applied to an Arrayed Viral High-Content Screen
    • Moffat J., Grueneberg D. A., Yang X., et al. A Lentiviral RNAi Library for Human and Mouse Genes Applied to an Arrayed Viral High-Content Screen. Cell. 2006 ; 124: 1283-1298
    • (2006) Cell , vol.124 , pp. 1283-1298
    • Moffat, J.1    Grueneberg, D.A.2    Yang, X.3
  • 3
    • 34249828179 scopus 로고    scopus 로고
    • Regulators of Mitotic Arrest and Ceramide Metabolism Are Determinants of Sensitivity to Paclitaxel and Other Chemotherapeutic Drugs
    • Swanton C., Marani M., Pardo O., et al. Regulators of Mitotic Arrest and Ceramide Metabolism Are Determinants of Sensitivity to Paclitaxel and Other Chemotherapeutic Drugs. Cancer Cell. 2007 ; 11: 498-512
    • (2007) Cancer Cell , vol.11 , pp. 498-512
    • Swanton, C.1    Marani, M.2    Pardo, O.3
  • 4
    • 80055088241 scopus 로고    scopus 로고
    • Believe It or Not: How Much Can We Rely on Published Data on Potential Drug Targets?
    • Prinz F., Schlange T., Asadullah K.. Believe It or Not: How Much Can We Rely on Published Data on Potential Drug Targets?. Nat. Rev. Drug Discov. 2011 ; 10: 712
    • (2011) Nat. Rev. Drug Discov , vol.10 , pp. 712
    • Prinz, F.1    Schlange, T.2    Asadullah, K.3
  • 5
    • 78650012935 scopus 로고    scopus 로고
    • Invasive Three-Dimensional Organotypic Neoplasia from Multiple Normal Human Epithelia
    • Ridky T. W., Chow J. M., Wong D. J., et al. Invasive Three-Dimensional Organotypic Neoplasia from Multiple Normal Human Epithelia. Nat. Med. 2010 ; 16: 1450-1455
    • (2010) Nat. Med , vol.16 , pp. 1450-1455
    • Ridky, T.W.1    Chow, J.M.2    Wong, D.J.3
  • 6
    • 77957557692 scopus 로고    scopus 로고
    • Candidate Exome Capture Identifies Mutation of SDCCAG8 as the Cause of a Retinal-Renal Ciliopathy
    • Otto E. A., Hurd T. W., Airik R., et al. Candidate Exome Capture Identifies Mutation of SDCCAG8 as the Cause of a Retinal-Renal Ciliopathy. Nat. Genet. 2010 ; 42: 840-850
    • (2010) Nat. Genet , vol.42 , pp. 840-850
    • Otto, E.A.1    Hurd, T.W.2    Airik, R.3
  • 7
    • 83455236148 scopus 로고    scopus 로고
    • Towards Automated Production and Drug Sensitivity Testing Using Scaffold-Free Spherical Tumor Microtissues
    • Drewitz M., Helbling M., Fried N., et al. Towards Automated Production and Drug Sensitivity Testing Using Scaffold-Free Spherical Tumor Microtissues. Biotechnol. J. 2011 ; 6: 1488-1496
    • (2011) Biotechnol. J , vol.6 , pp. 1488-1496
    • Drewitz, M.1    Helbling, M.2    Fried, N.3
  • 8
    • 1642385430 scopus 로고    scopus 로고
    • Microscale Tissue Engineering Using Gravity-Enforced Cell Assembly
    • Kelm J. M., Fussenegger M.. Microscale Tissue Engineering Using Gravity-Enforced Cell Assembly. Trends Biotechnol. 2004 ; 22: 195-202
    • (2004) Trends Biotechnol , vol.22 , pp. 195-202
    • Kelm, J.M.1    Fussenegger, M.2
  • 9
    • 21244466378 scopus 로고    scopus 로고
    • VEGF Profiling and Angiogenesis in Human Microtissues
    • Kelm J. M., Diaz Sanchez-Bustamante C., Ehler E., et al. VEGF Profiling and Angiogenesis in Human Microtissues. J. Biotechnol. 2005 ; 118: 213-229
    • (2005) J. Biotechnol , vol.118 , pp. 213-229
    • Kelm, J.M.1    Diaz Sanchez-Bustamante, C.2    Ehler, E.3
  • 10
    • 82855168354 scopus 로고    scopus 로고
    • Tumor-Endothelial Cell Three-dimensional Spheroids: New Aspects to Enhance Radiation and Drug Therapeutics
    • Upreti M., Jamshidi-Parsian A., Koonce N. A., et al. Tumor-Endothelial Cell Three-dimensional Spheroids: New Aspects to Enhance Radiation and Drug Therapeutics. Transl. Oncol. 2011 ; 4: 365-376
    • (2011) Transl. Oncol , vol.4 , pp. 365-376
    • Upreti, M.1    Jamshidi-Parsian, A.2    Koonce, N.A.3
  • 11
    • 34247863920 scopus 로고    scopus 로고
    • PVHL and GSK3beta Are Components of a Primary Cilium-Maintenance Signalling Network
    • Thoma C. R., Frew I. J., Hoerner C. R., et al. pVHL and GSK3beta Are Components of a Primary Cilium-Maintenance Signalling Network. Nat. Cell Biol. 2007 ; 9: 588-595
    • (2007) Nat. Cell Biol , vol.9 , pp. 588-595
    • Thoma, C.R.1    Frew, I.J.2    Hoerner, C.R.3
  • 12
    • 55849136903 scopus 로고    scopus 로고
    • Global Protein Stability Profiling in Mammalian Cells
    • Yen H. C., Xu Q., Chou D. M., et al. Global Protein Stability Profiling in Mammalian Cells. Science. 2008 ; 322: 918-923
    • (2008) Science , vol.322 , pp. 918-923
    • Yen, H.C.1    Xu, Q.2    Chou, D.M.3
  • 13
    • 84863205849 scopus 로고    scopus 로고
    • NIH Image to ImageJ: 25 Years of Image Analysis
    • Schneider C. A., Rasband W. S., Eliceiri K. W.. NIH Image to ImageJ: 25 Years of Image Analysis. Nat. Methods. 2012 ; 9: 671-675
    • (2012) Nat. Methods , vol.9 , pp. 671-675
    • Schneider, C.A.1    Rasband, W.S.2    Eliceiri, K.W.3
  • 14
    • 68249112645 scopus 로고    scopus 로고
    • VHL Loss Causes Spindle Misorientation and Chromosome Instability
    • Thoma C. R., Toso A., Gutbrodt K. L., et al. VHL Loss Causes Spindle Misorientation and Chromosome Instability. Nat. Cell Biol. 2009 ; 11: 994-1001
    • (2009) Nat. Cell Biol , vol.11 , pp. 994-1001
    • Thoma, C.R.1    Toso, A.2    Gutbrodt, K.L.3
  • 15
    • 0033003760 scopus 로고    scopus 로고
    • A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays
    • Zhang J. H., Chung T. D., Oldenburg K. R.. A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays. J. Biomol. Screen. 1999 ; 4: 67-73
    • (1999) J. Biomol. Screen , vol.4 , pp. 67-73
    • Zhang, J.H.1    Chung, T.D.2    Oldenburg, K.R.3
  • 17
    • 84864285794 scopus 로고    scopus 로고
    • Tumour Micro-environment Elicits Innate Resistance to RAF Inhibitors through HGF Secretion
    • Straussman R., Morikawa T., Shee K., et al. Tumour Micro-environment Elicits Innate Resistance to RAF Inhibitors through HGF Secretion. Nature. 2012 ; 487: 500-504
    • (2012) Nature , vol.487 , pp. 500-504
    • Straussman, R.1    Morikawa, T.2    Shee, K.3
  • 18
    • 0029417238 scopus 로고
    • Phosphorylation by p34cdc2 Regulates Spindle Association of Human Eg5, a Kinesin-Related Motor Essential for Bipolar Spindle Formation in Vivo
    • Blangy A., Lane H. A., d'Herin P., et al. Phosphorylation by p34cdc2 Regulates Spindle Association of Human Eg5, a Kinesin-Related Motor Essential for Bipolar Spindle Formation In Vivo. Cell. 1995 ; 83: 1159-1169
    • (1995) Cell , vol.83 , pp. 1159-1169
    • Blangy, A.1    Lane, H.A.2    D'Herin, P.3
  • 19
    • 65949119123 scopus 로고    scopus 로고
    • Preferential Killing of Tetraploid Tumor Cells by Targeting the Mitotic Kinesin Eg5
    • Rello-Varona S., Vitale I., Kepp O., et al. Preferential Killing of Tetraploid Tumor Cells by Targeting the Mitotic Kinesin Eg5. Cell Cycle. 2009 ; 8: 1030-1035
    • (2009) Cell Cycle , vol.8 , pp. 1030-1035
    • Rello-Varona, S.1    Vitale, I.2    Kepp, O.3
  • 20
    • 22244459880 scopus 로고    scopus 로고
    • Induction of Apoptosis by an Inhibitor of the Mitotic Kinesin KSP Requires Both Activation of the Spindle Assembly Checkpoint and Mitotic Slippage
    • Tao W., South V. J., Zhang Y., et al. Induction of Apoptosis by an Inhibitor of the Mitotic Kinesin KSP Requires Both Activation of the Spindle Assembly Checkpoint and Mitotic Slippage. Cancer Cell. 2005 ; 8: 49-59
    • (2005) Cancer Cell , vol.8 , pp. 49-59
    • Tao, W.1    South, V.J.2    Zhang, Y.3
  • 22
    • 0033615357 scopus 로고    scopus 로고
    • Small Molecule Inhibitor of Mitotic Spindle Bipolarity Identified in a Phenotype-Based Screen
    • Mayer T. U., Kapoor T. M., Haggarty S. J., et al. Small Molecule Inhibitor of Mitotic Spindle Bipolarity Identified in a Phenotype-Based Screen. Science. 1999 ; 286: 971-974
    • (1999) Science , vol.286 , pp. 971-974
    • Mayer, T.U.1    Kapoor, T.M.2    Haggarty, S.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.