Heparin-binding domain of fibrin(ogen) binds growth factors and promotes tissue repair when incorporated within a synthetic matrix

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 12, 2013, Pages 4563-4568

  Martino, Mikaël M ^a   Briquez, Priscilla S ^a   Ranga, Adrian ^a   Lutolf, Matthias P ^a   Hubbell, Jeffrey A ^a,b  

^a Institute of Bioengineering (IBI)   (Switzerland)

^b EPFL   (Switzerland)

Author keywords

Angiogenesis; Hydrogel; Regenerative medicine

Indexed keywords

FIBRIN; FIBRINOGEN; FIBROBLAST GROWTH FACTOR; GROWTH FACTOR; HEPARIN BINDING PROTEIN; NEUROTROPHIN; PLATELET DERIVED GROWTH FACTOR; THROMBOPLASTIN; TRANSFORMING GROWTH FACTOR BETA; VASCULOTROPIN;

AMINO ACID SEQUENCE; ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; CONTROLLED STUDY; EXTRACELLULAR MATRIX; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; TISSUE REPAIR;

ANIMALS; BIOMIMETIC MATERIALS; DISEASE MODELS, ANIMAL; EXTRACELLULAR MATRIX; FIBRIN; FIBRINOGEN; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MICE; MICE, MUTANT STRAINS; PROTEIN BINDING; WOUND HEALING;

EID: 84875248854     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1221602110     Document Type: Article

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