FoxO proteins restrain osteoclastogenesis and bone resorption by attenuating H2O2 accumulation

Nature Communications

Volumn 5, Issue , 2014, Pages

  Bartell, Shoshana M ^a   Kim, Ha Neui ^a   Ambrogini, Elena ^a   Han, Li ^a   Iyer, Srividhya ^a   Ucer, S Serra ^a   Rabinovitch, Peter ^b   Jilka, Robert L ^a   Weinstein, Robert S ^a   Zhao, Haibo ^a   O'Brien, Charles A ^a   Manolagas, Stavros C ^a   Almeida, Maria ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALASE; COLONY STIMULATING FACTOR 1; ESTROGEN; HYDROGEN PEROXIDE; OSTEOCLAST DIFFERENTIATION FACTOR; PROTEIN KINASE B; TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR FKHRL1; TRANSCRIPTION FACTOR FOXO; TRANSCRIPTION FACTOR FOXO4; UNCLASSIFIED DRUG; FORKHEAD TRANSCRIPTION FACTOR; FOXO1 PROTEIN, MOUSE; PRIMER DNA; REACTIVE OXYGEN METABOLITE; TNFSF11 PROTEIN, MOUSE;

ADAPTATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME INHIBITION; FEMALE; MALE; MITOCHONDRION; MOUSE; NONHUMAN; OSTEOCLAST; OSTEOCLASTOGENESIS; OSTEOLYSIS; PROTEIN FUNCTION; TRANSCRIPTION TERMINATION; ANALYSIS OF VARIANCE; ANIMAL; CELL CULTURE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MICRO-COMPUTED TOMOGRAPHY; PATHOPHYSIOLOGY; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANALYSIS OF VARIANCE; ANIMALS; BLOTTING, WESTERN; BONE RESORPTION; CATALASE; CELLS, CULTURED; DNA PRIMERS; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HYDROGEN PEROXIDE; MICE; RANK LIGAND; REACTIVE OXYGEN SPECIES; REAL-TIME POLYMERASE CHAIN REACTION; X-RAY MICROTOMOGRAPHY;

EID: 84899783987     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms4773     Document Type: Article

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