Expanded granulocyte/monocyte compartment in myeloid-specific triple FoxO knockout increases oxidative stress and accelerates atherosclerosis in mice

Circulation Research

Volumn 112, Issue 7, 2013, Pages 992-1003

  Tsuchiya, Kyoichiro ^a   Westerterp, Marit ^b,c   Murphy, Andrew J ^b   Subramanian, Vidya ^b   Ferrante, Anthony W ^a,b   Tall, Alan R ^b   Accili, Domenico ^a  

^a New York Presbyterian Morgan Stanley Children's Hospital   (United States)

^b Howard Hughes Medical Institute   (United States)

^c UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

atherosclerosis; insulin resistance; macrophages; neutrophils; oxidative stress; stem cell

Indexed keywords

ACETYLCYSTEINE; FORKHEAD TRANSCRIPTION FACTOR; LOW DENSITY LIPOPROTEIN RECEPTOR; REACTIVE OXYGEN METABOLITE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATHEROSCLEROSIS; BONE MARROW CELL; CONTROLLED STUDY; GRANULOCYTE; IN VIVO STUDY; INSULIN SENSITIVITY; MONOCYTE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PHENOTYPE; PRIORITY JOURNAL;

ACETYLCYSTEINE; ANIMALS; ANTIOXIDANTS; APOPTOSIS; ATHEROSCLEROSIS; CYSTEINE; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; FREE RADICAL SCAVENGERS; HEMATOPOIETIC STEM CELLS; INSULIN; MACROPHAGES; MALE; MICE; MICE, KNOCKOUT; MONOCYTES; NEUTROPHILS; NITROGEN; OXIDATIVE STRESS; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TYROSINE;

EID: 84876415141     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.112.300749     Document Type: Article

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