The requirement for Cdc48/p97 in nuclear protein quality control degradation depends on the substrate and correlates with substrate insolubility

Journal of Cell Science

Volumn 127, Issue 9, 2014, Pages 1980-1991

  Gallagher, Pamela S ^a   Clowes Candadai, Sarah V ^a   Gardner, Richard G ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Cdc48; Misfolded protein; p97; Proteasome; Protein quality control; San1; Ubiquitin; VCP

Indexed keywords

ADENOSINE TRIPHOSPHATASE; CHAPERONE; ELONGATION FACTOR; HEAT SHOCK PROTEIN; NUCLEAR PROTEIN; PROTEIN P97; UBIQUITIN PROTEIN LIGASE; UBIQUITIN PROTEIN LIGASE SAN 1; UNCLASSIFIED DRUG; VALOSIN CONTAINING PROTEIN; CDC48 PROTEIN; CELL CYCLE PROTEIN; SACCHAROMYCES CEREVISIAE PROTEIN; SAN1 PROTEIN, S CEREVISIAE; UBIQUITIN;

AMINO ACID SEQUENCE; ARTICLE; CELL NUCLEUS INCLUSION BODY; CELL VIABILITY; FLUORESCENCE MICROSCOPY; GENE EXPRESSION SYSTEM; HYDROLYSIS; HYDROPHOBICITY; M PHASE CELL CYCLE CHECKPOINT; MICROTUBULE ASSEMBLY; MISSENSE MUTATION; MUTANT; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; POINT MUTATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; QUALITY CONTROL; SEDIMENTATION; SOLUBILITY; TEMPERATURE; UBIQUITINATION; UPREGULATION; GENETICS; METABOLISM; PROTEIN FOLDING; SACCHAROMYCES CEREVISIAE;

ADENOSINE TRIPHOSPHATASES; CELL CYCLE PROTEINS; PROTEIN FOLDING; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SOLUBILITY; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES;

EID: 84899728488     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.141838     Document Type: Article

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