Vacuole-creating protein in neurodegenerative diseases in humans

Neuroscience Letters

Volumn 343, Issue 2, 2003, Pages 77-80

  Mizuno, Yuji ^a   Hori, Seiji ^b   Kakizuka, Akira ^b   Okamoto, Koichi ^a  

^a GUNMA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

AAA family; Alzheimer's disease; Dementia; Motor neuron disease; Parkinson's disease; Ubiquitin; Vacuole creating protein

Indexed keywords

M PROTEIN; UBIQUITIN; UNCLASSIFIED DRUG; VACUOLE CREATING PROTEIN;

ALZHEIMER DISEASE; ARTICLE; BALLOON; CALCINOSIS; CELL DEATH; CELL VACUOLE; CLINICAL ARTICLE; CLINICAL OBSERVATION; CONTROLLED STUDY; CREUTZFELDT JAKOB DISEASE; DEMENTIA; HUMAN; IMMUNOHISTOCHEMISTRY; LEWY BODY; MOTOR NEURON DISEASE; NERVE CELL DEGENERATION; NERVE DEGENERATION; NEURITE; NEUROFIBRILLARY TANGLE; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FOLDING; REGULATORY MECHANISM; SENILE PLAQUE;

EID: 0037986563     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(03)00280-5     Document Type: Article

References (17)

1. Hirabayashi M., Inoue K., Tanaka K., Nakadate K., Ohsawa Y., Kamei Y., Popiel A.H., Sinohara A., Iwamatsu A., Kimura Y., Uchiyama Y., Hori S., Kakizuka A. VCP/p97 in abnormal protein aggregates, cytoplasmic vacuoles, and cell death, phenotypes relevant to neurodegeneration. Cell Death Differ. 8:2001;977-984.
2. Kakizuka A. Protein precipitation: a common etiology in neurodegenerative disorders? Trends Genet. 14:1998;396-402.
3. Love S., Saitoh T., Quijada S., Cole G.M., Terry R.D. Alz-50, ubiquitin and tau immunoreactivity of neurofibrillary tangles, Pick bodies and Lewy bodies. J. Neuropathol. Exp. Neurol. 47:1988;393-405.
4. Lowe J., Aldridge F., Lennox G., Doherty F., Jefferson D., Landon M., Mayer R.J. Inclusion bodies in motor cortex and brainstem of patients with motor neurone disease are detected by immunocytochemical localisation of ubiquitin. Neurosci. Lett. 105:1989;7-13.
5. Lowe J., Blanchard A., Morrell K., Lennox G., Reynolds L., Billett M., Landon M., Mayer R.J. Ubiquitin is a common factor in intermediate filament inclusion bodies of diverse type in man, including those of Parkinson's disease, Pick's disease, and Alzheimer's disease, as well as Rosenthal fibres in cerebellar astrocytomas, cytoplasmic bodies in muscle, and mallory bodies in alcoholic liver disease. J. Pathol. 155:1988;9-15.
6. Lowe J., Lennox G., Jefferson D., Morrell K., McQuire D., Gray T., Landon M., Doherty F.J., Mayer R.J. A filamentous inclusion body within anterior horn neurones in motor neurone disease defined by immunocytochemical localisation of ubiquitin. Neurosci. Lett. 94:1988;203-210.
7. Müller J.M.M., Meyer H.H., Ruhrberg C., Stamp G.W., Warren G., Shima D.T. The mouse p97 (CDC48) gene. J. Biol. Chem. 274:1999;10154-10162.
8. Okamoto K. Temporal lobe pathology in patients with amyotrophic lateral sclerosis. Neuropathology. 18:1998;222-227.
9. Okamoto K., Hirai S., Amari M., Sakurai A. Electron micrograph of ubiquitin-positive intraneuronal inclusions in the extra-motor cortices in patients with amyotrophic lateral sclerosis. Neuropathology. 16:1996;112-116.
10. Okamoto K., Hirai S., Iizuka T., Yanagisawa T., Watanabe M. Reexamination of granulovacuolar degeneration. Acta Neuropathol. 82:1991;340-345.
11. Okamoto K., Hirai S., Yamazaki T., Sun X., Nakazato Y. New ubiquitin-positive intraneuronal inclusions in the extra-motor cortices in patients with amyotrophic lateral sclerosis. Neurosci. Lett. 129:1991;233-236.
12. Okamoto K., Murakami N., Kusaka H., Yoshida M., Hashizume Y., Nakazato Y., Matsubara E., Hirai S. Ubiquitin-positive intraneuronal inclusions in the extramotor cortices of presenile dementia patients with motor neuron disease. J. Neurol. 239:1992;426-430.
13. Price D.L. New order from neurological disorders. Nature. 399:1999;A3-A5.
14. Sakurai A., Okamoto K., Yaguchi M., Fujita Y., Mizuno Y., Nakazato Y., Gonatas N.K. Pathology of the inferior olivary nucleus in patients with multiple system atrophy. Acta Neuropathol. 103:2002;550-554.
15. Takahashi H., Wakabayashi K. The cellular pathology of Parkinson's disease. Neuropathology. 21:2001;315-322.
16. Wakabayashi K., Engelender S., Tanaka Y., Yoshimoto M., Mori F., Tsuji S., Ross C.A., Takahashi H. Immunocytochemical localization of synphilin-1, an a-synuclein-associated protein, in neurodegenerative disorders. Acta Neuropathol. 103:2002;209-214.
17. Wakabayashi K., Hayashi S., Kakita A., Yamada M., Toyoshima Y., Yoshimoto M., Takahashi H. Accumulation of alpha-synuclein/NACP is a cytopathological feature common to Lewy body disease and multiple system atrophy. Acta Neuropathol. 96:1998;445-452.