A HECT Domain E3 Enzyme Assembles Novel Polyubiquitin Chains

Journal of Biological Chemistry

Volumn 276, Issue 23, 2001, Pages 19871-19878

  You, Jianxin ^b   Pickart, Cecile M ^a  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; CELLS; ENZYMES; POLYPEPTIDES; PURIFICATION;

ERYTHROID CELLS;

BIOCHEMISTRY;

19S PROTEASOME; 26S PROTEASOME; AMINO ACID; COMPLEMENTARY DNA; ENZYME; HYBRID PROTEIN; LYSINE; POLYPEPTIDE; POLYUBIQUITIN; PROTEASOME; PROTEIN; PROTEIN KIAA10; PROTEIN RPN1; PROTEIN SUBUNIT; PROTEIN UBCH5A; RECOMBINANT PROTEIN; UBIQUITIN CONJUGATING ENZYME; UBIQUITIN PROTEIN ISOPEPTIDE LIGASE; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG; BIOPOLYMER; ESTER; LIGASE; THIOL DERIVATIVE; UBIQUITIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CHEMICAL REACTION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME BINDING; ENZYME PURIFICATION; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; ENZYME SUBUNIT; HOMOLOGOUS TO E6 AP CARBOXYL TERMINUS DOMAIN; HUMAN; IN VIVO STUDY; MEDICAL LITERATURE; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN INTERACTION; PUBLICATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; UBIQUITINATION; CHEMISTRY; METABOLISM; PROTEIN BINDING;

ANIMALIA;

BIOPOLYMERS; CATALYSIS; ESTERS; LIGASES; POLYUBIQUITIN; PROTEIN BINDING; RECOMBINANT PROTEINS; SULFHYDRYL COMPOUNDS; UBIQUITIN-PROTEIN LIGASES; UBIQUITINS;

EID: 0035827707     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M100034200     Document Type: Article

References (46)

1. Hershko, A., and Ciechanover, A. (1998) Annu. Rev. Biochem. 67, 425-479
2. Chau, V., Tobias, J. W., Bachmair, A., Marriott, D., Ecker, D. J., Gonda, D. K., and Varshavsky, A. (1989) Science 243, 1576-1583
3. Gregori, L., Poosch, M. S., Cousins, G., and Chau, V. (1990) J. Biol. Chem. 265, 8354-8357
4. Finley, D., Sadis, S., Monia, B. P., Boucher, P., Ecker, D. J., Crooke, S. T., and Chau, V. (1994) Mol. Cell. Biol. 14, 5501-5509
5. Thrower, J. S., Hoffman, L., Rechsteiner, M., and Pickart, C. M. (2000) EMBO J. 19, 94-102
6. Deshaies, R. J. (1999) Annu. Rev. Cell Dev. Biol. 15, 435-467
7. Huibregtse, J. M., Scheffner, M., Beaudenon, S., and Howley, P. M. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 2563-2567
8. Scheffner, M., Nuber, U., and Huibregtse, J. M. (1995) Nature 373, 81-83
9. Scheffner, M., Huibregtse, J. M., Vierstra, R. D., and Howley, P. M. (1993) Cell 75, 495-505
10. Huibregtse, J. M., Scheffner, M., and Howley, P. M. (1993) Mol. Cell. Biol. 13, 4918-4927
11. Pickart, C. M. (2000) Trends Biochem. Sci. 25, 544-548
12. Arnason, T., and Ellison, M. J. (1994) Mol. Cell. Biol. 14, 7876-7883
13. Spence, J., Sadis, S., Haas, A. L., and Finley, D. (1995) Mol. Cell. Biol. 15, 1265-1273
14. Galan, J., and Haguenauer-Tsapis, R. (1997) EMBO J. 16, 5847-5854
15. Spence, J., Gali, R. R., Dittmar, G., Sherman, F., Karin, M., and Finley, D. (2000) Cell 102, 67-76
16. Johnson, E. S., Ma, P. C., Ota, I. M., and Varshavsky, A. (1995) J. Biol. Chem. 270, 17442-17456
17. Liu, Z., Haas, A. L., Diaz, L. A., Conrad, C. A., and Giudice, G. J. (1996) J. Biol. Chem. 271, 2817-2822
18. Baboshina, O. V., and Haas, A. L. (1996) J. Biol. Chem. 271, 2823-2831
19. Koegl, M., Hoppe, T., Schlenker, S., Ulrich, H. D., Mayer, T. U., and Jentsch, S. (1999) Cell 96, 635-644
20. Mastrandrea, L. D., You, J., Niles, E. G., and Pickart, C. M. (1999) J. Biol. Chem. 274, 27299-27306
21. Hershko, A., Heller, H., Elias, S., and Ciechanover, A. (1983) J. Biol. Chem. 258, 8206-8214
22. Pickart, C. M., and Vella, A. T. (1988) J. Biol. Chem. 263, 12028-12035
23. Laemmli, U. K. (1970) Nature 227, 680-685
24. Ausubel, F. M., Brent, R., Kingston, R. E., Moore, D. D., Seidman, J. G., Smith, J. A., Struhl, K., Albright, L. M., Coen, D. M., Varki, A., and Chanda, V. B. (eds) (1994) Current Protocols in Molecular Biology, John Wiley & Sons, Inc., New York
25. Scheffner, M., Huibregtse, J. M., and Howley, P. M. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 8797-8801
26. Haldeman, M. T., Xia, G., Kasperek, E. M., and Pickart, C. M. (1997) Biochemistry 36, 10526-10537
27. Nomura, N., Miyajima, N., Sazuka, T., Tanaka, A., Kawarabayasi, Y., Sato, S., Nagase, T., Seki, N., Ishikawa, K., and Tabata, S. (1994) DNA Res. 1, 27-35
28. You, J., Cohen, R. E., and Pickart, C. M. (1999) BioTechniques 27, 950-954
29. Hodgins, R., Gwozd, C., Arnason, T., Cummings, M., and Ellison, M. J. (1996) J. Biol. Chem. 271, 28766-28771
30. Patra, A. K., Mukhopadhyay, R., Mukhiga, R., Krishnan, A., Garg, L. C., and Panda, A. K. (2000) Protein Expression Purif 18, 182-192
31. Huang, L., Kinnucan, E., Wang, G., Beaudenon, S., Howley, P. M., Huibregtse, J. M., and Pavletich, N. P. (1999) Science 286, 1321-1326
32. Siepmann, T. J., and Haas, A. L. (1996) FASEB. J. 10, 1402 (abstr.)
33. Pickart, C. M., Haldeman, M. T., Kasperek, E. M., and Chen, Z. (1992) J. Biol. Chem. 267, 14418-14423
34. Schwarz, S. E., Rosa, J. L., and Scheffner, M. (1998) J. Biol. Chem. 273, 12148-12154
35. Tongaonkar, P., Chen, L., Lambertson, D., Ko, B., and Madura, K. (2000) Mol. Cell. Biol. 20, 4691-4698
36. Xie, Y., and Varshavsky, A. (2000) Proe. Natl. Acad. Sci. U. S. A. 97, 2497-2502
37. Huang, Y., Baker, R. T., and Fischer-Vize, J. A. (1995) Science 270, 1828-1831
38. Aoki, T., Okada, N., Ishida, M., Yogosawa, S., Makino, Y., and Tamura, T. (1999) Biochem. Biophys. Res. Commun. 261, 911-916
39. Makino, Y., Yoshida, T., Yogosawa, S., Tanaka, K., Muramatsu, M., and Tamura, T. A. (1999) Genes Cells 4, 529-539
40. Ferrell, K., Wilkinson, C. R. M., Dubiel, W., and Gordon, C. (2000) Trends Biochem. Sci. 25, 83-88
41. Staub, O., Dho, S., Henry, P. C., Correa, J., Ishikawa, T., McGlade, J., and Rotin, D. (1996) EMBO J. 15, 2371-2380
42. Huibregtse, J. M., Yang, J. C., and Beaudenon, S. L. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 3656-3661
43. Qiu, L., Joazeiro, C., Fang, N., Wang, H. Y., Elly, C., Altman, Y., Fang, D., Hunter, T., and Liu, Y. C. (2000) J. Biol. Chem. 275, 35734-35737
44. Kao, W. H., Beaudenon, S. L., Talis, A. L., Huibregtse, J. M., and Howley, P. M. (2000) J. Virol. 74, 6408-6417
45. Verma, R., Chen, S., Feldman, R., Schieltz, D., Yates, J., Dohmen, J., and Deshaies, R. J. (2000) Mol. Biol. Cell 11, 3425-3439
46. Kleijnen, M. F., Shih, A. H., Zhou, P., Kumar, S., Soccio, R. E., Kedersha, N. L., Gill, G., and Howley, P. (2000) Mol. Cell 6, 409-419