The Cdc48 protein and its cofactor Vms1 are involved in Cdc13 protein degradation

Journal of Biological Chemistry

Volumn 287, Issue 32, 2012, Pages 26788-26795

  Baek, Guem Hee ^a   Cheng, Haili ^a   Kim, Ikjin ^a   Rao, Hai ^a  

^a Mays Cancer Center at UT Health San Antonio   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOPHAGY; BINDING PROTEINS; BIOLOGICAL FUNCTIONS; COFACTORS; PROTEASOMES; PROTEIN DEGRADATION; TELOMERES; YEAST PROTEINS;

DEGRADATION;

PROTEINS;

ADENOSINE TRIPHOSPHATASE; BINDING PROTEIN; CDC13 PROTEIN; CDC48 PROTEIN; PROTEASOME; SINGLE STRANDED DNA BINDING PROTEIN; UNCLASSIFIED DRUG; VIRUS PROTEIN; VMS1 PROTEIN;

ARTICLE; AUTOPHAGY; BIOLOGICAL FUNCTIONS; CONTROLLED STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; PROTEIN METABOLISM; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; REGULATORY MECHANISM; UBIQUITINATION;

ADENOSINE TRIPHOSPHATASES; AUTOPHAGY; CARRIER PROTEINS; CELL CYCLE PROTEINS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEOLYSIS; SACCHAROMYCES CEREVISIAE PROTEINS; SIROLIMUS; TELOMERE-BINDING PROTEINS;

EID: 84864565210     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.351825     Document Type: Article

References (24)

1. Meyer, H., Bug, M., and Bremer, S. (2012) Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system. Nat. Cell Biol. 14, 117-123
2. Stolz, A., Hilt, W., Buchberger, A., and Wolf, D. H. (2011) Cdc48: a power machine in protein degradation. Trends Biochem. Sci. 36, 515-523
3. Ramanathan, H. N., and Ye, Y. (2011) Revoking the cellular license to replicate: yet another AAA assignment. Mol. Cell 44, 3-4
4. Baek, G. H., Kim, I., and Rao, H. (2011) The Cdc48 ATPase modulates the interaction between two proteolytic factors, Ufd2 and Rad23. Proc. Natl. Acad. Sci. U.S.A. 108, 13558-13563
5. Buchberger, A. (2010) Control of ubiquitin conjugation by Cdc48 and its cofactors. Subcell. Biochem. 54, 17-30
6. Heo, J. M., Livnat-Levanon, N., Taylor, E. B., Jones, K. T., Dephoure, N., Ring, J., Xie, J., Brodsky, J. L., Madeo, F., Gygi, S. P., Ashrafi, K., Glickman, M. H., and Rutter J. (2010) A stress-responsive system for mitochondrial protein degradation. Mol. Cell 40, 465-480
7. Tran, J. R., Tomsic, L. R., and Brodsky, J. L. (2011) A Cdc48p-associated factor modulates endoplasmic reticulum-associated degradation, cell stress, and ubiquitinated protein homeostasis. J. Biol. Chem. 286, 5744-5755
8. Pinto, A. R., Li, H., Nicholls, C., and Liu, J. P. (2011) Telomere protein complexes and interactions with telomerase in telomere maintenance. Front. Biosci. 16, 187-207
9. Tseng, S. F., Shen, Z. J., Tsai, H. J., Lin, Y. H., and Teng, S. C. (2009) Rapid Cdc13 turnover and telomere length homeostasis are controlled by Cdk1-mediated phosphorylation of Cdc13. Nucleic Acids Res. 37, 3602-3611
10. Yang, Z., and Klionsky, D. J. (2010) Eaten alive: a history of macroautophagy. Nat. Cell Biol. 12, 814-822
11. Lynch-Day, M. A., and Klionsky, D. J. (2010) The Cvt pathway as a model for selective autophagy. FEBS Lett. 584, 1359-1366
12. Nakatogawa, H., Suzuki, K., Kamada, Y., and Ohsumi, Y. (2009) Dynamics and diversity in autophagy mechanisms: lessons from yeast. Nat. Rev. Mol. Cell Biol. 10, 458-467
13. Gavin, A. C., Bösche, M., Krause, R., Grandi, P., Marzioch, M., Bauer, A., Schultz, J., Rick, J. M., Michon, A. M., Cruciat, C. M., Remor, M., Höfert, C., Schelder, M., Brajenovic, M., Ruffner, H., Merino, A., Klein, K., Hudak, M., Dickson, D., Rudi, T., Gnau, V., Bauch, A., Bastuck, S., Huhse, B., Leutwein, C., Heurtier, M. A., Copley, R. R., Edelmann, A., Querfurth, E., Rybin, V., Drewes, G., Raida, M., Bouwmeester, T., Bork, P., Seraphin, B., Kuster, B., Neubauer, G., and Superti-Furga, G. (2002) Functional organization of the yeast proteome by systematic analysis of protein complexes. Nature 415, 141-147 (Pubitemid 34059510)
14. Ho, Y., Gruhler, A., Heilbut, A., Bader, G. D., Moore, L., Adams, S. L., Millar, A., Taylor, P., Bennett, K., Boutilier, K., Yang, L., Wolting, C., Donaldson, I., Schandorff, S., Shewnarane, J., Vo, M., Taggart, J., Goudreault, M., Muskat, B., Alfarano, C., Dewar, D., Lin, Z., Michalickova, K., Willems, A. R., Sassi, H., Nielsen, P. A., Rasmussen, K. J., Andersen, J. R., Johansen, L. E., Hansen, L. H., Jespersen, H., Podtelejnikov, A., Nielsen, E., Crawford, J., Poulsen, V., Sørensen, B. D., Matthiesen, J., Hendrickson, R. C., Gleeson, F., Pawson, T., Moran, M. F., Durocher, D., Mann, M., Hogue, C. W., Figeys, D., and Tyers, M. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature 415, 180-183 (Pubitemid 34059520)
15. Krogan, N. J., Cagney, G., Yu, H., Zhong, G., Guo, X., Ignatchenko, A., Li, J., Pu, S., Datta, N., Tikuisis, A. P., Punna, T., Peregrín-Alvarez, J. M., Shales, M., Zhang, X., Davey, M., Robinson, M. D., Paccanaro, A., Bray, J. E., Sheung, A., Beattie, B., Richards, D. P., Canadien, V., Lalev, A., Mena, F., Wong, P., Starostine, A., Canete, M. M., Vlasblom, J., Wu, S., Orsi, C., Collins, S. R., Chandran, S., Haw, R., Rilstone, J. J., Gandi, K., Thompson, N. J., Musso, G., St Onge, P., Ghanny, S., Lam, M. H., Butland, G., Altaf-Ul, A. M., Kanaya, S., Shilatifard, A., O'Shea, E., Weissman, J. S., Ingles, C. J., Hughes, T. R., Parkinson, J., Gerstein, M., Wodak, S. J., Emili, A., and Greenblatt, J. F. (2006) Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature 440, 637-643
16. Liu, C., van Dyk, D., Xu, P., Choe, V., Pan, H., Peng, J., Andrews, B., and Rao, H. (2010) Ubiquitin chain elongation enzyme Ufd2 regulates a subset of Doa10 substrates. J. Biol. Chem. 285, 10265-10272
17. Kirkin, V., and Dikic, I. (2011) Ubiquitin networks in cancer. Curr. Opin. Genet. Dev. 21, 21-28
18. Liu, C., van Dyk, D., Choe, V., Yan, J., Majumder, S., Costanzo, M., Bao, X., Boone, C., Huo, K., Winey, M., Fisk, H., Andrews, B., and Rao, H. (2011) Ubiquitin ligase Ufd2 is required for efficient degradation of Mps1 kinase. J. Biol. Chem. 286, 43660-43667
19. Kraft, C., Deplazes, A., Sohrmann, M., and Peter, M. (2008) Mature ribosomes are selectively degraded upon starvation by an autophagy pathway requiring the Ubp3p/Bre5p ubiquitin protease. Nat. Cell Biol. 10, 602-610 (Pubitemid 351627380)
20. Watts, G. D., Wymer, J., Kovach, M. J., Mehta, S. G., Mumm, S., Darvish, D., Pestronk, A., Whyte, M. P., and Kimonis, V. E. (2004) Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein. Nat. Genet. 36, 377-381 (Pubitemid 38437260)
21. Badadani, M., Nalbandian A., Watts, G. D., Vesa, J., Kitazawa, M., Su, H., Tanaja, J., Dec, E., Wallace, D. C., Mukherjee, J., Caiozzo, V., Warman, M., and Kimonis, V. E. (2010) VCP-associated inclusion body myopathy and Paget disease of bone knock-in mouse model exhibits tissue pathology typical of human disease. PLoS ONE 5, e13183
22. Kim, I., Ahn, J., Liu, C., Tanabe, K., Apodaca, J., Suzuki, T., and Rao, H. (2006) The Png1-Rad23 complex regulates glycoprotein turnover. J. Cell Biol. 172, 211-219 (Pubitemid 43112968)
23. Nair, U., Thumm, M., Klionsky, D. J., and Krick, R. (2011) GFP-Atg8 protease protection as a tool to monitor autophagosome biogenesis. Autophagy 7, 1546-1550
24. Ravid, T., Kreft, S. G., and Hochstrasser, M. (2006) Membrane and soluble substrates of the Doa10 ubiquitin ligase are degraded by distinct pathways. EMBO J. 25, 533-543 (Pubitemid 43237660)