The AAA-ATPase Cdc48/p97 regulates spindle disassembly at the end of mitosis

Cell

Volumn 115, Issue 3, 2003, Pages 355-367

  Cao, Kan ^a,b   Nakajima, Reiko ^a   Meyer, Hemmo H ^c   Zheng, Yixian ^a,b  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c ETH ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; ADENOSINE TRIPHOSPHATASE; CELL CYCLE PROTEIN; CELL CYCLE PROTEIN 48; CHAPERONE; PROTEIN KINASE; PROTEIN NPL4; PROTEIN UFD1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CELL NUCLEUS; CELL POLARITY; CHROMOSOME; CONTROLLED STUDY; EGG; ENZYME ACTIVITY; FEMALE; GENETIC ANALYSIS; INTERPHASE; MALE; MICROTUBULE ASSEMBLY; MITOSIS; MITOSIS SPINDLE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN INTERACTION; SEQUENCE HOMOLOGY; XENOPUS;

ANIMALIA;

EID: 0344845397     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(03)00815-8     Document Type: Article

References (58)

1. Bardin A.J., Amon A. MEN and SIN. what is the difference? Nat. Rev. Mol. Cell Biol. 2:2001;815-823.
2. Bays W.B., Hampton R.Y. Cdc48-Ufd1-Npl4. stuck in the middle with Ub Curr. Biol. 12:2002;R366-R371.
3. Bays W.B., Wilhovsky S.K., Goradia A., Hodgkiss-Harlow K., Hampton R.Y. HRD4/NPL4 is required for the proteasomal processing of ubiquitinated ER proteins. Mol. Biol. Cell. 12:2001;4114-4128.
4. Belmont L.D., Hyman A.A., Sawin K.E., Mitchison T.J. Real-time visualization of cell cycle-dependent changes in microtubule dynamics in cytoplasmic extracts. Cell. 62:1990;579-589.
5. Blangy A., Lane H.A., d'Herin P., Harper M., Kress M., Nigg E.A. Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle assembly in vivo. Cell. 83:1995;1159-1169.
6. ufd1/NPL4 chaperone (segregase) in ERAD of OLE1 and other substrates. EMBO J. 21:2002;615-621.
7. Breugel M.V., Drechsel D., Hyman A.A. Stu2p, the budding yeast member of the conserved Dis1/XMAP215 family of microtubule-associated proteins is a plus end-binding microtubule destabilizer. J. Cell Biol. 161:2003;359-369.
8. Carazo-Salas R.E., Guarguaglini G., Gruss O.J., Segref A., Karsenti E., Mattaj I.W. Generation of GTP-bound Ran by RCC1 is required for chromatin-induced mitotic spindle formation. Nature. 400:1999;178-181.
9. Carazo-Salas R.E., Gruss O.J., Mattaj I.W., Karsenti E. RanGTP coordinates the regulation of microtubule nucleation and dynamics during mitotic spindle assembly. Nat. Cell Biol. 3:2001;228-234.
10. Cassimeris L. Accessory protein regulation of microtubule dynamics throughout the cell cycle. Curr. Opin. Cell Biol. 11:1999;134-141.
11. Cheng L., Hunke L., Hardy C.F.J. Cell cycle regulation of the Saccharomyces cerevisiae polo-like kinase Cdc5p. Mol. Cell. Biol. 18:1998;7360-7370.
12. Dai R.M., Li C.H. Valosin-containing protein is a multi-ubiquitin chain-targeting factor required in ubiquitin-proteasome degradation. Nat. Cell Biol. 3:2001;740-744.
13. Desai A., Mitchison T.J. Microtubule polymerization dynamics. Annu. Rev. Cell Dev. Biol. 13:1998;83-117.
14. Desai A., Verma S., Mitchison T., Walczak C.E. Kin I kinesins are microtubule-destabilizing enzymes. Cell. 1:1999;69-78.
15. Felix M.A., Pines J., Hunt T., Karsenti E. A post-ribosomal supernatant from activated Xenopus eggs that displays post-translationally regulated oscillation of its cdc2+ mitotic kinase activity. EMBO J. 8:1989;3059-3069.
16. Frohlich K.U., Fries H., Rudiger M., Erdmann R., Botstein D., Mecke D. Yeast cell cycle protein CDC48p shows full-length homology to the mammalian protein VCP and is a member of a protein family involved in secretion, peroxisome formation, and gene expression. J. Cell Biol. 114:1991;443-453.
17. Gliksman N.R., Parsons S.F., Salmon E.D. Okadaic acid induces interphase to mitotic-like microtubule dynamic instability by inactivating rescue. J. Cell Biol. 119:1992;1271-1276.
18. Gliksman N.R., Skibbens R.V., Salmon E.D. How the transition frequencies of microtubule dynamic instability (nucleation, catastrophe, and rescue) regulate microtubule dynamics in interphase and mitosis. analysis using a Monte Carlo computer simulation Mol. Biol. Cell. 4:1993;1035-1050.
19. Gruss O.J., Carazo-Salas R.E., Schatz C.A., Guarguaglini G., Kast J., Wilm M., Bot N.L., Vernos I., Karsenti E., Mattaj I.W. Ran induces spindle assembly by reversing the inhibitory effect of importin α on TPX2 activity. Cell. 104:2001;83-92.
20. Gruss O.J., Wittmann M., Yokoyama H., Pepperkok R., Kufer T., Sillje H., Karsenti E., Mattaj I.W., Vernos I. Chromosome-induced microtubule assembly mediated by TPX2 is required for spindle formation in HeLa cells. Nat. Cell Biol. 4:2002;871-879.
21. Hetzer M., Meyer H.H., Walther T.C., Cortes-Bilbao D., Warren G., Mattaj I.W. Distinct AAA-ATPase p97 complexes function in discrete steps of nuclear assembly. Nat. Cell Biol. 3:2001;1086-1091.
22. Hitchcock A.L., Krebber H., Frietze S., Lin A., Latterich M., Silver P.A. The conserved Npl4 protein complex mediates proteasome-dependent membrane-bound transcription factor activation. Mol. Biol. Cell. 12:2001;3226-3241.
23. Hoyt M.A. Exit from mitosis. spindle pole power Cell. 102:2000;267-270.
24. Hyman A., Drechsel D., Kellogg D., Salser S., Sawin K., Steffen P., Wordeman L., Mitchison T. Preparation of modified tubulins. Meth. Enzymol. 196:1991;478-487.
25. Jarosch E., Geiss-Friedlander R., Meusser B., Walter J., Sommer T. Protein dislocation from the endoplasmic reticulum-pulling out the suspect. Traffic. 3:2002;530-536. a.
26. Jarosch E., Taxis C., Volkwein C., Bordallo J., Finley D., Wolf D.H., Sommer T. Protein dislocation from the ER requires polyubiquitination and the AAA-ATPase Cdc48. Nat. Cell Biol. 4:2002;134-139. b.
27. Jensen S., Geymonat M., Johnston L.H. Mitotic exit. delaying the end without FEAR Curr. Biol. 12:2002;R221-R223.
28. Juang Y., Huang J., Peters J., Mclaughlin M.E., Tai C., Pellman D. APC-mediated proteolysis of Ase1 and the morphogenesis of the mitotic spindle. Science. 275:1997;1311-1314.
29. Kalab P., Pu R., Dasso M. The Ran GTPase regulates mitotic spindle assembly. Curr. Biol. 9:1999;481-484.
30. Kalab P., Weis K., Heald R. Visualization of a Ran-GTP gradient in interphase and mitotic Xenopus egg extracts. Science. 295:2002;2452-2456.
31. Latterich M., Frohlich K.U., Schekman R. Membrane fusion and the cell cycle. Cdc48p participates in the fusion of ER membranes Cell. 82:1995;885-893.
32. Lupas A.N., Martin J. AAA proteins. Curr. Opin. Struct. Biol. 12:2002;746-753.
33. McNally F.J. Modulation of microtubule dynamics during the cell cycle. Curr. Opin. Cell Biol. 8:1996;23-29.
34. Meyer H.H., Shorter J.G., Seemann J., Pappin D., Warren G. A complex of mammalian Ufd1 and Npl4 links the AAA-ATPase, p97, to ubiquitin and nuclear transport pathways. EMBO J. 19:2000;2181-2192.
35. Meyer H.H., Wang Y., Warren G. Direct binding of ubiquitin conjugates by the mammalian p97 adaptor complexes, p47 and Ufd1-Npl4. EMBO J. 21:2002;5645-5652.
36. Mitchison T.J., Kirschner M.W. Isolation of mammalian centrosomes. Meth. Enzymol. 134:1986;261-268.
37. Moir D., Stewart S.E., Osmond B.C., Botstein D. Cold sensitive cell-division-cycle mutants of yeast. isolation, properties, and pseudoreversion studies Genetics. 100:1982;547-563.
38. Murray A.W. Cell cycle extracts. Methods Cell Biol. 36:1991;581-605.
39. Murray A.W., Kirschner M.W. Cyclin synthesis drives the early embryonic cell cycle. Nature. 339:1989;275-280.
40. Nigg E.A. Polo-like kinases. positive regulators of cell division from start to finish Curr. Opin. Cell Biol. 10:1998;776-783.
41. Pellman D., Bagget M., Tu H., Fink G.R. Two microtubule-associated proteins required for anaphase spindle movement in Saccharomyces cerevisiae. J. Cell Biol. 130:1995;1373-1385.
42. Qian Y.-W., Erikson E., Maller J. Mitotic effects of a constitutively active mutant of the Xenopus polo-like kinase Plx1. Mol. Cell. Biol. 19:1999;8625-8635.
43. Rabinovich E., Kerem A., Frohlich K.U., Diamant N., Bar-Nun S. AAA-ATPase p97/Cdc48, a cytosolic chaperone required for endoplasmic reticulum-associated protein degradation. Mol. Cell. Biol. 22:2002;626-634.
44. Rape M., Hoppe T., Gorr I., Kalcocay M., Richly H., Jentsch S. Mobilization of processed, membrane-tethered SPT23 transcription factor by CDC48/Ufd1/Npl4, a ubiquitin-selective chaperone. Cell. 107:2001;667-677.
45. Schatz C.A., Santarella R., Hoenger A., Karsenti E., Mattaj I.W., Gruss O.J., Carazo-Salas R.E. Importin α-regulated nucleation of microtubules by TPX2. EMBO J. 22:2003;2060-2070.
46. Shirasu-Hiza M., Coughlin P., Mitchison T. Identification of XMAP215 as a microtubule-destabilizing factor in Xenopus egg extract by biochemical purification. J. Cell Biol. 161:2003;349-358.
47. Song S., Lee K. A novel function of Saccharomyces cerevisiae CDC5 in cytokinesis. J. Cell Biol. 152:2001;451-469.
48. Stegmeier F., Visintin R., Amon A. Separase, Polo kinase, the kinetochore protein Slk19, and Spo12 function in a network that controls Cdc14 localization during early anaphase. Cell. 108:2002;207-220.
49. Tsai B., Ye Y., Rapoport T.A. Retro-translocation of proteins from the endoplasmic reticulum into the cytosol. Nat. Rev. Mol. Cell Biol. 3:2002;246-255.
50. Tsai M.-Y., Wiese C., Cao K., Martin O.C., Donovan P.J., Ruderman J.V., Prigent C., Zheng Y. A Ran signalling pathway mediated by the mitotic kinase Aurora A in spindle assembly. Nat. Cell Biol. 5:2003;242-248.
51. Verde F., Labbe J.C., Doree M., Karsenti E. Regulation of microtubule dynamics by cdc2 protein kinase in cell-free extracts of Xenopus eggs. Nature. 343:1990;233-238.
52. Verde F., Dogterom M., Stelzer E., Karsenti E., Leibler S. Control of microtubule dynamics and length by cyclin A- and cyclin B-dependent kinases in Xenopus egg extracts. J. Cell Biol. 118:1992;1097-1108.
53. Walczak C., Verma S., Mitchison T. XCTK2. a kinesin-related protein that promotes mitotic spindle assembly in xenopus laevis egg extracts J. Cell Biol. 136:1997;859-870.
54. Wilde A., Zheng Y. Stimulation of microtubule aster formation and spindle assembly by the small GTPase Ran. Science. 284:1999;1359-1362.
55. Wilde A., Lizarraga S.B., Zhang L., Wiese C., Gliksman N.R., Walczak C.E., Zheng Y. Ran stimulates spindle assembly by changing microtubule dynamics and the balance of motor activities. Nat. Cell Biol. 3:2001;221-227.
56. Wittmann T., Wilm M., Karsenti E., Vernos I. TPX2, A novel Xenopus MAP involved in spindle pole organization. J. Cell Biol. 149:2000;1405-1418.
57. Ye Y., Meyer H.H., Rapopport T.A. The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol. Nature. 414:2001;652-656.
58. Zhai Y., Kronebusch P.J., Simon K.M., Borisy G.G. Microtubule dynamics at the G2/M transition. abrupt breakdown of cytoplasmic microtubules at nuclear envelope breakdown and implications for spindle morphogenesis J. Cell Biol. 135:1996;201-214.