Polyhydroxylated fullerene attenuates oxidative stress-induced apoptosis via a fortifying Nrf2-regulated cellular antioxidant defence system

International Journal of Nanomedicine

Volumn 9, Issue 1, 2014, Pages 2073-2087

  Ye, Shefang ^a   Chen, Min ^a   Jiang, Yuanqin ^a,b   Chen, Mingliang ^c   Zhou, Tong ^a   Wang, Yange ^a   Hou, Zhenqing ^a   Ren, Lei ^a  

^a XIAMEN UNIVERSITY   (China)

^b THE FIRST AFFILIATED HOSPITAL OF XIAMEN UNIVERSITY   (China)

^c Key Laboratory of Marine Genetic Resources of Fujian Province   (China)

Author keywords

A549 cells; Cytoprotection; Fullerenol; Nrf2; Oxidative stress

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; ANTIOXIDANT; FULLERENOL DERIVATIVE; GAMMA GLUTAMATE CYSTEINE LIGASE; GLUTAMATE CYSTEINE LIGASE; HEME OXYGENASE 1; HYDROGEN PEROXIDE; JANUS KINASE; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; OXIDOREDUCTASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUININE) 1; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; FULLERENE DERIVATIVE; NFE2L2 PROTEIN, HUMAN; REACTIVE OXYGEN METABOLITE;

ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL DEATH; CELL PROTECTION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; LUNG ALVEOLUS EPITHELIUM; OXIDATIVE STRESS; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION; CELL LINE; CHEMISTRY; CYTOLOGY; DOSE RESPONSE; DRUG EFFECTS; HYDROXYLATION; MATERIALS TESTING; METABOLISM; PHYSIOLOGY; RESPIRATORY TRACT MUCOSA;

ANTIOXIDANTS; APOPTOSIS; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; FULLERENES; HUMANS; HYDROXYLATION; MATERIALS TESTING; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; RESPIRATORY MUCOSA;

EID: 84899726082     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S56973     Document Type: Article

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