Cinnamaldehyde enhances Nrf2 nuclear translocation to upregulate phase II detoxifying enzyme expression in HepG2 cells

Journal of Agricultural and Food Chemistry

Volumn 59, Issue 9, 2011, Pages 5164-5171

  Huang, Tzou Chi ^a   Chung, Yu Ling ^a   Wu, Mei Li ^a   Chuang, Show Mei ^b  

^a NATIONAL PINGTUNG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^b NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

Author keywords

Chemopreventive agent; Cinnamaldehyde; Glutamate cysteine ligase; Glutathione; Glutathione S transferase; Phase II detoxifying enzyme

Indexed keywords

CHEMOPREVENTIVE AGENTS; CINNAMALDEHYDE; GLUTAMATE-CYSTEINE LIGASE; GLUTATHIONE S-TRANSFERASE; GLUTATHIONES; PHASE II DETOXIFYING ENZYME;

ALDEHYDES; AMINO ACIDS; CATALYSTS; ELECTROPHORETIC MOBILITY; ENZYMES; GENE EXPRESSION; NUCLEIC ACIDS; RNA; SIGNALING;

ENZYME INHIBITION;

ACROLEIN; CINNAMALDEHYDE; DRUG DERIVATIVE; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE TRANSFERASE; PLANT EXTRACT; TRANSCRIPTION FACTOR NRF2;

ARTICLE; CELL NUCLEUS; CELL STRAIN HEPG2; CHEMISTRY; CINNAMOMUM; DRUG DETOXIFICATION; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; UPREGULATION;

ACROLEIN; CELL NUCLEUS; CINNAMOMUM; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUTAMATE-CYSTEINE LIGASE; GLUTATHIONE TRANSFERASE; HEP G2 CELLS; HUMANS; METABOLIC DETOXICATION, PHASE II; NF-E2-RELATED FACTOR 2; PLANT EXTRACTS; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 79955677645     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf200579h     Document Type: Article

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