SOD Activity of carboxyfullerenes predicts their neuroprotective efficacy: a structure-activity study

Nanomedicine: Nanotechnology, Biology, and Medicine

Volumn 4, Issue 4, 2008, Pages 283-294

  Ali, Sameh Saad ^a   Hardt, Joshua I ^b   Dugan, Laura L ^a,c  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Carboxyfullerenes; Neuroprotection; SOD mimetics; Superoxide

Indexed keywords

BIOCHEMISTRY; BIODIVERSITY; FULLERENES; MOLECULAR GRAPHICS; PLANTS (BOTANY);

ASPARTATE RECEPTORS; BIOPHYSICAL CHARACTERISTICS; CARBOXYFULLERENES; CARBOXYL GROUPS; MIMETICS; NEUROPROTECTION; NEUROTOXICITY; SOD ACTIVITIES; SOD MIMETICS; STRUCTURE-ACTIVITY RELATIONSHIPS; SUPEROXIDE; SUPEROXIDE DISMUTASE; SUPEROXIDE RADICAL ANIONS; SUPEROXIDE RADICALS; TISSUE INJURIES;

OXYGEN;

CARBOXYL GROUP; CARBOXYLFULLERENE; FULLERENE DERIVATIVE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; SUPEROXIDE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; CORRELATIONAL STUDY; DIPOLE; DRUG BINDING; DRUG EFFICACY; ENZYME ACTIVITY; MOLECULAR MODEL; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PREDICTION; STRUCTURE ACTIVITY RELATION;

ANIMALS; BIOMIMETIC MATERIALS; CELLS, CULTURED; CEREBRAL CORTEX; FREE RADICAL SCAVENGERS; FULLERENES; MICE; MODELS, MOLECULAR; MOLECULAR STRUCTURE; N-METHYLASPARTATE; NEURONS; NEUROPROTECTIVE AGENTS; PROTEIN BINDING; RECEPTORS, N-METHYL-D-ASPARTATE; STRUCTURE-ACTIVITY RELATIONSHIP; SUPEROXIDE DISMUTASE; SUPEROXIDES;

EID: 55949103187     PISSN: 15499634     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nano.2008.05.003     Document Type: Article

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