Exploring the influence of egcg on the b-sheet-rich oligomers of human islet amyloid polypeptide (hiapp and identifying its possible binding sites from molecular dynamics simulation

PLoS ONE

Volumn 9, Issue 4, 2014, Pages

  Wang, Qianqian ^a   Guo, Jingjing ^a,b   Jiao, Pingzu ^a   Liu, Huanxiang ^a,b   Yao, Xiaojun ^b,c  

^a LANZHOU UNIVERSITY   (China)

^b LANZHOU UNIVERSITY   (China)

^c MACAU UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Macao)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; AMYLIN; EPIGALLOCATECHIN GALLATE; HUMAN ISLET AMYLOID POLYPEPTIDE [1-47]; ISOLEUCINE; LEUCINE; OLIGOMER; PHENYLALANINE; TYROSINE; UNCLASSIFIED DRUG; CATECHIN; PROTEIN BINDING;

ANALYTICAL PARAMETERS; ARTICLE; BETA SHEET; BINDING KINETICS; BINDING SITE; FREE ENERGY LANDSCAPE; MOLECULAR DYNAMICS; PROTEIN CONFORMATION; PROTEIN SECONDARY STRUCTURE; PROTEIN TARGETING; ALGORITHM; ANALOGS AND DERIVATIVES; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; HUMAN; METABOLISM; PROTEIN MULTIMERIZATION; PROTEIN TERTIARY STRUCTURE;

ALGORITHMS; BINDING SITES; CATECHIN; HUMANS; ISLET AMYLOID POLYPEPTIDE; MOLECULAR DYNAMICS SIMULATION; MOLECULAR STRUCTURE; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY;

EID: 84899690875     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0094796     Document Type: Article

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