Toward the molecular mechanism(s) by which EGCG treatment remodels mature amyloid fibrils

Journal of the American Chemical Society

Volumn 135, Issue 20, 2013, Pages 7503-7510

  Palhano, Fernando L ^a,b   Lee, Jiyong ^a   Grimster, Neil P ^a   Kelly, Jeffery W ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOIDOGENIC PROTEINS; EPIGALLOCATECHIN-3-GALLATE; HYDROPHOBIC BINDING; MOLECULAR MECHANISM; PARKINSON'S DISEASE; POST-TRANSLATIONAL MODIFICATIONS; PROTEIN MISFOLDING; REMODELING ACTIVITY;

FUNCTIONAL GROUPS; GLYCOPROTEINS; OXIDATION;

PROTEINS;

AMYLOID; EPIGALLOCATECHIN GALLATE;

ARTICLE; BINDING SITE; DRUG MECHANISM; DRUG PROTEIN BINDING; DRUG STRUCTURE; IN VITRO STUDY;

AMYLOID; CATECHIN; HEK293 CELLS; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE;

EID: 84878234966     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja3115696     Document Type: Article

References (26)

1. Chiti, F.; Dobson, C. M. Annu. Rev. Biochem. 2006, 75, 333
2. Bulawa, C. E.; Connelly, S.; Devit, M.; Wang, L.; Weigel, C.; Fleming, J. A.; Packman, J.; Powers, E. T.; Wiseman, R. L.; Foss, T. R.; Wilson, I. A.; Kelly, J. W.; Labaudiniere, R. Proc. Natl. Acad. Sci. U.S.A. 2012, 109, 9629
3. Palladini, G.; Merlini, G. Haematologica 2009, 94, 1044
4. Ehrnhoefer, D. E.; Duennwald, M.; Markovic, P.; Wacker, J. L.; Engemann, S.; Roark, M.; Legleiter, J.; Marsh, J. L.; Thompson, L. M.; Lindquist, S.; Muchowski, P. J.; Wanker, E. E. Hum. Mol. Genet. 2006, 15, 2743
5. Ehrnhoefer, D. E.; Bieschke, J.; Boeddrich, A.; Herbst, M.; Masino, L.; Lurz, R.; Engemann, S.; Pastore, A.; Wanker, E. E. Nat. Struct. Mol. Biol. 2008, 15, 558
6. Bieschke, J.; Russ, J.; Friedrich, R. P.; Ehrnhoefer, D. E.; Wobst, H.; Neugebauer, K.; Wanker, E. E. Proc. Natl. Acad. Sci. U.S.A. 2010, 107, 7710
7. Du, D.; Murray, A. N.; Cohen, E.; Kim, H. E.; Simkovsky, R.; Dillin, A.; Kelly, J. W. Biochemistry 2011, 50, 1607
8. Serio, T. R.; Cashikar, A. G.; Moslehi, J. J.; Kowal, A. S.; Lindquist, S. L. Methods Enzymol. 1999, 309, 649
9. Parge, H. E.; Hallewell, R. A.; Tainer, J. A. Proc. Natl. Acad. Sci. U.S.A. 1992, 89, 6109
10. Paoletti, F.; Mocali, A. Methods Enzymol. 1990, 186, 209
11. Paz, M. A.; Fluckiger, R.; Boak, A.; Kagan, H. M.; Gallop, P. M. J. Biol. Chem. 1991, 266, 689
12. Bohm, G.; Muhr, R.; Jaenicke, R. Protein Eng. 1992, 5, 191
13. Sang, S.; Lee, M. J.; Hou, Z.; Ho, C. T.; Yang, C. S. J. Agric. Food Chem. 2005, 53, 9478
14. Murray, A. N.; Solomon, J. P.; Wang, Y. J.; Balch, W. E.; Kelly, J. W. Protein Sci. 2010, 19, 836
15. Suzuki, Y.; Brender, J. R.; Hartman, K.; Ramamoorthy, A.; Marsh, E. N. Biochemistry 2012, 51, 8154
16. Ishii, T.; Mori, T.; Tanaka, T.; Mizuno, D.; Yamaji, R.; Kumazawa, S.; Nakayama, T.; Akagawa, M. Free Radical Biol. Med. 2008, 45, 1384
17. Elbling, L.; Weiss, R. M.; Teufelhofer, O.; Uhl, M.; Knasmueller, S.; Schulte-Hermann, R.; Berger, W.; Micksche, M. FASEB J. 2005, 19, 807
18. Williams, A. D.; Shivaprasad, S.; Wetzel, R. J. Mol. Biol. 2006, 357, 1283
19. Popovych, N.; Brender, J. R.; Soong, R.; Vivekanandan, S.; Hartman, K.; Basrur, V.; Macdonald, P. M.; Ramamoorthy, A. J. Phys. Chem. B 2012, 116, 3650
20. Cao, P.; Raleigh, D. P. Biochemistry 2012, 51, 2670
21. Engel, M. F.; vandenAkker, C. C.; Schleeger, M.; Velikov, K. P.; Koenderink, G. H.; Bonn, M. J. Am. Chem. Soc. 2012, 134, 14781
22. Lopez del Amo, J. M.; Fink, U.; Dasari, M.; Grelle, G.; Wanker, E. E.; Bieschke, J.; Reif, B. J. Mol. Biol. 2012, 421, 517
23. Maurer-Stroh, S.; Debulpaep, M.; Kuemmerer, N.; Lopez de la Paz, M.; Martins, I. C.; Reumers, J.; Morris, K. L.; Copland, A.; Serpell, L.; Serrano, L.; Schymkowitz, J. W.; Rousseau, F. Nature Methods 2010, 7, 237
24. Azevedo, E. P.; Guimaraes-Costa, A. B.; Torezani, G. S.; Braga, C. A.; Palhano, F. L.; Kelly, J. W.; Saraiva, E. M.; Foguel, D. J. Biol. Chem. 2012, 287, 37206
25. Carulla, N.; Caddy, G. L.; Hall, D. R.; Zurdo, J.; Gairi, M.; Feliz, M.; Giralt, E.; Robinson, C. V.; Dobson, C. M. Nature 2005, 436, 554
26. Xue, W. F.; Hellewell, A. L.; Gosal, W. S.; Homans, S. W.; Hewitt, E. W.; Radford, S. E. J. Biol. Chem. 2009, 284, 34272