-
1
-
-
57349160569
-
Cell cycle-dependent regulation of extra-adrenal glucocorticoid synthesis in murine intestinal epithelial cells
-
doi: 10.1096/fj.08-114157
-
Atanasov AG, Leiser D, Roesselet C, Noti M, Corazza N, Schoonjans K, Brunner T. 2008. Cell cycle-dependent regulation of extra-adrenal glucocorticoid synthesis in murine intestinal epithelial cells. FASEB Journal 22:4117-4125. doi: 10.1096/fj.08-114157.
-
(2008)
FASEB Journal
, vol.22
, pp. 4117-4125
-
-
Atanasov, A.G.1
Leiser, D.2
Roesselet, C.3
Noti, M.4
Corazza, N.5
Schoonjans, K.6
Brunner, T.7
-
2
-
-
80051542339
-
Faulty initiation of proteoglycan synthesis causes cardiac and joint defects
-
doi: 10.1016/j.ajhg.2011.05.021
-
Baasanjav S, Al-Gazali L, Hashiguchi T, Mizumoto S, Fischer B, Horn D, Seelow D, Ali BR, Aziz SA, Langer R, Saleh AA, Becker C, Nurnberg G, Cantagrel V, Gleeson JG, Gomez D, Michel JB, Stricker S, Lindner TH, Nurnberg P, Sugahara K, Mundlos S, Hoffmann K. 2011. Faulty initiation of proteoglycan synthesis causes cardiac and joint defects. American Journal of Human Genetics 89:15-27. doi: 10.1016/j.ajhg.2011.05.021.
-
(2011)
American Journal of Human Genetics
, vol.89
, pp. 15-27
-
-
Baasanjav, S.1
Al-Gazali, L.2
Hashiguchi, T.3
Mizumoto, S.4
Fischer, B.5
Horn, D.6
Seelow, D.7
Ali, B.R.8
Aziz, S.A.9
Langer, R.10
Saleh, A.A.11
Becker, C.12
Nurnberg, G.13
Cantagrel, V.14
Gleeson, J.G.15
Gomez, D.16
Michel, J.B.17
Stricker, S.18
Lindner, T.H.19
Nurnberg, P.20
Sugahara, K.21
Mundlos, S.22
Hoffmann, K.23
more..
-
3
-
-
84879722826
-
Detection and quantification of endoplasmic reticulum stress in living cells using the fluorescent compound, Thioflavin T
-
doi: 10.1016/j. bbamcr.2013.05.020
-
Beriault DR, Werstuck GH. 2013. Detection and quantification of endoplasmic reticulum stress in living cells using the fluorescent compound, Thioflavin T. Biochimica et Biophysica Acta 1833:2293-2301. doi: 10.1016/j. bbamcr.2013.05.020.
-
(2013)
Biochimica Et Biophysica Acta
, vol.1833
, pp. 2293-2301
-
-
Beriault, D.R.1
Werstuck, G.H.2
-
4
-
-
34547946030
-
Feedback regulation of p38 activity via ATF2 is essential for survival of embryonic liver cells
-
doi: 10.1101/gad.430207
-
Breitwieser W, Lyons S, Flenniken AM, Ashton G, Bruder G, Willington M, Lacaud G, Kouskoff V, Jones N. 2007. Feedback regulation of p38 activity via ATF2 is essential for survival of embryonic liver cells. Genes & Development 21:2069-2082. doi: 10.1101/gad.430207.
-
(2007)
Genes & Development
, vol.21
, pp. 2069-2082
-
-
Breitwieser, W.1
Lyons, S.2
Flenniken, A.M.3
Ashton, G.4
Bruder, G.5
Willington, M.6
Lacaud, G.7
Kouskoff, V.8
Jones, N.9
-
5
-
-
34047117344
-
ATF2 is required for amino acid-regulated transcription by orchestrating specific histone acetylation
-
doi: 10.1093/nar/gkm038
-
Bruhat A, Cherasse Y, Maurin AC, Breitwieser W, Parry L, Deval C, Jones N, Jousse C, Fafournoux P. 2007. ATF2 is required for amino acid-regulated transcription by orchestrating specific histone acetylation. Nucleic Acids Research 35:1312-1321. doi: 10.1093/nar/gkm038.
-
(2007)
Nucleic Acids Research
, vol.35
, pp. 1312-1321
-
-
Bruhat, A.1
Cherasse, Y.2
Maurin, A.C.3
Breitwieser, W.4
Parry, L.5
Deval, C.6
Jones, N.7
Jousse, C.8
Fafournoux, P.9
-
6
-
-
29944445793
-
Identification of mitogen-activated protein kinase signaling pathways that confer resistance to endoplasmic reticulum stress in Saccharymyces cerevisiae
-
doi: 10.1158/1541-7786. MCR-05-0181
-
Chen Y, Feldman DE, Deng C, Brown JA, De Giacomo AF, Gaw AF, Shi G, Le QT, Brown JM, Koong AC. 2005. Identification of mitogen-activated protein kinase signaling pathways that confer resistance to endoplasmic reticulum stress in Saccharymyces cerevisiae. Molecular Cancer Research 3:669-677. doi: 10.1158/1541-7786. MCR-05-0181.
-
(2005)
Molecular Cancer Research
, vol.3
, pp. 669-677
-
-
Chen, Y.1
Feldman, D.E.2
Deng, C.3
Brown, J.A.4
de Giacomo, A.F.5
Gaw, A.F.6
Shi, G.7
Le, Q.T.8
Brown, J.M.9
Koong, A.C.10
-
7
-
-
84857919534
-
Genome-wide analysis of hepatic LRH-1 reveals a promoter binding preference and suggests a role in regulating genes of lipid metabolism in concert with FXR
-
doi: 10.1186/1471-2164-13-51
-
Chong HK, Biesinger J, Seo Y-K, Xie X, Osborne TF. 2012. Genome-wide analysis of hepatic LRH-1 reveals a promoter binding preference and suggests a role in regulating genes of lipid metabolism in concert with FXR. BMC Genomics 13:15. doi: 10.1186/1471-2164-13-51.
-
(2012)
BMC Genomics
, vol.13
, pp. 15
-
-
Chong, H.K.1
Biesinger, J.2
Seo, Y.-K.3
Xie, X.4
Osborne, T.F.5
-
8
-
-
84867317004
-
Identification of novel NRF2-regulated genes by ChIP-Seq: Influence on retinoid X receptor alpha
-
doi: 10.1093/nar/gks409
-
Chorley BN, Campbell MR, Wang X, Karaca M, Sambandan D, Bangura F, Xue P, Pi J, Kleeberger SR, Bell DA. 2012. Identification of novel NRF2-regulated genes by ChIP-Seq: influence on retinoid X receptor alpha. Nucleic Acids Research 40:7416-7429. doi: 10.1093/nar/gks409.
-
(2012)
Nucleic Acids Research
, vol.40
, pp. 7416-7429
-
-
Chorley, B.N.1
Campbell, M.R.2
Wang, X.3
Karaca, M.4
Sambandan, D.5
Bangura, F.6
Xue, P.7
Pi, J.8
Kleeberger, S.R.9
Bell, D.A.10
-
9
-
-
79955550445
-
A user's guide to the encyclopedia of DNA elements (ENCODE)
-
ENCODE Project Consortium, doi: 10.1371/journal.pbio.1001046
-
ENCODE Project Consortium. 2011. A user's guide to the encyclopedia of DNA elements (ENCODE). PLOS Biology 9:e1001046. doi: 10.1371/journal.pbio.1001046.
-
(2011)
PLOS Biology
, vol.9
-
-
-
10
-
-
23744437996
-
C-Jun N-terminal kinase (JNK) is required for survival and proliferation of B-lymphoma cells
-
doi: 10.1182/blood-2004-10-3819
-
Gururajan M, Chui R, Karuppannan AK, Ke J, Jennings CD, Bondada S. 2005. C-Jun N-terminal kinase (JNK) is required for survival and proliferation of B-lymphoma cells. Blood 206:1382-1391. doi: 10.1182/blood-2004-10-3819.
-
(2005)
Blood
, vol.206
, pp. 1382-1391
-
-
Gururajan, M.1
Chui, R.2
Karuppannan, A.K.3
Ke, J.4
Jennings, C.D.5
Bondada, S.6
-
11
-
-
84869210796
-
Hyperactivity of the Ero1a oxidase elicits endoplasmic reticulum stress but no broad antioxidant response
-
doi: 10.1074/jbc.M112.405050
-
Hansen HG, Schmidt JD, Soltoft CL, Ramming T, Geertz-Hansen HM, Christensen B, Sorensen ES, Juncker AS, Appenzeller-Herzog C, Ellgaard L. 2012. Hyperactivity of the Ero1a oxidase elicits endoplasmic reticulum stress but no broad antioxidant response. The Journal of Biological Chemistry 287:39513-39523. doi: 10.1074/jbc.M112.405050.
-
(2012)
The Journal of Biological Chemistry
, vol.287
, pp. 39513-39523
-
-
Hansen, H.G.1
Schmidt, J.D.2
Soltoft, C.L.3
Ramming, T.4
Geertz-Hansen, H.M.5
Christensen, B.6
Sorensen, E.S.7
Juncker, A.S.8
Appenzeller-Herzog, C.9
Ellgaard, L.10
-
12
-
-
0038757747
-
The activation of c-Jun NH2-terminal kinase (JNK) by DNA-damaging agents serves to promote drug resistance via activating transcription factor 2 (ATF2)-dependent enhanced DNA repair
-
doi: 10.1074/jbc.M210992200
-
Hayakawa J, Depatie C, Ohmichi M, Mercola D. 2003. The activation of c-Jun NH2-terminal kinase (JNK) by DNA-damaging agents serves to promote drug resistance via activating transcription factor 2 (ATF2)-dependent enhanced DNA repair. The Journal of Biological Chemistry 278:20582-20592. doi: 10.1074/jbc.M210992200.
-
(2003)
The Journal of Biological Chemistry
, vol.278
, pp. 20582-20592
-
-
Hayakawa, J.1
Depatie, C.2
Ohmichi, M.3
Mercola, D.4
-
13
-
-
77952567987
-
Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities
-
doi: 10.1016/j.molcel.2010.05.004
-
Heinz S, Benner C, Spann N, Bertolino E, Lin YC, Laslo P, Cheng JX, Murre C, Singh H, Glass CK. 2010. Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. Molecular Cell 38:576-589. doi: 10.1016/j.molcel.2010.05.004.
-
(2010)
Molecular Cell
, vol.38
, pp. 576-589
-
-
Heinz, S.1
Benner, C.2
Spann, N.3
Bertolino, E.4
Lin, Y.C.5
Laslo, P.6
Cheng, J.X.7
Murre, C.8
Singh, H.9
Glass, C.K.10
-
14
-
-
33947246606
-
Expression profiling of liver receptor homologue 1 (LRH-1) in mouse tissues using tissue microarray
-
doi: 10.1007/s10735-007-9077-6
-
Higashiyama H, Kinoshita M, Asano S. 2007. Expression profiling of liver receptor homologue 1 (LRH-1) in mouse tissues using tissue microarray. Journal of Molecular Histology 38:45-52. doi: 10.1007/s10735-007-9077-6.
-
(2007)
Journal of Molecular Histology
, vol.38
, pp. 45-52
-
-
Higashiyama, H.1
Kinoshita, M.2
Asano, S.3
-
15
-
-
79953886306
-
Thermogenic activation induces FGF21 expression and release in brown adipose tissue
-
doi: 10.1074/jbc.M110.215889
-
Hondares E, Iglesias R, Giralt A, Gonzalez FJ, Giralt M, Mampel T, Villarroya F. 2011. Thermogenic activation induces FGF21 expression and release in brown adipose tissue. The Journal of Biological Chemistry 286:12983-12990. doi: 10.1074/jbc.M110.215889.
-
(2011)
The Journal of Biological Chemistry
, vol.286
, pp. 12983-12990
-
-
Hondares, E.1
Iglesias, R.2
Giralt, A.3
Gonzalez, F.J.4
Giralt, M.5
Mampel, T.6
Villarroya, F.7
-
16
-
-
10344253840
-
Critical role of endogenous Akt/IAPs and MEK1/ERK pathways in counteracting endoplasmic reticulum stress-induced cell death
-
doi: 10.1074/jbc.M407700200
-
Hu P, Han Z, Couvillon AD, Exton JH. 2004. Critical role of endogenous Akt/IAPs and MEK1/ERK pathways in counteracting endoplasmic reticulum stress-induced cell death. Journal of Biological Chemistry 279:49420-49429. doi: 10.1074/jbc.M407700200.
-
(2004)
Journal of Biological Chemistry
, vol.279
, pp. 49420-49429
-
-
Hu, P.1
Han, Z.2
Couvillon, A.D.3
Exton, J.H.4
-
17
-
-
80054003242
-
Chipster: User-friendly analysis software for microarray and other high-throughput data
-
doi: 10.1186/1471-2164-12-507
-
Kallio MA, Tuimala JT, Hupponen T, Klemela P, Gentile M, Scheinin I, Koski M, Kaki J, Korpelainen EI. 2011. Chipster: user-friendly analysis software for microarray and other high-throughput data. BMC Genomics 12:507. doi: 10.1186/1471-2164-12-507.
-
(2011)
BMC Genomics
, vol.12
, pp. 507
-
-
Kallio, M.A.1
Tuimala, J.T.2
Hupponen, T.3
Klemela, P.4
Gentile, M.5
Scheinin, I.6
Koski, M.7
Kaki, J.8
Korpelainen, E.I.9
-
18
-
-
0034604540
-
Selective activation of p38 MAPK cascade and mitotic arrest caused by low level oxidative stress
-
doi: 10.1074/jbc.C000308200
-
Kurata S. 2000. Selective activation of p38 MAPK cascade and mitotic arrest caused by low level oxidative stress. The Journal of Biological Chemistry 275:23413-23416. doi: 10.1074/jbc.C000308200.
-
(2000)
The Journal of Biological Chemistry
, vol.275
, pp. 23413-23416
-
-
Kurata, S.1
-
19
-
-
79959560633
-
A nuclear-receptordependent phosphatidylcholine pathway with antidiabetic effects
-
doi: 10.1038/nature10111
-
Lee JM, Lee YK, Mamrosh JL, Busby SA, Griffin PR, Pathak MC, Ortlund EA, Moore DD. 2011. A nuclear-receptordependent phosphatidylcholine pathway with antidiabetic effects. Nature 474:506-510. doi: 10.1038/nature10111.
-
(2011)
Nature
, vol.474
, pp. 506-510
-
-
Lee, J.M.1
Lee, Y.K.2
Mamrosh, J.L.3
Busby, S.A.4
Griffin, P.R.5
Pathak, M.C.6
Ortlund, E.A.7
Moore, D.D.8
-
20
-
-
44649202231
-
Liver receptor homolog-1 regulates bile acid homeostasis but is not essential for feedback regulation of bile acid synthesis
-
doi: 10.1210/me.2007-0565
-
Lee YK, Schmidt DR, Cummins CL, Choi M, Peng L, Zhang Y, Goodwin B, Hammer RE, Mangelsdorf DJ, Kliewer SA. 2008. Liver receptor homolog-1 regulates bile acid homeostasis but is not essential for feedback regulation of bile acid synthesis. Molecular Endocrinology 22:1345-1356. doi: 10.1210/me.2007-0565.
-
(2008)
Molecular Endocrinology
, vol.22
, pp. 1345-1356
-
-
Lee, Y.K.1
Schmidt, D.R.2
Cummins, C.L.3
Choi, M.4
Peng, L.5
Zhang, Y.6
Goodwin, B.7
Hammer, R.E.8
Mangelsdorf, D.J.9
Kliewer, S.A.10
-
21
-
-
41749108854
-
Endoplasmic reticulum stress in disease pathogenesis
-
doi: 10.1146/annurev.pathmechdis.3.121806.151434
-
Lin JH, Walter P, Yen TS. 2008. Endoplasmic reticulum stress in disease pathogenesis. Annual Review of Pathology 3:399-425. doi: 10.1146/annurev.pathmechdis.3.121806.151434.
-
(2008)
Annual Review of Pathology
, vol.3
, pp. 399-425
-
-
Lin, J.H.1
Walter, P.2
Yen, T.S.3
-
22
-
-
0029034251
-
ATF-2 contains a phosphorylation-dependent transcriptional activation domain
-
Livingstone C, Patel G, Jones N. 1995. ATF-2 contains a phosphorylation-dependent transcriptional activation domain. The EMBO Journal 14:1785-1797.
-
(1995)
The EMBO Journal
, vol.14
, pp. 1785-1797
-
-
Livingstone, C.1
Patel, G.2
Jones, N.3
-
23
-
-
34250378403
-
A protocol for rapid generation of recombinant adenovirus using the AdEasy system
-
doi: 10.1038/nprot.2007.135
-
Luo J, Deng Z-L, Luo X, Tang N, Song W-X, Chen J, Sharff KA, Luu HH, Haydon RC, Kinzler KW, Vogelstein B, He T-C. 2007. A protocol for rapid generation of recombinant adenovirus using the AdEasy system. Nature Protocols 2:1236-1247. doi: 10.1038/nprot.2007.135.
-
(2007)
Nature Protocols
, vol.2
, pp. 1236-1247
-
-
Luo, J.1
Deng, Z.-L.2
Luo, X.3
Tang, N.4
Song, W.-X.5
Chen, J.6
Sharff, K.A.7
Luu, H.H.8
Haydon, R.C.9
Kinzler, K.W.10
Vogelstein, B.11
He, T.-C.12
-
24
-
-
57349140727
-
Expression of the transcriptional repressor ATF3 in gonadotrophs is regulated by Egr-1, CREB, and ATF2 after gonadotropin-releasing hormone receptor stimulation
-
doi: 10.1210/en.2008-0251
-
Mayer SI, Dexheimer V, Nishida E, Kitajima S, Thiel G. 2008. Expression of the transcriptional repressor ATF3 in gonadotrophs is regulated by Egr-1, CREB, and ATF2 after gonadotropin-releasing hormone receptor stimulation. Endocrinology 149:6311-6325. doi: 10.1210/en.2008-0251.
-
(2008)
Endocrinology
, vol.149
, pp. 6311-6325
-
-
Mayer, S.I.1
Dexheimer, V.2
Nishida, E.3
Kitajima, S.4
Thiel, G.5
-
25
-
-
84883474258
-
Diverse stresses dramatically alter genome-wide p53 binding and transactivation landscape in human cancer cells
-
doi: 10.1093/nar/gkt504
-
Menendez D, Nguyen T-A, Freudenberg JM, Mathew VJ, Anderson CW, Jothi R, Resnick MA. 2013. Diverse stresses dramatically alter genome-wide p53 binding and transactivation landscape in human cancer cells. Nucleic Acids Research 41:7286-7301. doi: 10.1093/nar/gkt504.
-
(2013)
Nucleic Acids Research
, vol.41
, pp. 7286-7301
-
-
Menendez, D.1
Nguyen, T.-A.2
Freudenberg, J.M.3
Mathew, V.J.4
Anderson, C.W.5
Jothi, R.6
Resnick, M.A.7
-
26
-
-
55049085391
-
Piperonyl butoxide activates c-Jun and ATF-2 in the hepatocytes of mice
-
doi: 10.1007/s00204-008-0283-0
-
Muguruma M, Arai K, Moto M, Nishimura J, Dewa Y, Mitsumori K. 2008. Piperonyl butoxide activates c-Jun and ATF-2 in the hepatocytes of mice. Archives of Toxicology 82:749-753. doi: 10.1007/s00204-008-0283-0.
-
(2008)
Archives of Toxicology
, vol.82
, pp. 749-753
-
-
Muguruma, M.1
Arai, K.2
Moto, M.3
Nishimura, J.4
Dewa, Y.5
Mitsumori, K.6
-
27
-
-
80051823334
-
Absence of polo-like kinase 3 in mice stabilizes Cdc25A after DNA damage but is not sufficient to produce tumors
-
doi: 10.1016/j.mrfmmm.2011.02.006
-
Myer DL, Robbins SB, Yin M, Boivin GP, Liu Y, Greis KD, Bahassiel M, Stambrook PJ. 2011. Absence of polo-like kinase 3 in mice stabilizes Cdc25A after DNA damage but is not sufficient to produce tumors. Mutation Research 714:1-10. doi: 10.1016/j.mrfmmm.2011.02.006.
-
(2011)
Mutation Research
, vol.714
, pp. 1-10
-
-
Myer, D.L.1
Robbins, S.B.2
Yin, M.3
Boivin, G.P.4
Liu, Y.5
Greis, K.D.6
Bahassiel, M.7
Stambrook, P.J.8
-
28
-
-
18444411948
-
Growth factors can activate ATF2 via a two-step mechanism: Phosphorylation of Thr71 through the Ras-MEK-ERK pathway and of Thr69 through RalGDS-Src-p38
-
doi: 10.1093/emboj/cdf361
-
Ouwens DM, de Ruiter ND, van der Zon GC, Carter AP, Schouten J, van der Burgt C, Kooistra K, Bos JL, Maassen JA, van Dam H. 2002. Growth factors can activate ATF2 via a two-step mechanism: phosphorylation of Thr71 through the Ras-MEK-ERK pathway and of Thr69 through RalGDS-Src-p38. The EMBO Journal 21:3782-3793. doi: 10.1093/emboj/cdf361.
-
(2002)
The EMBO Journal
, vol.21
, pp. 3782-3793
-
-
Ouwens, D.M.1
de Ruiter, N.D.2
van der Zon, G.C.3
Carter, A.P.4
Schouten, J.5
van der Burgt, C.6
Kooistra, K.7
Bos, J.L.8
Maassen, J.A.9
van Dam, H.10
-
29
-
-
33748069813
-
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes
-
doi: 10.1126/science.1128294
-
Ozcan U, Yilmaz E, Ozcan L, Furuhashi M, Vaillancourt E, Smith RO, Görgün CZ, Hotamisligil GS. 2006. Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes. Science 313:1137-1140. doi: 10.1126/science.1128294.
-
(2006)
Science
, vol.313
, pp. 1137-1140
-
-
Ozcan, U.1
Yilmaz, E.2
Ozcan, L.3
Furuhashi, M.4
Vaillancourt, E.5
Smith, R.O.6
Görgün, C.Z.7
Hotamisligil, G.S.8
-
30
-
-
84868139283
-
Discovery of a new class of liver receptor homolog-1 (LRH-1) antagonists: Virtual screening, synthesis and biological evaluation
-
doi: 10.1002/cmdc.201200307
-
Rey J, Hu H, Kyle F, Lai CF, Buluwela L, Coombes RC, Ortlund EA, Ali S, Snyder JP, Barrett AG. 2012. Discovery of a new class of liver receptor homolog-1 (LRH-1) antagonists: virtual screening, synthesis and biological evaluation. ChemMedChem 7:1909-1914. doi: 10.1002/cmdc.201200307.
-
(2012)
ChemMedChem
, vol.7
, pp. 1909-1914
-
-
Rey, J.1
Hu, H.2
Kyle, F.3
Lai, C.F.4
Buluwela, L.5
Coombes, R.C.6
Ortlund, E.A.7
Ali, S.8
Snyder, J.P.9
Barrett, A.G.10
-
31
-
-
57049111040
-
UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators
-
doi: 10.1016/j.devcel.2008.10.015
-
Rutkowski DT, Wu J, Back SH, Callaghan MU, Ferris SP, Iqbal J, Clark R, Miao H, Hassler JR, Fornek J, Katze MG, Hussain MM, Song B, Swathirajan J, Wang J, Yau GD, Kaufman RJ. 2008. UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators. Developmental Cell 15:829-840. doi: 10.1016/j.devcel.2008.10.015.
-
(2008)
Developmental Cell
, vol.15
, pp. 829-840
-
-
Rutkowski, D.T.1
Wu, J.2
Back, S.H.3
Callaghan, M.U.4
Ferris, S.P.5
Iqbal, J.6
Clark, R.7
Miao, H.8
Hassler, J.R.9
Fornek, J.10
Katze, M.G.11
Hussain, M.M.12
Song, B.13
Swathirajan, J.14
Wang, J.15
Yau, G.D.16
Kaufman, R.J.17
-
32
-
-
0034643336
-
Rapid degradation of a large fraction of newly synthesized proteins by proteasomes
-
doi: 10.1038/35008096
-
Schubert U, Antón LC, Gibbs J, Norbury CC, Yewdell JW, Bennink JR. 2000. Rapid degradation of a large fraction of newly synthesized proteins by proteasomes. Nature 404:770-774. doi: 10.1038/35008096.
-
(2000)
Nature
, vol.404
, pp. 770-774
-
-
Schubert, U.1
Antón, L.C.2
Gibbs, J.3
Norbury, C.C.4
Yewdell, J.W.5
Bennink, J.R.6
-
33
-
-
0038296940
-
Regulation of gene transcription by a constitutively active mutant of activating transcription factor 2 (ATF2)
-
Steinmuller L, Thiel G. 2003. Regulation of gene transcription by a constitutively active mutant of activating transcription factor 2 (ATF2). Biological Chemistry 384:667-672.
-
(2003)
Biological Chemistry
, vol.384
, pp. 667-672
-
-
Steinmuller, L.1
Thiel, G.2
-
34
-
-
27344435774
-
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
-
doi: 10.1073/pnas.0506580102
-
Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, Gillette MA, Paulovich A, Pomeroy SL, Golub TR, Lander ES, Mesirov JP. 2005. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proceedings of the National Academy of Sciences of the United States of America 102:15545-15550. doi: 10.1073/pnas.0506580102.
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, pp. 15545-15550
-
-
Subramanian, A.1
Tamayo, P.2
Mootha, V.K.3
Mukherjee, S.4
Ebert, B.L.5
Gillette, M.A.6
Paulovich, A.7
Pomeroy, S.L.8
Golub, T.R.9
Lander, E.S.10
Mesirov, J.P.11
-
35
-
-
81755184374
-
The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress
-
doi: 10.1091/mbc.E11-06-0510
-
Teske BF, Wek SA, Bunpo P, Cundiff JK, McClintick JN, Anthony TG, Wek RC. 2011. The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress. Molecular Biology of the Cell 22:4390-4405. doi: 10.1091/mbc.E11-06-0510.
-
(2011)
Molecular Biology of the Cell
, vol.22
, pp. 4390-4405
-
-
Teske, B.F.1
Wek, S.A.2
Bunpo, P.3
Cundiff, J.K.4
McClintick, J.N.5
Anthony, T.G.6
Wek, R.C.7
-
36
-
-
79951696692
-
A p53-independent role for the MDM2 antagonist Nutlin-3 in DNA damage response initiation
-
doi: 10.1186/1471-2407-11-79
-
Valentine JM, Kumar S, Moumen A. 2011. A p53-independent role for the MDM2 antagonist Nutlin-3 in DNA damage response initiation. BMC Cancer 11:79. doi: 10.1186/1471-2407-11-79.
-
(2011)
BMC Cancer
, vol.11
, pp. 79
-
-
Valentine, J.M.1
Kumar, S.2
Moumen, A.3
-
37
-
-
0029030855
-
ATF 2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response togenotoxic agents
-
van Dam H, Wilhelm D, Herr I, Steffen A, Herrlich P, Angel P. 1995. ATF 2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response togenotoxic agents. The EMBO Journal 14:1798-1811.
-
(1995)
The EMBO Journal
, vol.14
, pp. 1798-1811
-
-
van Dam, H.1
Wilhelm, D.2
Herr, I.3
Steffen, A.4
Herrlich, P.5
Angel, P.6
-
38
-
-
79960965302
-
Hyperosmotic stress-induced corneal epithelial cell death through activation of Polo-like kinase 3 and c-Jun
-
doi: 10.1167/iovs.10-6485
-
Wang L, Dai W, Lu L. 2011a. Hyperosmotic stress-induced corneal epithelial cell death through activation of Polo-like kinase 3 and c-Jun. Investigative Ophthalmology & Visual Science 52:3200-3206. doi: 10.1167/iovs.10-6485.
-
(2011)
Investigative Ophthalmology & Visual Science
, vol.52
, pp. 3200-3206
-
-
Wang, L.1
Dai, W.2
Lu, L.3
-
39
-
-
78751504781
-
Hyperosmotic stress-induced ATF-2 activation through Polo-like kinase 3 in human corneal epithelial cells
-
doi: 10.1074/jbc.M110.166009
-
Wang L, Payton R, Dai W, Lu L. 2011b. Hyperosmotic stress-induced ATF-2 activation through Polo-like kinase 3 in human corneal epithelial cells. The Journal of Biological Chemistry 286:1951-1958. doi: 10.1074/jbc.M110.166009.
-
(2011)
The Journal of Biological Chemistry
, vol.286
, pp. 1951-1958
-
-
Wang, L.1
Payton, R.2
Dai, W.3
Lu, L.4
-
40
-
-
79953786258
-
Small molecule agonists of the orphan nuclear receptors steroidogenic factor-1 (SF-1, NR5A1) and liver receptor homologue-1 (LRH-1, NR5A2)
-
doi: 10.1021/jm1014296
-
Whitby RJ, Stec J, Blind RD, Dixon S, Leesnitzer LM, Orband-Miller LA, Williams SP, Willson TM, Xu R, Zuercher WJ, Cai F, Ingraham HA. 2011. Small molecule agonists of the orphan nuclear receptors steroidogenic factor-1 (SF-1, NR5A1) and liver receptor homologue-1 (LRH-1, NR5A2). Journal of Medicinal Chemistry 54:2266-2281. doi: 10.1021/jm1014296.
-
(2011)
Journal of Medicinal Chemistry
, vol.54
, pp. 2266-2281
-
-
Whitby, R.J.1
Stec, J.2
Blind, R.D.3
Dixon, S.4
Leesnitzer, L.M.5
Orband-Miller, L.A.6
Williams, S.P.7
Willson, T.M.8
Xu, R.9
Zuercher, W.J.10
Cai, F.11
Ingraham, H.A.12
-
41
-
-
77954823661
-
Generation of ES cells for conditional expression of nuclear receptors and coregulators in vivo
-
doi: 10.1210/me.2010-0068
-
Wu S-P, Lee D-K, DeMayo FJ, Tsai SY, Tsai M-J. 2010. Generation of ES cells for conditional expression of nuclear receptors and coregulators in vivo. Molecular Endocrinology 24:1297-1304. doi: 10.1210/me.2010-0068.
-
(2010)
Molecular Endocrinology
, vol.24
, pp. 1297-1304
-
-
Wu, S.-P.1
Lee, D.-K.2
Demayo, F.J.3
Tsai, S.Y.4
Tsai, M.-J.5
-
42
-
-
0035900745
-
Plk3 functionally links DNA damage to cell cycle arrest and apoptosis at least in part via the p53 pathway
-
doi: 10.1074/jbc.M106050200
-
Xie S, Wu H, Wang Q, Cogswell JP, Usain I, Conn C, Stambrook P, Jhanwar-Uniyal M, Dia W. 2001. Plk3 functionally links DNA damage to cell cycle arrest and apoptosis at least in part via the p53 pathway. The Journal of Biological Chemistry 276:43305-43312. doi: 10.1074/jbc.M106050200.
-
(2001)
The Journal of Biological Chemistry
, vol.276
, pp. 43305-43312
-
-
Xie, S.1
Wu, H.2
Wang, Q.3
Cogswell, J.P.4
Usain, I.5
Conn, C.6
Stambrook, P.7
Jhanwar-Uniyal, M.8
Dia, W.9
-
43
-
-
0038278822
-
Bleeding due to disruption of a cargo-specific ER-to-Golgi transport complex
-
doi: 10.1038/ng1153
-
Zhang B, Cunningham MA, Nichols WC, Bernat JA, Seligsohn U, Pipe SW, McVey JH, Schulte-Overberg U, de Bosch NB, Ruiz-Saez A, White GC, Tuddenham EG, Kaufman RJ, Ginsburg D. 2003. Bleeding due to disruption of a cargo-specific ER-to-Golgi transport complex. Nature Genetics 34:220-225. doi: 10.1038/ng1153.
-
(2003)
Nature Genetics
, vol.34
, pp. 220-225
-
-
Zhang, B.1
Cunningham, M.A.2
Nichols, W.C.3
Bernat, J.A.4
Seligsohn, U.5
Pipe, S.W.6
McVey, J.H.7
Schulte-Overberg, U.8
de Bosch, N.B.9
Ruiz-Saez, A.10
White, G.C.11
Tuddenham, E.G.12
Kaufman, R.J.13
Ginsburg, D.14
-
44
-
-
79953794116
-
The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis
-
doi: 10.1038/emboj.2011.52
-
Zhang K, Wang S, Malhotra J, Hassler JR, Back SH, Wang G, Chang L, Xu W, Miao H, Leonardi R, Chen YE, Jackowski S, Kaufman RJ. 2011. The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis. The EMBO Journal 30:1357-1375. doi: 10.1038/emboj.2011.52.
-
(2011)
The EMBO Journal
, vol.30
, pp. 1357-1375
-
-
Zhang, K.1
Wang, S.2
Malhotra, J.3
Hassler, J.R.4
Back, S.H.5
Wang, G.6
Chang, L.7
Xu, W.8
Miao, H.9
Leonardi, R.10
Chen, Y.E.11
Jackowski, S.12
Kaufman, R.J.13
|