Genome-wide analysis of hepatic LRH-1 reveals a promoter binding preference and suggests a role in regulating genes of lipid metabolism in concert with FXR

BMC Genomics

Volumn 13, Issue 1, 2012, Pages

  Chong, Hansook K ^a,b,e   Biesinger, Jacob ^b,c   Seo, Young Kyo ^a   Xie, Xiaohui ^b,c   Osborne, Timothy F ^a,d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Irvine   (United States)

^d BURNHAM INSTITUTE   (United States)

^e AMBRY GENETICS   (United States)

Author keywords

CHIP seq; FXR; Lipid metabolism; LRH 1

Indexed keywords

CELL NUCLEUS RECEPTOR; FARNESOID X RECEPTOR; LIVER RECEPTOR HOMOLOG 1; NUCLEAR RECEPTOR NR4A; RETINOID RELATED ORPHAN RECEPTOR; UNCLASSIFIED DRUG; CELL RECEPTOR; FARNESOID X-ACTIVATED RECEPTOR; NR5A2 PROTEIN, MOUSE;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING SITE; CHROMATIN; CHROMATIN IMMUNOPRECIPITATION; DNA SEQUENCE; GENE FUNCTION; GENE ONTOLOGY ANALYSIS; GENE STRUCTURE; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC REGULATION; GENOME; GLUCOSE METABOLISM; LIPID METABOLISM; MALE; MOUSE; NONHUMAN; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; ANIMAL; C57BL MOUSE; GENE EXPRESSION REGULATION; GENETICS; LIVER; METABOLISM;

ANIMALS; BINDING SITES; CHROMATIN IMMUNOPRECIPITATION; GENE EXPRESSION REGULATION; GENOME; GENOME-WIDE ASSOCIATION STUDY; LIPID METABOLISM; LIVER; MALE; MICE; MICE, INBRED C57BL; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SEQUENCE ANALYSIS, DNA;

EID: 84857919534     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/1471-2164-13-51     Document Type: Article

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