Growth factors can activate ATF2 via a two-step mechanism: Phosphorylation of Thr71 through the Ras-MEK-ERK pathway and of Thr69 through RaIGDS-Src-p38

EMBO Journal

Volumn 21, Issue 14, 2002, Pages 3782-3793

  Ouwens, D Margriet ^a   De Ruiter, Nancy D ^a   Van der Zon, Gerard C M ^a   Carter, Andrew P ^a   Schouten, Jan ^a   Van der Burgt, Corina ^a   Kooistra, Klaas ^a   Bos, Johannes L ^a   Maassen, J Antonie ^a   Van Dam, Hans ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

ATF2; ERK; Mitogens; p38; Ras

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 2; EPIDERMAL GROWTH FACTOR; GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; RAS PROTEIN; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; THREONINE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ARTICLE; CELL PROLIFERATION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ACTIVATING TRANSCRIPTION FACTOR 2; BLOOD; CELL LINE; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; EPIDERMAL GROWTH FACTOR; HUMANS; INSULIN; MAP KINASE SIGNALING SYSTEM; PHOSPHORYLATION; THREONINE; TRANSCRIPTION FACTORS;

EID: 18444411948     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdf361     Document Type: Article

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