-
1
-
-
84861986053
-
Wnt/beta-catenin signaling and disease
-
Clevers H, Nusse R (2012) Wnt/beta-catenin signaling and disease. Cell 149: 1192-1205.
-
(2012)
Cell
, vol.149
, pp. 1192-1205
-
-
Clevers, H.1
Nusse, R.2
-
2
-
-
0029781509
-
Functional interaction of beta-catenin with the transcription factor LEF- 1
-
DOI 10.1038/382638a0
-
Behrens J, von Kries JP, Kuhl M, Bruhn L, Wedlich D, et al. (1996) Functional interaction of beta-catenin with the transcription factor LEF-1. Nature 382: 638-642. (Pubitemid 26268958)
-
(1996)
Nature
, vol.382
, Issue.6592
, pp. 638-642
-
-
Behrens, J.1
Von Kries, J.P.2
Kuhl, M.3
Bruhn, L.4
Wedlich, D.5
Grosschedl, R.6
Birchmeier, W.7
-
3
-
-
0001003110
-
XTcf-3 transcription factor mediates beta-catenin-induced axis formation in xenopus embryos
-
DOI 10.1016/S0092-8674(00)80112-9
-
Molenaar M, van de Wetering M, Oosterwegel M, Peterson-Maduro J, Godsave S, et al. (1996) XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos. Cell 86: 391-399. (Pubitemid 26272079)
-
(1996)
Cell
, vol.86
, Issue.3
, pp. 391-399
-
-
Molenaar, M.1
Van De, W.M.2
Oosterwegel, M.3
Peterson-Maduro, J.4
Godsave, S.5
Korinek, V.6
Roose, J.7
Destree, O.8
Clevers, H.9
-
4
-
-
0032473355
-
Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin
-
DOI 10.1093/emboj/17.5.1371
-
Ikeda S, Kishida S, Yamamoto H, Murai H, Koyama S, et al. (1998) Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin. EMBO J 17: 1371-1384. (Pubitemid 28105516)
-
(1998)
EMBO Journal
, vol.17
, Issue.5
, pp. 1371-1384
-
-
Ikeda, S.1
Kishida, S.2
Yamamoto, H.3
Murai, H.4
Koyama, S.5
Kikuchi, A.6
-
5
-
-
67650230896
-
Wnt/beta-catenin signaling: Components, mechanisms, and diseases
-
MacDonald BT, Tamai K, He X (2009) Wnt/beta-catenin signaling: components, mechanisms, and diseases. Dev Cell 17: 9-26.
-
(2009)
Dev Cell
, vol.17
, pp. 9-26
-
-
MacDonald, B.T.1
Tamai, K.2
He, X.3
-
6
-
-
4344562126
-
Mechanism of phosphorylation-dependent binding of APC to beta-catenin and its role in beta-catenin degradation
-
DOI 10.1016/j.molcel.2004.08.010, PII S109727650400471X
-
Ha NC, Tonozuka T, Stamos JL, Choi HJ, Weis WI (2004) Mechanism of phosphorylation-dependent binding of APC to beta-catenin and its role in beta-catenin degradation. Mol Cell 15: 511-521. (Pubitemid 39141779)
-
(2004)
Molecular Cell
, vol.15
, Issue.4
, pp. 511-521
-
-
Ha, N.-C.1
Tonozuka, T.2
Stamos, J.L.3
Choi, H.-J.4
Weis, W.I.5
-
7
-
-
4344684495
-
Crystal structure of a beta-catenin/APC complex reveals a critical role for APC phosphorylation in APC function
-
DOI 10.1016/j.molcel.2004.08.001, PII S1097276504004460
-
Xing Y, Clements WK, Le Trong I, Hinds TR, Stenkamp R, et al. (2004) Crystal structure of a beta-catenin/APC complex reveals a critical role for APC phosphorylation in APC function. Mol Cell 15: 523-533. (Pubitemid 39141780)
-
(2004)
Molecular Cell
, vol.15
, Issue.4
, pp. 523-533
-
-
Xing, Y.1
Clements, W.K.2
Le, T.I.3
Hinds, T.R.4
Stenkamp, R.5
Kimelman, D.6
Xu, W.7
-
8
-
-
79957597124
-
Deconstructing the beta-catenin destruction complex: Mechanistic roles for the tumor suppressor APC in regulating Wnt signaling
-
Roberts DM, Pronobis MI, Poulton JS, Waldmann JD, Stephenson EM, et al. (2011) Deconstructing the beta-catenin destruction complex: mechanistic roles for the tumor suppressor APC in regulating Wnt signaling. Mol Biol Cell 22: 1845-1863.
-
(2011)
Mol Biol Cell
, vol.22
, pp. 1845-1863
-
-
Roberts, D.M.1
Pronobis, M.I.2
Poulton, J.S.3
Waldmann, J.D.4
Stephenson, E.M.5
-
9
-
-
84861972831
-
Wnt signaling through inhibition of β-catenin degradation in an intact Axin1 complex
-
Li VS, Ng SS, Boersema PJ, Low TY, Karthaus WR, et al. (2012) Wnt signaling through inhibition of β-catenin degradation in an intact Axin1 complex. Cell 149: 1245-1256.
-
(2012)
Cell
, vol.149
, pp. 1245-1256
-
-
Li, V.S.1
Ng, S.S.2
Boersema, P.J.3
Low, T.Y.4
Karthaus, W.R.5
-
10
-
-
38549180413
-
Abundance, complexation, and trafficking of Wnt/beta-catenin signaling elements in response to Wnt3a
-
Yokoyama N, Yin D, Malbo CC (2007) Abundance, complexation, and trafficking of Wnt/beta-catenin signaling elements in response to Wnt3a. J Mol Signal: 2, e11.
-
(2007)
J Mol Signal
, vol.2
-
-
Yokoyama, N.1
Yin, D.2
Malbo, C.C.3
-
11
-
-
84856635802
-
Triple SILAC to determine stimulus specific interactions in the Wnt pathway
-
Hilger M, Mann M (2012) Triple SILAC to determine stimulus specific interactions in the Wnt pathway. J Proteome Res 11: 982-994.
-
(2012)
J Proteome Res
, vol.11
, pp. 982-994
-
-
Hilger, M.1
Mann, M.2
-
12
-
-
0025938038
-
Identification and characterization of the familial adenomatous polyposis coli gene
-
Groden J, Thliveris A, Samowitz W, Carlson M, Gelbert L, et al. (1991) Identification and characterization of the familial adenomatous polyposis coli gene. Cell 66: 589-600.
-
(1991)
Cell
, vol.66
, pp. 589-600
-
-
Groden, J.1
Thliveris, A.2
Samowitz, W.3
Carlson, M.4
Gelbert, L.5
-
13
-
-
33847397617
-
The canonical Wnt signalling pathway and its APC partner in colon cancer development
-
DOI 10.1136/gut.2006.093310
-
Schneikert J, Behrens J (2007) The canonical Wnt signalling pathway and its APC partner in colon cancer development. Gut 56: 417-425. (Pubitemid 46579774)
-
(2007)
Gut
, vol.56
, Issue.3
, pp. 417-425
-
-
Schneikert, J.1
Behrens, J.2
-
14
-
-
0034604366
-
Crystal structure of the amino-terminal coiled-coil domain of the APC tumor suppressor
-
Day CL, Alber T (2000) Crystal structure of the amino-terminal coiled-coil domain of the APC tumor suppressor. J Mol Biol 301: 147-156.
-
(2000)
J Mol Biol
, vol.301
, pp. 147-156
-
-
Day, C.L.1
Alber, T.2
-
15
-
-
46749094255
-
Novel self-association of the APC molecule affects APC clusters and cell migration
-
DOI 10.1242/jcs.029470
-
Li Z, Kroboth K, Newton IP, Näthke IS (2008) Novel self-association of the APC molecule affects APC clusters and cell migration. J Cell Sci 121: 1916-1925. (Pubitemid 351943385)
-
(2008)
Journal of Cell Science
, vol.121
, Issue.11
, pp. 1916-1925
-
-
Li, Z.1
Kroboth, K.2
Newton, I.P.3
Nathke, I.S.4
-
16
-
-
0027756014
-
Association of the APC tumor suppressor protein with catenins
-
Su LK, Vogelstein B, Kinzler KW (1993) Association of the APC tumor suppressor protein with catenins. Science 262: 1734-1737. (Pubitemid 24030097)
-
(1993)
Science
, vol.262
, Issue.5140
, pp. 1734-1737
-
-
Su, L.-K.1
Vogelstein, B.2
Kinzler, K.W.3
-
17
-
-
0035890060
-
Molecular mechanisms of beta-catenin recognition by adenomatous polyposis coli revealed by the structure of an APC-beta-catenin complex
-
DOI 10.1093/emboj/20.22.6203
-
Eklof Spink K, Fridman SG, Weis WI (2001). Molecular mechanisms of beta-catenin recognition by adenomatous polyposis coli revealed by the structure of an APC-beta-catenin complex. EMBO J 20: 6203-6212. (Pubitemid 33078694)
-
(2001)
EMBO Journal
, vol.20
, Issue.22
, pp. 6203-6212
-
-
Spink, K.E.1
Fridman, S.G.2
Weis, W.I.3
-
18
-
-
33745276261
-
The Third 20 Amino Acid Repeat Is the Tightest Binding Site of APC for beta-Catenin
-
DOI 10.1016/j.jmb.2006.04.064, PII S0022283606005572
-
Liu J, Xing Y, Hinds TR, Zheng J, Xu W (2006) The third 20 amino acid repeat is the tightest binding site of APC for beta-catenin. J Mol Biol 360: 133-144. (Pubitemid 43927813)
-
(2006)
Journal of Molecular Biology
, vol.360
, Issue.1
, pp. 133-144
-
-
Liu, J.1
Xing, Y.2
Hinds, T.R.3
Zheng, J.4
Xu, W.5
-
19
-
-
0027738023
-
Association of the APC gene product with beta-catenin
-
Rubinfeld B, Souza B, Albert I, Muller O, Chamberlain SH, et al. (1993) Association of the APC gene product with beta-catenin. Science 262: 1731-1734. (Pubitemid 24030096)
-
(1993)
Science
, vol.262
, Issue.5140
, pp. 1731-1734
-
-
Rubinfeld, B.1
Souza, B.2
Albert, I.3
Muller, O.4
Chamberlain, S.H.5
Masiarz, F.R.6
Munemitsu, S.7
Polakis, P.8
-
20
-
-
58049196841
-
Beta-catenin degradation mediated by the CID domain of APC provides a model for the selection of APC mutations in colorectal, desmoid and duodenal tumours
-
Kohler EM, Chandra SH, Behrens J, Schneikert J (2009) Beta-catenin degradation mediated by the CID domain of APC provides a model for the selection of APC mutations in colorectal, desmoid and duodenal tumours. Hum Mol Genet 18: 213-226.
-
(2009)
Hum Mol Genet
, vol.18
, pp. 213-226
-
-
Kohler, E.M.1
Chandra, S.H.2
Behrens, J.3
Schneikert, J.4
-
21
-
-
0032562603
-
Functional interaction of an Axin homolog, conductin, with beta-catenin, APC, and GSK3beta
-
Behrens J, Jerchow BA, Wurtele M, Grimm J, Asbrand C, et al. (1998) Functional interaction of an Axin homolog, conductin, with beta-catenin, APC, and GSK3beta. Science 280: 596-599.
-
(1998)
Science
, vol.280
, pp. 596-599
-
-
Behrens, J.1
Jerchow, B.A.2
Wurtele, M.3
Grimm, J.4
Asbrand, C.5
-
22
-
-
0034657187
-
Structural basis of the Axin-adenomatous polyposis coli interaction
-
Spink KE, Polakis P, Weis WI (2000) Structural basis of the Axin-adenomatous polyposis coli interaction. EMBO J 19: 2270-2279. (Pubitemid 30259008)
-
(2000)
EMBO Journal
, vol.19
, Issue.10
, pp. 2270-2279
-
-
Spink, K.E.1
Polakis, P.2
Weis, W.I.3
-
23
-
-
41549117418
-
Cell regulation by the Apc protein Apc as master regulator of epithelia
-
McCartney B, Näthke IS (2008) Cell regulation by the Apc protein Apc as master regulator of epithelia. Curr Opin Cell Biol 20: 186-193.
-
(2008)
Curr Opin Cell Biol
, vol.20
, pp. 186-193
-
-
McCartney, B.1
Näthke, I.S.2
-
24
-
-
77949659176
-
Contribution of the 15 amino acid repeats of truncated APC to beta-catenin degradation and selection of APC mutations in colorectal tumours from FAP patients
-
Kohler EM, Brauburger K, Behrens J, Schneikert J (2010) Contribution of the 15 amino acid repeats of truncated APC to beta-catenin degradation and selection of APC mutations in colorectal tumours from FAP patients. Oncogene 29: 1663-1671.
-
(2010)
Oncogene
, vol.29
, pp. 1663-1671
-
-
Kohler, E.M.1
Brauburger, K.2
Behrens, J.3
Schneikert, J.4
-
25
-
-
0030871048
-
Loss of beta-catenin regulation by the APC tumor suppressor protein correlates with loss of structure due to common somatic mutations of the gene
-
Rubinfeld B, Albert I, Porfiri E, Munemitsu S, Polakis P (1997) Loss of beta-catenin regulation by the APC tumor suppressor protein correlates with loss of structure due to common somatic mutations of the gene. Cancer Res 57: 4624-4630. (Pubitemid 27441070)
-
(1997)
Cancer Research
, vol.57
, Issue.20
, pp. 4624-4630
-
-
Rubinfeld, B.1
Albert, I.2
Porfiri, E.3
Munemitsu, S.4
Polakis, P.5
-
26
-
-
84863922124
-
Comprehensive molecular characterization of human colon and rectal cancer
-
Muzny DM, Bainbridge MN, Chang K, Dinh HH, Drummond JA, et al. (2012) Comprehensive molecular characterization of human colon and rectal cancer. Nature 487: 330-337.
-
(2012)
Nature
, vol.487
, pp. 330-337
-
-
Muzny, D.M.1
Bainbridge, M.N.2
Chang, K.3
Dinh, H.H.4
Drummond, J.A.5
-
27
-
-
0026894053
-
Somatic mutations of the APC gene in colorectal tumors: Mutation cluster region in the APC gene
-
Miyoshi Y, Nagase H, Ando H, Horii A, Ichii S, et al. (1992) Somatic mutations of the APC gene in colorectal tumors: mutation cluster region in the APC gene. Hum Mol Genet 1: 229-233.
-
(1992)
Hum Mol Genet
, vol.1
, pp. 229-233
-
-
Miyoshi, Y.1
Nagase, H.2
Ando, H.3
Horii, A.4
Ichii, S.5
-
28
-
-
0034724186
-
APC mutations in sporadic colorectal tumors: A mutational 'hotspot' and interdependence of the 'two hits'
-
DOI 10.1073/pnas.97.7.3352
-
Rowan AJ, Lamlum H, Ilyas M, Wheeler J, Straub J, et al. (2000) APC mutations in sporadic colorectal tumors: A mutational "hotspot" and interdependence of the "two hits". Proc Natl Acad Sci USA 97: 3352-3357. (Pubitemid 30183306)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.7
, pp. 3352-3357
-
-
Rowan, A.J.1
Lamlum, H.2
Ilyas, M.3
Wheeler, J.4
Straub, J.5
Papadopoulou, A.6
Bicknell, D.7
Bodmer, W.F.8
Tomlinson, I.P.M.9
-
29
-
-
0037416148
-
Nuclear export of the APC tumour suppressor controls beta-catenin function in transcription
-
DOI 10.1093/emboj/cdg105
-
Rosin-Arbesfeld R, Cliffe A, Brabletz T, Bienz M (2003) Nuclear export of the APC tumour suppressor controls beta-catenin function in transcription. EMBO J 22: 1101-1113. (Pubitemid 36313594)
-
(2003)
EMBO Journal
, vol.22
, Issue.5
, pp. 1101-1113
-
-
Rosin-Arbesfeld, R.1
Cliffe, A.2
Brabletz, T.3
Bienz, M.4
-
30
-
-
45749140081
-
Functional definition of the mutation cluster region of adenomatous polyposis coli in colorectal tumours
-
DOI 10.1093/hmg/ddn095
-
Kohler EM, Derungs A, Daum G, Behrens J, Schneikert J (2008) Functional definition of the mutation cluster region of adenomatous polyposis coli in colorectal tumours. Hum Mol Genet 17: 1978-1987. (Pubitemid 351865846)
-
(2008)
Human Molecular Genetics
, vol.17
, Issue.13
, pp. 1978-1987
-
-
Kohler, E.M.1
Derungs, A.2
Daum, G.3
Behrens, J.4
Schneikert, J.5
-
31
-
-
80052258209
-
APC mutations in colorectal tumours from FAP patients are selected for CtBP-mediated oligomerisation of truncated APC
-
Schneikert J, Brauburger K, Behrens J (2011) APC mutations in colorectal tumours from FAP patients are selected for CtBP-mediated oligomerisation of truncated APC. Hum Mol Genet 20: 3554-3564.
-
(2011)
Hum Mol Genet
, vol.20
, pp. 3554-3564
-
-
Schneikert, J.1
Brauburger, K.2
Behrens, J.3
-
32
-
-
0034682888
-
Asef, a link between the tumor suppressor APC and G-protein signaling
-
DOI 10.1126/science.289.5482.1194
-
Kawasaki Y, Senda T, Ishidate T, Koyama R, Morishita T, et al. (2000) Asef, a link between the tumor suppressor APC and G-protein signaling. Science 289: 1194-1197. (Pubitemid 30650732)
-
(2000)
Science
, vol.289
, Issue.5482
, pp. 1194-1197
-
-
Kawasaki, Y.1
Senda, T.2
Ishidate, T.3
Koyama, R.4
Morishita, T.5
Iwayama, Y.6
Higuchi, O.7
Akiyama, T.8
-
33
-
-
0036226855
-
Identification of a link between the tumour suppressor APC and the kinesin superfamily
-
DOI 10.1038/ncb779
-
Jimbo T, Kawasaki Y, Koyama R, Sato R, Takada S, et al. (2002) Identification of a link between the tumour suppressor APC and the kinesin superfamily. Nat Cell Biol 4: 323-327. (Pubitemid 34308860)
-
(2002)
Nature Cell Biology
, vol.4
, Issue.4
, pp. 323-327
-
-
Jimbo, T.1
Kawasaki, Y.2
Koyama, R.3
Sato, R.4
Takada, S.5
Haraguchi, K.6
Akiyama, T.7
-
34
-
-
10644281068
-
Interaction with IQGAP1 links APC to Rac1, Cdc42, and actin filaments during cell polarization and migration
-
DOI 10.1016/j.devcel.2004.10.017, PII S153458070400382X
-
Watanabe T, Wang S, Noritake J, Sato K, Fukata M, et al. (2004) Interaction with IQGAP1 links APC to Rac1, Cdc42, and actin filaments during cell polarization and migration. Dev Cell 7: 871-883. (Pubitemid 39654731)
-
(2004)
Developmental Cell
, vol.7
, Issue.6
, pp. 871-883
-
-
Watanabe, T.1
Wang, S.2
Noritake, J.3
Sato, K.4
Fukata, M.5
Takefuji, M.6
Nakagawa, M.7
Izumi, N.8
Akiyama, T.9
Kaibuchi, K.10
-
35
-
-
34249061491
-
Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling
-
DOI 10.1126/science/1141515
-
Major MB, Camp ND, Berndt JD, Yi X, Goldenberg SJ, et al. (2007) Wilms tumor suppressor WTX negatively regulates Wnt/beta-catenin signaling. Science 316: 1043-1046. (Pubitemid 46799493)
-
(2007)
Science
, vol.316
, Issue.5827
, pp. 1043-1046
-
-
Major, M.B.1
Camp, N.D.2
Berndt, J.D.3
Yi, X.4
Goldenberg, S.J.5
Hubbert, C.6
Biechele, T.L.7
Gingras, A.-C.8
Zheng, N.9
MacCoss, M.J.10
Angers, S.11
Moon, R.T.12
-
36
-
-
36549030350
-
AMER1 regulates the distribution of the tumor suppressor APC between microtubules and the plasma membrane
-
DOI 10.1242/jcs.011320
-
Grohmann A, Tanneberger K, Alzner A, Schneikert J, Behrens J (2007) AMER1 regulates the distribution of the tumor suppressor APC between microtubules and the plasma membrane. J. Cell Sci 120: 3738-3747. (Pubitemid 350187356)
-
(2007)
Journal of Cell Science
, vol.120
, Issue.21
, pp. 3738-3747
-
-
Grohmann, A.1
Tanneberger, K.2
Alzner, A.3
Schneikert, J.4
Behrens, J.5
-
37
-
-
0032533845
-
Identification of a brain-specific APC homologue, APCL, and its interaction with beta-catenin
-
Nakagawa H, Murata Y, Koyama K, Fujiyama A, Miyoshi Y, et al. (1998) Identification of a brain-specific APC homologue, APCL, and its interaction with beta-catenin. Cancer Res 58: 5176-5181. (Pubitemid 28521179)
-
(1998)
Cancer Research
, vol.58
, Issue.22
, pp. 5176-5181
-
-
Nakagawa, H.1
Murata, Y.2
Koyama, K.3
Fujiyama, A.4
Miyoshi, Y.5
Monden, M.6
Akiyama, T.7
Nakamura, Y.8
-
38
-
-
0033611574
-
Identification of APC2, a homologue of the adenomatous polyposis coli tumour suppressor
-
DOI 10.1016/S0960-9822(99)80024-4
-
van Es JH, Kirkpatrick C, van de Wetering M, Molenaar M, Miles A, et al. (1999) Identification of APC2, a homologue of the adenomatous polyposis coli tumour suppressor. Curr Biol 9: 105-108. (Pubitemid 29085389)
-
(1999)
Current Biology
, vol.9
, Issue.2
, pp. 105-108
-
-
Van Es, J.H.1
Kirkpatrick, C.2
Van De, W.M.3
Molenaar, M.4
Miles, A.5
Kuipers, J.6
Destree, O.7
Peifer, M.8
Clevers, H.9
-
39
-
-
0035504713
-
Human APC2 localization and allelic imbalance
-
Jarrett CR, Blancato J, Cao T, Bressette DS, Cepeda M, et al. (2001) Human APC2 localisation and allelic imbalance. Cancer Res 61: 7978-7984. (Pubitemid 33050988)
-
(2001)
Cancer Research
, vol.61
, Issue.21
, pp. 7978-7984
-
-
Jarrett, C.R.1
Blancato, J.2
Cao, T.3
Bressette, D.S.4
Cepeda, M.5
Young, P.E.6
King, R.C.7
Byers, S.W.8
-
40
-
-
4243067196
-
The roles of APC and Axin derived from experimental and theoretical analysis of the Wnt pathway
-
Lee E, Salic A, Krüger R, Heinrich R, Kirschner MW (2003) The roles of APC and Axin derived from experimental and theoretical analysis of the Wnt pathway. PLoS Biol 1: e10.
-
(2003)
PLoS Biol
, vol.1
-
-
Lee, E.1
Salic, A.2
Krüger, R.3
Heinrich, R.4
Kirschner, M.W.5
-
41
-
-
0032492954
-
Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3beta
-
Hart MJ, de los Santos R, Albert IN, Rubinfeld B, Polakis P (1998) Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta. Curr Biol 8: 573-581. (Pubitemid 28222891)
-
(1998)
Current Biology
, vol.8
, Issue.10
, pp. 573-581
-
-
Hart, M.J.1
De Los, S.R.2
Albert, I.N.3
Rubinfeld, B.4
Polakis, P.5
-
42
-
-
0031813650
-
Axin, an inhibitor of the Wnt signalling pathway, interacts with β- catenin, GSK-3β and APC and reduces the β-catenin level
-
Nakamura T, Hamada F, Ishidate T, Anai K, Kawahara K, et al. (1998) Axin, an inhibitor of the Wnt signalling pathway interacts with β-catenin, GSK-3β and APC and reduces the β-catenin level. Genes Cells 3: 395-403. (Pubitemid 28387083)
-
(1998)
Genes to Cells
, vol.3
, Issue.6
, pp. 395-403
-
-
Nakamura, T.1
Hamada, F.2
Ishidate, T.3
Anai, K.-I.4
Kawahara, K.5
Toyoshima, K.6
Akiyama, T.7
-
43
-
-
53249090244
-
Recruitment of adenomatous polyposis coli and beta-catenin to Axin-puncta
-
Faux MC, Coates JL, Catimel B, Cody S, Clayton AH, et al. (2008) Recruitment of adenomatous polyposis coli and beta-catenin to Axin-puncta. Oncogene 27: 5808-5820.
-
(2008)
Oncogene
, vol.27
, pp. 5808-5820
-
-
Faux, M.C.1
Coates, J.L.2
Catimel, B.3
Cody, S.4
Clayton, A.H.5
-
44
-
-
34249890531
-
The DIX domain of Dishevelled confers Wnt signaling by dynamic polymerization
-
DOI 10.1038/nsmb1247, PII NSMB1247
-
Schwarz-Romond T, Fiedler M, Shibata N, Butler PJ, Kikuchi A, et al. (2007) The DIX domain of Dishevelled confers Wnt signaling by dynamic oligomerisation. Nat Struct Mol Biol 14: 484-492. (Pubitemid 46871810)
-
(2007)
Nature Structural and Molecular Biology
, vol.14
, Issue.6
, pp. 484-492
-
-
Schwarz-Romond, T.1
Fiedler, M.2
Shibata, N.3
Butler, P.J.G.4
Kikuchi, A.5
Higuchi, Y.6
Bienz, M.7
-
45
-
-
84861699364
-
The Adenomatous polyposis coli tumour suppressor is essential for Axin complex assembly and function and opposes Axin's interaction with Dishevelled
-
Mendoza-Topaz C, Mieszczanek J, Bienz M (2011) The Adenomatous polyposis coli tumour suppressor is essential for Axin complex assembly and function and opposes Axin's interaction with Dishevelled. Open Biol 1: e110013.
-
(2011)
Open Biol
, vol.1
-
-
Mendoza-Topaz, C.1
Mieszczanek, J.2
Bienz, M.3
-
46
-
-
79952148045
-
Dishevelled interacts with the DIX domain oligomerisation interface of Axin to interfere with its function in down-regulating β-catenin
-
Fiedler M, Mendoza-Topaz C, Rutherford TJ, Mieszczanek J, Bienz M (2011) Dishevelled interacts with the DIX domain oligomerisation interface of Axin to interfere with its function in down-regulating β-catenin. Proc Natl Acad Sci USA 108: 1937-1942.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 1937-1942
-
-
Fiedler, M.1
Mendoza-Topaz, C.2
Rutherford, T.J.3
Mieszczanek, J.4
Bienz, M.5
-
47
-
-
33745809820
-
Adenomatous polyposis coli (APC) differentially regulates beta-catenin phosphorylation and ubiquitination in colon cancer cells
-
DOI 10.1074/jbc.M600831200
-
Yang J, Zhang W, Evans PM, Chen X, He X et al. (2006) Adenomatous polyposis coli (APC) differentially regulates beta-catenin phosphorylation and ubiquitination in colon cancer cells. J Biol Chem 281: 17751-17757. (Pubitemid 44035574)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.26
, pp. 17751-17757
-
-
Yang, J.1
Zhang, W.2
Evans, P.M.3
Chen, X.4
He, X.5
Liu, C.6
-
48
-
-
84863012691
-
Adenomatous polyposis coli (APC) regulates multiple signaling pathways by enhancing glycogen synthase kinase-3 (GSK-3) activity
-
Valvezan AJ, Zhang F, Diehl JA, Klein PS (2012) Adenomatous polyposis coli (APC) regulates multiple signaling pathways by enhancing glycogen synthase kinase-3 (GSK-3) activity. J Biol Chem 287: 3823-3832.
-
(2012)
J Biol Chem
, vol.287
, pp. 3823-3832
-
-
Valvezan, A.J.1
Zhang, F.2
Diehl, J.A.3
Klein, P.S.4
-
49
-
-
84865228580
-
Reversible Modification of Adenomatous Polyposis Coli (APC) with K63-linked Polyubiquitin Regulates the Assembly and Activity of the β-Catenin Destruction Complex
-
Tran H, Polakis P (2012) Reversible Modification of Adenomatous Polyposis Coli (APC) with K63-linked Polyubiquitin Regulates the Assembly and Activity of the β-Catenin Destruction Complex. J Biol Chem 287: 28552-28563.
-
(2012)
J Biol Chem
, vol.287
, pp. 28552-28563
-
-
Tran, H.1
Polakis, P.2
-
50
-
-
0033577808
-
Domains of Axin involved in protein-protein interactions, Wnt pathway inhibition, and intracellular localization
-
DOI 10.1083/jcb.145.4.741
-
Fagotto F, Jho E, Zeng L, Kurth T, Joos T, et al. (1999) Domains of Axin involved in protein-protein interactions, Wnt pathway inhibition, and Intracellular localisation. J Cell Biol 145: 741-756. (Pubitemid 29240852)
-
(1999)
Journal of Cell Biology
, vol.145
, Issue.4
, pp. 741-756
-
-
Fagotto, F.1
Jho, E.-H.2
Zeng, L.3
Kurth, T.4
Joos, T.5
Kaufmann, C.6
Costantini, F.7
-
51
-
-
0033577732
-
Interaction of Axin and Dvl-2 proteins regulates Dvl-2-stimulated TCF-dependent transcription
-
DOI 10.1093/emboj/18.10.2823
-
Smalley MJ, Sara E, Paterson H, Naylor S, Cook D, et al. (1999) Interaction of Axin and Dvl-2 proteins regulates Dvl-2-stimulated TCF-dependent transcription. EMBO J 18: 2823-2835. (Pubitemid 29233954)
-
(1999)
EMBO Journal
, vol.18
, Issue.10
, pp. 2823-2835
-
-
Smalley, M.J.1
Sara, E.2
Paterson, H.3
Naylor, S.4
Cook, D.5
Jayatilake, H.6
Fryer, L.G.7
Hutchinson, L.8
Fry, M.J.9
Dale, T.C.10
-
52
-
-
3042585855
-
Downregulation of beta-catenin by p53 involves changes in the rate of beta-catenin phosphorylation and Axin dynamics
-
DOI 10.1038/sj.onc.1207587
-
Levina E, Oren M, Ben-Ze'evA (2004) Downregulation of betacatenin by p53 involves changes in the rate of beta-catenin phosphorylation and Axin dynamics. Oncogene 23: 4444-4453. (Pubitemid 38850423)
-
(2004)
Oncogene
, vol.23
, Issue.25
, pp. 4444-4453
-
-
Levina, E.1
Oren, M.2
Ben-Ze'ev, A.3
-
53
-
-
1242272084
-
Nucleo-cytoplasmic Shuttling of Axin, a Negative Regulator of the Wnt-beta-Catenin Pathway
-
DOI 10.1074/jbc.M307253200
-
Wiechens N, Heinle K, Englmeier L, Schohl A, Fagotto F (2004) Nucleo-cytoplasmic shuttling of Axin, a negative regulator of the Wnt-beta-catenin Pathway. J Biol Chem 279: 5263-5267. (Pubitemid 38220546)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.7
, pp. 5263-5267
-
-
Wiechens, N.1
Heinle, K.2
Englmeier, L.3
Schohl, A.4
Fagotto, F.5
-
54
-
-
0027930066
-
The APC gene product associates with microtubules in vivo and promotes their assembly in vitro
-
Munemitsu S, Souza B, Müller O, Albert I, Rubinfeld B, et al. (1994) The APC gene product associates with microtubules in vivo and promotes their assembly in vitro. Cancer Res 54: 3676-3681. (Pubitemid 24241177)
-
(1994)
Cancer Research
, vol.54
, Issue.14
, pp. 3676-3681
-
-
Munemitsu, S.1
Souza, B.2
Muller, O.3
Albert, I.4
Rubinfeld, B.5
Polakis, P.6
-
55
-
-
0037054547
-
The adenomatous polyposis coli protein unambiguously localizes to microtubule plus ends and is involved in establishing parallel arrays of microtubule bundles in highly polarized epithelial cells
-
DOI 10.1083/jcb.200203001
-
Mogensuen MM, Tucker JB, Mackie JB, Prescott AR, Näthke IS (2002) The adenomatous polyposis coli protein unambiguously localises to microtubule plus ends and is involved in establishing parallel arrays of microtubule bundles in highly polarized epithelial cells. J Cell Biol 157: 1041-1048. (Pubitemid 34839778)
-
(2002)
Journal of Cell Biology
, vol.157
, Issue.6
, pp. 1041-1048
-
-
Mogensen, M.M.1
Tucker, J.B.2
Mackie, J.B.3
Prescott, A.R.4
Nathke, I.S.5
-
56
-
-
0029595302
-
Characterization of a cis-Golgi matrix protein, GM130
-
DOI 10.1083/jcb.131.6.1715
-
Nakamura N, Rabouille C, Watson R, Nilsson T, Hui N, et al. (1995) Characterization of a cis-Golgi matrix protein, GM130. J Cell Biol. 131: 1715-26. (Pubitemid 26007969)
-
(1995)
Journal of Cell Biology
, vol.131
, Issue.6 II
, pp. 1715-1726
-
-
Nakamura, N.1
Rabouille, C.2
Watson, R.3
Nilsson, T.4
Hui, N.5
Slusarewicz, P.6
Kreis, T.E.7
Warren, G.8
-
57
-
-
0027244942
-
Giantin, a novel conserved Golgi membrane protein containing a cytoplasmic domain of at least 350 kDa
-
Linstedt AD, Hauri HP (1993) Giantin, a novel conserved Golgi membrane protein containing a cytoplasmic domain of at least 350 kDa. Mol Biol Cell 4: 679-93. (Pubitemid 23227154)
-
(1993)
Molecular Biology of the Cell
, vol.4
, Issue.7
, pp. 679-693
-
-
Linstedt, A.D.1
Hauri, H.-P.2
-
58
-
-
0030889062
-
Distinct compartmentalization of TGN46 and beta1,4-galactosyltransferase in HeLa cells
-
Prescott AR, Lucocq JM, James J, Lister JM, Ponnambalam S (1997) Distinct compartmentalization of TGN46 and beta 1,4-galactosyltransferase in HeLa cells. Eur J Cell Biol 72: 238-46. (Pubitemid 27117130)
-
(1997)
European Journal of Cell Biology
, vol.72
, Issue.3
, pp. 238-246
-
-
Prescott, A.R.1
Lucocq, J.M.2
James, J.3
Lister, J.M.4
Ponnambalam, S.5
-
59
-
-
84879723716
-
Functional comparison of human Adenomatous Polyposis Coli (APC) and APC-Like in targeting beta-catenin for degradation
-
in press
-
Schneikert J, Vijaya Chandra SH, Ruppert JG, Ray S, Wenzel EM et al. (2013) Functional comparison of human Adenomatous Polyposis Coli (APC) and APC-Like in targeting beta-catenin for degradation. PloS ONE, in press.
-
(2013)
PloS ONE
-
-
Schneikert, J.1
Vijaya Chandra, S.H.2
Ruppert, J.G.3
Ray, S.4
Wenzel, E.M.5
-
60
-
-
33646583259
-
Nucleo-cytoplasmic distribution of beta-catenin is regulated by retention
-
Krieghoff E, Behrens J, Mayr B (2006) Nucleo-cytoplasmic distribution of beta-catenin is regulated by retention. J Cell Sci 119: 1453-1463.
-
(2006)
J Cell Sci
, vol.119
, pp. 1453-1463
-
-
Krieghoff, E.1
Behrens, J.2
Mayr, B.3
-
61
-
-
33846626414
-
Truncated APC regulates the transcriptional activity of beta-catenin in a cell cycle dependent manner
-
DOI 10.1093/hmg/ddl464
-
Schneikert J, Grohmann A, Behrens J (2007) Truncated APC regulates the transcriptional activity of beta-catenin in a cell cycle dependent manner. Hum Mol Genet 16: 199-209. (Pubitemid 46179002)
-
(2007)
Human Molecular Genetics
, vol.16
, Issue.2
, pp. 199-209
-
-
Schneikert, J.1
Grohmann, A.2
Behrens, J.3
-
62
-
-
0034602160
-
Complex formation of adenomatous polyposis coli gene product and axin facilitates glycogen synthase kinase-3 beta-dependent phosphorylation of beta-catenin and down-regulates beta-catenin
-
Hinoi T, Yamamoto H, Kishida M, Takada S, Kishida S et al. (2000) Complex formation of adenomatous polyposis coli gene product and axin facilitates glycogen synthase kinase-3 beta-dependent phosphorylation of beta-catenin and down-regulates beta-catenin. J Biol Chem 275: 34399-34406.
-
(2000)
J Biol Chem
, vol.275
, pp. 34399-34406
-
-
Hinoi, T.1
Yamamoto, H.2
Kishida, M.3
Takada, S.4
Kishida, S.5
-
63
-
-
0033563226
-
Apc1638T: A mouse model delineating critical domains of the adenomatous polyposis coli protein involved in tumorigenesis and development
-
Smits R, Kielman MF, Breukel C, Zurcher C, Neufeld K, et al. (1999) Apc1638T: a mouse model delineating critical domains of the adenomatous polyposis coli protein involved in tumorigenesis and development. Genes Dev 13: 1309-1321. (Pubitemid 29250198)
-
(1999)
Genes and Development
, vol.13
, Issue.10
, pp. 1309-1321
-
-
Smits, R.1
Kielman, M.F.2
Breukel, C.3
Zurcher, C.4
Neufeld, K.5
Jagmohan-Changur, S.6
Hofland, N.7
Van Dijk, J.8
White, R.9
Edelmann, W.10
Kucherlapati, R.11
Meera, K.P.12
Fodde, R.13
-
64
-
-
68249083454
-
A targeted constitutive mutation in the APC tumor suppressor gene underlies mammary but not intestinal tumorigenesis
-
Gaspar C, Franken P, Molenaar L, Breukel C, van der Valk M, et al. (2009) A targeted constitutive mutation in the APC tumor suppressor gene underlies mammary but not intestinal tumorigenesis. PLoS Genet 5: e1000547.
-
(2009)
PLoS Genet
, vol.5
-
-
Gaspar, C.1
Franken, P.2
Molenaar, L.3
Breukel, C.4
Van Der Valk, M.5
-
65
-
-
84870690295
-
Kinetic responses of β-catenin specify the sites of Wnt control
-
Hernández AR, Klein AM, Kirschner MW (2012) Kinetic responses of β-catenin specify the sites of Wnt control. Science 338:1337-1340.
-
(2012)
Science
, vol.338
, pp. 1337-1340
-
-
Hernández, A.R.1
Klein, A.M.2
Kirschner, M.W.3
-
66
-
-
0036149985
-
Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors
-
DOI 10.1128/MCB.22.4.1184-1193.2002
-
Lustig B, Jerchow B, Sachs M, Weiler S, Pietsch T, et al. (2002) Negative feedback loop of Wnt signaling through upregulation of conductin/Axin2 in colorectal and liver tumors. Mol Cell Biol 22: 1184-1193. (Pubitemid 34094854)
-
(2002)
Molecular and Cellular Biology
, vol.22
, Issue.4
, pp. 1184-1193
-
-
Lustig, B.1
Jerchow, B.2
Sachs, M.3
Weiler, S.4
Pietsch, T.5
Karsten, U.6
Van De, W.M.7
Clevers, H.8
Schlag, P.M.9
Birchmeier, W.10
Behrens, J.11
-
67
-
-
84859239880
-
A common role for various human truncated adenomatous polyposis coli isoforms in the control of Beta-catenin activity and cell proliferation
-
Vijaya-Chandra SH, Wacker I, Appelt UK, Behrens J, Schneikert J (2012) A common role for various human truncated adenomatous polyposis coli isoforms in the control of Beta-catenin activity and cell proliferation. PLoS One 7: e34479.
-
(2012)
PLoS One
, vol.7
-
-
Vijaya-Chandra, S.H.1
Wacker, I.2
Appelt, U.K.3
Behrens, J.4
Schneikert, J.5
-
68
-
-
0034711226
-
Inhibition of Wnt signaling pathway by a novel axin-binding protein
-
DOI 10.1074/jbc.M005984200
-
Kadoya T, Kishida S, Fukui A, Hinoi T, Michiue T, et al. (2000) Inhibition of Wnt signaling pathway by a novel Axin-binding protein. J Biol Chem 275: 37030-37037. (Pubitemid 32002119)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.47
, pp. 37030-37037
-
-
Kadoya, T.1
Kishida, S.2
Fukui, A.3
Hinoi, T.4
Michiue, T.5
Asashima, M.6
Kikuchi, A.7
-
69
-
-
0030999806
-
Armadillo coactivates transcription driven by the product of the Drosophila segment polarity gene dTCF
-
DOI 10.1016/S0092-8674(00)81925-X
-
van de Wetering M, Cavallo R, Dooijes D, van Beest M, van Es J, et al. (1997) Armadillo coactivates transcription driven by the product of the Drosophila segment polarity gene dTCF. Cell 88: 789-799. (Pubitemid 27164267)
-
(1997)
Cell
, vol.88
, Issue.6
, pp. 789-799
-
-
Van De, W.M.1
Cavallo, R.2
Dooijes, D.3
Van Beest, M.4
Van Es, J.5
Loureiro, J.6
Ypma, A.7
Hursh, D.8
Jones, T.9
Bejsovec, A.10
Peifer, M.11
Mortin, M.12
Clevers, H.13
-
70
-
-
0036166297
-
Wnt signals are transmitted through N-terminally dephosphorylated beta-catenin
-
DOI 10.1093/embo-reports/kvf002
-
Staal FJ, Noort MM, Strous GJ, Clevers HC (2002) Wnt signals are transmitted through N-terminally dephosphorylated beta-catenin. EMBO Rep 3: 63-68. (Pubitemid 34144817)
-
(2002)
EMBO Reports
, vol.3
, Issue.1
, pp. 63-68
-
-
Staal, F.J.T.1
Van Noort, M.2
Strous, G.J.3
Clevers, H.C.4
-
71
-
-
0022341148
-
Dissociation of Madin-Darby canine kidney epithelial cells by the monoclonal antibody anti-Arc-1: Mechanistic aspects and identification of the antigen as a component related to uvomorulin
-
DOI 10.1083/jcb.101.4.1307
-
Behrens J, Birchmeier W, Goodman SL, Imhof BA (1985) Dissociation of Madin-Darby canine kidney epithelial cells by the monoclonal antibody anti-arc-1: mechanistic aspects and identification of the antigen as a component related to uvomorulin. J Cell Biol 101: 1307-1315. (Pubitemid 16203747)
-
(1985)
Journal of Cell Biology
, vol.101
, Issue.4
, pp. 1307-1315
-
-
Behrens, J.1
Birchmeier, W.2
Goodman, S.L.3
Imhof, B.A.4
|