-
1
-
-
33845352555
-
Wnt signalling and the actin cytoskeleton
-
Akiyama T, Kawasaki Y. (2006). Wnt signalling and the actin cytoskeleton. Oncogene 25: 7538-7544.
-
(2006)
Oncogene
, vol.25
, pp. 7538-7544
-
-
Akiyama, T.1
Kawasaki, Y.2
-
2
-
-
0037096906
-
The 'just-right' signaling model: APC somatic mutations are selected based on a specific level of activation of the beta-catenin signaling cascade
-
Albuquerque C, Breukel C, van der Luijt R, Fidalgo P, Lage P, Slors FJ, et al. (2002). The 'just-right' signaling model: APC somatic mutations are selected based on a specific level of activation of the beta-catenin signaling cascade. Hum Mol Genet 11: 1549-1560.
-
(2002)
Hum Mol Genet
, vol.11
, pp. 1549-1560
-
-
Albuquerque, C.1
Breukel, C.2
Van Der Luijt, R.3
Fidalgo, P.4
Lage, P.5
Slors, F.J.6
-
3
-
-
35648988947
-
Adenomatous polyposis coli (APC): A multi-functional tumor suppressor gene
-
Aoki K, Taketo MM. (2007). Adenomatous polyposis coli (APC): a multi-functional tumor suppressor gene. J Cell Sci 120: 3327-3335.
-
(2007)
J Cell Sci
, vol.120
, pp. 3327-3335
-
-
Aoki, K.1
Taketo, M.M.2
-
4
-
-
59049106578
-
Crypt stem cells as the cells-of-origin of intestinal cancer
-
Barker N, Ridgway RA, van Es JH, van de Wetering M, Begthel H, van den Born M, et al. (2009). Crypt stem cells as the cells-of-origin of intestinal cancer. Nature 457: 608-611.
-
(2009)
Nature
, vol.457
, pp. 608-611
-
-
Barker, N.1
Ridgway, R.A.2
Van Es, J.H.3
Van De Wetering, M.4
Begthel, H.5
Van Den Born, M.6
-
5
-
-
0032562603
-
Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta
-
Behrens J, Jerchow BA, Wurtele M, Grimm J, Asbrand C, Wirtz R, et al. (1998). Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta. Science 280: 596-599.
-
(1998)
Science
, vol.280
, pp. 596-599
-
-
Behrens, J.1
Jerchow, B.A.2
Wurtele, M.3
Grimm, J.4
Asbrand, C.5
Wirtz, R.6
-
6
-
-
0029781509
-
Functional interaction of beta-catenin with the transcription factor LEF-1
-
Behrens J, von Kries JP, Kuhl M, Bruhn L, Wedlich D, Grosschedl R, et al. (1996). Functional interaction of beta-catenin with the transcription factor LEF-1. Nature 382: 638-642.
-
(1996)
Nature
, vol.382
, pp. 638-642
-
-
Behrens, J.1
Von Kries, J.P.2
Kuhl, M.3
Bruhn, L.4
Wedlich, D.5
Grosschedl, R.6
-
7
-
-
33845351678
-
Wnt signalling in the mouse intestine
-
Clarke AR. (2006). Wnt signalling in the mouse intestine. Oncogene 25: 7512-7521.
-
(2006)
Oncogene
, vol.25
, pp. 7512-7521
-
-
Clarke, A.R.1
-
8
-
-
33746808398
-
Wnt/beta-catenin signaling in development and disease
-
Clevers H. (2006). Wnt/beta-catenin signaling in development and disease. Cell 127: 469-480.
-
(2006)
Cell
, vol.127
, pp. 469-480
-
-
Clevers, H.1
-
9
-
-
0037699438
-
Refining the relation between 'first hits' and 'second hits' at the APC locus: The 'loose fit' model and evidence for differences in somatic mutation spectra among patients
-
Crabtree M, Sieber OM, Lipton L, Hodgson SV, Lamlum H, Thomas HJ, et al. (2003). Refining the relation between 'first hits' and 'second hits' at the APC locus: the 'loose fit' model and evidence for differences in somatic mutation spectra among patients. Oncogene 22: 4257-4265.
-
(2003)
Oncogene
, vol.22
, pp. 4257-4265
-
-
Crabtree, M.1
Sieber, O.M.2
Lipton, L.3
Hodgson, S.V.4
Lamlum, H.5
Thomas, H.J.6
-
10
-
-
0035890060
-
Molecular mechanisms of beta-catenin recognition by adenomatous polyposis coli revealed by the structure of an APC-beta-catenin complex
-
Eklof Spink K, Fridman SG, Weis WI. (2001). Molecular mechanisms of beta-catenin recognition by adenomatous polyposis coli revealed by the structure of an APC-beta-catenin complex. Embo J 20: 6203-6212.
-
(2001)
Embo J
, vol.20
, pp. 6203-6212
-
-
Eklof Spink, K.1
Fridman, S.G.2
Weis, W.I.3
-
11
-
-
35448947338
-
Chemical dissection of the APC Repeat 3 multistep phosphorylation by the concerted action of protein kinases CK1 and GSK3
-
Ferrarese A, Marin O, Bustos VH, Venerando A, Antonelli M, Allende JE, et al. (2007). Chemical dissection of the APC Repeat 3 multistep phosphorylation by the concerted action of protein kinases CK1 and GSK3. Biochemistry 46: 11902-11910.
-
(2007)
Biochemistry
, vol.46
, pp. 11902-11910
-
-
Ferrarese, A.1
Marin, O.2
Bustos, V.H.3
Venerando, A.4
Antonelli, M.5
Allende, J.E.6
-
12
-
-
33847740988
-
Wnt/beta-catenin signaling in cancer stemness and malignant behavior
-
Fodde R, Brabletz T. (2007). Wnt/beta-catenin signaling in cancer stemness and malignant behavior. Curr Opin Cell Biol 19: 150-158.
-
(2007)
Curr Opin Cell Biol
, vol.19
, pp. 150-158
-
-
Fodde, R.1
Brabletz, T.2
-
13
-
-
68249083454
-
A targeted constitutive mutation in the APC tumor suppressor gene underlies mammary but not intestinal tumori-genesis
-
Gaspar C, Franken P, Molenaar L, Breukel C, van der Valk M, Smits R, et al. (2009). A targeted constitutive mutation in the APC tumor suppressor gene underlies mammary but not intestinal tumori-genesis. PLoS Genet 5: e1000547.
-
(2009)
PLoS Genet
, vol.5
-
-
Gaspar, C.1
Franken, P.2
Molenaar, L.3
Breukel, C.4
Van Der Valk, M.5
Smits, R.6
-
14
-
-
0027401792
-
Mutational analysis of patients with adenomatous polyposis: Identical inactivating mutations in unrelated individuals
-
Groden J, Gelbert L, Thliveris A, Nelson L, Robertson M, Joslyn G, et al. (1993). Mutational analysis of patients with adenomatous polyposis: identical inactivating mutations in unrelated individuals. Am J Hum Genet 52: 263-272.
-
(1993)
Am J Hum Genet
, vol.52
, pp. 263-272
-
-
Groden, J.1
Gelbert, L.2
Thliveris, A.3
Nelson, L.4
Robertson, M.5
Joslyn, G.6
-
15
-
-
0025938038
-
Identification and characterization of the familial adenomatous polyposis coli gene
-
Groden J, Thliveris A, Samowitz W, Carlson M, Gelbert L, Albertsen H, et al. (1991). Identification and characterization of the familial adenomatous polyposis coli gene. Cell 66: 589-600.
-
(1991)
Cell
, vol.66
, pp. 589-600
-
-
Groden, J.1
Thliveris, A.2
Samowitz, W.3
Carlson, M.4
Gelbert, L.5
Albertsen, H.6
-
16
-
-
0036089371
-
Mutation cluster region, association between germline and somatic mutations and genotype-phenotype correlation in upper gastrointestinal familial adenomatous polyposis
-
Groves C, Lamlum H, Crabtree M, Williamson J, Taylor C, Bass S, et al. (2002). Mutation cluster region, association between germline and somatic mutations and genotype-phenotype correlation in upper gastrointestinal familial adenomatous polyposis. Am J Pathol 160: 2055-2061.
-
(2002)
Am J Pathol
, vol.160
, pp. 2055-2061
-
-
Groves, C.1
Lamlum, H.2
Crabtree, M.3
Williamson, J.4
Taylor, C.5
Bass, S.6
-
17
-
-
0030890994
-
High frequency in vivo loss of heterozygosity is primarily a consequence of mitotic recombination
-
Gupta PK, Sahota A, Boyadjiev SA, Bye S, Shao C, O'Neill JP, et al. (1997). High frequency in vivo loss of heterozygosity is primarily a consequence of mitotic recombination. Cancer Res 57: 1188-1193.
-
(1997)
Cancer Res
, vol.57
, pp. 1188-1193
-
-
Gupta, P.K.1
Sahota, A.2
Boyadjiev, S.A.3
Bye, S.4
Shao, C.5
O'Neill, J.P.6
-
18
-
-
4344562126
-
Mechanism of phosphorylation-dependent binding of APC to beta-catenin and its role in beta-catenin degradation
-
Ha NC, Tonozuka T, Stamos JL, Choi HJ, Weis WI. (2004). Mechanism of phosphorylation-dependent binding of APC to beta-catenin and its role in beta-catenin degradation. Mol Cell 15: 511-521.
-
(2004)
Mol Cell
, vol.15
, pp. 511-521
-
-
Ha, N.C.1
Tonozuka, T.2
Stamos, J.L.3
Choi, H.J.4
Weis, W.I.5
-
19
-
-
0037229064
-
A Robertsonian translocation suppresses a somatic recombination pathway to loss of hetero-zygosity
-
Haigis KM, Dove WF. (2003). A Robertsonian translocation suppresses a somatic recombination pathway to loss of hetero-zygosity. Nat Genet 33: 33-39.
-
(2003)
Nat Genet
, vol.33
, pp. 33-39
-
-
Haigis, K.M.1
Dove, W.F.2
-
20
-
-
33845411722
-
Protecting genomic integrity in somatic cells and embryonic stem cells
-
Hong Y, Cervantes RB, Tichy E, Tischfield JA, Stambrook PJ. (2007). Protecting genomic integrity in somatic cells and embryonic stem cells. Mutat Res 614: 48-55.
-
(2007)
Mutat Res
, vol.614
, pp. 48-55
-
-
Hong, Y.1
Cervantes, R.B.2
Tichy, E.3
Tischfield, J.A.4
Stambrook, P.J.5
-
21
-
-
0034708763
-
Down-regulation of beta-catenin by the colorectal tumor suppressor APC requires association with Axin and beta-catenin
-
Kawahara K, Morishita T, Nakamura T, Hamada F, Toyoshima K, Akiyama T. (2000). Down-regulation of beta-catenin by the colorectal tumor suppressor APC requires association with Axin and beta-catenin. J Biol Chem 275: 8369-8374.
-
(2000)
J Biol Chem
, vol.275
, pp. 8369-8374
-
-
Kawahara, K.1
Morishita, T.2
Nakamura, T.3
Hamada, F.4
Toyoshima, K.5
Akiyama, T.6
-
22
-
-
33845351956
-
Beta-catenin destruction complex: Insights and questions from a structural perspective
-
Kimelman D, Xu W. (2006). beta-catenin destruction complex: insights and questions from a structural perspective. Oncogene 25: 7482-7491.
-
(2006)
Oncogene
, vol.25
, pp. 7482-7491
-
-
Kimelman, D.1
Xu, W.2
-
23
-
-
58049196841
-
Beta-catenin degradation mediated by the CID domain of APC provides a model for the selection of APC mutations in colorectal, desmoid and duodenal tumours
-
Kohler EM, Chandra SH, Behrens J, Schneikert J. (2009). Beta-catenin degradation mediated by the CID domain of APC provides a model for the selection of APC mutations in colorectal, desmoid and duodenal tumours. Hum Mol Genet 18: 213-226.
-
(2009)
Hum Mol Genet
, vol.18
, pp. 213-226
-
-
Kohler, E.M.1
Chandra, S.H.2
Behrens, J.3
Schneikert, J.4
-
24
-
-
45749140081
-
Functional definition of the mutation cluster region of adenomatous polyposis coli in colorectal tumours
-
Kohler EM, Derungs A, Daum G, Behrens J, Schneikert J. (2008). Functional definition of the mutation cluster region of adenomatous polyposis coli in colorectal tumours. Hum Mol Genet 17: 1978-1987.
-
(2008)
Hum Mol Genet
, vol.17
, pp. 1978-1987
-
-
Kohler, E.M.1
Derungs, A.2
Daum, G.3
Behrens, J.4
Schneikert, J.5
-
26
-
-
33646583259
-
Nucleo-cytoplasmic distribution of \{beta\}-catenin is re
-
Krieghoff E, Behrens J, Mayr B. (2006). Nucleo-cytoplasmic distribution of \{beta\}-catenin is re. J Cell Sci 119: 1453-1463.
-
(2006)
J Cell Sci
, vol.119
, pp. 1453-1463
-
-
Krieghoff, E.1
Behrens, J.2
Mayr, B.3
-
27
-
-
61449101684
-
Genetic mechanisms in Apc-mediated mammary tumorigenesis
-
Kuraguchi M, Ohene-Baah NY, Sonkin D, Bronson RT, Kucherlapati R. (2009). Genetic mechanisms in Apc-mediated mammary tumorigenesis. PLoS Genet 5: e1000367.
-
(2009)
PLoS Genet
, vol.5
-
-
Kuraguchi, M.1
Ohene-Baah, N.Y.2
Sonkin, D.3
Bronson, R.T.4
Kucherlapati, R.5
-
28
-
-
0032823133
-
The type of somatic mutation at APC in familial adenomatous polyposis is determined by the site of the germline mutation: A new facet to Knudson's 'two-hit' hypothesis
-
Lamlum H, Ilyas M, Rowan A, Clark S, Johnson V, Bell J, et al. (1999). The type of somatic mutation at APC in familial adenomatous polyposis is determined by the site of the germline mutation: a new facet to Knudson's 'two-hit' hypothesis. Nat Med 5: 1071-1075.
-
(1999)
Nat Med
, vol.5
, pp. 1071-1075
-
-
Lamlum, H.1
Ilyas, M.2
Rowan, A.3
Clark, S.4
Johnson, V.5
Bell, J.6
-
29
-
-
33846509424
-
APC mutations in FAP-associated desmoid tumours are non-random but not 'just right'
-
Latchford A, Volikos E, Johnson V, Rogers P, Suraweera N, Tomlinson I, et al. (2007). APC mutations in FAP-associated desmoid tumours are non-random but not 'just right'. Hum Mol Genet 16: 78-82.
-
(2007)
Hum Mol Genet
, vol.16
, pp. 78-82
-
-
Latchford, A.1
Volikos, E.2
Johnson, V.3
Rogers, P.4
Suraweera, N.5
Tomlinson, I.6
-
30
-
-
0037155691
-
Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism
-
Liu C, Li Y, Semenov M, Han C, Baeg GH, Tan Y, et al. (2002). Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism. Cell 108: 837-847.
-
(2002)
Cell
, vol.108
, pp. 837-847
-
-
Liu, C.1
Li, Y.2
Semenov, M.3
Han, C.4
Baeg, G.H.5
Tan, Y.6
-
31
-
-
33745276261
-
The third 20 amino acid repeat is the tightest binding site of APC for beta-catenin
-
Liu J, Xing Y, Hinds TR, Zheng J, Xu W. (2006). The third 20 amino acid repeat is the tightest binding site of APC for beta-catenin. J Mol Biol 360: 133-144.
-
(2006)
J Mol Biol
, vol.360
, pp. 133-144
-
-
Liu, J.1
Xing, Y.2
Hinds, T.R.3
Zheng, J.4
Xu, W.5
-
32
-
-
41549117418
-
Cell regulation by the Apc protein Apc as master regulator of epithelia
-
McCartney BM, Nathke IS. (2008). Cell regulation by the Apc protein Apc as master regulator of epithelia. Curr Opin Cell Biol 20: 186-193.
-
(2008)
Curr Opin Cell Biol
, vol.20
, pp. 186-193
-
-
McCartney, B.M.1
Nathke, I.S.2
-
33
-
-
37448999323
-
Functional characterization of the novel APC N1026S variant associated with attenuated familial adenoma-tous polyposis
-
Menendez M, Gonzalez S, Obrador-Hevia A, Dominguez A, Pujol MJ, Valls J, et al. (2008). Functional characterization of the novel APC N1026S variant associated with attenuated familial adenoma-tous polyposis. Gastroenterology 134: 56-64.
-
(2008)
Gastroenterology
, vol.134
, pp. 56-64
-
-
Menendez, M.1
Gonzalez, S.2
Obrador-Hevia, A.3
Dominguez, A.4
Pujol, M.J.5
Valls, J.6
-
34
-
-
0028291928
-
Characteristics of somatic mutation of the adenomatous polyposis coli gene in colorectal tumors
-
Miyaki M, Konishi M, Kikuchi-Yanoshita R, Enomoto M, Igari T, Tanaka K, et al. (1994). Characteristics of somatic mutation of the adenomatous polyposis coli gene in colorectal tumors. Cancer Res 54: 3011-3020.
-
(1994)
Cancer Res
, vol.54
, pp. 3011-3020
-
-
Miyaki, M.1
Konishi, M.2
Kikuchi-Yanoshita, R.3
Enomoto, M.4
Igari, T.5
Tanaka, K.6
-
35
-
-
42549132671
-
Difference in characteristics of APC mutations between colonic and extracolonic tumors of FAP patients: Variations with phenotype
-
Miyaki M, Yamaguchi T, Iijima T, Takahashi K, Matsumoto H, Yasutome M, et al. (2008). Difference in characteristics of APC mutations between colonic and extracolonic tumors of FAP patients: variations with phenotype. Int J Cancer 122: 2491-2497.
-
(2008)
Int J Cancer
, vol.122
, pp. 2491-2497
-
-
Miyaki, M.1
Yamaguchi, T.2
Iijima, T.3
Takahashi, K.4
Matsumoto, H.5
Yasutome, M.6
-
36
-
-
0026894053
-
Somatic mutations of the APC gene in colorectal tumors: Mutation cluster region in the APC gene
-
Miyoshi Y, Nagase H, Ando H, Horii A, Ichii S, Nakatsuru S, et al. (1992). Somatic mutations of the APC gene in colorectal tumors: mutation cluster region in the APC gene. Hum Mol Genet 1: 229-233.
-
(1992)
Hum Mol Genet
, vol.1
, pp. 229-233
-
-
Miyoshi, Y.1
Nagase, H.2
Ando, H.3
Horii, A.4
Ichii, S.5
Nakatsuru, S.6
-
37
-
-
0028987249
-
Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein
-
Munemitsu S, Albert I, Souza B, Rubinfeld B, Polakis P. (1995). Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein. Proc Natl Acad Sci USA 92: 3046-3050.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 3046-3050
-
-
Munemitsu, S.1
Albert, I.2
Souza, B.3
Rubinfeld, B.4
Polakis, P.5
-
38
-
-
33845234807
-
Cytoskeleton out of the cupboard: Colon cancer and cytoskeletal changes induced by loss of APC
-
Nathke I. (2006). Cytoskeleton out of the cupboard: colon cancer and cytoskeletal changes induced by loss of APC. Nat Rev Cancer 6: 967-974.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 967-974
-
-
Nathke, I.1
-
39
-
-
0027417312
-
Germ-line mutations in the first 14 exons of the adenomatous polyposis coli (APC) gene
-
Olschwang S, Laurent-Puig P, Groden J, White R, Thomas G. (1993). Germ-line mutations in the first 14 exons of the adenomatous polyposis coli (APC) gene. Am J Hum Genet 52: 273-279.
-
(1993)
Am J Hum Genet
, vol.52
, pp. 273-279
-
-
Olschwang, S.1
Laurent-Puig, P.2
Groden, J.3
White, R.4
Thomas, G.5
-
40
-
-
48949115368
-
Unexpectedly robust assembly of the Axin destruction complex regulates Wnt/Wg signaling in Drosophila as revealed by analysis in vivo
-
Peterson-Nedry W, Erdeniz N, Kremer S, Yu J, Baig-Lewis S, Wehrli M. (2008). Unexpectedly robust assembly of the Axin destruction complex regulates Wnt/Wg signaling in Drosophila as revealed by analysis in vivo. Dev Biol 320: 226-241.
-
(2008)
Dev Biol
, vol.320
, pp. 226-241
-
-
Peterson-Nedry, W.1
Erdeniz, N.2
Kremer, S.3
Yu, J.4
Baig-Lewis, S.5
Wehrli, M.6
-
41
-
-
33846193290
-
The many ways of Wnt in cancer
-
Polakis P. (2007). The many ways of Wnt in cancer. Curr Opin Genet Dev 17: 45-51.
-
(2007)
Curr Opin Genet Dev
, vol.17
, pp. 45-51
-
-
Polakis, P.1
-
42
-
-
66449123118
-
The APC1322T mouse develops severe polyposis associated with submaximal nuclear beta-catenin expression
-
Pollard P, Deheragoda M, Segditsas S, Lewis A, Rowan A, Howarth K, et al. (2009). The APC1322T mouse develops severe polyposis associated with submaximal nuclear beta-catenin expression. Gastroenterology 136: 2204-2213.
-
(2009)
Gastroenterology
, vol.136
, pp. 2204-2213
-
-
Pollard, P.1
Deheragoda, M.2
Segditsas, S.3
Lewis, A.4
Rowan, A.5
Howarth, K.6
-
43
-
-
0026630266
-
APC mutations occur early during colorectal tumorigenesis
-
Powell SM, Zilz N, Beazer-Barclay Y, Bryan TM, Hamilton SR, Thibodeau SN, et al. (1992). APC mutations occur early during colorectal tumorigenesis. Nature 359: 235-237.
-
(1992)
Nature
, vol.359
, pp. 235-237
-
-
Powell, S.M.1
Zilz, N.2
Beazer-Barclay, Y.3
Bryan, T.M.4
Hamilton, S.R.5
Thibodeau, S.N.6
-
44
-
-
0034724186
-
APC mutations in sporadic colorectal tumors: A mutational 'hotspot' and interdependence of the 'two hits'
-
Rowan AJ, Lamlum H, Ilyas M, Wheeler J, Straub J, Papadopoulou A, et al. (2000). APC mutations in sporadic colorectal tumors: A mutational 'hotspot' and interdependence of the 'two hits'. Proc Natl Acad Sci USA 97: 3352-3357.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 3352-3357
-
-
Rowan, A.J.1
Lamlum, H.2
Ilyas, M.3
Wheeler, J.4
Straub, J.5
Papadopoulou, A.6
-
45
-
-
0030871048
-
Loss of beta-catenin regulation by the APC tumor suppressor protein correlates with loss of structure due to common somatic mutations of the gene
-
Rubinfeld B, Albert I, Porfiri E, Munemitsu S, Polakis P. (1997). Loss of beta-catenin regulation by the APC tumor suppressor protein correlates with loss of structure due to common somatic mutations of the gene. Cancer Res 57: 4624-4630.
-
(1997)
Cancer Res
, vol.57
, pp. 4624-4630
-
-
Rubinfeld, B.1
Albert, I.2
Porfiri, E.3
Munemitsu, S.4
Polakis, P.5
-
46
-
-
0027738023
-
Association of the APC gene product with beta-catenin
-
Rubinfeld B, Souza B, Albert I, Muller O, Chamberlain SH, Masiarz FR, et al. (1993). Association of the APC gene product with beta-catenin. Science 262: 1731-1734.
-
(1993)
Science
, vol.262
, pp. 1731-1734
-
-
Rubinfeld, B.1
Souza, B.2
Albert, I.3
Muller, O.4
Chamberlain, S.H.5
Masiarz, F.R.6
-
47
-
-
33646498125
-
Truncated APC is required for cell proliferation and DNA replication
-
Schneikert J, Behrens J. (2006). Truncated APC is required for cell proliferation and DNA replication. Int J Cancer 119: 74-79.
-
(2006)
Int J Cancer
, vol.119
, pp. 74-79
-
-
Schneikert, J.1
Behrens, J.2
-
48
-
-
33847397617
-
The canonical Wnt signalling pathway and its APC partner in colon cancer development
-
Schneikert J, Behrens J. (2007a). The canonical Wnt signalling pathway and its APC partner in colon cancer development. Gut 56: 417-425.
-
(2007)
Gut
, vol.56
, pp. 417-425
-
-
Schneikert, J.1
Behrens, J.2
-
49
-
-
33846626414
-
Truncated APC regulates the transcriptional activity of beta-catenin in a cell cycle dependent manner
-
Schneikert J, Grohmann A, Behrens J. (2007b). Truncated APC regulates the transcriptional activity of beta-catenin in a cell cycle dependent manner. Hum Mol Genet 16: 199-209.
-
(2007)
Hum Mol Genet
, vol.16
, pp. 199-209
-
-
Schneikert, J.1
Grohmann, A.2
Behrens, J.3
-
50
-
-
33845373278
-
Colorectal cancer and genetic alterations in the Wnt pathway
-
Segditsas S, Tomlinson I. (2006). Colorectal cancer and genetic alterations in the Wnt pathway. Oncogene 25: 7531-7537.
-
(2006)
Oncogene
, vol.25
, pp. 7531-7537
-
-
Segditsas, S.1
Tomlinson, I.2
-
51
-
-
0033563226
-
APC1638T: A mouse model delineating critical domains of the adenomatous polyposis coli protein involved in tumorigenesis and development
-
Smits R, Kielman MF, Breukel C, Zurcher C, Neufeld K, Jagmohan-Changur S, et al. (1999). APC1638T: a mouse model delineating critical domains of the adenomatous polyposis coli protein involved in tumorigenesis and development. Genes Dev 13: 1309-1321.
-
(1999)
Genes Dev
, vol.13
, pp. 1309-1321
-
-
Smits, R.1
Kielman, M.F.2
Breukel, C.3
Zurcher, C.4
Neufeld, K.5
Jagmohan-Changur, S.6
-
52
-
-
0036166297
-
Wnt signals are transmitted through N-terminally dephosphorylated beta-catenin
-
Staal FJ, Noort Mv M, Strous GJ, Clevers HC. (2002). Wnt signals are transmitted through N-terminally dephosphorylated beta-catenin. EMBO Rep 3: 63-68.
-
(2002)
EMBO Rep
, vol.3
, pp. 63-68
-
-
Staal, F.J.1
Noort Mv, M.2
Strous, G.J.3
Clevers, H.C.4
-
53
-
-
0027756014
-
Association of the APC tumor suppressor protein with catenins
-
Su LK, Vogelstein B, Kinzler KW. (1993). Association of the APC tumor suppressor protein with catenins. Science 262: 1734-1737.
-
(1993)
Science
, vol.262
, pp. 1734-1737
-
-
Su, L.K.1
Vogelstein, B.2
Kinzler, K.W.3
-
54
-
-
33845352215
-
Wnt signaling and gastrointestinal tumorigenesis in mouse models
-
Taketo MM. (2006). Wnt signaling and gastrointestinal tumorigenesis in mouse models. Oncogene 25: 7522-7530.
-
(2006)
Oncogene
, vol.25
, pp. 7522-7530
-
-
Taketo, M.M.1
-
55
-
-
0037459238
-
Differences between the interaction of beta-catenin with non-phosphorylated and single-mimicked phosphorylated 20-amino acid residue repeats of the APC protein
-
Tickenbrock L, Kossmeier K, Rehmann H, Herrmann C, Muller O. (2003). Differences between the interaction of beta-catenin with non-phosphorylated and single-mimicked phosphorylated 20-amino acid residue repeats of the APC protein. J Mol Biol 327: 359-367.
-
(2003)
J Mol Biol
, vol.327
, pp. 359-367
-
-
Tickenbrock, L.1
Kossmeier, K.2
Rehmann, H.3
Herrmann, C.4
Muller, O.5
-
56
-
-
0030999806
-
Armadillo coactivates transcription driven by the product of the Drosophila segment polarity gene dTCF
-
van de Wetering M, Cavallo R, Dooijes D, van Beest M, van Es J, Loureiro J, et al. (1997). Armadillo coactivates transcription driven by the product of the Drosophila segment polarity gene dTCF. Cell 88: 789-799.
-
(1997)
Cell
, vol.88
, pp. 789-799
-
-
Van De Wetering, M.1
Cavallo, R.2
Dooijes, D.3
Van Beest, M.4
Van Es, J.5
Loureiro, J.6
-
57
-
-
0344442773
-
Crystal structure of a beta-catenin/axin complex suggests a mechanism for the beta-catenin destruction complex
-
Xing Y, Clemens WK, Kimelman D, Xu W. (2003). Crystal structure of a beta-catenin/axin complex suggests a mechanism for the beta-catenin destruction complex. Genes Dev 17: 2753-2764.
-
(2003)
Genes Dev
, vol.17
, pp. 2753-2764
-
-
Xing, Y.1
Clemens, W.K.2
Kimelman, D.3
Xu, W.4
-
58
-
-
4344684495
-
Crystal structure of a beta-catenin/ APC complex reveals a critical role for APC phosphorylation in APC function
-
Xing Y, Clements WK, Le Trong I, Hinds TR, Stenkamp R, Kimelman D, et al. (2004). Crystal structure of a beta-catenin/ APC complex reveals a critical role for APC phosphorylation in APC function. Mol Cell 15: 523-533.
-
(2004)
Mol Cell
, vol.15
, pp. 523-533
-
-
Xing, Y.1
Clements, W.K.2
Le Trong, I.3
Hinds, T.R.4
Stenkamp, R.5
Kimelman, D.6
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