Crtc1 activates a transcriptional program deregulated at early Alzheimer's disease-related stages

Journal of Neuroscience

Volumn 34, Issue 17, 2014, Pages 5776-5787

  Parra Damas, Arnaldo ^a,b   Valero, Jorge ^a,b,d   Chen, Meng ^a,b   España, Judit ^a,b   Martín, Elsa ^a,b   Ferrer, Isidro ^b,c   Rodríguez Alvarez, José ^a,b   Saura, Carlos A ^a,b  

^a INSTITUT DE NEUROCIÈNCIES   (Spain)

^b CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED SOBRE ENFERMEDADES NEURODEGENERATIVAS CIBERNED   (Spain)

^c HOSPITAL UNIVERSITARI DE BELLVITGE   (Spain)

^d UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

CREB; Gene expression; Memory; Neurodegeneration; TORC; amyloid

Indexed keywords

ALPHA ACTIN; ALPHA SECRETASE; AMYLOID PRECURSOR PROTEIN; BETA ACTIN; BETA SECRETASE; BRAIN DERIVED NEUROTROPHIC FACTOR; CHROMOGRANIN A; CREB REGULATED TRANSCRIPTION COACTIVATOR 1; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYSTEINE RICH PROTEIN 61; CYTIDINE TRIPHOSPHATE; GAMMA SECRETASE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; LAMIN B; MICROTUBULE ASSOCIATED PROTEIN 2; NERVE GROWTH FACTOR BETA SUBUNIT; NEUROFILAMENT PROTEIN; NUCLEAR RECEPTOR COACTIVATOR; NUCLEAR RECEPTOR NUR77; NUCLEAR RECEPTOR RELATED FACTOR 1; PEPTIDYLPROLYL ISOMERASE; PROTEIN C FOS; SECRETOGRANIN II; SHORT HAIRPIN RNA; SYNAPTOTAGMIN; TATA BINDING PROTEIN; TRANSCRIPTION FACTOR EGR 1; TRANSCRIPTOME; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ALZHEIMER DISEASE; AMNESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DEREGULATION; DOWN REGULATION; GENE MUTATION; GENE OVEREXPRESSION; GENE REGULATORY NETWORK; GENE TRANSLOCATION; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; INTRACELLULAR SIGNALING; MALE; MOUSE; MRNA EXPRESSION ASSAY; NERVE CELL PLASTICITY; NEUROTRANSMISSION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN MICROARRAY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; SPATIAL LEARNING; SPATIAL MEMORY; TRANSCRIPTION REGULATION; WESTERN BLOTTING;

CREB; GENE EXPRESSION; MEMORY; NEURODEGENERATION; TORC; Β-AMYLOID;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BEHAVIOR, ANIMAL; HIPPOCAMPUS; HUMANS; MAZE LEARNING; MEMORY; MICE; MICE, TRANSGENIC; NEURONAL PLASTICITY; NEURONS; SYNAPTIC TRANSMISSION; TRANSCRIPTION FACTORS;

EID: 84899493751     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5288-13.2014     Document Type: Article

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