-
1
-
-
83455220200
-
From stem cell to red cell: Regulation of erythropoiesis at multiple levels by multiple proteins, RNAs, and chromatin modifications
-
Hattangadi SM, Wong P, Zhang L, et al. From stem cell to red cell: regulation of erythropoiesis at multiple levels by multiple proteins, RNAs, and chromatin modifications. Blood 2011; 118:6258-6268.
-
(2011)
Blood
, vol.118
, pp. 6258-6268
-
-
Hattangadi, S.M.1
Wong, P.2
Zhang, L.3
-
2
-
-
39049103889
-
Ontogeny of erythropoiesis in the mammalian embryo
-
McGrath K, Palis J. Ontogeny of erythropoiesis in the mammalian embryo. Curr Top Dev Biol 2008; 82:1-22.
-
(2008)
Curr Top Dev Biol
, vol.82
, pp. 1-22
-
-
McGrath, K.1
Palis, J.2
-
3
-
-
84863986133
-
Functions of DNA methylation: Islands, start sites, gene bodies and beyond
-
Jones PA. Functions of DNA methylation: islands, start sites, gene bodies and beyond. Nat Rev Genet 2012; 13:484-492.
-
(2012)
Nat Rev Genet
, vol.13
, pp. 484-492
-
-
Jones, P.A.1
-
4
-
-
0024417073
-
The erythroid-specific transcription factor Eryf1: A new finger protein
-
Evans T, Felsenfeld G. The erythroid-specific transcription factor Eryf1: a new finger protein. Cell 1989; 58:877-885.
-
(1989)
Cell
, vol.58
, pp. 877-885
-
-
Evans, T.1
Felsenfeld, G.2
-
5
-
-
0024373139
-
Cloning of cDNA for the major DNA-binding protein of the erythroid lineage through expression in mammalian cells
-
Tsai SF, Martin DI, Zon LI, et al. Cloning of cDNA for the major DNA-binding protein of the erythroid lineage through expression in mammalian cells. Nature 1989; 339:446-451.
-
(1989)
Nature
, vol.339
, pp. 446-451
-
-
Tsai, S.F.1
Martin, D.I.2
Zon, L.I.3
-
6
-
-
0027211845
-
A novel, erythroid cell-specific murine transcription factor that binds to the CACCC element and is related to the Kruppel family of nuclear proteins
-
Miller IJ, Bieker JJ. A novel, erythroid cell-specific murine transcription factor that binds to the CACCC element and is related to the Kruppel family of nuclear proteins. Mol Cell Biol 1993; 13:2776-2786.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 2776-2786
-
-
Miller, I.J.1
Bieker, J.J.2
-
7
-
-
0028022916
-
An early haematopoietic defect in mice lacking the transcription factor GATA-2
-
Tsai FY, Keller G, Kuo FC, et al. An early haematopoietic defect in mice lacking the transcription factor GATA-2. Nature 1994; 371:221-226.
-
(1994)
Nature
, vol.371
, pp. 221-226
-
-
Tsai, F.Y.1
Keller, G.2
Kuo, F.C.3
-
8
-
-
0030926190
-
Transcription factor GATA-2 is required for proliferation/survival of early hematopoietic cells and mast cell formation, but not for erythroid and myeloid terminal differentiation
-
Tsai FY, Orkin SH. Transcription factor GATA-2 is required for proliferation/survival of early hematopoietic cells and mast cell formation, but not for erythroid and myeloid terminal differentiation. Blood 1997; 89:3636-3643.
-
(1997)
Blood
, vol.89
, pp. 3636-3643
-
-
Tsai, F.Y.1
Orkin, S.H.2
-
9
-
-
0029918597
-
Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis
-
Wang Q, Stacy T, Binder M, et al. Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis. Proc Natl Acad Sci USA 1996; 93:3444-3449.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 3444-3449
-
-
Wang, Q.1
Stacy, T.2
Binder, M.3
-
10
-
-
0030061554
-
AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis
-
Okuda T, van Deursen J, Hiebert SW, et al. AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis. Cell 1996; 84:321-330.
-
(1996)
Cell
, vol.84
, pp. 321-330
-
-
Okuda, T.1
Van Deursen, J.2
Hiebert, S.W.3
-
11
-
-
0028858855
-
Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCL
-
Shivdasani RA, Mayer EL, Orkin SH. Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCL. Nature 1995; 373:432-434.
-
(1995)
Nature
, vol.373
, pp. 432-434
-
-
Shivdasani, R.A.1
Mayer, E.L.2
Orkin, S.H.3
-
12
-
-
22544471496
-
Functional but abnormal adult erythropoiesis in the absence of the stem cell leukemia gene
-
Hall MA, Slater NJ, Salmon JM, et al. Functional but abnormal adult erythropoiesis in the absence of the stem cell leukemia gene. Mol Cell Biol 2005; 25:6355-6362.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 6355-6362
-
-
Hall, M.A.1
Slater, N.J.2
Salmon, J.M.3
-
13
-
-
84865755978
-
The accessible chromatin landscape of the human genome
-
Thurman RE, Rynes E, Humbert R, et al. The accessible chromatin landscape of the human genome. Nature 2012; 489:75-82.
-
(2012)
Nature
, vol.489
, pp. 75-82
-
-
Thurman, R.E.1
Rynes, E.2
Humbert, R.3
-
15
-
-
84865708757
-
An expansive human regulatory lexicon encoded in transcription factor footprints
-
Neph S, Vierstra J, Stergachis AB, et al. An expansive human regulatory lexicon encoded in transcription factor footprints. Nature 2012; 489:83-90.
-
(2012)
Nature
, vol.489
, pp. 83-90
-
-
Neph, S.1
Vierstra, J.2
Stergachis, A.B.3
-
16
-
-
84865790047
-
An integrated encyclopedia of DNA elements in the human genome
-
Consortium EP, Dunham I, Kundaje A, et al. An integrated encyclopedia of DNA elements in the human genome. Nature 2012; 489:57-74.
-
(2012)
Nature
, vol.489
, pp. 57-74
-
-
Consortium, E.P.1
Dunham, I.2
Kundaje, A.3
-
17
-
-
84864462544
-
A map of the cis-regulatory sequences in the mouse genome
-
Shen Y, Yue F, McCleary DF, et al. A map of the cis-regulatory sequences in the mouse genome. Nature 2012; 488:116-120.
-
(2012)
Nature
, vol.488
, pp. 116-120
-
-
Shen, Y.1
Yue, F.2
McCleary, D.F.3
-
18
-
-
70449675049
-
Discovering hematopoietic mechanisms through genome-wide analysis of GATA factor chromatin occupancy
-
Fujiwara T, O'Geen H, Keles S, et al. Discovering hematopoietic mechanisms through genome-wide analysis of GATA factor chromatin occupancy. Mol Cell 2009; 36:667-681.
-
(2009)
Mol Cell
, vol.36
, pp. 667-681
-
-
Fujiwara, T.1
O'Geen, H.2
Keles, S.3
-
19
-
-
84863011357
-
Autophagy driven by a master regulator of hematopoiesis
-
Kang YA, Sanalkumar R, O'Geen H, et al. Autophagy driven by a master regulator of hematopoiesis. Mol Cell Biol 2012; 32:226-239.
-
(2012)
Mol Cell Biol
, vol.32
, pp. 226-239
-
-
Kang, Y.A.1
Sanalkumar, R.2
O'Geen, H.3
-
20
-
-
70449638281
-
Insights into GATA-1-mediated gene activation versus repression via genome-wide chromatin occupancy analysis
-
Yu M, Riva L, Xie H, et al. Insights into GATA-1-mediated gene activation versus repression via genome-wide chromatin occupancy analysis. Mol Cell 2009; 36:682-695.
-
(2009)
Mol Cell
, vol.36
, pp. 682-695
-
-
Yu, M.1
Riva, L.2
Xie, H.3
-
21
-
-
70449696134
-
Erythroid GATA1 function revealed by genome-wide analysis of transcription factor occupancy, histone modifications, and mRNA expression
-
Cheng Y, Wu W, Kumar SA, et al. Erythroid GATA1 function revealed by genome-wide analysis of transcription factor occupancy, histone modifications, and mRNA expression. Genome Res 2009; 19:2172-2184.
-
(2009)
Genome Res
, vol.19
, pp. 2172-2184
-
-
Cheng, Y.1
Wu, W.2
Kumar, S.A.3
-
22
-
-
73249141252
-
Primary sequence and epigenetic determinants of in vivo occupancy of genomic DNA by GATA1
-
Zhang Y, Wu W, Cheng Y, et al. Primary sequence and epigenetic determinants of in vivo occupancy of genomic DNA by GATA1. Nucleic Acids Res 2009; 37:7024-7038.
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 7024-7038
-
-
Zhang, Y.1
Wu, W.2
Cheng, Y.3
-
23
-
-
84865353203
-
Cofactor-mediated restriction of GATA-1 chromatin occupancy coordinates lineage-specific gene expression
-
Chlon TM, Dore LC, Crispino JD. Cofactor-mediated restriction of GATA-1 chromatin occupancy coordinates lineage-specific gene expression. Mol Cell 2012; 47:608-621.
-
(2012)
Mol Cell
, vol.47
, pp. 608-621
-
-
Chlon, T.M.1
Dore, L.C.2
Crispino, J.D.3
-
24
-
-
77955155544
-
A global role for KLF1 in erythropoiesis revealed by ChIP-seq in primary erythroid cells
-
Tallack MR, Whitington T, Yuen WS, et al. A global role for KLF1 in erythropoiesis revealed by ChIP-seq in primary erythroid cells. Genome Res 2010; 20:1052-1063.
-
(2010)
Genome Res
, vol.20
, pp. 1052-1063
-
-
Tallack, M.R.1
Whitington, T.2
Yuen, W.S.3
-
25
-
-
80053559720
-
Genome-wide ChIP-Seq reveals a dramatic shift in the binding of the transcription factor erythroid Kruppel-like factor during erythrocyte differentiation
-
Pilon AM, Ajay SS, Kumar SA, et al. Genome-wide ChIP-Seq reveals a dramatic shift in the binding of the transcription factor erythroid Kruppel-like factor during erythrocyte differentiation. Blood 2011; 118:e139-e148.
-
(2011)
Blood
, vol.118
-
-
Pilon, A.M.1
Ajay, S.S.2
Kumar, S.A.3
-
26
-
-
84890129231
-
Dynamic analysis of gene expression and genome-wide transcription factor binding during lineage specification of multipotent progenitors
-
May G, Soneji S, Tipping AJ, et al. Dynamic analysis of gene expression and genome-wide transcription factor binding during lineage specification of multipotent progenitors. Cell Stem Cell 2013; 13:754-768.
-
(2013)
Cell Stem Cell
, vol.13
, pp. 754-768
-
-
May, G.1
Soneji, S.2
Tipping, A.J.3
-
27
-
-
33846707892
-
Sticky fingers: Zinc-fingers as protein-recognition motifs
-
Gamsjaeger R, Liew CK, Loughlin FE, et al. Sticky fingers: zinc-fingers as protein-recognition motifs. Trends Biochem Sci 2007; 32:63-70.
-
(2007)
Trends Biochem Sci
, vol.32
, pp. 63-70
-
-
Gamsjaeger, R.1
Liew, C.K.2
Loughlin, F.E.3
-
28
-
-
0027265437
-
Dynamics of GATA transcription factor expression during erythroid differentiation
-
Leonard M, Brice M, Engel JD, et al. Dynamics of GATA transcription factor expression during erythroid differentiation. Blood 1993; 82:1071-1079.
-
(1993)
Blood
, vol.82
, pp. 1071-1079
-
-
Leonard, M.1
Brice, M.2
Engel, J.D.3
-
29
-
-
0025977563
-
Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1
-
Pevny L, Simon MC, Robertson E, et al. Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1. Nature 1991; 349:257-260.
-
(1991)
Nature
, vol.349
, pp. 257-260
-
-
Pevny, L.1
Simon, M.C.2
Robertson, E.3
-
30
-
-
5444223724
-
GATA-2 plays two functionally distinct roles during the ontogeny of hematopoietic stem cells
-
Ling KW, Ottersbach K, van Hamburg JP, et al. GATA-2 plays two functionally distinct roles during the ontogeny of hematopoietic stem cells. J Exp Med 2004; 200:871-882.
-
(2004)
J Exp Med
, vol.200
, pp. 871-882
-
-
Ling, K.W.1
Ottersbach, K.2
Van Hamburg, J.P.3
-
31
-
-
84890808924
-
Gata2 cis-element is required for hematopoietic stem cell generation in the mammalian embryo
-
Gao X, Johnson KD, Chang Y-I, et al. Gata2 cis-element is required for hematopoietic stem cell generation in the mammalian embryo. J Exp Med 2013; 210:2833-2842.
-
(2013)
J Exp Med
, vol.210
, pp. 2833-2842
-
-
Gao, X.1
Johnson, K.D.2
Chang, Y.-I.3
-
32
-
-
84890847135
-
Gata2 is required for HSC generation and survival
-
de Pater E, Kaimakis P, Vink CS, et al. Gata2 is required for HSC generation and survival. J Exp Med 2013; 210:2843-2850.
-
(2013)
J Exp Med
, vol.210
, pp. 2843-2850
-
-
De Pater, E.1
Kaimakis, P.2
Vink, C.S.3
-
33
-
-
84867163662
-
Cis-element mutated in GATA2-dependent immunodeficiency governs hematopoiesis and vascular integrity
-
Johnson KD, Hsu AP, Ryu MJ, et al. Cis-element mutated in GATA2-dependent immunodeficiency governs hematopoiesis and vascular integrity. J Clin Invest 2012; 122:3692-3704.
-
(2012)
J Clin Invest
, vol.122
, pp. 3692-3704
-
-
Johnson, K.D.1
Hsu, A.P.2
Ryu, M.J.3
-
34
-
-
84867163397
-
Conditional Gata2 inactivation results in HSC loss and lymphatic mispatterning
-
Lim KC, Hosoya T, Brandt W, et al. Conditional Gata2 inactivation results in HSC loss and lymphatic mispatterning. J Clin Invest 2012; 122:3705-3717.
-
(2012)
J Clin Invest
, vol.122
, pp. 3705-3717
-
-
Lim, K.C.1
Hosoya, T.2
Brandt, W.3
-
35
-
-
38349178680
-
Differential GATA factor stabilities: Implications for chromatin occupancy by structurally similar transcription factors
-
Lurie LJ, Boyer ME, Grass JA, et al. Differential GATA factor stabilities: implications for chromatin occupancy by structurally similar transcription factors. Biochemistry 2008; 47:859-869.
-
(2008)
Biochemistry
, vol.47
, pp. 859-869
-
-
Lurie, L.J.1
Boyer, M.E.2
Grass, J.A.3
-
36
-
-
0032522474
-
Failure of megakaryopoiesis and arrested erythropoiesis in mice lacking the GATA-1 transcriptional cofactor FOG
-
Tsang AP, Fujiwara Y, Hom DB, et al. Failure of megakaryopoiesis and arrested erythropoiesis in mice lacking the GATA-1 transcriptional cofactor FOG. Genes Dev 1998; 12:1176-1188.
-
(1998)
Genes Dev
, vol.12
, pp. 1176-1188
-
-
Tsang, A.P.1
Fujiwara, Y.2
Hom, D.B.3
-
37
-
-
0033083804
-
Use of altered specificity mutants to probe a specific protein-protein interaction in differentiation: The GATA-1:FOG complex
-
Crispino JD, Lodish MB, MacKay JP, et al. Use of altered specificity mutants to probe a specific protein-protein interaction in differentiation: the GATA-1:FOG complex. Mol Cell 1999; 3:219-228.
-
(1999)
Mol Cell
, vol.3
, pp. 219-228
-
-
Crispino, J.D.1
Lodish, M.B.2
MacKay, J.P.3
-
38
-
-
77957783607
-
GATA switches as developmental drivers
-
Bresnick EH, Lee HY, Fujiwara T, et al. GATA switches as developmental drivers. J Biol Chem 2010; 285:31087-31093.
-
(2010)
J Biol Chem
, vol.285
, pp. 31087-31093
-
-
Bresnick, E.H.1
Lee, H.Y.2
Fujiwara, T.3
-
39
-
-
84863649033
-
Master regulatory GATA transcription factors: Mechanistic principles and emerging links to hematologic malignancies
-
Bresnick EH, Katsumura KR, Lee HY, et al. Master regulatory GATA transcription factors: mechanistic principles and emerging links to hematologic malignancies. Nucleic Acids Res 2012; 40:5819-5831.
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 5819-5831
-
-
Bresnick, E.H.1
Katsumura, K.R.2
Lee, H.Y.3
-
40
-
-
0041806587
-
GATA-1-dependent transcriptional repression of GATA-2 via disruption of positive autoregulation and domain-wide chromatin remodeling
-
Grass JA, Boyer ME, Pal S, et al. GATA-1-dependent transcriptional repression of GATA-2 via disruption of positive autoregulation and domain-wide chromatin remodeling. Proc Natl Acad Sci USA 2003; 100:8811-8816.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 8811-8816
-
-
Grass, J.A.1
Boyer, M.E.2
Pal, S.3
-
41
-
-
12544253500
-
Dynamic GATA factor interplay at a multicomponent regulatory region of the GATA-2 locus
-
Martowicz ML, Grass JA, Boyer ME, et al. Dynamic GATA factor interplay at a multicomponent regulatory region of the GATA-2 locus. J Biol Chem 2005; 280:1724-1732.
-
(2005)
J Biol Chem
, vol.280
, pp. 1724-1732
-
-
Martowicz, M.L.1
Grass, J.A.2
Boyer, M.E.3
-
42
-
-
33749166029
-
Distinct functions of dispersed GATA factor complexes at an endogenous gene locus
-
Grass JA, Jing H, Kim SI, et al. Distinct functions of dispersed GATA factor complexes at an endogenous gene locus. Mol Cell Biol 2006; 26:7056-7067.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 7056-7067
-
-
Grass, J.A.1
Jing, H.2
Kim, S.I.3
-
43
-
-
77957912884
-
A key commitment step in erythropoiesis is synchronized with the cell cycle clock through mutual inhibition between PU.1 and S-phase progression
-
Pop R, Shearstone JR, Shen Q, et al. A key commitment step in erythropoiesis is synchronized with the cell cycle clock through mutual inhibition between PU.1 and S-phase progression. PLoS Biol 2010; 8:e1000484.
-
(2010)
PLoS Biol
, vol.8
-
-
Pop, R.1
Shearstone, J.R.2
Shen, Q.3
-
44
-
-
84860339002
-
Chromatin occupancy analysis reveals genome-wide GATA factor switching during hematopoiesis
-
Dore LC, Chlon TM, Brown CD, et al. Chromatin occupancy analysis reveals genome-wide GATA factor switching during hematopoiesis. Blood 2012; 119:3724-3733.
-
(2012)
Blood
, vol.119
, pp. 3724-3733
-
-
Dore, L.C.1
Chlon, T.M.2
Brown, C.D.3
-
45
-
-
84883323024
-
Establishing a hematopoietic genetic network through locus-specific integration of chromatin regulators
-
DeVilbiss AW, Boyer ME, Bresnick EH. Establishing a hematopoietic genetic network through locus-specific integration of chromatin regulators. Proc Natl Acad Sci USA 2013; 110:E3398-E3407.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
-
-
Devilbiss, A.W.1
Boyer, M.E.2
Bresnick, E.H.3
-
46
-
-
77952303405
-
Differential coregulator requirements for function of the hematopoietic transcription factor GATA-1 at endogenous loci
-
Pope NJ, Bresnick EH. Differential coregulator requirements for function of the hematopoietic transcription factor GATA-1 at endogenous loci. Nucleic Acids Res 2010; 38:2190-2200.
-
(2010)
Nucleic Acids Res
, vol.38
, pp. 2190-2200
-
-
Pope, N.J.1
Bresnick, E.H.2
-
47
-
-
78650563327
-
Building multifunctionality into a complex containing master regulators of hematopoiesis
-
Fujiwara T, Lee HY, Sanalkumar R, et al. Building multifunctionality into a complex containing master regulators of hematopoiesis. Proc Natl Acad Sci USA 2010; 107:20429-20434.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 20429-20434
-
-
Fujiwara, T.1
Lee, H.Y.2
Sanalkumar, R.3
-
48
-
-
34250183131
-
Dissecting molecular steps in chromatin domain activation during hematopoietic differentiation
-
Kim SI, Bultman SJ, Jing H, et al. Dissecting molecular steps in chromatin domain activation during hematopoietic differentiation. Mol Cell Biol 2007; 27:4551-4565.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 4551-4565
-
-
Kim, S.I.1
Bultman, S.J.2
Jing, H.3
-
49
-
-
34250021087
-
Friend of GATA-1-independent transcriptional repression: A novel mode of GATA-1 function
-
Johnson KD, Boyer ME, Kang JA, et al. Friend of GATA-1-independent transcriptional repression: a novel mode of GATA-1 function. Blood 2007; 109:5230-5233.
-
(2007)
Blood
, vol.109
, pp. 5230-5233
-
-
Johnson, K.D.1
Boyer, M.E.2
Kang, J.A.3
-
50
-
-
0033577703
-
Transcriptional cofactors of the FOG family interact with GATA proteins by means of multiple zinc fingers
-
Fox AH, Liew C, Holmes M, et al. Transcriptional cofactors of the FOG family interact with GATA proteins by means of multiple zinc fingers. EMBO J 1999; 18:2812-2822.
-
(1999)
EMBO J
, vol.18
, pp. 2812-2822
-
-
Fox, A.H.1
Liew, C.2
Holmes, M.3
-
51
-
-
0025203886
-
Transcriptional activation and DNA binding by the erythroid factor GF-1/NF-E1/Eryf 1
-
Martin DI, Orkin SH. Transcriptional activation and DNA binding by the erythroid factor GF-1/NF-E1/Eryf 1. Genes Dev 1990; 4:1886-1898.
-
(1990)
Genes Dev
, vol.4
, pp. 1886-1898
-
-
Martin, D.I.1
Orkin, S.H.2
-
52
-
-
0345184762
-
An erythrocyte-specific DNA-binding factor recognizes a regulatory sequence common to all chicken globin genes
-
Evans T, Reitman M, Felsenfeld G. An erythrocyte-specific DNA-binding factor recognizes a regulatory sequence common to all chicken globin genes. Proc Natl Acad Sci USA 1988; 85:5976-5980.
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 5976-5980
-
-
Evans, T.1
Reitman, M.2
Felsenfeld, G.3
-
53
-
-
74949090052
-
NuRD mediates activating and repressive functions of GATA-1 and FOG-1 during blood development
-
Miccio A, Wang Y, Hong W, et al. NuRD mediates activating and repressive functions of GATA-1 and FOG-1 during blood development. EMBO J 2010; 29:442-456.
-
(2010)
EMBO J
, vol.29
, pp. 442-456
-
-
Miccio, A.1
Wang, Y.2
Hong, W.3
-
54
-
-
22744436722
-
FOG-1 recruits the NuRD repressor complex to mediate transcriptional repression by GATA-1
-
Hong W, Nakazawa M, Chen YY, et al. FOG-1 recruits the NuRD repressor complex to mediate transcriptional repression by GATA-1. EMBO J 2005; 24:2367-2378.
-
(2005)
EMBO J
, vol.24
, pp. 2367-2378
-
-
Hong, W.1
Nakazawa, M.2
Chen, Y.Y.3
-
55
-
-
0742288407
-
Coregulator-dependent facilitation of chromatin occupancy by GATA-1
-
Pal S, Cantor AB, Johnson KD, et al. Coregulator-dependent facilitation of chromatin occupancy by GATA-1. Proc Natl Acad Sci USA 2004; 101:980-985.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 980-985
-
-
Pal, S.1
Cantor, A.B.2
Johnson, K.D.3
-
56
-
-
0346374823
-
Context-dependent regulation of GATA-1 by friend of GATA-1
-
Letting DL, Chen YY, Rakowski C, et al. Context-dependent regulation of GATA-1 by friend of GATA-1. Proc Natl Acad Sci USA 2004; 101:476-481.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 476-481
-
-
Letting, D.L.1
Chen, Y.Y.2
Rakowski, C.3
-
57
-
-
0030999645
-
The LIM-only protein Lmo2 is a bridging molecule assembling an erythroid, DNA-binding complex which includes the TAL1, E47, GATA-1 and Ldb1/NLI proteins
-
Wadman IA, Osada H, Grutz GG, et al. The LIM-only protein Lmo2 is a bridging molecule assembling an erythroid, DNA-binding complex which includes the TAL1, E47, GATA-1 and Ldb1/NLI proteins. EMBO J 1997; 16:3145-3157.
-
(1997)
EMBO J
, vol.16
, pp. 3145-3157
-
-
Wadman, I.A.1
Osada, H.2
Grutz, G.G.3
-
58
-
-
64049118936
-
SCL and associated proteins distinguish active from repressive GATA transcription factor complexes
-
Tripic T, Deng W, Cheng Y, et al. SCL and associated proteins distinguish active from repressive GATA transcription factor complexes. Blood 2009; 113:2191-2201.
-
(2009)
Blood
, vol.113
, pp. 2191-2201
-
-
Tripic, T.1
Deng, W.2
Cheng, Y.3
-
59
-
-
55449130784
-
Molecular hallmarks of endogenous chromatin complexes containing master regulators of hematopoiesis
-
Wozniak RJ, Keles S, Lugus JJ, et al. Molecular hallmarks of endogenous chromatin complexes containing master regulators of hematopoiesis. Mol Cell Biol 2008; 28:6681-6694.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 6681-6694
-
-
Wozniak, R.J.1
Keles, S.2
Lugus, J.J.3
-
60
-
-
3543038232
-
Globin gene activation during haemopoiesis is driven by protein complexes nucleated by GATA-1 and GATA-2
-
Anguita E, Hughes J, Heyworth C, et al. Globin gene activation during haemopoiesis is driven by protein complexes nucleated by GATA-1 and GATA-2. EMBO J 2004; 23:2841-2852.
-
(2004)
EMBO J
, vol.23
, pp. 2841-2852
-
-
Anguita, E.1
Hughes, J.2
Heyworth, C.3
-
61
-
-
76149089221
-
The genome-wide dynamics of the binding of Ldb1 complexes during erythroid differentiation
-
Soler E, Andrieu-Soler C, de Boer E, et al. The genome-wide dynamics of the binding of Ldb1 complexes during erythroid differentiation.Genes Dev 2010; 24:277-289.
-
(2010)
Genes Dev
, vol.24
, pp. 277-289
-
-
Soler, E.1
Andrieu-Soler, C.2
De Boer, E.3
-
62
-
-
84880832596
-
Ldb1-nucleated transcription complexes function as primary mediators of global erythroid gene activation
-
Li L, Freudenberg J, Cui K, et al. Ldb1-nucleated transcription complexes function as primary mediators of global erythroid gene activation. Blood 2013; 121:4575-4585.
-
(2013)
Blood
, vol.121
, pp. 4575-4585
-
-
Li, L.1
Freudenberg, J.2
Cui, K.3
-
63
-
-
84891159436
-
Ldb1 complexes: The new master regulators of erythroid gene transcription
-
Love PE, Warzecha C, Li L. Ldb1 complexes: the new master regulators of erythroid gene transcription. Trends Genet 2014; 30:1-9.
-
(2014)
Trends Genet
, vol.30
, pp. 1-9
-
-
Love, P.E.1
Warzecha, C.2
Li, L.3
-
64
-
-
28444439242
-
A Brg1 mutation that uncouples ATPase activity from chromatin remodeling reveals an essential role for SWI/SNF-related complexes in beta-globin expression and erythroid development
-
Bultman SJ, Gebuhr TC, Magnuson T. A Brg1 mutation that uncouples ATPase activity from chromatin remodeling reveals an essential role for SWI/SNF-related complexes in beta-globin expression and erythroid development. Genes Dev 2005; 19:2849-2861.
-
(2005)
Genes Dev
, vol.19
, pp. 2849-2861
-
-
Bultman, S.J.1
Gebuhr, T.C.2
Magnuson, T.3
-
65
-
-
80053501181
-
Regulation of nucleosome landscape and transcription factor targeting at tissue-specific enhancers by BRG1
-
Hu G, Schones DE, Cui K, et al. Regulation of nucleosome landscape and transcription factor targeting at tissue-specific enhancers by BRG1. Genome Res 2011; 21:1650-1658.
-
(2011)
Genome Res
, vol.21
, pp. 1650-1658
-
-
Hu, G.1
Schones, D.E.2
Cui, K.3
-
66
-
-
84867736794
-
Combinatorial assembly of developmental stagespecific enhancers controls gene expression programs during human erythropoiesis
-
Xu J, Shao Z, Glass K, et al. Combinatorial assembly of developmental stagespecific enhancers controls gene expression programs during human erythropoiesis. Dev Cell 2012; 23:796-811.
-
(2012)
Dev Cell
, vol.23
, pp. 796-811
-
-
Xu, J.1
Shao, Z.2
Glass, K.3
-
67
-
-
80051995505
-
Genetic framework for GATA factor function in vascular biology
-
Linnemann AK, O'Geen H, Keles S, et al. Genetic framework for GATA factor function in vascular biology. Proc Natl Acad Sci USA 2011; 108:13641-13646.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 13641-13646
-
-
Linnemann, A.K.1
O'Geen, H.2
Keles, S.3
-
68
-
-
77957348625
-
Combinatorial transcriptional control in blood stem/progenitor cells: Genome-wide analysis of ten major transcriptional regulators
-
Wilson NK, Foster SD, Wang X, et al. Combinatorial transcriptional control in blood stem/progenitor cells: genome-wide analysis of ten major transcriptional regulators. Cell Stem Cell 2010; 7:532-544.
-
(2010)
Cell Stem Cell
, vol.7
, pp. 532-544
-
-
Wilson, N.K.1
Foster, S.D.2
Wang, X.3
-
69
-
-
0031024994
-
Erythroid-cell-specific properties of transcription factor GATA-1 revealed by phenotypic rescue of a gene-targeted cell line
-
Weiss MJ, Yu C, Orkin SH. Erythroid-cell-specific properties of transcription factor GATA-1 revealed by phenotypic rescue of a gene-targeted cell line. Mol Cell Biol 1997; 17:1642-1651.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 1642-1651
-
-
Weiss, M.J.1
Yu, C.2
Orkin, S.H.3
-
70
-
-
8644228649
-
Global regulation of erythroid gene expression by transcription factor GATA-1
-
Welch JJ, Watts JA, Vakoc CR, et al. Global regulation of erythroid gene expression by transcription factor GATA-1. Blood 2004; 104:3136-3147.
-
(2004)
Blood
, vol.104
, pp. 3136-3147
-
-
Welch, J.J.1
Watts, J.A.2
Vakoc, C.R.3
-
71
-
-
0036258216
-
Distinct domains of the GATA-1 cofactor FOG-1 differentially influence erythroid versus megakaryocytic maturation
-
Cantor AB, Katz SG, Orkin SH. Distinct domains of the GATA-1 cofactor FOG-1 differentially influence erythroid versus megakaryocytic maturation. Mol Cell Biol 2002; 22:4268-4279.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 4268-4279
-
-
Cantor, A.B.1
Katz, S.G.2
Orkin, S.H.3
-
72
-
-
0037195069
-
Hematopoietic-specific activators establish an overlapping pattern of histone acetylation and methylation within a mammalian chromatin domain
-
Kiekhaefer CM, Grass JA, Johnson KD, et al. Hematopoietic-specific activators establish an overlapping pattern of histone acetylation and methylation within a mammalian chromatin domain. Proc Natl Acad Sci USA 2002; 99:14309-14314.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 14309-14314
-
-
Kiekhaefer, C.M.1
Grass, J.A.2
Johnson, K.D.3
-
73
-
-
0037317298
-
Formation of a tissue-specific histone acetylation pattern by the hematopoietic transcription factor GATA-1
-
Letting DL, Rakowski C, Weiss MJ, et al. Formation of a tissue-specific histone acetylation pattern by the hematopoietic transcription factor GATA-1. Mol Cell Biol 2003; 23:1334-1340.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 1334-1340
-
-
Letting, D.L.1
Rakowski, C.2
Weiss, M.J.3
-
74
-
-
28044437502
-
Chromatin domain activation via GATA-1 utilization of a small subset of dispersed GATA motifs within a broad chromosomal region
-
Im H, Grass JA, Johnson KD, et al. Chromatin domain activation via GATA-1 utilization of a small subset of dispersed GATA motifs within a broad chromosomal region. Proc Natl Acad Sci USA 2005; 102:17065-17070.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 17065-17070
-
-
Im, H.1
Grass, J.A.2
Johnson, K.D.3
-
75
-
-
13244272059
-
Proximity among distant regulatory elements at the beta-globin locus requires GATA-1 and FOG-1
-
Vakoc CR, Letting DL, Gheldof N, et al. Proximity among distant regulatory elements at the beta-globin locus requires GATA-1 and FOG-1. Mol Cell 2005; 17:453-462.
-
(2005)
Mol Cell
, vol.17
, pp. 453-462
-
-
Vakoc, C.R.1
Letting, D.L.2
Gheldof, N.3
-
76
-
-
36749056884
-
A positive role for NLI/Ldb1 in long-range betaglobin locus control region function
-
Song SH, Hou C, Dean A. A positive role for NLI/Ldb1 in long-range betaglobin locus control region function. Mol Cell 2007; 28:810-822.
-
(2007)
Mol Cell
, vol.28
, pp. 810-822
-
-
Song, S.H.1
Hou, C.2
Dean, A.3
-
77
-
-
60549103722
-
BRG1 requirement for long-range interaction of a locus control region with a downstream promoter
-
Kim SI, Bultman SJ, Kiefer CM, et al. BRG1 requirement for long-range interaction of a locus control region with a downstream promoter. Proc Natl Acad Sci USA 2009; 106:2259-2264.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 2259-2264
-
-
Kim, S.I.1
Bultman, S.J.2
Kiefer, C.M.3
-
78
-
-
72149086961
-
Controlling hematopoiesis through sumoylation-dependent regulation of a GATA factor
-
Lee HY, Johnson KD, Fujiwara T, et al. Controlling hematopoiesis through sumoylation-dependent regulation of a GATA factor. Mol Cell 2009; 36:984-995.
-
(2009)
Mol Cell
, vol.36
, pp. 984-995
-
-
Lee, H.Y.1
Johnson, K.D.2
Fujiwara, T.3
-
79
-
-
79956304003
-
Relocalizing genetic loci into specific subnuclear neighborhoods
-
Lee HY, Johnson KD, Boyer ME, et al. Relocalizing genetic loci into specific subnuclear neighborhoods. J Biol Chem 2011; 286:18834-18844.
-
(2011)
J Biol Chem
, vol.286
, pp. 18834-18844
-
-
Lee, H.Y.1
Johnson, K.D.2
Boyer, M.E.3
-
80
-
-
33744779614
-
The locus control region is required for association of the murine beta-globin locus with engaged transcription factories during erythroid maturation
-
Ragoczy T, Bender MA, Telling A, et al. The locus control region is required for association of the murine beta-globin locus with engaged transcription factories during erythroid maturation. Genes Dev 2006; 20:1447-1457.
-
(2006)
Genes Dev
, vol.20
, pp. 1447-1457
-
-
Ragoczy, T.1
Bender, M.A.2
Telling, A.3
-
81
-
-
84885774880
-
Something silent this way forms: The functional organization of the repressive nuclear compartment
-
Politz JC, Scalzo D, Groudine M. Something silent this way forms: the functional organization of the repressive nuclear compartment. Annu Rev Cell Dev Biol 2013; 29:241-270.
-
(2013)
Annu Rev Cell Dev Biol
, vol.29
, pp. 241-270
-
-
Politz, J.C.1
Scalzo, D.2
Groudine, M.3
-
82
-
-
5444255213
-
The active spatial organization of the beta-globin locus requires the transcription factor EKLF
-
Drissen R, Palstra RJ, Gillemans N, et al. The active spatial organization of the beta-globin locus requires the transcription factor EKLF. Genes Dev 2004; 18:2485-2490.
-
(2004)
Genes Dev
, vol.18
, pp. 2485-2490
-
-
Drissen, R.1
Palstra, R.J.2
Gillemans, N.3
-
83
-
-
73349090560
-
Preferential associations between co-regulated genes reveal a transcriptional interactome in erythroid cells
-
Schoenfelder S, Sexton T, Chakalova L, et al. Preferential associations between co-regulated genes reveal a transcriptional interactome in erythroid cells. Nat Genet 2010; 42:53-61.
-
(2010)
Nat Genet
, vol.42
, pp. 53-61
-
-
Schoenfelder, S.1
Sexton, T.2
Chakalova, L.3
-
84
-
-
84865273512
-
Tissue-specific mitotic bookmarking by hematopoietic transcription factor GATA1
-
Kadauke S, Udugama MI, Pawlicki JM, et al. Tissue-specific mitotic bookmarking by hematopoietic transcription factor GATA1. Cell 2012; 150:725-737.
-
(2012)
Cell
, vol.150
, pp. 725-737
-
-
Kadauke, S.1
Udugama, M.I.2
Pawlicki, J.M.3
-
85
-
-
0030807246
-
An upstream, DNaseI hypersensitive region of the hematopoietic-expressed transcription factor GATA-1 gene confers developmental specificity in transgenic mice
-
McDevitt MA, Fujiwara Y, Shivdasani RA, et al. An upstream, DNaseI hypersensitive region of the hematopoietic-expressed transcription factor GATA-1 gene confers developmental specificity in transgenic mice. Proc Natl Acad Sci USA 1997; 94:7976-7981.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 7976-7981
-
-
McDevitt, M.A.1
Fujiwara, Y.2
Shivdasani, R.A.3
-
86
-
-
0030963918
-
A 'knockdown' mutation created by cis-element gene targeting reveals the dependence of erythroid cell maturation on the level of transcription factor GATA-1
-
McDevitt MA, Shivdasani RA, Fujiwara Y, et al. A 'knockdown' mutation created by cis-element gene targeting reveals the dependence of erythroid cell maturation on the level of transcription factor GATA-1. Proc Natl Acad Sci USA 1997; 94:6781-6785.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 6781-6785
-
-
McDevitt, M.A.1
Shivdasani, R.A.2
Fujiwara, Y.3
-
87
-
-
0025876999
-
Functional analysis and in vivo footprinting implicate the erythroid transcription factor GATA-1 as a positive regulator of its own promoter
-
Tsai SF, Strauss E, Orkin SH. Functional analysis and in vivo footprinting implicate the erythroid transcription factor GATA-1 as a positive regulator of its own promoter. Genes Dev 1991; 5:919-931.
-
(1991)
Genes Dev
, vol.5
, pp. 919-931
-
-
Tsai, S.F.1
Strauss, E.2
Orkin, S.H.3
-
88
-
-
0034945358
-
Hematopoietic regulatory domain of GATA-1 gene is positively regulated by GATA-1 protein in Zebrafish embryos
-
Kobayashi M, Nishikawa K, Yamamoto M. Hematopoietic regulatory domain of GATA-1 gene is positively regulated by GATA-1 protein in Zebrafish embryos. Development 2001; 128:2341-2350.
-
(2001)
Development
, vol.128
, pp. 2341-2350
-
-
Kobayashi, M.1
Nishikawa, K.2
Yamamoto, M.3
-
89
-
-
77951204547
-
The Hox cofactors Meis1 and Pbx act upstream of gata1 to regulate primitive hematopoiesis
-
Pillay LM, Forrester AM, Erickson T, et al. The Hox cofactors Meis1 and Pbx act upstream of gata1 to regulate primitive hematopoiesis. Dev Biol 2010; 340:306-317.
-
(2010)
Dev Biol
, vol.340
, pp. 306-317
-
-
Pillay, L.M.1
Forrester, A.M.2
Erickson, T.3
-
90
-
-
0035806994
-
Critical role of biklf in erythroid cell differentiation in zebrafish
-
Kawahara A, Dawid IB. Critical role of biklf in erythroid cell differentiation in zebrafish. Curr Biol 2001; 11:1353-1357.
-
(2001)
Curr Biol
, vol.11
, pp. 1353-1357
-
-
Kawahara, A.1
Dawid, I.B.2
-
91
-
-
33750357137
-
The transcription factor ZBP-89 controls generation of the hematopoietic lineage in zebrafish and mouse embryonic stem cells
-
Li X, Xiong JW, Shelley CS, et al. The transcription factor ZBP-89 controls generation of the hematopoietic lineage in zebrafish and mouse embryonic stem cells. Development 2006; 133:3641-3650.
-
(2006)
Development
, vol.133
, pp. 3641-3650
-
-
Li, X.1
Xiong, J.W.2
Shelley, C.S.3
-
92
-
-
0036333387
-
The BMP/BMPR/Smad pathway directs expression of the erythroid-specific EKLF and GATA1 transcription factors during embryoid body differentiation in serum-free media
-
Adelman CA, Chattopadhyay S, Bieker JJ. The BMP/BMPR/Smad pathway directs expression of the erythroid-specific EKLF and GATA1 transcription factors during embryoid body differentiation in serum-free media. Development 2002; 129:539-549.
-
(2002)
Development
, vol.129
, pp. 539-549
-
-
Adelman, C.A.1
Chattopadhyay, S.2
Bieker, J.J.3
-
93
-
-
84896649611
-
PIAS1 SUMO ligase regulates the self-renewal and differentiation of hematopoietic stem cells
-
Liu B, Yee KM, Tahk S, et al. PIAS1 SUMO ligase regulates the self-renewal and differentiation of hematopoietic stem cells. EMBO J 2014; 33:101-113.
-
(2014)
EMBO J
, vol.33
, pp. 101-113
-
-
Liu, B.1
Yee, K.M.2
Tahk, S.3
-
94
-
-
0037071383
-
Transcriptional regulation of erythropoiesis: An affair involving multiple partners
-
Cantor AB, Orkin SH. Transcriptional regulation of erythropoiesis: an affair involving multiple partners. Oncogene 2002; 21:3368-3376.
-
(2002)
Oncogene
, vol.21
, pp. 3368-3376
-
-
Cantor, A.B.1
Orkin, S.H.2
-
95
-
-
70349229824
-
Graded repression of PU.1/Sfpi1 gene transcription by GATA factors regulates hematopoietic cell fate
-
Chou ST, Khandros E, Bailey LC, et al. Graded repression of PU.1/Sfpi1 gene transcription by GATA factors regulates hematopoietic cell fate. Blood 2009; 114:983-994.
-
(2009)
Blood
, vol.114
, pp. 983-994
-
-
Chou, S.T.1
Khandros, E.2
Bailey, L.C.3
-
96
-
-
0028243483
-
Phosphorylation of the erythroid transcription factor GATA-1
-
Crossley M, Orkin SH. Phosphorylation of the erythroid transcription factor GATA-1. J Biol Chem 1994; 269:16589-16596.
-
(1994)
J Biol Chem
, vol.269
, pp. 16589-16596
-
-
Crossley, M.1
Orkin, S.H.2
-
97
-
-
31544481433
-
Erythropoietin stimulates phosphorylation and activation of GATA-1 via the PI3-kinase/AKT signaling pathway
-
Zhao W, Kitidis C, Fleming MD, et al. Erythropoietin stimulates phosphorylation and activation of GATA-1 via the PI3-kinase/AKT signaling pathway. Blood 2006; 107:907-915.
-
(2006)
Blood
, vol.107
, pp. 907-915
-
-
Zhao, W.1
Kitidis, C.2
Fleming, M.D.3
-
98
-
-
33845275146
-
Acetylation of GATA-1 is required for chromatin occupancy
-
Lamonica JM, Vakoc CR, Blobel GA. Acetylation of GATA-1 is required for chromatin occupancy. Blood 2006; 108:3736-3738.
-
(2006)
Blood
, vol.108
, pp. 3736-3738
-
-
Lamonica, J.M.1
Vakoc, C.R.2
Blobel, G.A.3
-
99
-
-
77956251063
-
Sumoylation regulates interaction of FOG1 with C-terminal-binding protein (CTBP)
-
Snow JW, Kim J, Currie CR, et al. Sumoylation regulates interaction of FOG1 with C-terminal-binding protein (CTBP). J Biol Chem 2010; 285:28064-28075.
-
(2010)
J Biol Chem
, vol.285
, pp. 28064-28075
-
-
Snow, J.W.1
Kim, J.2
Currie, C.R.3
-
100
-
-
0942266030
-
Functional overlap of GATA-1 and GATA-2 in primitive hematopoietic development
-
Fujiwara Y, Chang AN, Williams AM, et al. Functional overlap of GATA-1 and GATA-2 in primitive hematopoietic development. Blood 2004; 103:583-585.
-
(2004)
Blood
, vol.103
, pp. 583-585
-
-
Fujiwara, Y.1
Chang, A.N.2
Williams, A.M.3
-
101
-
-
0032584104
-
The T cell leukemia LIM protein Lmo2 is necessary for adult mouse hematopoiesis
-
Yamada Y, Warren AJ, Dobson C, et al. The T cell leukemia LIM protein Lmo2 is necessary for adult mouse hematopoiesis. Proc Natl Acad Sci USA 1998; 95:3890-3895.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 3890-3895
-
-
Yamada, Y.1
Warren, A.J.2
Dobson, C.3
-
102
-
-
78751625306
-
Nuclear adaptor Ldb1 regulates a transcriptional program essential for the maintenance of hematopoietic stem cells
-
Li L, Jothi R, Cui K, et al. Nuclear adaptor Ldb1 regulates a transcriptional program essential for the maintenance of hematopoietic stem cells. Nat Immunol 2011; 12:129-136.
-
(2011)
Nat Immunol
, vol.12
, pp. 129-136
-
-
Li, L.1
Jothi, R.2
Cui, K.3
-
103
-
-
36749094041
-
Gata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic development
-
Pimanda JE, Ottersbach K, Knezevic K, et al. Gata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic development. Proc Natl Acad Sci USA 2007; 104:17692-17697.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 17692-17697
-
-
Pimanda, J.E.1
Ottersbach, K.2
Knezevic, K.3
-
104
-
-
58949098459
-
Adult hematopoietic stem and progenitor cells require either Lyl1 or Scl for survival
-
Souroullas GP, Salmon JM, Sablitzky F, et al. Adult hematopoietic stem and progenitor cells require either Lyl1 or Scl for survival. Cell Stem Cell 2009; 4:180-186.
-
(2009)
Cell Stem Cell
, vol.4
, pp. 180-186
-
-
Souroullas, G.P.1
Salmon, J.M.2
Sablitzky, F.3
-
105
-
-
1542343945
-
Functional regulation of GATA-2 by acetylation
-
Hayakawa F, Towatari M, Ozawa Y, et al. Functional regulation of GATA-2 by acetylation. J Leukoc Biol 2004; 75:529-540.
-
(2004)
J Leukoc Biol
, vol.75
, pp. 529-540
-
-
Hayakawa, F.1
Towatari, M.2
Ozawa, Y.3
-
106
-
-
0036479110
-
Defects of the heart, eye, and megakaryocytes in peroxisome proliferator activator receptor-binding protein (PBP) null embryos implicate GATA family of transcription factors
-
Crawford SE, Qi C, Misra P, et al. Defects of the heart, eye, and megakaryocytes in peroxisome proliferator activator receptor-binding protein (PBP) null embryos implicate GATA family of transcription factors. J Biol Chem 2002; 277:3585-3592.
-
(2002)
J Biol Chem
, vol.277
, pp. 3585-3592
-
-
Crawford, S.E.1
Qi, C.2
Misra, P.3
-
107
-
-
0035496915
-
Histone deacetylase 3 associates with and represses the transcription factor GATA-2
-
Ozawa Y, Towatari M, Tsuzuki S, et al. Histone deacetylase 3 associates with and represses the transcription factor GATA-2. Blood 2001; 98:2116-2123.
-
(2001)
Blood
, vol.98
, pp. 2116-2123
-
-
Ozawa, Y.1
Towatari, M.2
Tsuzuki, S.3
-
108
-
-
34748874309
-
GATA-2 functions downstream of BMPs and CaM KIV in ectodermal cells during primitive hematopoiesis
-
Dalgin G, Goldman DC, Donley N, et al. GATA-2 functions downstream of BMPs and CaM KIV in ectodermal cells during primitive hematopoiesis. Dev Biol 2007; 310:454-469.
-
(2007)
Dev Biol
, vol.310
, pp. 454-469
-
-
Dalgin, G.1
Goldman, D.C.2
Donley, N.3
-
109
-
-
3142734414
-
Involvement of mitogen-activated protein kinase in the cytokine-regulated phosphorylation of transcription factor GATA-1
-
Towatari M, Ciro M, Ottolenghi S, et al. Involvement of mitogen-activated protein kinase in the cytokine-regulated phosphorylation of transcription factor GATA-1. Hematol J 2004; 5:262-272.
-
(2004)
Hematol J
, vol.5
, pp. 262-272
-
-
Towatari, M.1
Ciro, M.2
Ottolenghi, S.3
-
110
-
-
17644404111
-
Phosphorylation of GATA2 by Akt increases adipose tissue differentiation and reduces adipose tissue-related inflammation: A novel pathway linking obesity to atherosclerosis
-
Menghini R, Marchetti V, Cardellini M, et al. Phosphorylation of GATA2 by Akt increases adipose tissue differentiation and reduces adipose tissue-related inflammation: a novel pathway linking obesity to atherosclerosis. Circulation 2005; 111:1946-1953.
-
(2005)
Circulation
, vol.111
, pp. 1946-1953
-
-
Menghini, R.1
Marchetti, V.2
Cardellini, M.3
-
111
-
-
34548462072
-
Unique and independent roles for MLL in adult hematopoietic stem cells and progenitors
-
Jude CD, Climer L, Xu D, et al. Unique and independent roles for MLL in adult hematopoietic stem cells and progenitors. Cell Stem Cell 2007; 1:324-337.
-
(2007)
Cell Stem Cell
, vol.1
, pp. 324-337
-
-
Jude, C.D.1
Climer, L.2
Xu, D.3
-
112
-
-
33344469959
-
The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion
-
Kamminga LM, Bystrykh LV, de Boer A, et al. The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion. Blood 2006; 107:2170-2179.
-
(2006)
Blood
, vol.107
, pp. 2170-2179
-
-
Kamminga, L.M.1
Bystrykh, L.V.2
De Boer, A.3
-
113
-
-
78649458797
-
Early mammalian erythropoiesis requires the Dot1L methyltransferase
-
Feng Y, Yang Y, Ortega MM, et al. Early mammalian erythropoiesis requires the Dot1L methyltransferase. Blood 2010; 116:4483-4491.
-
(2010)
Blood
, vol.116
, pp. 4483-4491
-
-
Feng, Y.1
Yang, Y.2
Ortega, M.M.3
-
114
-
-
11144332565
-
Histone demethylation mediated by the nuclear amine oxidase homolog LSD1
-
Shi Y, Lan F, Matson C, et al. Histone demethylation mediated by the nuclear amine oxidase homolog LSD1. Cell 2004; 119:941-953.
-
(2004)
Cell
, vol.119
, pp. 941-953
-
-
Shi, Y.1
Lan, F.2
Matson, C.3
-
115
-
-
84865864630
-
Lysine-specific demethylase 1 restricts hematopoietic progenitor proliferation and is essential for terminal differentiation
-
Sprussel A, Schulte JH, Weber S, et al. Lysine-specific demethylase 1 restricts hematopoietic progenitor proliferation and is essential for terminal differentiation. Leukemia 2012; 26:2039-2051.
-
(2012)
Leukemia
, vol.26
, pp. 2039-2051
-
-
Sprussel, A.1
Schulte, J.H.2
Weber, S.3
-
116
-
-
84879308118
-
Histone demethylase Lsd1 represses hematopoietic stem and progenitor cell signatures during blood cell maturation
-
Kerenyi MA, Shao Z, Hsu YJ, et al. Histone demethylase Lsd1 represses hematopoietic stem and progenitor cell signatures during blood cell maturation. Elife 2013; 2:e00633.
-
(2013)
Elife
, vol.2
-
-
Kerenyi, M.A.1
Shao, Z.2
Hsu, Y.J.3
-
117
-
-
81055139701
-
Global DNA demethylation during mouse erythropoiesis in vivo
-
Shearstone JR, Pop R, Bock C, et al. Global DNA demethylation during mouse erythropoiesis in vivo. Science 2011; 334:799-802.
-
(2011)
Science
, vol.334
, pp. 799-802
-
-
Shearstone, J.R.1
Pop, R.2
Bock, C.3
-
118
-
-
80054832679
-
Gene induction and repression during terminal erythropoiesis are mediated by distinct epigenetic changes
-
Wong P, Hattangadi SM, Cheng AW, et al. Gene induction and repression during terminal erythropoiesis are mediated by distinct epigenetic changes. Blood 2011; 118:e128-e138.
-
(2011)
Blood
, vol.118
-
-
Wong, P.1
Hattangadi, S.M.2
Cheng, A.W.3
-
119
-
-
84884829249
-
Mapping human epigenomes
-
Rivera CM, Ren B. Mapping human epigenomes. Cell 2013; 155:39-55.
-
(2013)
Cell
, vol.155
, pp. 39-55
-
-
Rivera, C.M.1
Ren, B.2
-
120
-
-
60149091656
-
ChIP-seq accurately predicts tissue-specific activity of enhancers
-
Visel A, Blow MJ, Li Z, et al. ChIP-seq accurately predicts tissue-specific activity of enhancers. Nature 2009; 457:854-858.
-
(2009)
Nature
, vol.457
, pp. 854-858
-
-
Visel, A.1
Blow, M.J.2
Li, Z.3
-
121
-
-
84882766972
-
Developmental fate and cellular maturity encoded in human regulatory DNA landscapes
-
Stergachis AB, Neph S, Reynolds A, et al. Developmental fate and cellular maturity encoded in human regulatory DNA landscapes. Cell 2013; 154:888-903.
-
(2013)
Cell
, vol.154
, pp. 888-903
-
-
Stergachis, A.B.1
Neph, S.2
Reynolds, A.3
-
122
-
-
84861733509
-
Using formaldehyde-assisted isolation of regulatory elements (FAIRE) to isolate active regulatory DNA
-
Simon JM, Giresi PG, Davis IJ, et al. Using formaldehyde-assisted isolation of regulatory elements (FAIRE) to isolate active regulatory DNA. Nat Protoc 2012; 7:256-267.
-
(2012)
Nat Protoc
, vol.7
, pp. 256-267
-
-
Simon, J.M.1
Giresi, P.G.2
Davis, I.J.3
-
123
-
-
0023663887
-
Position-independent high-level expression of the human b-globin gene in trangsenic mice
-
Grosveld F, van Assendelft GB, Greaves DR, et al. Position-independent high-level expression of the human b-globin gene in trangsenic mice. Cell 1987; 51:975-985.
-
(1987)
Cell
, vol.51
, pp. 975-985
-
-
Grosveld, F.1
Van Assendelft, G.B.2
Greaves, D.R.3
-
124
-
-
0023550898
-
Evidence for a locus activation region: The formation of developmentally stable hypersensitive sites in globin-expressing hybrids
-
Forrester WC, Takegawa S, Papayannopoulou T, et al. Evidence for a locus activation region: the formation of developmentally stable hypersensitive sites in globin-expressing hybrids. Nucleic Acids Res 1987; 15:10159-10177.
-
(1987)
Nucleic Acids Res
, vol.15
, pp. 10159-10177
-
-
Forrester, W.C.1
Takegawa, S.2
Papayannopoulou, T.3
-
125
-
-
0033861846
-
B-globin gene switching and DNaseI sensitivity of the endogenous b-globin locus in mice do not require the locus control region
-
Bender MA, Bulger M, Close J, et al. B-globin gene switching and DNaseI sensitivity of the endogenous b-globin locus in mice do not require the locus control region. Mol Cell 2000; 5:387-393.
-
(2000)
Mol Cell
, vol.5
, pp. 387-393
-
-
Bender, M.A.1
Bulger, M.2
Close, J.3
-
126
-
-
0035496898
-
Targeted deletion of 5'HS1 and 5'HS4 of the beta-globin locus control region reveals additive activity of the DNaseI hypersensitive sites
-
Bender MA, Roach JN, Halow J, et al. Targeted deletion of 5'HS1 and 5'HS4 of the beta-globin locus control region reveals additive activity of the DNaseI hypersensitive sites. Blood 2001; 98:2022-2027.
-
(2001)
Blood
, vol.98
, pp. 2022-2027
-
-
Bender, M.A.1
Roach, J.N.2
Halow, J.3
-
127
-
-
78049432269
-
A single cis element maintains repression of the key developmental regulator Gata2
-
Snow JW, Trowbridge JJ, Fujiwara T, et al. A single cis element maintains repression of the key developmental regulator Gata2. PLoS Genet 2010; 6:e1001103.
-
(2010)
PLoS Genet
, vol.6
-
-
Snow, J.W.1
Trowbridge, J.J.2
Fujiwara, T.3
-
128
-
-
79955948338
-
Context-dependent function of 'GATA switch' sites in vivo
-
Snow JW, Trowbridge JJ, Johnson KD, et al. Context-dependent function of 'GATA switch' sites in vivo. Blood 2011; 117:4769-4772.
-
(2011)
Blood
, vol.117
, pp. 4769-4772
-
-
Snow, J.W.1
Trowbridge, J.J.2
Johnson, K.D.3
-
129
-
-
84875157258
-
A library of TAL effector nucleases spanning the human genome
-
Kim Y, Kweon J, Kim A, et al. A library of TAL effector nucleases spanning the human genome. Nat Biotechnol 2013; 31:251-258.
-
(2013)
Nat Biotechnol
, vol.31
, pp. 251-258
-
-
Kim, Y.1
Kweon, J.2
Kim, A.3
-
130
-
-
84874624936
-
Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease
-
Cho SW, Kim S, Kim JM, et al. Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease. Nat Biotechnol 2013; 31:230-232.
-
(2013)
Nat Biotechnol
, vol.31
, pp. 230-232
-
-
Cho, S.W.1
Kim, S.2
Kim, J.M.3
-
131
-
-
57849083996
-
Human fetal hemoglobin expression is regulated by the developmental stage-specific repressor BCL11A
-
Sankaran VG, Menne TF, Xu J, et al. Human fetal hemoglobin expression is regulated by the developmental stage-specific repressor BCL11A. Science 2008; 322:1839-1842.
-
(2008)
Science
, vol.322
, pp. 1839-1842
-
-
Sankaran, V.G.1
Menne, T.F.2
Xu, J.3
-
132
-
-
84885620722
-
An erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level
-
Bauer DE, Kamran SC, Lessard S, et al. An erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level. Science 2013; 342:253-257.
-
(2013)
Science
, vol.342
, pp. 253-257
-
-
Bauer, D.E.1
Kamran, S.C.2
Lessard, S.3
-
133
-
-
33744475085
-
A regulatory SNP causes a human genetic disease by creating a new transcriptional promoter
-
De Gobbi M, Viprakasit V, Hughes JR, et al. A regulatory SNP causes a human genetic disease by creating a new transcriptional promoter. Science 2006; 312:1215-1217.
-
(2006)
Science
, vol.312
, pp. 1215-1217
-
-
De Gobbi, M.1
Viprakasit, V.2
Hughes, J.R.3
-
134
-
-
84896689530
-
Identification of the novel erythroid specific enhancer for ALAS2 gene and its loss of function mutation associated with congenital sideroblastic anemia
-
Kaneko K, Furuyama K, Fujiwara T, et al. Identification of the novel erythroid specific enhancer for ALAS2 gene and its loss of function mutation associated with congenital sideroblastic anemia. Hematologica 2014; 99:252-261.
-
(2014)
Hematologica
, vol.99
, pp. 252-261
-
-
Kaneko, K.1
Furuyama, K.2
Fujiwara, T.3
-
135
-
-
79961074298
-
Mutations in GATA2 are associated with the autosomal dominant and sporadic monocytopenia and mycobacterial infection (MonoMAC) syndrome
-
Hsu AP, Sampaio EP, Khan J, et al. Mutations in GATA2 are associated with the autosomal dominant and sporadic monocytopenia and mycobacterial infection (MonoMAC) syndrome. Blood 2011; 118:2653-2655.
-
(2011)
Blood
, vol.118
, pp. 2653-2655
-
-
Hsu, A.P.1
Sampaio, E.P.2
Khan, J.3
-
136
-
-
80053385569
-
Mutations in GATA2 cause primary lymphedema associated with a predisposition to acute myeloid leukemia (Emberger syndrome)
-
Ostergaard P, Simpson MA, Connell FC, et al. Mutations in GATA2 cause primary lymphedema associated with a predisposition to acute myeloid leukemia (Emberger syndrome). Nat Genet 2011; 43:929-931.
-
(2011)
Nat Genet
, vol.43
, pp. 929-931
-
-
Ostergaard, P.1
Simpson, M.A.2
Connell, F.C.3
-
137
-
-
80053383273
-
Heritable GATA2 mutations associated with familial myelodysplastic syndrome, acute myeloid leukemia
-
Hahn CH, Chong C-E, Carmichael CL, et al. Heritable GATA2 mutations associated with familial myelodysplastic syndrome, acute myeloid leukemia. Nat Genet 2011; 43:1012-1017.
-
(2011)
Nat Genet
, vol.43
, pp. 1012-1017
-
-
Hahn, C.H.1
Chong, C.-E.2
Carmichael, C.L.3
-
138
-
-
80052089944
-
Exome sequencing identifies GATA-2 mutation as the cause of dendritic cell, monocyte, B and NK lymphoid deficiency
-
Dickinson RE, Griffin H, Bigley V, et al. Exome sequencing identifies GATA-2 mutation as the cause of dendritic cell, monocyte, B and NK lymphoid deficiency. Blood 2011; 118:2656-2658.
-
(2011)
Blood
, vol.118
, pp. 2656-2658
-
-
Dickinson, R.E.1
Griffin, H.2
Bigley, V.3
-
139
-
-
84880449489
-
GATA2 haploinsufficiency caused by mutations in a conserved intronic element leads to MonoMAC syndrome
-
Hsu AP, Johnson KD, Falcone EL, et al. GATA2 haploinsufficiency caused by mutations in a conserved intronic element leads to MonoMAC syndrome. Blood 2013; 121:3830-3837.
-
(2013)
Blood
, vol.121
, pp. 3830-3837
-
-
Hsu, A.P.1
Johnson, K.D.2
Falcone, E.L.3
-
140
-
-
84886709919
-
Variation at 3p24.1 and 6q23.3 influences the risk of Hodgkin's lymphoma
-
Frampton M, da Silva Filho MI, Broderick P, et al. Variation at 3p24.1 and 6q23.3 influences the risk of Hodgkin's lymphoma. Nat Commun 2013; 4:2549.
-
(2013)
Nat Commun
, vol.4
, pp. 2549
-
-
Frampton, M.1
Da Silva Filho, M.I.2
Broderick, P.3
-
141
-
-
70350646902
-
Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium
-
Ganesh SK, Zakai NA, van Rooij FJ, et al. Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. Nat Genet 2009; 41:1191-1198.
-
(2009)
Nat Genet
, vol.41
, pp. 1191-1198
-
-
Ganesh, S.K.1
Zakai, N.A.2
Van Rooij, F.J.3
|