GATA-2 functions downstream of BMPs and CaM KIV in ectodermal cells during primitive hematopoiesis

Developmental Biology

Volumn 310, Issue 2, 2007, Pages 454-469

  Dalgin, Gokhan ^a   Goldman, Devorah C ^a   Donley, Nathan ^a   Ahmed, Riffat ^a   Eide, Christopher A ^a   Christian, Jan L ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Acetylation; Bone morphogenetic protein; CaM KIV; CBP; Erythropoiesis; GATA 2; Hematopoiesis; Xenopus laevis

Indexed keywords

BONE MORPHOGENETIC PROTEIN; CALMODULIN DEPENDENT PROTEIN KINASE IV; PROTEIN KINASE; TRANSCRIPTION FACTOR GATA 2; UNCLASSIFIED DRUG;

ACETYLATION; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ECTODERM; EMBRYO; ERYTHROPOIESIS; GENE FUNCTION; GENE LOSS; HEMATOPOIESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; XENOPUS LAEVIS;

XENOPUS LAEVIS;

EID: 34748874309     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ydbio.2007.08.012     Document Type: Article

References (79)

1. Afouda B.A., Ciau-Uitz A., and Patient R. GATA4, 5 and 6 mediate TGFbeta maintenance of endodermal gene expression in Xenopus embryos. Development 132 (2005) 763-774
2. Ahn S., Ginty D.D., and Linden D.J. A late phase of cerebellar long-term depression requires activation of CaMKIV and CREB. Neuron 23 (1999) 559-568
3. Baron M.H. Embryonic origins of mammalian hematopoiesis. Exp. Hematol. 31 (2003) 1160-1169
4. Belaoussoff M., Farrington S.M., and Baron M.H. Hematopoietic induction and respecification of A-P identity by visceral endoderm signaling in the mouse embryo. Development 125 (1998) 5009-5018
5. Blobel G.A., Nakajima T., Eckner R., Montminy M., and Orkin S.H. CREB-binding protein cooperates with transcription factor GATA-1 and is required for erythroid differentiation. Proc. Natl. Acad. Sci. U. S. A. 95 (1998) 2061-2066
6. Brown III C.O., Chi X., Garcia-Gras E., Shirai M., Feng X.H., and Schwartz R.J. The cardiac determination factor, Nkx2.5, is activated by mutual cofactors GATA-4 and Smad1/4 via a novel upstream enhancer. J. Biol. Chem. 279 (2004) 10659-10669
7. Cardinaux J.R., Notis J.C., Zhang Q., Vo N., Craig J.C., Fass D.M., Brennan R.G., and Goodman R.H. Recruitment of CREB binding protein is sufficient for CREB-mediated gene activation. Mol. Cell. Biol. 20 (2000) 1546-1552
8. Chakravarti D., LaMorte V.J., Nelson M.C., Nakajima T., Schulman I.G., Juguilon H., Montminy M., and Evans R.M. Role of CBP/P300 in nuclear receptor signalling. Nature 383 (1996) 99-103
9. Christian J.L., and Moon R.T. Interactions between Xwnt-8 and Spemann organizer signaling pathways generate dorsoventral pattern in the embryonic mesoderm of Xenopus. Genes Dev. 7 (1993) 13-28
10. Ciau-Uitz A., Walmsley M., and Patient R. Distinct origins of adult and embryonic blood in Xenopus. Cell 102 (2000) 787-796
11. Cumano A., Dieterlen-Lievre F., and Godin I. Lymphoid potential, probed before circulation in mouse, is restricted to caudal intraembryonic splanchnopleura. Cell 86 (1996) 907-916
12. Davidson A.J., and Zon L.I. Turning mesoderm into blood: the formation of hematopoietic stem cells during embryogenesis. Curr. Top. Dev. Biol. 50 (2000) 45-60
13. de la Calle-Mustienes E., Lu Z., Cortes M., Andersen B., Modolell J., and Gomez-Skarmeta J.L. Xenopus Xlmo4 is a GATA cofactor during ventral mesoderm formation and regulates Ldb1 availability at the dorsal mesoderm and the neural plate. Dev. Biol. 264 (2003) 564-581
14. de Sousa Lopes S.M., Roelen B.A., Monteiro R.M., Emmens R., Lin H.Y., Li E., Lawson K.A., and Mummery C.L. BMP signaling mediated by ALK2 in the visceral endoderm is necessary for the generation of primordial germ cells in the mouse embryo. Genes Dev. 18 (2004) 1838-1849
15. Friedle H., and Knochel W. Cooperative interaction of Xvent-2 and GATA-2 in the activation of the ventral homeobox gene Xvent-1B. J. Biol. Chem. 277 (2002) 23872-23881
16. Fujiwara Y., Chang A.N., Williams A.M., and Orkin S.H. Functional overlap of GATA-1 and GATA-2 in primitive hematopoietic development. Blood 103 (2004) 583-585
17. Galloway J.L., and Zon L.I. Ontogeny of hematopoiesis: examining the emergence of hematopoietic cells in the vertebrate embryo. Curr. Top. Dev. Biol. 53 (2003) 139-158
18. Godin I.E., Garcia-Porrero J.A., Coutinho A., Dieterlen-Lievre F., and Marcos M.A. Para-aortic splanchnopleura from early mouse embryos contains B1a cell progenitors. Nature 364 (1993) 67-70
19. Goldman D.C., Berg L.K., Heinrich M.C., and Christian J.L. Ectodermally derived steel/stem cell factor functions non-cell autonomously during primitive erythropoiesis in Xenopus. Blood 107 (2006) 3114-3121
20. Gu Z., Reynolds E.M., Song J., Lei H., Feijen A., Yu L., He W., MacLaughlin D.T., van den Eijnden-van Raaij J., Donahoe P.K., and Li E. The type I serine/threonine kinase receptor ActRIA (ALK2) is required for gastrulation of the mouse embryo. Development 126 (1999) 2551-2561
21. Gupta S., Zhu H., Zon L.I., and Evans T. BMP signaling restricts hemato-vascular development from lateral mesoderm during somitogenesis. Development 133 (2006) 2177-2187
22. Hayakawa F., Towatari M., Ozawa Y., Tomita A., Privalsky M.L., and Saito H. Functional regulation of GATA-2 by acetylation. J. Leukoc. Biol. 75 (2004) 529-540
23. Hogan B.M., Layton J.E., Pyati U.J., Nutt S.L., Hayman J.W., Varma S., Heath J.K., Kimelman D., and Lieschke G.J. Specification of the primitive myeloid precursor pool requires signaling through Alk8 in zebrafish. Curr. Biol. 16 (2006) 506-511
24. Horton R.M., Cai Z.L., Ho S.N., and Pease L.R. Gene splicing by overlap extension: tailor-made genes using the polymerase chain reaction. BioTechniques 8 (1990) 528-535
25. Huo X., and Zhang J. Important roles of reversible acetylation in the function of hematopoietic transcription factors. J. Cell. Mol. Med. 9 (2005) 103-112
26. Kamei Y., Xu L., Heinzel T., Torchia J., Kurokawa R., Gloss B., Lin S.C., Heyman R.A., Rose D.W., Glass C.K., and Rosenfeld M.G. A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors. Cell 85 (1996) 403-414
27. Kato Y., Shi Y., and He X. Neuralization of the Xenopus embryo by inhibition of p300/CREB-binding protein function. J. Neurosci. 19 (1999) 9364-9373
28. Kau C.L., and Turpen J.B. Dual contribution of embryonic ventral blood island and dorsal lateral plate mesoderm during ontogeny of hemopoietic cells in Xenopus laevis. J. Immunol. 131 (1983) 2262-2266
29. Kelley C., Yee K., Harland R., and Zon L.I. Ventral expression of GATA-1 and GATA-2 in the Xenopus embryo defines induction of hematopoietic mesoderm. Dev. Biol. 165 (1994) 193-205
30. Kikkawa M., Yamazaki M., Izutsu Y., and Maeno M. Two-step induction of primitive erythrocytes in Xenopus laevis embryos: signals from the vegetal endoderm and the overlying ectoderm. Int. J. Dev. Biol. 45 (2001) 387-396
31. Kishimoto Y., Lee K.H., Zon L., Hammerschmidt M., and Schulte-Merker S. The molecular nature of zebrafish swirl: BMP2 function is essential during early dorsoventral patterning. Development 124 (1997) 4457-4466
32. Kitsos C.M., Sankar U., Illario M., Colomer-Font J., Duncan A.W., Ribar T.J., Reya T., and Means A.R. Calmodulin-dependent Protein Kinase IV regulates hematopoietic stem cell maintenance. J. Biol. Chem. 280 (2005) 33101-33108
33. Kumano G., Belluzzi L., and Smith W.C. Spatial and temporal properties of ventral blood island induction in Xenopus laevis. Development 126 (1999) 5327-5337
34. Lane M.C., and Sheets M.D. Primitive and definitive blood share a common origin in Xenopus: a comparison of lineage techniques used to construct fate maps. Dev. Biol. 248 (2002) 52-67
35. Lane M.C., and Smith W.C. The origins of primitive blood in Xenopus: implications for axial patterning. Development 126 (1999) 423-434
36. Lugas J.J., Chung Y.S., Mills J.S., Kim S.-I., Grass J.A., Kyba M., Doherty J.M., Bresnick E.H., and Choi K. GATA2 functions at multiple steps in hemangioblast development and differentiation. Development 134 (2007) 393-405
37. Maeno M. Regulatory signals and tissue interactions in the early hematopoietic cell differentiation in Xenopus laevis embryo. Zool. Sci. 20 (2003) 939-946
38. Maeno M.O.R., and Kung H.-f. Positive and negative regulation of the differentiation of ventral mesoderm for erythrocytes in Xenopus laevis. Dev. Growth Differ. 34 (1992) 567-577
39. Maeno M., Tochinai S., and Katagiri C. Differential participation of ventral and dorsolateral mesoderms in the hemopoiesis of Xenopus, as revealed in diploid-triploid or interspecific chimeras. Dev. Biol. 110 (1985) 503-508
40. Maeno M., Ong R.C., Suzuki A., Ueno N., and Kung H.F. A truncated bone morphogenetic protein 4 receptor alters the fate of ventral mesoderm to dorsal mesoderm: roles of animal pole tissue in the development of ventral mesoderm. Proc. Natl. Acad. Sci. U. S. A. 91 (1994) 10260-10264
41. Maeno M., Ong R.C., Xue Y., Nishimatsu S., Ueno N., and Kung H.F. Regulation of primary erythropoiesis in the ventral mesoderm of Xenopus gastrula embryo: evidence for the expression of a stimulatory factor(s) in animal pole tissue. Dev. Biol. 161 (1994) 522-529
42. Maeno M., Mead P.E., Kelley C., Xu R.H., Kung H.F., Suzuki A., Ueno N., and Zon L.I. The role of BMP-4 and GATA-2 in the induction and differentiation of hematopoietic mesoderm in Xenopus laevis. Blood 88 (1996) 1965-1972
43. Massague J., and Wotton D. Transcriptional control by the TGF-beta/Smad signaling system. EMBO J. 19 (2000) 1745-1754
44. Mead P.E., Kelley C.M., Hahn P.S., Piedad O., and Zon L.I. SCL specifies hematopoietic mesoderm in Xenopus embryos. Development 125 (1998) 2611-2620
45. Medvinsky A., and Dzierzak E. Definitive hematopoiesis is autonomously initiated by the AGM region. Cell 86 (1996) 897-906
46. Medvinsky A.L., Samoylina N.L., Muller A.M., and Dzierzak E.A. An early pre-liver intraembryonic source of CFU-S in the developing mouse. Nature 364 (1993) 64-67
47. Menghini R., Marchetti V., Cardellini M., Hribal M.L., Mauriello A., Lauro D., Sbraccia P., Lauro R., and Federici M. Phosphorylation of GATA2 by Akt increases adipose tissue differentiation and reduces adipose tissue-related inflammation: a novel pathway linking obesity to atherosclerosis. Circulation 111 (2005) 1946-1953
48. Mills K.R., Kruep D., and Saha M.S. Elucidating the origins of the vascular system: a fate map of the vascular endothelial and red blood cell lineages in Xenopus laevis. Dev. Biol. 209 (1999) 352-368
49. Minegishi N., Ohta J., Yamagiwa H., Suzuki N., Kawauchi S., Zhou Y., Takahashi S., Hayashi N., Engel J.D., and Yamamoto M. The mouse GATA-2 gene is expressed in the para-aortic splanchnopleura and aorta-gonads and mesonephros region. Blood 93 (1999) 4196-4207
50. Molkentin J.D. The zinc finger-containing transcription factors GATA-4, -5, and -6. Ubiquitously expressed regulators of tissue-specific gene expression. J. Biol. Chem. 275 (2000) 38949-38952
51. Moon R., and Christian J.L. Microinjection and expression of synthetic mRNAs in Xenopus embryos. Technique 1 (1989) 76-89
52. Mullins M.C., Hammerschmidt M., Kane D.A., Odenthal J., Brand M., van Eeden F.J., Furutani-Seiki M., Granato M., Haffter P., Heisenberg C.P., Jiang Y.J., Kelsh R.N., and Nusslein-Volhard C. Genes establishing dorsoventral pattern formation in the zebrafish embryo: the ventral specifying genes. Development 123 (1996) 81-93
53. Nakayama T., Snyder M.A., Grewal S.S., Tsuneizumi K., Tabata T., and Christian J.L. Xenopus Smad8 acts downstream of BMP-4 to modulate its activity during vertebrate embryonic patterning. Development 125 (1998) 857-867
54. Narita N., Bielinska M., and Wilson D.B. Wild-type endoderm abrogates the ventral developmental defects associated with GATA-4 deficiency in the mouse. Dev. Biol. 189 (1997) 270-274
55. Nguyen V.H., Schmid B., Trout J., Connors S.A., Ekker M., and Mullins M.C. Ventral and lateral regions of the zebrafish gastrula, including the neural crest progenitors, are established by a bmp2b/swirl pathway of genes. Dev. Biol. 199 (1998) 93-110
56. Nieto M.A. Reorganizing the organizer 75 years on. Cell 98 (1999) 417-425
57. Nieuwkoop P.D., and Faber J. Normal Table of Xenopus laevis (1967), Amsterdam, North Holland Publishing Co, Amsterdam
58. Nishinakamura R., Matsumoto Y., Matsuda T., Ariizumi T., Heike T., Asashima M., and Yokota T. Activation of Stat3 by cytokine receptor gp130 ventralizes Xenopus embryos independent of BMP-4. Dev. Biol. 216 (1999) 481-490
59. Peng H.B. Xenopus laevis: practical uses in cell and molecular biology. Solutions and protocols. Methods Cell Biol. 36 (1991) 657-662
60. Peterkin T., Gibson A., and Patient R. GATA-6 maintains BMP-4 and Nkx2 expression during cardiomyocyte precursor maturation. EMBO J. 22 (2003) 4260-4273
61. Peterkin T., Gibson A., Loose M., and Patient R. The roles of GATA-4, -5 and -6 in vertebrate heart development. Semin. Cell Dev. Biol. 16 (2005) 83-94
62. Pyati U.J., Webb A.E., and Kimelman D. Transgenic zebrafish reveal stage-specific roles for Bmp signaling in ventral and posterior mesoderm development. Development 132 (2005) 2333-2343
63. Rhodes J., Hagen A., Hsu K., Deng M., Liu T.X., Look A.T., and Kanki J.P. Interplay of pu.1 and gata1 determines myelo-erythroid progenitor cell fate in zebrafish. Dev. Cell 8 (2005) 97-108
64. Rooke H.M., and Orkin S.H. Phosphorylation of Gata1 at serine residues 72, 142, and 310 is not essential for hematopoiesis in vivo. Blood 107 (2006) 3527-3530
65. Scarlett G.P., Elgar S.J., Cary P.D., Noble A.M., Orford R.L., Kneale G.G., and Guille M.J. Intact RNA-binding domains are necessary for structure-specific DNA binding and transcription control by CBTF122 during Xenopus development. J. Biol. Chem. 279 (2004) 52447-52455
66. Schmid B., Furthauer M., Connors S.A., Trout J., Thisse B., Thisse C., and Mullins M.C. Equivalent genetic roles for bmp7/snailhouse and bmp2b/swirl in dorsoventral pattern formation. Development 127 (2000) 957-967
67. Smith S.J., Kotecha S., Towers N., Latinkic B.V., and Mohun T.J. XPOX2-peroxidase expression and the XLURP-1 promoter reveal the site of embryonic myeloid cell development in Xenopus. Mech. Dev. 117 (2002) 173-186
68. Soderling T.R. The Ca-calmodulin-dependent protein kinase cascade. Trends Biochem. Sci. 24 (1999) 232-236
69. Sykes T.G., Rodaway A.R., Walmsley M.E., and Patient R.K. Suppression of GATA factor activity causes axis duplication in Xenopus. Development 125 (1998) 4595-4605
70. Takahashi T., Suwabe N., Dai P., Yamamoto M., Ishii S., and Nakano T. Inhibitory interaction of c-Myb and GATA-1 via transcriptional co-activator CBP. Oncogene 19 (2000) 134-140
71. Tsai F.Y., Keller G., Kuo F.C., Weiss M., Chen J., Rosenblatt M., Alt F.W., and Orkin S.H. An early haematopoietic defect in mice lacking the transcription factor GATA-2. Nature 371 (1994) 221-226
72. Walmsley M.E., Guille M.J., Bertwistle D., Smith J.C., Pizzey J.A., and Patient R.K. Negative control of Xenopus GATA-2 by activin and noggin with eventual expression in precursors of the ventral blood islands. Development 120 (1994) 2519-2529
73. Walters M.J., Wayman G.A., and Christian J.L. Bone morphogenetic protein function is required for terminal differentiation of the heart but not for early expression of cardiac marker genes. Mech. Dev. 100 (2001) 263-273
74. Walters M.J., Wayman G.A., Notis J.C., Goodman R.H., Soderling T.R., and Christian J.L. Calmodulin-dependent protein kinase IV mediated antagonism of BMP signaling regulates lineage and survival of hematopoietic progenitors. Development 129 (2002) 1455-1466
75. Wayman G.A., Walters M.J., Kolibaba K., Soderling T.R., and Christian J.L. CaM kinase IV regulates lineage commitment and survival of erythroid progenitors in a non-cell-autonomous manner. J. Cell Biol. 151 (2000) 811-824
76. Weber R., Blum B., and Muller P.R. The switch from larval to adult globin gene expression in Xenopus laevis is mediated by erythroid cells from distinct compartments. Development 112 (1991) 1021-1029
77. Winnier G., Blessing M., Labosky P.A., and Hogan B.L. Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse. Genes Dev. 9 (1995) 2105-2116
78. Zhang C., and Evans T. BMP-like signals are required after the midblastula transition for blood cell development. Dev. Genet. 18 (1996) 267-278
79. Zon L.I., Mather C., Burgess S., Bolce M.E., Harland R.M., and Orkin S.H. Expression of GATA-binding proteins during embryonic development in Xenopus laevis. Proc. Natl. Acad. Sci. U. S. A. 88 (1991) 10642