Pyrrolysyl-tRNA synthetase: An ordinary enzyme but an outstanding genetic code expansion tool

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1844, Issue 6, 2014, Pages 1059-1070

  Wan, Wei ^a   Tharp, Jeffery M ^a   Liu, Wenshe R ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

Author keywords

Amber codon; Genetic code expansion; Hydroxy acids; Non canonical amino acids; Pyrrolysine

Indexed keywords

2 HYDROXYACID; LYSINE DERIVATIVE; LYSINE TRANSFER RNA LIGASE; PYRROLYSYL TRNA SYNTHETASE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

AMINOACYLATION; ANTICODON; BIOSYNTHESIS; CRYSTAL STRUCTURE; CYCLOADDITION; ENZYME ACTIVITY; ENZYME ENGINEERING; EPIGENETICS; EUKARYOTIC CELL; GENE CLUSTER; GENETIC CODE; MAMMAL CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; REVIEW; SEQUENCE ALIGNMENT;

AMBER CODON; GENETIC CODE EXPANSION; HYDROXY ACIDS; NON-CANONICAL AMINO ACIDS; PYRROLYSINE;

AMINO ACYL-TRNA SYNTHETASES; CODON, TERMINATOR; GENETIC CODE; GENETIC ENGINEERING; LYSINE; METHANE; METHANOSARCINA; METHYLAMINES; MODELS, MOLECULAR; PROTEIN BIOSYNTHESIS; RNA, TRANSFER; SUBSTRATE SPECIFICITY;

EID: 84898629934     PISSN: 15709639     EISSN: 18781454     Source Type: Journal    
DOI: 10.1016/j.bbapap.2014.03.002     Document Type: Review

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