Genetically encoded light-activated transcription for spatiotemporal control of gene expression and gene silencing in mammalian cells

Journal of the American Chemical Society

Volumn 135, Issue 36, 2013, Pages 13433-13439

  Hemphill, James ^a,b   Chou, Chungjung ^a   Chin, Jason W ^c   Deiters, Alexander ^a,b  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

^c MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL FUNCTIONS; PROTEIN FUNCTIONS; SHORT HAIRPIN RNA; SPATIOTEMPORAL CONTROL; SYNTHETIC GENE NETWORK; T7 RNA POLYMERASE; TEMPORAL CONTROLS; UNNATURAL AMINO ACIDS;

AMINO ACIDS; GENES; PROTEINS; RNA;

TRANSCRIPTION;

AMINO ACID; LUCIFERASE; RNA POLYMERASE; SYNTHETIC DNA;

ANIMAL CELL; ARTICLE; BACTERIOPHAGE; CONTROLLED STUDY; GENE EXPRESSION REGULATION; GENE EXPRESSION SYSTEM; GENE SILENCING; GENETIC CODE; GENETIC TRANSCRIPTION; MAMMAL CELL; MUTAGENESIS; NONHUMAN; PHOTOCHEMISTRY; PROMOTER REGION; PROTEIN EXPRESSION; REPORTER GENE; SPATIOTEMPORAL ANALYSIS;

ACTIVATING TRANSCRIPTION FACTORS; DNA-DIRECTED RNA POLYMERASES; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE SILENCING; GREEN FLUORESCENT PROTEINS; HEK293 CELLS; HUMANS; LIGHT; LUCIFERASES; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PHOTOCHEMICAL PROCESSES; PROTEIN ENGINEERING; VIRAL PROTEINS;

EID: 84884192015     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja4051026     Document Type: Article

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