Copper-free sonogashira cross-coupling for functionalization of alkyne-encoded proteins in aqueous medium and in bacterial cells

Journal of the American Chemical Society

Volumn 133, Issue 39, 2011, Pages 15316-15319

  Li, Nan ^a   Lim, Reyna K V ^a   Edwardraja, Selvakumar ^a   Lin, Qing ^a  

^a UNIVERSITY AT BUFFALO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AQUEOUS MEDIUM; AROMATIC GROUP; AZIDE-ALKYNE CYCLOADDITION; BACTERIAL CELLS; BIOLOGICAL APPLICATIONS; BIOMOLECULAR DYNAMICS; CATALYTIC SYSTEM; CHEMICAL TOOLS; CLICK CHEMISTRY; COPPER-FREE SONOGASHIRA; FLUORINATED AROMATIC COMPOUNDS; FUNCTIONALIZATIONS; LIVING SYSTEMS; ORGANIC SYNTHESIS; SELECTIVE FUNCTIONALIZATION; SONOGASHIRA CROSS-COUPLING; UBIQUITIN;

ACETYLENE; AROMATIC COMPOUNDS; CHEMICAL BONDS; COPPER; CYCLOADDITION; ESCHERICHIA COLI; PALLADIUM; PALLADIUM COMPOUNDS; PROTEINS; SYNTHESIS (CHEMICAL);

COPPER COMPOUNDS;

ALKYNE; AMINOPYRIMIDINE PALLADIUM COMPLEX; AROMATIC COMPOUND; COPPER; HOMOPROPARGYLYCINE; PALLADIUM COMPLEX; PROPARGYLGLYCINE; PROTEIN; PYRIMIDINE DERIVATIVE; UBIQUITIN; UNCLASSIFIED DRUG;

AQUEOUS SOLUTION; ARTICLE; BACTERIAL CELL; CATALYSIS; ESCHERICHIA COLI; FLUORINATION; NONHUMAN; SONOGASHIRA REACTION;

ALKYNES; BACTERIAL PROTEINS; ESCHERICHIA COLI; GLYCINE; MODELS, MOLECULAR; PALLADIUM; PROTEIN CONFORMATION; SOLUBILITY; UBIQUITIN; WATER;

EID: 80053319803     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja2066913     Document Type: Article

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