A minicircuitry involving REST and CREB controls miR-9-2 expression during human neuronal differentiation

Nucleic Acids Research

Volumn 38, Issue 20, 2010, Pages 6895-6905

  Laneve, Pietro ^a,b   Gioia, Ubaldo ^a   Andriotto, Anastasia ^a   Moretti, Francesca ^a,c   Bozzoni, Irene ^a   Caffarelli, Elisa ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b CNRS   (France)

^c EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; MICRORNA; MICRORNA 9-2; RE1 SILENCING TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; EXON; FEEDBACK SYSTEM; GENE EXPRESSION; GENE LOCATION; GENE REPRESSION; HUMAN; HUMAN CELL; INTRON; NERVE CELL DIFFERENTIATION; NEUROBLASTOMA CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PHOSPHORYLATION; TRANSCRIPTION REGULATION;

CELL DIFFERENTIATION; CELLS, CULTURED; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; MICRORNAS; NEURONS; PROMOTER REGIONS, GENETIC; REPRESSOR PROTEINS; TRANSCRIPTION FACTORS; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION, GENETIC;

EID: 78649832226     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkq604     Document Type: Article

References (39)

1. Gao, F. B. (2008) Posttranscriptional control of neuronal development by microRNA networks. Trends Neurosci., 31, 20-26.
2. Schratt, G. (2009) microRNAs at the synapse. Nat Rev Neurosci., 10, 842-849.
3. Cullen, B. R. (2004) Transcription and processing of human microRNA precursors. Mol. Cell., 16, 861-865.
4. Kim, K. and Kim, V. N. (2007) Processing of intronic microRNAs. EMBO J., 26, 775-783.
5. Morlando, M., Ballarino, M., Gromak, N., Pagano, F., Bozzoni, I. and Proudfoot, N. J. (2008) Primary microRNA transcripts are processed co-transcriptionally. Nat. Struct. Mol. Biol., 15, 902-909.
6. Landgraf, P., Rusu, M., Sheridan, R., Sewer, A., Iovino, N., Aravin, A., Pfeffer, S., Rice, A., Kamphorst, A. O., Landthaler, M. et al. (2007) A mammalian microRNA expression atlas based on small RNA library sequencing. Cell, 129, 1401-1414.
7. Pasquinelli, A. E., Hunter, S. and Bracht, J. (2005) MicroRNAs: a developing story. Curr. Opin. Genet. Dev., 15, 200-205.
8. Calin, G. A. and Croce, C. M. (2006) MicroRNAs and chromosomal abnormalities in cancer cells. Oncogene, 25, 6202-6210.
9. Zhang, W., Dahlberg, J. E. and Tam, W. (2007) MicroRNAs in tumorigenesis: a primer. Am. J. Pathol., 171, 728-738.
10. Suzuki, H. I., Yamagata, K., Sugimoto, K., Iwamoto, T., Kato, S. and Miyazono, K. (2009) Modulation of microRNA processing by p53. Nature, 460, 529-533.
11. Lee, Y. S. and Dutta, A. (2009) MicroRNAs in cancer. Annu. Rev. Pathol., 4, 199-227.
12. Li, Y., Wang, F., Lee, J. A. and Gao, F. B. (2006) MicroRNA-9a ensures the precise specification of sensory organ precursors in Drosophila. Genes Dev., 20, 2793-2805.
13. Sempere, L. F., Freemantle, S., Pitha-Rowe, I., Moss, E., Dmitrovsky, E. and Ambros, V. (2004) Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation. Genome Biol., 5, R13.
14. Leucht, C., Stigloher, C., Wizenmann, A., Klafke, R., Folchert, A. and Bally-Cuif, L. (2008) MicroRNA-9 directs late organizer activity of the midbrain-hindbrain boundary. Nat. Neurosci., 11, 641-648.
15. Shibata, M., Kurokawa, D., Nakao, H., Ohmura, T. and Aizawa, S. (2008) MicroRNA-9 modulates Cajal-Retzius cell differentiation by suppressing Foxg1 expression in mouse medial pallium. J. Neurosci., 28, 10415-10421.
16. Ferretti, E., De Smaele, E., Po, A., Di Marcotullio, L., Tosi, E., Espinola, M. S., Di Rocco, C., Riccardi, R., Giangaspero, F., Farcomeni, A. et al. (2009) MicroRNA profiling in human medulloblastoma. Int. J. Cancer, 124, 568-577.
17. Laneve, P., Di Marcotullio, L., Gioia, U., Fiori, M. E., Ferretti, E., Gulino, A., Bozzoni, I. and Caffarelli, E. (2007) The interplay between microRNAs and the neurotrophin receptor tropomyosin-related kinase C controls proliferation of human neuroblastoma cells. Proc. Natl Acad. Sci. USA, 104, 7957-7962.
18. * regulates REST and CoREST and is downregulated in Huntington's disease. J. Neurosci., 28, 14341-14346.
19. Pall, G. S. and Hamilton, A. J. (2008) Improved northern blot method for enhanced detection of small RNA. Nat. Protoc., 3, 1077-1084.
20. Deo, M., Yu, J. Y., Chung, K. H., Tippens, M. and Turner, D. L. (2006) Detection of mammalian microRNA expression by in situ hybridization with RNA oligonucleotides. Dev. Dyn., 235, 2538-2548.
21. Guenther, M. G., Levine, S. S., Boyer, L. A., Jaenisch, R. and Young, R. A. (2007) A chromatin landmark and transcription initiation at most promoters in human cells. Cell, 130, 77-88.
22. Ozsolak, F., Poling, L. L., Wang, Z., Liu, H., Liu, X. S., Roeder, R. G., Zhang, X., Song, J. S. and Fisher, D. E. (2008) Chromatin structure analyses identify miRNA promoters. Genes Dev., 22, 3172-3183.
23. Heintzman, N. D., Stuart, R. K., Hon, G., Fu, Y., Ching, C. W., Hawkins, R. D., Barrera, L. O., Van Calcar, S., Qu, C., Ching, K. A. et al. (2007) Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome. Nat. Genet., 39, 311-318.
24. * during the neuronal differentiation of P19 cells. FEBS J., 275, 2605-2616.
25. Flavell, S. W., Kim, T. K., Gray, J. M., Harmin, D. A., Hemberg, M., Hong, E. J., Markenscoff-Papadimitriou, E., Bear, D. M. and Greenberg, M. E. (2008) Genome-wide analysis of MEF2 transcriptional program reveals synaptic target genes and neuronal activity-dependent polyadenylation site selection. Neuron., 60, 1022-1038.
26. Ji, Z., Lee, J. Y., Pan, Z., Jiang, B. and Tian, B. (2009) Progressive lengthening of 3′ untranslated regions of mRNAs by alternative polyadenylation during mouse embryonic development. Proc. Natl Acad. Sci. USA, 106, 7028-7033.
27. Krichevsky, A. M., Sonntag, K. C., Isacson, O. and Kosik, K. S. (2006) Specific microRNAs modulate embryonic stem cell-derived neurogenesis. Stem Cells, 24, 857-864.
28. Lukiw, W. J. and Pogue, A. I. (2007) Induction of specific micro RNA (miRNA) species by ROS-generating metal sulfates in primary human brain cells. J. Inorg. Biochem., 101, 1265-1269.
29. Croce, C. M. (2009) Causes and consequences of microRNA dysregulation in cancer. Nat. Rev. Genet., 10, 704-714.
30. Tonini, G. P. and Romani, M. (2003) Genetic and epigenetic alterations in neuroblastoma. Cancer Lett., 197, 69-73.
31. Wang, X., Xuan, Z., Zhao, X., Li, Y. and Zhang, M. Q. (2009) High-resolution human core-promoter prediction with CoreBoost-HM. Genome Res., 19, 266-275.
32. Monteys, A. M., Spengler, R. M., Wan, J., Tecedor, L., Lennox, K. A., Xing, Y. and Davidson, B. L. (2010) Structure and activity of putative intronic miRNA promoters. RNA, 16, 495-505.
33. Zhou, X., Ruan, J., Wang, G. and Zhang, W. (2007) Characterization and identification of microRNA core promoters in four model species. PLoS Comput. Biol., 3, e37.
34. Lunyak, V. V., Burgess, R., Prefontaine, G. G., Nelson, C., Sze, S. H., Chenoweth, J., Schwartz, P., Pevzner, P. A., Glass, C., Mandel, G. et al. (2002) Corepressor-dependent silencing of chromosomal regions encoding neuronal genes. Science, 298, 1747-1752.
35. Impey, S., Mark, M., Villacres, E. C., Poser, S., Chavkin, C. and Storm, D. R. (1996) Induction of CRE-mediated gene expression by stimuli that generate long-lasting LTP in area CA1 of the hippocampus. Neuron., 16, 973-982.
36. Vo, N., Klein, M. E., Varlamova, O., Keller, D. M., Yamamoto, T., Goodman, R. H. and Impey, S. (2005) A cAMP-response element binding protein-induced microRNA regulates neuronal morphogenesis. Proc. Natl Acad. Sci. USA, 102, 16426-16431.
37. Gonzalez, G. A. and Montminy, M. R. (1989) Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133. Cell, 59, 675-680.
38. Wu, J. and Xie, X. (2006) Comparative sequence analysis reveals an intricate network among REST, CREB and miRNA in mediating neuronal gene expression. Genome Biol, 7, R85.
39. Conaco, C., Otto, S., Han, J. J. and Mandel, G. (2006) Reciprocal actions of REST and a microRNA promote neuronal identity. Proc. Natl Acad. Sci. USA, 103, 2422-2427.