Targeted Gene Deletion of miRNAs in Mice by TALEN System

PLoS ONE

Volumn 8, Issue 10, 2013, Pages

  Takada, Shuji ^a   Sato, Tempei ^b   Ito, Yoshiaki ^b   Yamashita, Satoshi ^a   Kato, Tomoko ^a   Kawasumi, Miyuri ^c   Kanai Azuma, Masami ^c   Igarashi, Arisa ^a   Kato, Tomomi ^b   Tamano, Moe ^a   Asahara, Hiroshi ^a,b,d,e  

^a NATIONAL RESEARCH INSTITUTE FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

^b TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^c Japan Science and Technology Agency ^*  (Japan)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^e SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; NUCLEASE; TRANSCRIPTION ACTIVATOR LIKE EFFECTOR NUCLEASE; UNCLASSIFIED DRUG;

ALLELE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA MODIFICATION; EMBRYO; EMBRYO TRANSFER; FEMALE; GENE DELETION; GENE EXPRESSION; GENE TARGETING; HIGH THROUGHPUT SEQUENCING; KNOCKOUT MOUSE; MICROINJECTION; MOUSE; NONHUMAN; RNA EDITING;

ANIMALS; BASE SEQUENCE; DEOXYRIBONUCLEASES, TYPE II SITE-SPECIFIC; DNA, INTERGENIC; DNA-BINDING PROTEINS; EMBRYO, MAMMALIAN; FEMALE; GENE DELETION; GENE TARGETING; GENETIC ENGINEERING; MICE; MICE, INBRED ICR; MICROINJECTIONS; MICRORNAS; MOLECULAR SEQUENCE DATA; OOCYTES; RECOMBINANT FUSION PROTEINS;

EID: 84885703560     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0076004     Document Type: Article

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