Inositol pyrophosphates mediate chemotaxis in Dictyostelium via pleckstrin homology domain-Ptdins(3,4,5)P3 interactions

Cell

Volumn 114, Issue 5, 2003, Pages 559-572

  Luo, Hongbo R ^a   Huang, Yi Elaine ^a   Chen, Jianmeng C ^a   Saiardi, Adolfo ^a   Iijima, Miho ^a   Ye, Keqiang ^b   Huang, Yunfei ^a   Nagata, Eiichiro ^a   Devreotes, Peter ^a   Snyder, Solomon H ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIS DIPHOSPHOINOSITOL TETRAKISPHOSPHATE; CHEMOATTRACTANT; CYCLIC AMP; DIPHOSPHOINOSITOL PENTAKISPHOSPHATE; INOSITOL HEXAKISPHOSPHATE KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; PHOSPHOTRANSFERASE; PHYTIC ACID; PYROPHOSPHORIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CELL AGGREGATION; CELL MUTANT; CHEMOTAXIS; CONTROLLED STUDY; DICTYOSTELIUM; DOWNSTREAM PROCESSING; GENE DELETION; IN VITRO STUDY; IN VIVO STUDY; MEMBRANE TRANSPORT; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DEPLETION; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

DICTYOSTELIUM;

EID: 0141540848     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(03)00640-8     Document Type: Article

References (45)

1. Ali N., Duden R., Bembenek M.E., Shears S.B. The interaction of coatomer with inositol polyphosphates is conserved in Saccharomyces cerevisiae. Biochem. J. 310:1995;279-284.
2. Caffrey J.J., Safrany S.T., Yang X., Shears S.B. Discovery of molecular and catalytic diversity among human diphosphoinositol-polyphosphate phosphohydrolases. An expanding Nudt family. J. Biol. Chem. 275:2000; 12730-12736.
3. Cantley L.C. The phosphoinositide 3-kinase pathway. Science. 296:2002;1655-1657.
4. Chung C.Y., Funamoto S., Firtel R.A. Signaling pathways controlling cell polarity and chemotaxis. Trends Biochem. Sci. 26:2001;557-566.
5. Couchman J.R., Vogt S., Lim S.T., Lim Y., Oh E.S., Prestwich G.D., Theibert A., Lee W., Woods A. Regulation of inositol phospholipid binding and signaling through syndecan-4. J. Biol. Chem. 277:2002;49296-49303.
6. Cullen P.J., Hsuan J.J., Truong O., Letcher A.J., Jackson T.R., Dawson A.P., Irvine R.F. Identification of a specific Ins(1,3,4,5)P4-binding protein as a member of the GAP1 family. Nature. 376:1995;527-530.
7. Devreotes P., Janetopoulos C. Eukaryotic chemotaxis. distinctions between directional sensing and polarization J. Biol. Chem. 278:2003; 20445-20448.
8. Downward J. Mechanisms and consequences of activation of protein kinase B/Akt. Curr. Opin. Cell Biol. 10:1998;262-267.
9. Funamoto S., Milan K., Meili R., Firtel R.A. Role of phosphatidylinositol 3′ kinase and a downstream pleckstrin homology domain-containing protein in controlling chemotaxis in Dictyostelium. J. Cell Biol. 153:2001;795-810.
10. Funamoto S., Meili R., Lee S., Parry L., Firtel R.A. Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis. Cell. 109:2002;611-623.
11. Glennon M.C., Shears S.B. Turnover of inositol pentakisphosphates, inositol hexakisphosphate and diphosphoinositol polyphosphates in primary cultured hepatocytes. Biochem. J. 293:1993;583-590.
12. Hammonds-Odie L.P., Jackson T.R., Profit A.A., Blader I.J., Turck C.W., Prestwich G.D., Theibert A.B. Identification and cloning of centaurin-alpha. A novel phosphatidylinositol 3,4,5-trisphosphate-binding protein from rat brain. J. Biol. Chem. 271:1996;18859-18868.
13. Hanakahi L.A., West S.C. Specific interaction of IP6 with human Ku70/80, the DNA-binding subunit of DNA-PK. EMBO J. 21:2002;2038-2044.
14. Hemmings B.A. PtdIns(3,4,5)P3 gets its message across. Science. 277:1997;534.
15. Huang K.N., Symington L.S. Suppressors of a Saccharomyces cerevisiae pkc1 mutation identify alleles of the phosphatase gene PTC1 and of a novel gene encoding a putative basic leucine zipper protein. Genetics. 141:1995;1275-1285.
16. Huang C.F., Voglmaier S.M., Bembenek M.E., Saiardi A., Snyder S.H. Identification and purification of diphosphoinositol pentakisphosphate kinase, which synthesizes the inositol pyrophosphate bis(diphospho)inositol tetrakisphosphate. Biochemistry. 37:1998;14998-15004.
17. Huang Y.E., Iijima M., Parent C.A., Funamoto S., Firtel R., Devreotes P. Receptor-mediated regulation of PI3K3 confines PI(3,4,5)P3 to the leading edge of chemotaxing cells. Mol. Biol. Cell. 14:2003;1913-1922.
18. Iijima M., Devreotes P. Tumor suppressor PTEN mediates sensing of chemoattractant gradients. Cell. 109:2002;599-610.
19. Iijima M., Huang Y.E., Devreotes P. Temporal and spatial regulation of chemotaxis. Dev. Cell. 3:2002;469-478.
20. Irvine R.F., Schell M.J. Back in the water. the return of the inositol phosphates Nat. Rev. Mol. Cell Biol. 2:2001;327-338.
21. Konijn T.M. Microbiological assay of cyclic 3′,5′-AMP. Experientia. 26:1970;367-369.
22. Laussmann T., Pikzack C., Thiel U., Mayr G.W., Vogel G. Diphospho-myo-inositol phosphates during the life cycle of Dictyostelium and Polysphondylium. Eur. J. Biochem. 267:2000;2447-2451.
23. Lemmon M.A., Ferguson K.M. Signal-dependent membrane targeting by pleckstrin homology (PH) domains. Biochem. J. 350:2000;1-18.
24. Luo H.R., Saiardi A., Nagata E., Ye K., Yu H., Jung T.S., Luo X., Jain S., Sawa A., Snyder S.H. Grab. a physiologic guanine nucleotide exchange factor for rab3A, which interacts with inositol hexakisphosphate kinase Neuron. 31:2001;439-451.
25. Luo H.R., Saiardi A., Yu H., Nagata E., Ye K., Snyder S.H. Inositol pyrophosphates are required for DNA hyperrecombination in protein kinase c1 mutant yeast. Biochemistry. 41:2002;2509-2515.
26. Ma Y., Lieber M.R. Binding of inositol hexakisphosphate (IP6) to Ku but not to DNA-PKcs. J. Biol. Chem. 277:2002;10756-10759.
27. Maehama T., Dixon J.E. Pten. a tumour suppressor that functions as a phospholipid phosphatase Trends Cell Biol. 9:1999;125-128.
28. Mehrotra B., Elliott J.T., Chen J., Olszewski J.D., Profit A.A., Chaudhary A., Fukuda M., Mikoshiba K., Prestwich G.D. Selective photoaffinity labeling of the inositol polyphosphate binding C2B domains of synaptotagmins. J. Biol. Chem. 272:1997;4237-4244.
29. Menniti F.S., Miller R.N., Putney J.W. Jr., Shears S.B. Turnover of inositol polyphosphate pyrophosphates in pancreatoma cells. J. Biol. Chem. 268:1993;3850-3856.
30. Morrison B.H., Bauer J.A., Kalvakolanu D.V., Lindner D.J. Inositol hexakisphosphate kinase 2 mediates growth suppressive and apoptotic effects of interferon-beta in ovarian carcinoma cells. J. Biol. Chem. 276:2001;24965-24970.
31. Norris F.A., Ungewickell E., Majerus P.W. Inositol hexakisphosphate binds to clathrin assembly protein 3 (AP-3/AP180) and inhibits clathrin cage assembly in vitro. J. Biol. Chem. 270:1995;214-217.
32. Parent C.A., Devreotes P.N. Molecular genetics of signal transduction in Dictyostelium. Annu. Rev. Biochem. 65:1996;411-440.
33. Parent C.A., Blacklock B.J., Froehlich W.M., Murphy D.B., Devreotes P.N. G protein signaling events are activated at the leading edge of chemotactic cells. Cell. 95:1998;81-91.
34. Safrany S.T., Shears S.B. Turnover of bis-diphosphoinositol tetrakisphosphate in a smooth muscle cell line is regulated by beta2-adrenergic receptors through a cAMP-mediated, A-kinase-independent mechanism. EMBO J. 17:1998;1710-1716.
35. Saiardi A., Erdjument-Bromage H., Snowman A.M., Tempst P., Snyder S.H. Synthesis of diphosphoinositol pentakisphosphate by a newly identified family of higher inositol polyphosphate kinases. Curr. Biol. 9:1999;1323-1326.
36. Saiardi A., Nagata E., Luo H.R., Snowman A.M., Snyder S.H. Identification and characterization of a novel inositol hexakisphosphate kinase. J. Biol. Chem. 276:2001;39179-39185.
37. Saiardi A., Sciambi C., McCaffery J.M., Wendland B., Snyder S.H. Inositol pyrophosphates regulate endocytic trafficking. Proc. Natl. Acad. Sci. USA. 99:2002;14206-14211.
38. Schell M.J., Letcher A.J., Brearley C.A., Biber J., Murer H., Irvine R.F. PiUS (Pi uptake stimulator) is an inositol hexakisphosphate kinase. FEBS Lett. 461:1999;169-172.
39. Stephens L., Radenberg T., Thiel U., Vogel G., Khoo K.H., Dell A., Jackson T.R., Hawkins P.T., Mayr G.W. The detection, purification, structural characterization, and metabolism of diphosphoinositol pentakisphosphate(s) and bisdiphosphoinositol tetrakisphosphate(s). J. Biol. Chem. 268:1993;4009-4015.
40. Venkateswarlu K., Gunn-Moore F., Oatey P.B., Tavare J.M., Cullen P.J. Nerve growth factor- and epidermal growth factor-stimulated translocation of the ADP-ribosylation factor-exchange factor GRP1 to the plasma membrane of PC12 cells requires activation of phosphatidylinositol 3-kinase and the GRP1 pleckstrin homology domain. Biochem. J. 335:1998;139-146.
41. Voglmaier S.M., Keen J.H., Murphy J.E., Ferris C.D., Prestwich G.D., Snyder S.H., Theibert A.B. Inositol hexakisphosphate receptor identified as the clathrin assembly protein AP-2. Biochem. Biophys. Res. Commun. 187:1992;158-163.
42. Wang D.S., Deng T., Shaw G. Membrane binding and enzymatic activation of a Dbl homology domain require the neighboring pleckstrin homology domain. Biochem. Biophys. Res. Commun. 234:1997;183-189.
43. Williams R.S., Eames M., Ryves W.J., Viggars J., Harwood A.J. Loss of a prolyl oligopeptidase confers resistance to lithium by elevation of inositol (1,4,5) trisphosphate. EMBO J. 18:1999;2734-2745.
44. Ye W., Ali N., Bembenek M.E., Shears S.B., Lafer E.M. Inhibition of clathrin assembly by high affinity binding of specific inositol polyphosphates to the synapse-specific clathrin assembly protein AP-3. J. Biol. Chem. 270:1995;1564-1568.
45. Ye K., Hurt K.J., Wu F.Y., Fang M., Luo H.R., Hong J.J., Blackshaw S., Ferris C.D., Snyder S.H. Pike. A nuclear GTPase that enhances PI. 3-kinase(activity and is regulated by protein 4.1N. Cell 103):2000;919-930.