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Volumn 5, Issue MAR, 2014, Pages

Toll-like receptors and skin cancer

Author keywords

BCC; Innate immunity; Melanoma; Non melanoma skin cancer; SCC; Toll like receptor

Indexed keywords

AGATOLIMOD; ALPHA INTERFERON; GAMMA INTERFERON; HIGH MOBILITY GROUP B1 PROTEIN; IMIQUIMOD; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 18; LIGAND; MYELOID DIFFERENTIATION FACTOR 88; PACLITAXEL; RESIQUIMOD; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 10; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 5; TOLL LIKE RECEPTOR 6; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; TOLL LIKE RECEPTOR 9; TOLL LIKE RECEPTOR AGONIST; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; UNINDEXED DRUG; VACCINE;

EID: 84897949357     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2014.00135     Document Type: Article
Times cited : (37)

References (69)
  • 1
    • 77949405816 scopus 로고    scopus 로고
    • Incidence estimate of nonmelanoma skin cancer in the United States, 2006
    • doi:10.1001/archdermatol.2010.19
    • Rogers HW, Weinstock MA, Harris AR, Hinckley MR, Feldman SR, Fleischer AB, et al. Incidence estimate of nonmelanoma skin cancer in the United States, 2006. Arch Dermatol (2010) 146(3):283-7. doi:10.1001/archdermatol.2010.19
    • (2010) Arch Dermatol , vol.146 , Issue.3 , pp. 283-287
    • Rogers, H.W.1    Weinstock, M.A.2    Harris, A.R.3    Hinckley, M.R.4    Feldman, S.R.5    Fleischer, A.B.6
  • 2
    • 84897953893 scopus 로고    scopus 로고
    • American Cancer Society.
    • American Cancer Society. What are the Risk Factors for Basal and Squamous Cell Skin Cancers. (2013). Available from: www.cancer.org/cancer/skincancer-basalandsquamouscell/detailedguide/skin-cancer-basal-and-squamous-cell-risk-factors
    • (2013) What are the Risk Factors for Basal and Squamous Cell Skin Cancers
  • 3
    • 84877831775 scopus 로고    scopus 로고
    • Cutaneous squamous cell carcinoma: estimated incidence of disease, nodal metastasis, and deaths from disease in the United States, 2012
    • Karia PS, Han J, Schmults CD. Cutaneous squamous cell carcinoma: estimated incidence of disease, nodal metastasis, and deaths from disease in the United States, 2012. J Am Acad Dermatol (2013) 68(6):957-66.
    • (2013) J Am Acad Dermatol , vol.68 , Issue.6 , pp. 957-966
    • Karia, P.S.1    Han, J.2    Schmults, C.D.3
  • 5
    • 0003964363 scopus 로고    scopus 로고
    • American Cancer Society.
    • American Cancer Society. Cancer Facts & Figures. (2013). Available from: www.cancer.org/acs/groups/content/@epidemiologysurveilance/documents/document/acspc-036845.pdf
    • (2013) Cancer Facts & Figures
  • 7
    • 1542615639 scopus 로고    scopus 로고
    • Immune surveillance in the skin: mechanisms and clinical consequences
    • doi:10.1038/nri1310
    • Kupper TS, Fuhlbrigge RC. Immune surveillance in the skin: mechanisms and clinical consequences. Nat Rev Immunol (2004) 4(3):211-22. doi:10.1038/nri1310
    • (2004) Nat Rev Immunol , vol.4 , Issue.3 , pp. 211-222
    • Kupper, T.S.1    Fuhlbrigge, R.C.2
  • 8
    • 0037250369 scopus 로고    scopus 로고
    • Keratinocyte expression of human beta defensin 2 following bacterial infection: role in cutaneous host defense
    • doi:10.1128/CDLI.10.1.161-166.2003
    • Dinulos JG, Mentele L, Fredericks LP, Dale BA, Darmstadt GL. Keratinocyte expression of human beta defensin 2 following bacterial infection: role in cutaneous host defense. Clin Diagn Lab Immunol (2003) 10(1):161-6. doi:10.1128/CDLI.10.1.161-166.2003
    • (2003) Clin Diagn Lab Immunol , vol.10 , Issue.1 , pp. 161-166
    • Dinulos, J.G.1    Mentele, L.2    Fredericks, L.P.3    Dale, B.A.4    Darmstadt, G.L.5
  • 9
    • 0346881404 scopus 로고    scopus 로고
    • Innate immune response of oral and foreskin keratinocytes: utilization of different signaling pathways by various bacterial species
    • doi:10.1128/IAI.72.1.352-358.2004
    • Chung WO, Dale BA. Innate immune response of oral and foreskin keratinocytes: utilization of different signaling pathways by various bacterial species. Infect Immun (2004) 72(1):352-8. doi:10.1128/IAI.72.1.352-358.2004
    • (2004) Infect Immun , vol.72 , Issue.1 , pp. 352-358
    • Chung, W.O.1    Dale, B.A.2
  • 10
    • 0036041553 scopus 로고    scopus 로고
    • Human keratinocytes express functional CD14 and toll-like receptor 4
    • doi:10.1046/j.1523-1747.2002.01847.x
    • Song PI, Park YM, Abraham T, Harten B, Zivony A, Neparidze N, et al. Human keratinocytes express functional CD14 and toll-like receptor 4. J Invest Dermatol (2002) 119(2):424-32. doi:10.1046/j.1523-1747.2002.01847.x
    • (2002) J Invest Dermatol , vol.119 , Issue.2 , pp. 424-432
    • Song, P.I.1    Park, Y.M.2    Abraham, T.3    Harten, B.4    Zivony, A.5    Neparidze, N.6
  • 11
    • 0036890119 scopus 로고    scopus 로고
    • Expression of functional Toll-like receptor 2 on human epidermal keratinocytes
    • doi:10.1016/S0923-1811(02)00105-6
    • Kawai K, Shimura H, Minagawa M, Ito A, Tomiyama K, Ito M. Expression of functional Toll-like receptor 2 on human epidermal keratinocytes. J Dermatol Sci (2002) 30(3):185-94. doi:10.1016/S0923-1811(02)00105-6
    • (2002) J Dermatol Sci , vol.30 , Issue.3 , pp. 185-194
    • Kawai, K.1    Shimura, H.2    Minagawa, M.3    Ito, A.4    Tomiyama, K.5    Ito, M.6
  • 12
    • 0038579508 scopus 로고    scopus 로고
    • Normal keratinocytes express Toll-like receptors (TLRs) 1, 2 and 5: modulation of TLR expression in chronic plaque psoriasis
    • doi:10.1046/j.1365-2133.2003.05287.x
    • Baker BS, Ovigne JM, Powles AV, Corcoran S, Fry L. Normal keratinocytes express Toll-like receptors (TLRs) 1, 2 and 5: modulation of TLR expression in chronic plaque psoriasis. Br J Dermatol (2003) 148(4):670-9. doi:10.1046/j.1365-2133.2003.05287.x
    • (2003) Br J Dermatol , vol.148 , Issue.4 , pp. 670-679
    • Baker, B.S.1    Ovigne, J.M.2    Powles, A.V.3    Corcoran, S.4    Fry, L.5
  • 13
    • 0038281539 scopus 로고    scopus 로고
    • Expression and function of Toll-like receptors 2 and 4 in human keratinocytes
    • doi:10.1093/intimm/dxg068
    • Pivarcsi A, Bodai L, Rethi B, Kenderessy-Szabo A, Koreck A, Szell M, et al. Expression and function of Toll-like receptors 2 and 4 in human keratinocytes. Int Immunol (2003) 15(6):721-30. doi:10.1093/intimm/dxg068
    • (2003) Int Immunol , vol.15 , Issue.6 , pp. 721-730
    • Pivarcsi, A.1    Bodai, L.2    Rethi, B.3    Kenderessy-Szabo, A.4    Koreck, A.5    Szell, M.6
  • 15
    • 79955586582 scopus 로고    scopus 로고
    • Activation of Toll-like Receptors 1, 2, 4, 5, and 7 on Human melanocytes modulate pigmentation
    • doi:10.5021/ad.2010.22.4.486
    • Jin SH, Kang HY. Activation of Toll-like Receptors 1, 2, 4, 5, and 7 on Human melanocytes modulate pigmentation. Ann Dermatol (2010) 22(4):486-9. doi:10.5021/ad.2010.22.4.486
    • (2010) Ann Dermatol , vol.22 , Issue.4 , pp. 486-489
    • Jin, S.H.1    Kang, H.Y.2
  • 16
    • 0037460116 scopus 로고    scopus 로고
    • Recognition of pathogen-associated molecular patterns by TLR family
    • doi:10.1016/S0165-2478(02)00228-6
    • Akira S, Hemmi H. Recognition of pathogen-associated molecular patterns by TLR family. Immunol Lett (2003) 85(2):85-95. doi:10.1016/S0165-2478(02)00228-6
    • (2003) Immunol Lett , vol.85 , Issue.2 , pp. 85-95
    • Akira, S.1    Hemmi, H.2
  • 17
    • 2942679083 scopus 로고    scopus 로고
    • The immunobiology of the TLR9 subfamily
    • doi:10.1016/j.it.2004.04.011
    • Wagner H. The immunobiology of the TLR9 subfamily. Trends Immunol (2004) 25(7):381-6. doi:10.1016/j.it.2004.04.011
    • (2004) Trends Immunol , vol.25 , Issue.7 , pp. 381-386
    • Wagner, H.1
  • 18
    • 0012929728 scopus 로고    scopus 로고
    • Toll-like receptors
    • doi:10.1146/annurev.immunol.21.120601.141126
    • Takeda K, Kaisho T, Akira S. Toll-like receptors. Annu Rev Immunol (2003) 21:335-76. doi:10.1146/annurev.immunol.21.120601.141126
    • (2003) Annu Rev Immunol , vol.21 , pp. 335-376
    • Takeda, K.1    Kaisho, T.2    Akira, S.3
  • 19
    • 0035524488 scopus 로고    scopus 로고
    • Toll-like receptors and innate immunity
    • doi:10.1038/35100529
    • Medzhitov R. Toll-like receptors and innate immunity. Nat Rev Immunol (2001) 1(2):135-45. doi:10.1038/35100529
    • (2001) Nat Rev Immunol , vol.1 , Issue.2 , pp. 135-145
    • Medzhitov, R.1
  • 20
    • 0034601309 scopus 로고    scopus 로고
    • Innate immunity
    • doi:10.1056/NEJM200008033430506
    • Medzhitov R, Janeway C Jr. Innate immunity. N Engl J Med (2000) 343(5):338-44. doi:10.1056/NEJM200008033430506
    • (2000) N Engl J Med , vol.343 , Issue.5 , pp. 338-344
    • Medzhitov, R.1    Janeway Jr., C.2
  • 21
    • 5444262511 scopus 로고    scopus 로고
    • Toll-like receptor control of the adaptive immune responses
    • doi:10.1038/ni1112
    • Iwasaki A, Medzhitov R. Toll-like receptor control of the adaptive immune responses. Nat Immunol (2004) 5(10):987-95. doi:10.1038/ni1112
    • (2004) Nat Immunol , vol.5 , Issue.10 , pp. 987-995
    • Iwasaki, A.1    Medzhitov, R.2
  • 22
    • 0034886143 scopus 로고    scopus 로고
    • Toll-like receptors: critical proteins linking innate and acquired immunity
    • doi:10.1038/90609
    • Akira S, Takeda K, Kaisho T. Toll-like receptors: critical proteins linking innate and acquired immunity. Nat Immunol (2001) 2(8):675-80. doi:10.1038/90609
    • (2001) Nat Immunol , vol.2 , Issue.8 , pp. 675-680
    • Akira, S.1    Takeda, K.2    Kaisho, T.3
  • 23
    • 58149360792 scopus 로고    scopus 로고
    • Imiquimod, a Toll-like receptor 7 agonist, inhibits melanogenesis and proliferation of human melanocytes
    • doi:10.1038/jid.2008.184
    • Kang HY, Park TJ, Jin SH. Imiquimod, a Toll-like receptor 7 agonist, inhibits melanogenesis and proliferation of human melanocytes. J Invest Dermatol (2009) 129(1):243-6. doi:10.1038/jid.2008.184
    • (2009) J Invest Dermatol , vol.129 , Issue.1 , pp. 243-246
    • Kang, H.Y.1    Park, T.J.2    Jin, S.H.3
  • 24
    • 33845951211 scopus 로고    scopus 로고
    • DAMPs, PAMPs and alarmins: all we need to know about danger
    • doi:10.1189/jlb.0306164
    • Bianchi ME. DAMPs, PAMPs and alarmins: all we need to know about danger. J Leukoc Biol (2007) 81(1):1-5. doi:10.1189/jlb.0306164
    • (2007) J Leukoc Biol , vol.81 , Issue.1 , pp. 1-5
    • Bianchi, M.E.1
  • 25
    • 78649696296 scopus 로고    scopus 로고
    • Endogenous toll-like receptor ligands and their biological significance
    • doi:10.1111/j.1582-4934.2010.01127.x
    • Yu L, Wang L, Chen S. Endogenous toll-like receptor ligands and their biological significance. J Cell Mol Med (2010) 14(11):2592-603. doi:10.1111/j.1582-4934.2010.01127.x
    • (2010) J Cell Mol Med , vol.14 , Issue.11 , pp. 2592-2603
    • Yu, L.1    Wang, L.2    Chen, S.3
  • 26
    • 35748945719 scopus 로고    scopus 로고
    • The grateful dead: damage-associated molecular pattern molecules and reduction/oxidation regulate immunity
    • doi:10.1111/j.1600-065X.2007.00579.x
    • Lotze MT, Zeh HJ, Rubartelli A, Sparvero LJ, Amoscato AA, Washburn NR, et al. The grateful dead: damage-associated molecular pattern molecules and reduction/oxidation regulate immunity. Immunol Rev (2007) 220:60-81. doi:10.1111/j.1600-065X.2007.00579.x
    • (2007) Immunol Rev , vol.220 , pp. 60-81
    • Lotze, M.T.1    Zeh, H.J.2    Rubartelli, A.3    Sparvero, L.J.4    Amoscato, A.A.5    Washburn, N.R.6
  • 27
    • 0037062934 scopus 로고    scopus 로고
    • Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
    • doi:10.1038/nature00858
    • Scaffidi P, Misteli T, Bianchi ME. Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature (2002) 418(6894):191-5. doi:10.1038/nature00858
    • (2002) Nature , vol.418 , Issue.6894 , pp. 191-195
    • Scaffidi, P.1    Misteli, T.2    Bianchi, M.E.3
  • 28
    • 41049117932 scopus 로고    scopus 로고
    • Convergence and amplification of toll-like receptor (TLR) and receptor for advanced glycation end products (RAGE) signaling pathways via high mobility group B1 (HMGB1)
    • doi:10.1007/s10456-008-9093-5
    • van Beijnum JR, Buurman WA, Griffioen AW. Convergence and amplification of toll-like receptor (TLR) and receptor for advanced glycation end products (RAGE) signaling pathways via high mobility group B1 (HMGB1). Angiogenesis (2008) 11(1):91-9. doi:10.1007/s10456-008-9093-5
    • (2008) Angiogenesis , vol.11 , Issue.1 , pp. 91-99
    • van Beijnum, J.R.1    Buurman, W.A.2    Griffioen, A.W.3
  • 29
    • 3142724031 scopus 로고    scopus 로고
    • Toll-like receptor signalling
    • doi:10.1038/nri1391
    • Akira S, Takeda K. Toll-like receptor signalling. Nat Rev Immunol (2004) 4(7):499-511. doi:10.1038/nri1391
    • (2004) Nat Rev Immunol , vol.4 , Issue.7 , pp. 499-511
    • Akira, S.1    Takeda, K.2
  • 30
    • 33947694370 scopus 로고    scopus 로고
    • TLR signaling
    • doi:10.1016/j.smim.2006.12.004
    • Kawai T, Akira S. TLR signaling. Semin Immunol (2007) 19(1):24-32. doi:10.1016/j.smim.2006.12.004
    • (2007) Semin Immunol , vol.19 , Issue.1 , pp. 24-32
    • Kawai, T.1    Akira, S.2
  • 31
    • 0036546501 scopus 로고    scopus 로고
    • NF-kappaB in cancer: from innocent bystander to major culprit
    • doi:10.1038/nrc780
    • Karin M, Cao Y, Greten FR, Li ZW. NF-kappaB in cancer: from innocent bystander to major culprit. Nat Rev Cancer (2002) 2(4):301-10. doi:10.1038/nrc780
    • (2002) Nat Rev Cancer , vol.2 , Issue.4 , pp. 301-310
    • Karin, M.1    Cao, Y.2    Greten, F.R.3    Li, Z.W.4
  • 32
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • doi:10.1038/nature01322
    • Coussens LM, Werb Z. Inflammation and cancer. Nature (2002) 420(6917):860-7. doi:10.1038/nature01322
    • (2002) Nature , vol.420 , Issue.6917 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2
  • 33
    • 19844373824 scopus 로고    scopus 로고
    • Soluble mediators of inflammation during tumor development
    • doi:10.1016/S0065-230X(05)93005-4
    • Robinson SC, Coussens LM. Soluble mediators of inflammation during tumor development. Adv Cancer Res (2005) 93:159-87. doi:10.1016/S0065-230X(05)93005-4
    • (2005) Adv Cancer Res , vol.93 , pp. 159-187
    • Robinson, S.C.1    Coussens, L.M.2
  • 34
    • 70350664389 scopus 로고    scopus 로고
    • Cancer cells expressing Toll-like receptors and the tumor microenvironment
    • doi:10.1007/s12307-009-0022-y
    • Sato Y, Goto Y, Narita N, Hoon DS. Cancer cells expressing Toll-like receptors and the tumor microenvironment. Cancer Microenviron (2009) 2(Suppl 1):205-14. doi:10.1007/s12307-009-0022-y
    • (2009) Cancer Microenviron , vol.2 , Issue.SUPPL. 1 , pp. 205-214
    • Sato, Y.1    Goto, Y.2    Narita, N.3    Hoon, D.S.4
  • 35
    • 84864052420 scopus 로고    scopus 로고
    • Icariside II potentiates paclitaxel-induced apoptosis in human melanoma A375 cells by inhibiting TLR4 signaling pathway
    • doi:10.1016/j.fct.2012.06.027
    • Wu J, Guan M, Wong PF, Yu H, Dong J, Xu J. Icariside II potentiates paclitaxel-induced apoptosis in human melanoma A375 cells by inhibiting TLR4 signaling pathway. Food Chem Toxicol (2012) 50(9):3019-24. doi:10.1016/j.fct.2012.06.027
    • (2012) Food Chem Toxicol , vol.50 , Issue.9 , pp. 3019-3024
    • Wu, J.1    Guan, M.2    Wong, P.F.3    Yu, H.4    Dong, J.5    Xu, J.6
  • 36
    • 56249098670 scopus 로고    scopus 로고
    • Activation of Toll-like receptors 2, 3, and 4 on human melanoma cells induces inflammatory factors
    • doi:10.1158/1535-7163.MCT-08-0582
    • Goto Y, Arigami T, Kitago M, Nguyen SL, Narita N, Ferrone S, et al. Activation of Toll-like receptors 2, 3, and 4 on human melanoma cells induces inflammatory factors. Mol Cancer Ther (2008) 7(11):3642-53. doi:10.1158/1535-7163.MCT-08-0582
    • (2008) Mol Cancer Ther , vol.7 , Issue.11 , pp. 3642-3653
    • Goto, Y.1    Arigami, T.2    Kitago, M.3    Nguyen, S.L.4    Narita, N.5    Ferrone, S.6
  • 38
    • 34547665101 scopus 로고    scopus 로고
    • Toll-like receptor 3 expressed by melanoma cells as a target for therapy?
    • doi:10.1158/1078-0432.CCR-07-0274
    • Salaun B, Lebecque S, Matikainen S, Rimoldi D, Romero P. Toll-like receptor 3 expressed by melanoma cells as a target for therapy? Clin Cancer Res (2007) 13(15 Pt 1):4565-74. doi:10.1158/1078-0432.CCR-07-0274
    • (2007) Clin Cancer Res , vol.13 , Issue.15 PART 1 , pp. 4565-4574
    • Salaun, B.1    Lebecque, S.2    Matikainen, S.3    Rimoldi, D.4    Romero, P.5
  • 39
    • 77954951851 scopus 로고    scopus 로고
    • TLR4-mediated skin carcinogenesis is dependent on immune and radioresistant cells
    • doi:10.1038/emboj.2010.94
    • Mittal D, Saccheri F, Venereau E, Pusterla T, Bianchi ME, Rescigno M. TLR4-mediated skin carcinogenesis is dependent on immune and radioresistant cells. EMBO J (2010) 29(13):2242-52. doi:10.1038/emboj.2010.94
    • (2010) EMBO J , vol.29 , Issue.13 , pp. 2242-2252
    • Mittal, D.1    Saccheri, F.2    Venereau, E.3    Pusterla, T.4    Bianchi, M.E.5    Rescigno, M.6
  • 40
    • 77953149707 scopus 로고    scopus 로고
    • Toll-like receptor 9 agonists up-regulates the expression of cyclooxygenase-2 via activation of NF-kappaB in prostate cancer cells
    • doi:10.1007/s11033-009-9620-5
    • Di JM, Pang J, Sun QP, Zhang Y, Fang YQ, Liu XP, et al. Toll-like receptor 9 agonists up-regulates the expression of cyclooxygenase-2 via activation of NF-kappaB in prostate cancer cells. Mol Biol Rep (2010) 37(4):1849-55. doi:10.1007/s11033-009-9620-5
    • (2010) Mol Biol Rep , vol.37 , Issue.4 , pp. 1849-1855
    • Di, J.M.1    Pang, J.2    Sun, Q.P.3    Zhang, Y.4    Fang, Y.Q.5    Liu, X.P.6
  • 41
    • 42549088640 scopus 로고    scopus 로고
    • Functional expression of TLR9 is associated to the metastatic potential of human lung cancer cell: functional active role of TLR9 on tumor metastasis
    • doi:10.4161/cbt.6.11.4826
    • Ren T, Wen ZK, Liu ZM, Liang YJ, Guo ZL, Xu L. Functional expression of TLR9 is associated to the metastatic potential of human lung cancer cell: functional active role of TLR9 on tumor metastasis. Cancer Biol Ther (2007) 6(11):1704-9. doi:10.4161/cbt.6.11.4826
    • (2007) Cancer Biol Ther , vol.6 , Issue.11 , pp. 1704-1709
    • Ren, T.1    Wen, Z.K.2    Liu, Z.M.3    Liang, Y.J.4    Guo, Z.L.5    Xu, L.6
  • 42
    • 67649777060 scopus 로고    scopus 로고
    • Toll-like receptor 9 agonists promote IL-8 and TGF-beta1 production via activation of nuclear factor kappaB in PC-3 cells
    • doi:10.1016/j.cancergencyto.2009.03.006
    • Di JM, Pang J, Pu XY, Zhang Y, Liu XP, Fang YQ, et al. Toll-like receptor 9 agonists promote IL-8 and TGF-beta1 production via activation of nuclear factor kappaB in PC-3 cells. Cancer Genet Cytogenet (2009) 192(2):60-7. doi:10.1016/j.cancergencyto.2009.03.006
    • (2009) Cancer Genet Cytogenet , vol.192 , Issue.2 , pp. 60-67
    • Di, J.M.1    Pang, J.2    Pu, X.Y.3    Zhang, Y.4    Liu, X.P.5    Fang, Y.Q.6
  • 43
    • 84857446575 scopus 로고    scopus 로고
    • Toll-like receptor 3-mediated tumor invasion in head and neck cancer
    • doi:10.1016/j.oraloncology.2011.10.008
    • Chuang HC, Huang CC, Chien CY, Chuang JH. Toll-like receptor 3-mediated tumor invasion in head and neck cancer. Oral Oncol (2012) 48(3):226-32. doi:10.1016/j.oraloncology.2011.10.008
    • (2012) Oral Oncol , vol.48 , Issue.3 , pp. 226-232
    • Chuang, H.C.1    Huang, C.C.2    Chien, C.Y.3    Chuang, J.H.4
  • 44
    • 20444432334 scopus 로고    scopus 로고
    • Toll-like receptors on tumor cells facilitate evasion of immune surveillance
    • doi:10.1158/0008-5472.CAN-05-0784
    • Huang B, Zhao J, Li H, He KL, Chen Y, Chen SH, et al. Toll-like receptors on tumor cells facilitate evasion of immune surveillance. Cancer Res (2005) 65(12):5009-14. doi:10.1158/0008-5472.CAN-05-0784
    • (2005) Cancer Res , vol.65 , Issue.12 , pp. 5009-5014
    • Huang, B.1    Zhao, J.2    Li, H.3    He, K.L.4    Chen, Y.5    Chen, S.H.6
  • 45
    • 70349982431 scopus 로고    scopus 로고
    • HMGB1 mediates endogenous TLR2 activation and brain tumor regression
    • doi:10.1371/journal.pmed.1000010
    • Curtin JF, Liu N, Candolfi M, Xiong W, Assi H, Yagiz K, et al. HMGB1 mediates endogenous TLR2 activation and brain tumor regression. PLoS Med (2009) 6(1):e10. doi:10.1371/journal.pmed.1000010
    • (2009) PLoS Med , vol.6 , Issue.1
    • Curtin, J.F.1    Liu, N.2    Candolfi, M.3    Xiong, W.4    Assi, H.5    Yagiz, K.6
  • 46
    • 17844384773 scopus 로고    scopus 로고
    • Defining the antigen-specific T-cell response to vaccination and poly(I:C)/TLR3 signaling: evidence of enhanced primary and memory CD8 T-cell responses and antitumor immunity
    • doi:10.1097/01.cji.0000156828.75196.0d
    • Salem ML, Kadima AN, Cole DJ, Gillanders WE. Defining the antigen-specific T-cell response to vaccination and poly(I:C)/TLR3 signaling: evidence of enhanced primary and memory CD8 T-cell responses and antitumor immunity. J Immunother (2005) 28(3):220-8. doi:10.1097/01.cji.0000156828.75196.0d
    • (2005) J Immunother , vol.28 , Issue.3 , pp. 220-228
    • Salem, M.L.1    Kadima, A.N.2    Cole, D.J.3    Gillanders, W.E.4
  • 47
    • 0242580118 scopus 로고    scopus 로고
    • Cutting edge: different Toll-like receptor agonists instruct dendritic cells to induce distinct Th responses via differential modulation of extracellular signal-regulated kinase-mitogen-activated protein kinase and c-Fos
    • Agrawal S, Agrawal A, Doughty B, Gerwitz A, Blenis J, Van Dyke T, et al. Cutting edge: different Toll-like receptor agonists instruct dendritic cells to induce distinct Th responses via differential modulation of extracellular signal-regulated kinase-mitogen-activated protein kinase and c-Fos. J Immunol (2003) 171(10):4984-9.
    • (2003) J Immunol , vol.171 , Issue.10 , pp. 4984-4989
    • Agrawal, S.1    Agrawal, A.2    Doughty, B.3    Gerwitz, A.4    Blenis, J.5    Van Dyke, T.6
  • 48
    • 1542435161 scopus 로고    scopus 로고
    • Actinic keratosis treated with an immune response modifier: a case report of six patients
    • doi:10.1046/j.1365-2230.28.s1.13.x
    • Bianchi L, Campione E, Marulli GC, Costanzo A, Chimenti S. Actinic keratosis treated with an immune response modifier: a case report of six patients. Clin Exp Dermatol (2003) 28(Suppl 1):39-41. doi:10.1046/j.1365-2230.28.s1.13.x
    • (2003) Clin Exp Dermatol , vol.28 , Issue.SUPPL. 1 , pp. 39-41
    • Bianchi, L.1    Campione, E.2    Marulli, G.C.3    Costanzo, A.4    Chimenti, S.5
  • 49
    • 1842586450 scopus 로고    scopus 로고
    • Superficial and nodular basal cell carcinomas treated with an immune response modifier: a report of seven patients
    • doi:10.1046/j.1365-2230.28.s1.13.x
    • Bianchi L, Costanzo A, Campione E, Nistico S, Chimenti S. Superficial and nodular basal cell carcinomas treated with an immune response modifier: a report of seven patients. Clin Exp Dermatol (2003) 28(Suppl 1):24-6. doi:10.1046/j.1365-2230.28.s1.13.x
    • (2003) Clin Exp Dermatol , vol.28 , Issue.SUPPL. 1 , pp. 24-26
    • Bianchi, L.1    Costanzo, A.2    Campione, E.3    Nistico, S.4    Chimenti, S.5
  • 50
    • 1242303458 scopus 로고    scopus 로고
    • Treatment of Bowen's disease using a cycle regimen of imiquimod 5% cream
    • doi:10.1046/j.1365-2230.28.s1.4.x
    • Chen K, Shumack S. Treatment of Bowen's disease using a cycle regimen of imiquimod 5% cream. Clin Exp Dermatol (2003) 28(Suppl 1):10-2. doi:10.1046/j.1365-2230.28.s1.4.x
    • (2003) Clin Exp Dermatol , vol.28 , Issue.SUPPL. 1 , pp. 10-12
    • Chen, K.1    Shumack, S.2
  • 51
    • 1542644920 scopus 로고    scopus 로고
    • The treatment of basal cell carcinomas in a patient with xeroderma pigmentosum with a combination of imiquimod 5% cream and oral acitretin
    • doi:10.1046/j.1365-2230.28.s1.11.x
    • Giannotti B, Vanzi L, Difonzo EM, Pimpinelli N. The treatment of basal cell carcinomas in a patient with xeroderma pigmentosum with a combination of imiquimod 5% cream and oral acitretin. Clin Exp Dermatol (2003) 28(Suppl 1):33-5. doi:10.1046/j.1365-2230.28.s1.11.x
    • (2003) Clin Exp Dermatol , vol.28 , Issue.SUPPL. 1 , pp. 33-35
    • Giannotti, B.1    Vanzi, L.2    Difonzo, E.M.3    Pimpinelli, N.4
  • 52
    • 9144253900 scopus 로고    scopus 로고
    • Treatment of lentigo maligna with topical imiquimod
    • doi:10.1046/j.0366-077X.2003.05637.x
    • Naylor MF, Crowson N, Kuwahara R, Teague K, Garcia C, Mackinnis C, et al. Treatment of lentigo maligna with topical imiquimod. Br J Dermatol (2003) 149(Suppl 66):66-70. doi:10.1046/j.0366-077X.2003.05637.x
    • (2003) Br J Dermatol , vol.149 , Issue.SUPPL. 66 , pp. 66-70
    • Naylor, M.F.1    Crowson, N.2    Kuwahara, R.3    Teague, K.4    Garcia, C.5    Mackinnis, C.6
  • 53
    • 0347951007 scopus 로고    scopus 로고
    • The use of Toll-like receptor-7 agonist in the treatment of basal cell carcinoma: an overview
    • doi:10.1046/j.0366-077X.2003.05626.x
    • Stockfleth E, Trefzer U, Garcia-Bartels C, Wegner T, Schmook T, Sterry W. The use of Toll-like receptor-7 agonist in the treatment of basal cell carcinoma: an overview. Br J Dermatol (2003) 149(Suppl 66):53-6. doi:10.1046/j.0366-077X.2003.05626.x
    • (2003) Br J Dermatol , vol.149 , Issue.SUPPL. 66 , pp. 53-56
    • Stockfleth, E.1    Trefzer, U.2    Garcia-Bartels, C.3    Wegner, T.4    Schmook, T.5    Sterry, W.6
  • 54
    • 0036008014 scopus 로고    scopus 로고
    • Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway
    • doi:10.1038/ni758
    • Hemmi H, Kaisho T, Takeuchi O, Sato S, Sanjo H, Hoshino K, et al. Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway. Nat Immunol (2002) 3(2):196-200. doi:10.1038/ni758
    • (2002) Nat Immunol , vol.3 , Issue.2 , pp. 196-200
    • Hemmi, H.1    Kaisho, T.2    Takeuchi, O.3    Sato, S.4    Sanjo, H.5    Hoshino, K.6
  • 55
    • 27544470370 scopus 로고    scopus 로고
    • Viral and nonviral uses of imiquimod: a review
    • doi:10.1007/s10227-005-0023-5
    • Gupta AK, Cherman AM, Tyring SK. Viral and nonviral uses of imiquimod: a review. J Cutan Med Surg (2004) 8(5):338-52. doi:10.1007/s10227-005-0023-5
    • (2004) J Cutan Med Surg , vol.8 , Issue.5 , pp. 338-352
    • Gupta, A.K.1    Cherman, A.M.2    Tyring, S.K.3
  • 56
    • 3342911554 scopus 로고    scopus 로고
    • Immune modulation and apoptosis induction: two sides of the antitumoral activity of imiquimod
    • doi:10.1023/B:APPT.0000025805.55340.c3
    • Schon MP, Schon M. Immune modulation and apoptosis induction: two sides of the antitumoral activity of imiquimod. Apoptosis (2004) 9(3):291-8. doi:10.1023/B:APPT.0000025805.55340.c3
    • (2004) Apoptosis , vol.9 , Issue.3 , pp. 291-298
    • Schon, M.P.1    Schon, M.2
  • 57
    • 0036737628 scopus 로고    scopus 로고
    • Imiquimod 5% cream for the treatment of superficial basal cell carcinoma: a double-blind, randomized, vehicle-controlled study
    • doi:10.1067/mjd.2002.126215
    • Geisse JK, Rich P, Pandya A, Gross K, Andres K, Ginkel A, et al. Imiquimod 5% cream for the treatment of superficial basal cell carcinoma: a double-blind, randomized, vehicle-controlled study. J Am Acad Dermatol (2002) 47(3):390-8. doi:10.1067/mjd.2002.126215
    • (2002) J Am Acad Dermatol , vol.47 , Issue.3 , pp. 390-398
    • Geisse, J.K.1    Rich, P.2    Pandya, A.3    Gross, K.4    Andres, K.5    Ginkel, A.6
  • 58
    • 34848812857 scopus 로고    scopus 로고
    • Human basal cell carcinoma is associated with Foxp3+ T cells in a Th2 dominant microenvironment
    • doi:10.1038/sj.jid.5700884
    • Kaporis HG, Guttman-Yassky E, Lowes MA, Haider AS, Fuentes-Duculan J, Darabi K, et al. Human basal cell carcinoma is associated with Foxp3+ T cells in a Th2 dominant microenvironment. J Invest Dermatol (2007) 127(10):2391-8. doi:10.1038/sj.jid.5700884
    • (2007) J Invest Dermatol , vol.127 , Issue.10 , pp. 2391-2398
    • Kaporis, H.G.1    Guttman-Yassky, E.2    Lowes, M.A.3    Haider, A.S.4    Fuentes-Duculan, J.5    Darabi, K.6
  • 59
    • 84884815205 scopus 로고    scopus 로고
    • Imiquimod attenuates the growth of UVB-induced SCC in mice through Th1/Th17 cells
    • doi:10.1002/mc.21901
    • Yokogawa M, Takaishi M, Nakajima K, Kamijima R, Digiovanni J, Sano S. Imiquimod attenuates the growth of UVB-induced SCC in mice through Th1/Th17 cells. Mol Carcinog (2013) 52(10):760-9. doi:10.1002/mc.21901
    • (2013) Mol Carcinog , vol.52 , Issue.10 , pp. 760-769
    • Yokogawa, M.1    Takaishi, M.2    Nakajima, K.3    Kamijima, R.4    Digiovanni, J.5    Sano, S.6
  • 60
    • 0346690036 scopus 로고    scopus 로고
    • Imiquimod in basal cell carcinoma: how does it work?
    • doi:10.1046/j.0366-077X.2003.05630.x
    • Dummer R, Urosevic M, Kempf W, Hoek K, Hafner J, Burg G. Imiquimod in basal cell carcinoma: how does it work? Br J Dermatol (2003) 149(Suppl 66):57-8. doi:10.1046/j.0366-077X.2003.05630.x
    • (2003) Br J Dermatol , vol.149 , Issue.SUPPL. 66 , pp. 57-58
    • Dummer, R.1    Urosevic, M.2    Kempf, W.3    Hoek, K.4    Hafner, J.5    Burg, G.6
  • 61
    • 84870999117 scopus 로고    scopus 로고
    • Resiquimod, a topical drug for viral skin lesions and skin cancer
    • doi:10.1517/13543784.2013.749236
    • Meyer T, Surber C, French LE, Stockfleth E. Resiquimod, a topical drug for viral skin lesions and skin cancer. Expert Opin Investig Drugs (2013) 22(1):149-59. doi:10.1517/13543784.2013.749236
    • (2013) Expert Opin Investig Drugs , vol.22 , Issue.1 , pp. 149-159
    • Meyer, T.1    Surber, C.2    French, L.E.3    Stockfleth, E.4
  • 62
    • 0036037239 scopus 로고    scopus 로고
    • MyD88 is involved in the signalling pathway for Taxol-induced apoptosis and TNF-alpha expression in human myelomonocytic cells
    • doi:10.1046/j.1365-2141.2002.03645.x
    • Wang J, Kobayashi M, Han M, Choi S, Takano M, Hashino S, et al. MyD88 is involved in the signalling pathway for Taxol-induced apoptosis and TNF-alpha expression in human myelomonocytic cells. Br J Haematol (2002) 118(2):638-45. doi:10.1046/j.1365-2141.2002.03645.x
    • (2002) Br J Haematol , vol.118 , Issue.2 , pp. 638-645
    • Wang, J.1    Kobayashi, M.2    Han, M.3    Choi, S.4    Takano, M.5    Hashino, S.6
  • 63
    • 2342558523 scopus 로고    scopus 로고
    • Antitumor applications of stimulating toll-like receptor 9 with CpG oligodeoxynucleotides
    • doi:10.1007/s11912-004-0019-0
    • Krieg AM. Antitumor applications of stimulating toll-like receptor 9 with CpG oligodeoxynucleotides. Curr Oncol Rep (2004) 6(2):88-95. doi:10.1007/s11912-004-0019-0
    • (2004) Curr Oncol Rep , vol.6 , Issue.2 , pp. 88-95
    • Krieg, A.M.1
  • 64
    • 55249083982 scopus 로고    scopus 로고
    • Phase 1 evaluation of intralesionally injected TLR9-agonist PF-3512676 in patients with basal cell carcinoma or metastatic melanoma
    • doi:10.1097/CJI.0b013e318174a4df
    • Hofmann MA, Kors C, Audring H, Walden P, Sterry W, Trefzer U. Phase 1 evaluation of intralesionally injected TLR9-agonist PF-3512676 in patients with basal cell carcinoma or metastatic melanoma. J Immunother (2008) 31(5):520-7. doi:10.1097/CJI.0b013e318174a4df
    • (2008) J Immunother , vol.31 , Issue.5 , pp. 520-527
    • Hofmann, M.A.1    Kors, C.2    Audring, H.3    Walden, P.4    Sterry, W.5    Trefzer, U.6
  • 65
    • 56349092925 scopus 로고    scopus 로고
    • Cutaneous squamous cell carcinoma
    • doi:10.1016/j.yadr.2008.09.007
    • Garcia-Zuazaga J, Olbricht SM. Cutaneous squamous cell carcinoma. Adv Dermatol (2008) 24:33-57. doi:10.1016/j.yadr.2008.09.007
    • (2008) Adv Dermatol , vol.24 , pp. 33-57
    • Garcia-Zuazaga, J.1    Olbricht, S.M.2
  • 66
    • 84872332945 scopus 로고    scopus 로고
    • Expression of TLR3, 4, 7 and 9 in cutaneous malignant melanoma: relationship with clinicopathological characteristics and prognosis
    • doi:10.1007/s00403-012-1300-y
    • Eiro N, Ovies C, Fernandez-Garcia B, Alvarez-Cuesta CC, Gonzalez L, Gonzalez LO, et al. Expression of TLR3, 4, 7 and 9 in cutaneous malignant melanoma: relationship with clinicopathological characteristics and prognosis. Arch Dermatol Res (2013) 305(1):59-67. doi:10.1007/s00403-012-1300-y
    • (2013) Arch Dermatol Res , vol.305 , Issue.1 , pp. 59-67
    • Eiro, N.1    Ovies, C.2    Fernandez-Garcia, B.3    Alvarez-Cuesta, C.C.4    Gonzalez, L.5    Gonzalez, L.O.6
  • 67
    • 33845627116 scopus 로고    scopus 로고
    • Toll-like receptor interactions: tolerance of MyD88-dependent cytokines but enhancement of MyD88-independent interferon-beta production
    • doi:10.1111/j.1365-2567.2006.02485.x
    • Broad A, Kirby JA, Jones DE, Applied I, Transplantation Research G. Toll-like receptor interactions: tolerance of MyD88-dependent cytokines but enhancement of MyD88-independent interferon-beta production. Immunology (2007) 120(1):103-11. doi:10.1111/j.1365-2567.2006.02485.x
    • (2007) Immunology , vol.120 , Issue.1 , pp. 103-111
    • Broad, A.1    Kirby, J.A.2    Jones, D.E.3    Applied, I.4    Transplantation Research, G.5
  • 68
    • 68949103827 scopus 로고    scopus 로고
    • In vivo lipopolysaccharide exposure of human blood leukocytes induces cross-tolerance to multiple TLR ligands
    • doi:10.4049/jimmunol.0802189
    • de Vos AF, Pater JM, van den Pangaart PS, de Kruif MD, van't Veer C, van der Poll T. In vivo lipopolysaccharide exposure of human blood leukocytes induces cross-tolerance to multiple TLR ligands. J Immunol (2009) 183(1):533-42. doi:10.4049/jimmunol.0802189
    • (2009) J Immunol , vol.183 , Issue.1 , pp. 533-542
    • de Vos, A.F.1    Pater, J.M.2    van den Pangaart, P.S.3    de Kruif, M.D.4    van't Veer, C.5    van der Poll, T.6
  • 69
    • 79960956913 scopus 로고    scopus 로고
    • Systemic cancer therapy with a small molecule agonist of toll-like receptor 7 can be improved by circumventing TLR tolerance
    • doi:10.1158/0008-5472.CAN-10-3903
    • Bourquin C, Hotz C, Noerenberg D, Voelkl A, Heidegger S, Roetzer LC, et al. Systemic cancer therapy with a small molecule agonist of toll-like receptor 7 can be improved by circumventing TLR tolerance. Cancer Res (2011) 71(15):5123-33. doi:10.1158/0008-5472.CAN-10-3903
    • (2011) Cancer Res , vol.71 , Issue.15 , pp. 5123-5133
    • Bourquin, C.1    Hotz, C.2    Noerenberg, D.3    Voelkl, A.4    Heidegger, S.5    Roetzer, L.C.6


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