-
1
-
-
0030831210
-
A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
-
Medzhitov R, Preston-Hurlburt P, Janeway CA, Jr. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 1997;388:394-7.
-
(1997)
Nature
, vol.388
, pp. 394-397
-
-
Medzhitov, R.1
Preston-Hurlburt, P.2
Janeway Jr, C.A.3
-
3
-
-
0034443265
-
Maturation of human dendritic cells by cell wall skeleton of Mycobacterium bovis bacillus Calmette-Guerin: Involvement of toll-like receptors
-
Tsuji S, Matsumoto M, Takeuchi O, et al. Maturation of human dendritic cells by cell wall skeleton of Mycobacterium bovis bacillus Calmette-Guerin: involvement of toll-like receptors. Infect Immun 2000;68:6883-90.
-
(2000)
Infect Immun
, vol.68
, pp. 6883-6890
-
-
Tsuji, S.1
Matsumoto, M.2
Takeuchi, O.3
-
4
-
-
0043267978
-
Simultaneous blocking of human Toll-like receptors 2 and 4 suppresses myeloid dendritic cell activation induced by Mycobacterium bovis bacillus Calmette-Guerin peptidoglycan
-
Uehori J, Matsumoto M, Tsuji S, et al. Simultaneous blocking of human Toll-like receptors 2 and 4 suppresses myeloid dendritic cell activation induced by Mycobacterium bovis bacillus Calmette-Guerin peptidoglycan. Infect Immun 2003;71:4238-49.
-
(2003)
Infect Immun
, vol.71
, pp. 4238-4249
-
-
Uehori, J.1
Matsumoto, M.2
Tsuji, S.3
-
5
-
-
33645889669
-
Melanoma cell lines are responsive in vitro to lipopolysaccharide and express TLR-4
-
Molteni M, Marabella D, Orlandi C, Rossetti C. Melanoma cell lines are responsive in vitro to lipopolysaccharide and express TLR-4. Cancer Lett 2006;235:75-83.
-
(2006)
Cancer Lett
, vol.235
, pp. 75-83
-
-
Molteni, M.1
Marabella, D.2
Orlandi, C.3
Rossetti, C.4
-
6
-
-
35348813788
-
Identification of Toll-like receptor 3 as a potential therapeutic target in clear cell renal cell carcinoma
-
Morikawa T, Sugiyama A, Kume H, et al. Identification of Toll-like receptor 3 as a potential therapeutic target in clear cell renal cell carcinoma. Clin Cancer Res 2007;13:5703-9.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 5703-5709
-
-
Morikawa, T.1
Sugiyama, A.2
Kume, H.3
-
7
-
-
33645727988
-
TLR-4 signaling promotes tumor growth and paclitaxel chemoresistance in ovarian cancer
-
Kelly MG, Alvero AB, Chen R, et al. TLR-4 signaling promotes tumor growth and paclitaxel chemoresistance in ovarian cancer. Cancer Res 2006;66:3859-68.
-
(2006)
Cancer Res
, vol.66
, pp. 3859-3868
-
-
Kelly, M.G.1
Alvero, A.B.2
Chen, R.3
-
8
-
-
34547665101
-
Toll-like receptor 3 expressed by melanoma cells as a target for therapy?
-
Salaun B, Lebecque S, Matikainen S, Rimoldi D, Romero P. Toll-like receptor 3 expressed by melanoma cells as a target for therapy? Clin Cancer Res 2007;13:4565-74.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 4565-4574
-
-
Salaun, B.1
Lebecque, S.2
Matikainen, S.3
Rimoldi, D.4
Romero, P.5
-
10
-
-
0035901090
-
Inflammation and cancer: Back to Virchow?
-
Balkwill F, Mantovani A. Inflammation and cancer: back to Virchow? Lancet 2001;357:539-45.
-
(2001)
Lancet
, vol.357
, pp. 539-545
-
-
Balkwill, F.1
Mantovani, A.2
-
11
-
-
0037180757
-
Inflammation and cancer
-
Coussens LM, Werb Z. Inflammation and cancer. Nature 2002;420:860-7.
-
(2002)
Nature
, vol.420
, pp. 860-867
-
-
Coussens, L.M.1
Werb, Z.2
-
12
-
-
25844490025
-
The interplay between innate and adaptive immunity regulates cancer development
-
de Visser KE, Coussens LM. The interplay between innate and adaptive immunity regulates cancer development. Cancer Immunol Immunother 2005;54:1143-52.
-
(2005)
Cancer Immunol Immunother
, vol.54
, pp. 1143-1152
-
-
de Visser, K.E.1
Coussens, L.M.2
-
13
-
-
20444441548
-
Cancer: Inflammation by remote control
-
Mantovani A. Cancer: inflammation by remote control. Nature 2005;435:752-3.
-
(2005)
Nature
, vol.435
, pp. 752-753
-
-
Mantovani, A.1
-
14
-
-
16444373352
-
Epigenetic up-regulation of C-C chemokine receptor 7 and C-X-C chemokine receptor 4 expression in melanoma cells
-
Mori T, Kim J, Yamano T, et al. Epigenetic up-regulation of C-C chemokine receptor 7 and C-X-C chemokine receptor 4 expression in melanoma cells. Cancer Res 2005;65:1800-7.
-
(2005)
Cancer Res
, vol.65
, pp. 1800-1807
-
-
Mori, T.1
Kim, J.2
Yamano, T.3
-
15
-
-
0030955030
-
Melanoma-associated antigens as messenger RNA detection markers for melanoma
-
Sarantou T, Chi DD, Garrison DA, et al. Melanoma-associated antigens as messenger RNA detection markers for melanoma. Cancer Res 1997;57:1371-6.
-
(1997)
Cancer Res
, vol.57
, pp. 1371-1376
-
-
Sarantou, T.1
Chi, D.D.2
Garrison, D.A.3
-
16
-
-
1842479075
-
CCL21 chemokine regulates chemokine receptor CCR7 bearing malignant melanoma cells
-
Takeuchi H, Fujimoto A, Tanaka M, Yamano T, Hsueh E, Hoon DS. CCL21 chemokine regulates chemokine receptor CCR7 bearing malignant melanoma cells. Clin Cancer Res 2004;10:2351-8.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 2351-2358
-
-
Takeuchi, H.1
Fujimoto, A.2
Tanaka, M.3
Yamano, T.4
Hsueh, E.5
Hoon, D.S.6
-
17
-
-
0141973806
-
Prediction of disease outcome in melanoma patients by molecular analysis of paraffin-embedded sentinel lymph nodes
-
Kuo CT, Hoon DS, Takeuchi H, et al. Prediction of disease outcome in melanoma patients by molecular analysis of paraffin-embedded sentinel lymph nodes. J Clin Oncol 2003;21:3566-72.
-
(2003)
J Clin Oncol
, vol.21
, pp. 3566-3572
-
-
Kuo, C.T.1
Hoon, D.S.2
Takeuchi, H.3
-
18
-
-
32944480188
-
Serial monitoring of circulating melanoma cells during neoadjuvant biochemotherapy for stage III melanoma: Outcome prediction in a multicenter trial
-
Koyanagi K, O'Day SJ, Gonzalez R, et al. Serial monitoring of circulating melanoma cells during neoadjuvant biochemotherapy for stage III melanoma: outcome prediction in a multicenter trial. J Clin Oncol 2005;23:8057-64.
-
(2005)
J Clin Oncol
, vol.23
, pp. 8057-8064
-
-
Koyanagi, K.1
O'Day, S.J.2
Gonzalez, R.3
-
19
-
-
4344590283
-
Prognostic significance of molecular upstaging of paraffin-embedded sentinel lymph nodes in melanoma patients
-
Takeuchi H, Morton DL, Kuo C, et al. Prognostic significance of molecular upstaging of paraffin-embedded sentinel lymph nodes in melanoma patients. J Clin Oncol 2004;22:2671-80.
-
(2004)
J Clin Oncol
, vol.22
, pp. 2671-2680
-
-
Takeuchi, H.1
Morton, D.L.2
Kuo, C.3
-
20
-
-
33646255115
-
A new melanoma antigen fatty acid-binding protein 7, involved in proliferation and invasion, is a potential target for immunotherapy and molecular target therapy
-
Goto Y, Matsuzaki Y, Kurihara S, et al. A new melanoma antigen fatty acid-binding protein 7, involved in proliferation and invasion, is a potential target for immunotherapy and molecular target therapy. Cancer Res 2006;66:4443-9.
-
(2006)
Cancer Res
, vol.66
, pp. 4443-4449
-
-
Goto, Y.1
Matsuzaki, Y.2
Kurihara, S.3
-
21
-
-
0038714270
-
Poly(I-C)-induced Toll-like receptor 3 (TLR3)-mediated activation of NFnB and MAP kinase is through an interleukin-1 receptor-associated kinase (IRAK)-independent pathway employing the signaling components TLR3-6-TAK1-2-PKR
-
Jiang Z, Zamanian-Daryoush M, Nie H, Silva AM, Williams BR, Li X. Poly(I-C)-induced Toll-like receptor 3 (TLR3)-mediated activation of NFnB and MAP kinase is through an interleukin-1 receptor-associated kinase (IRAK)-independent pathway employing the signaling components TLR3-6-TAK1-2-PKR. J Biol Chem 2003;278:16713-9.
-
(2003)
J Biol Chem
, vol.278
, pp. 16713-16719
-
-
Jiang, Z.1
Zamanian-Daryoush, M.2
Nie, H.3
Silva, A.M.4
Williams, B.R.5
Li, X.6
-
22
-
-
11144232998
-
Human high molecular weight-melanoma-associated antigen (HMW-MAA): A melanoma cell surface chondroitin sulfate proteoglycan (MSCP) with biological and clinical significance
-
Campoli MR, Chang CC, Kageshita T, Wang X, McCarthy JB, Ferrone S. Human high molecular weight-melanoma-associated antigen (HMW-MAA): a melanoma cell surface chondroitin sulfate proteoglycan (MSCP) with biological and clinical significance. Crit Rev Immunol 2004;24:267-96.
-
(2004)
Crit Rev Immunol
, vol.24
, pp. 267-296
-
-
Campoli, M.R.1
Chang, C.C.2
Kageshita, T.3
Wang, X.4
McCarthy, J.B.5
Ferrone, S.6
-
23
-
-
20444366947
-
Adaptor usage and Toll-like receptor signaling specificity
-
Dunne A, O'Neill LA. Adaptor usage and Toll-like receptor signaling specificity. FEBS Lett 2005;579:3330-5.
-
(2005)
FEBS Lett
, vol.579
, pp. 3330-3335
-
-
Dunne, A.1
O'Neill, L.A.2
-
24
-
-
0037351927
-
Toll-like receptor-4 (TLR4) signaling augments chemokine-induced neutrophil migration by modulating cell surface expression of chemokine receptors
-
Fan J, Malik AB. Toll-like receptor-4 (TLR4) signaling augments chemokine-induced neutrophil migration by modulating cell surface expression of chemokine receptors. Nat Med 2003;9:315-21.
-
(2003)
Nat Med
, vol.9
, pp. 315-321
-
-
Fan, J.1
Malik, A.B.2
-
25
-
-
0032802166
-
Detection of tumor messenger RNA in the serum of patients with malignant melanoma
-
Kopreski MS, Benko FA, Kwak LW, Gocke CD. Detection of tumor messenger RNA in the serum of patients with malignant melanoma. Clin Cancer Res 1999;5:1961-5.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 1961-1965
-
-
Kopreski, M.S.1
Benko, F.A.2
Kwak, L.W.3
Gocke, C.D.4
-
26
-
-
18444415477
-
Presence of filterable and nonfilterable mRNA in the plasma of cancer patients and healthy individuals
-
Ng EK, Tsui NB, Lam NY, et al. Presence of filterable and nonfilterable mRNA in the plasma of cancer patients and healthy individuals. Clin Chem 2002;48:1212-7.
-
(2002)
Clin Chem
, vol.48
, pp. 1212-1217
-
-
Ng, E.K.1
Tsui, N.B.2
Lam, N.Y.3
-
27
-
-
33751566641
-
Human langerhans cells express a specific TLR profile and differentially respond to viruses and Gram-positive bacteria
-
Flacher V, Bouschbacher M, Verronese E, et al. Human langerhans cells express a specific TLR profile and differentially respond to viruses and Gram-positive bacteria. J Immunol 2006;177:7959-67.
-
(2006)
J Immunol
, vol.177
, pp. 7959-7967
-
-
Flacher, V.1
Bouschbacher, M.2
Verronese, E.3
-
28
-
-
20144389424
-
Various members of the Toll-like receptor family contribute to the innate immune response of human epidermal keratinocytes
-
Kollisch G, Kalali BN, Voelcker V, et al. Various members of the Toll-like receptor family contribute to the innate immune response of human epidermal keratinocytes. Immunology 2005;114:531-41.
-
(2005)
Immunology
, vol.114
, pp. 531-541
-
-
Kollisch, G.1
Kalali, B.N.2
Voelcker, V.3
-
29
-
-
3142724031
-
Toll-like receptor signalling
-
Akira S, Takeda K. Toll-like receptor signalling. Nat Rev Immunol 2004;4:499-511.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 499-511
-
-
Akira, S.1
Takeda, K.2
-
30
-
-
0141431027
-
Tumour necrosis factor a: A potential target for the therapy of solid tumours
-
Szlosarek PW, Balkwill FR. Tumour necrosis factor a: a potential target for the therapy of solid tumours. Lancet Oncol 2003;4:565-73.
-
(2003)
Lancet Oncol
, vol.4
, pp. 565-573
-
-
Szlosarek, P.W.1
Balkwill, F.R.2
-
31
-
-
0036005888
-
Tumor necrosis factor or tumor promoting factor?
-
Balkwill F. Tumor necrosis factor or tumor promoting factor? Cytokine Growth Factor Rev 2002;13:135-41.
-
(2002)
Cytokine Growth Factor Rev
, vol.13
, pp. 135-141
-
-
Balkwill, F.1
-
32
-
-
0347123433
-
Tumour-educated macrophages promote tumour progression and metastasis
-
Pollard JW. Tumour-educated macrophages promote tumour progression and metastasis. Nat Rev Cancer 2004;4:71-8.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 71-78
-
-
Pollard, J.W.1
-
33
-
-
18644380441
-
The CXCL10/CXCR3 axis mediates human lung mast cell migration to asthmatic airway smooth muscle
-
Brightling CE, Ammit AJ, Kaur D, et al. The CXCL10/CXCR3 axis mediates human lung mast cell migration to asthmatic airway smooth muscle. Am J Respir Crit Care Med 2005;171:1103-8.
-
(2005)
Am J Respir Crit Care Med
, vol.171
, pp. 1103-1108
-
-
Brightling, C.E.1
Ammit, A.J.2
Kaur, D.3
-
34
-
-
36849003543
-
Epigenetic silencing of cyclooxygenase-2 affects clinical outcome in gastric cancer
-
de Maat MF, van de Velde CJ, Umetani N, et al. Epigenetic silencing of cyclooxygenase-2 affects clinical outcome in gastric cancer. J Clin Oncol 2007;25:4887-94.
-
(2007)
J Clin Oncol
, vol.25
, pp. 4887-4894
-
-
de Maat, M.F.1
van de Velde, C.J.2
Umetani, N.3
-
35
-
-
0036530016
-
CD4(+) and CD8(+) anergic T cells induced by interleukin-10-treated human dendritic cells display antigen-specific suppressor activity
-
Steinbrink K, Graulich E, Kubsch S, Knop J, Enk AH. CD4(+) and CD8(+) anergic T cells induced by interleukin-10-treated human dendritic cells display antigen-specific suppressor activity. Blood 2002;99:2468-76.
-
(2002)
Blood
, vol.99
, pp. 2468-2476
-
-
Steinbrink, K.1
Graulich, E.2
Kubsch, S.3
Knop, J.4
Enk, A.H.5
-
36
-
-
4043088499
-
IKKβ links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
-
Greten FR, Eckmann L, Greten TF, et al. IKKβ links inflammation and tumorigenesis in a mouse model of colitis-associated cancer. Cell 2004;118:285-96.
-
(2004)
Cell
, vol.118
, pp. 285-296
-
-
Greten, F.R.1
Eckmann, L.2
Greten, T.F.3
-
37
-
-
4644324186
-
NF-κB functions as a tumour promoter in inflammation-associated cancer
-
Pikarsky E, Porat RM, Stein I, et al. NF-κB functions as a tumour promoter in inflammation-associated cancer. Nature 2004;431:461-6.
-
(2004)
Nature
, vol.431
, pp. 461-466
-
-
Pikarsky, E.1
Porat, R.M.2
Stein, I.3
-
38
-
-
31344471171
-
Toll-like receptors, inflammation and cancer
-
Tsan MF. Toll-like receptors, inflammation and cancer. Semin Cancer Biol 2006;16:32-7.
-
(2006)
Semin Cancer Biol
, vol.16
, pp. 32-37
-
-
Tsan, M.F.1
-
39
-
-
1842477469
-
mRNA is an endogenous ligand for Toll-like receptor 3
-
Kariko K, Ni H, Capodici J, Lamphier M, Weissman D. mRNA is an endogenous ligand for Toll-like receptor 3. J Biol Chem 2004;279:12542-50.
-
(2004)
J Biol Chem
, vol.279
, pp. 12542-12550
-
-
Kariko, K.1
Ni, H.2
Capodici, J.3
Lamphier, M.4
Weissman, D.5
-
40
-
-
33847183077
-
Cooperation of Toll-like receptor signals in innate immune defence
-
Trinchieri G, Sher A. Cooperation of Toll-like receptor signals in innate immune defence. Nat Rev Immunol 2007;7:179-90.
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 179-190
-
-
Trinchieri, G.1
Sher, A.2
-
41
-
-
37849035627
-
TLR signaling by tumor and immune cells: A double-edged sword
-
Huang B, Zhao J, Unkeless JC, Feng ZH, Xiong H. TLR signaling by tumor and immune cells: a double-edged sword. Oncogene 2008;27:218-24.
-
(2008)
Oncogene
, vol.27
, pp. 218-224
-
-
Huang, B.1
Zhao, J.2
Unkeless, J.C.3
Feng, Z.H.4
Xiong, H.5
-
42
-
-
38649123396
-
The future of toll-like receptor therapeutics
-
Parkinson T. The future of toll-like receptor therapeutics. Curr Opin Mol Ther 2008;10:21-31.
-
(2008)
Curr Opin Mol Ther
, vol.10
, pp. 21-31
-
-
Parkinson, T.1
|